Or5w12 (olfactory receptor family 5 subfamily W member 12) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Or5w12 (olfactory receptor family 5 subfamily W member 12) Mus musculus
Analyze
No known orthologs.
Symbol: Or5w12
Name: olfactory receptor family 5 subfamily W member 12
RGD ID: 1550120
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2Q125-49177531-49176599; MOR177; MOR177-2; olfactory receptor 1135; olfactory receptor MOR177-2; Olfr1135
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Pseudogenes: Gm18179  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39287,501,777 - 87,502,709 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl287,500,179 - 87,504,008 (-)EnsemblGRCm39 Ensembl
GRCm38287,671,433 - 87,672,365 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl287,669,835 - 87,673,664 (-)EnsemblGRCm38mm10GRCm38
MGSCv37287,511,590 - 87,512,522 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36287,472,272 - 87,473,204 (-)NCBIMGSCv36mm8
Celera289,281,305 - 89,282,237 (-)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or5w12Mouse4,4'-diaminodiphenylmethane increases expressionEXP 64804644 and 4'-diaminodiphenylmethane results in increased expression of OR5W12 mRNACTDPMID:18648102


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or5w12MouseG protein-coupled receptor signaling pathway acts_upstream_of_or_withinISAUniProtKB:Q951552290270 PMID:14611657MGIPMID:14611657
Or5w12Mousesensory perception of smell acts_upstream_of_or_withinISAUniProtKB:Q951552290270 PMID:14611657MGIPMID:14611657

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or5w12Mousemembrane located_inISAUniProtKB:Q951552290270 PMID:14611657MGIPMID:14611657

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or5w12Mouseodorant binding enablesIBAPANTHER:PTN001241937 more ...2290270 GO_CentralGO_REF:0000033
Or5w12Mouseolfactory receptor activity enablesIBAPANTHER:PTN001241937 more ...2290270 GO_CentralGO_REF:0000033
Or5w12Mouseolfactory receptor activity enablesISAUniProtKB:Q951552290270 PMID:14611657MGIPMID:14611657


#
Reference Title
Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:11802173   PMID:11875048   PMID:14611657   PMID:21873635   PMID:32295537  



.

.
Variants in Or5w12
30 total Variants

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:58
Interacting mature miRNAs:60
Transcripts:ENSMUST00000099853
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 47 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286095716120095823Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286095716120095823Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse

1 to 10 of 47 rows
UniSTS:485137  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38287,671,433 - 87,672,365UniSTSGRCm38
MGSCv37287,511,590 - 87,512,522UniSTSGRCm37
Celera289,281,305 - 89,282,237UniSTS
Cytogenetic Map2E1UniSTS
UniSTS:495622  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38287,671,373 - 87,672,395UniSTSGRCm38
MGSCv37287,511,530 - 87,512,552UniSTSGRCm37
Celera289,281,245 - 89,282,267UniSTS
Cytogenetic Map2E1UniSTS







Ensembl Acc Id: ENSMUST00000099853   ⟹   ENSMUSP00000097439
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl287,501,777 - 87,502,709 (-)Ensembl
GRCm38.p6 Ensembl287,671,433 - 87,672,365 (-)Ensembl
Ensembl Acc Id: ENSMUST00000213835   ⟹   ENSMUSP00000150079
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl287,500,179 - 87,504,008 (-)Ensembl
GRCm38.p6 Ensembl287,669,835 - 87,673,664 (-)Ensembl
RefSeq Acc Id: NM_146660   ⟹   NP_666871
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39287,501,777 - 87,502,709 (-)NCBI
GRCm38287,671,433 - 87,672,365 (-)ENTREZGENE
MGSCv37287,511,590 - 87,512,522 (-)RGD
Celera289,281,305 - 89,282,237 (-)RGD
cM Map2 ENTREZGENE
Sequence:
Protein RefSeqs NP_666871 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL61099 (Get FASTA)   NCBI Sequence Viewer  
  AAP71554 (Get FASTA)   NCBI Sequence Viewer  
  EDL27404 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000097439
  ENSMUSP00000097439.2
  ENSMUSP00000150079.2
RefSeq Acc Id: NP_666871   ⟸   NM_146660
- UniProtKB: Q7TR42 (UniProtKB/TrEMBL),   Q8VFT0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000097439   ⟸   ENSMUST00000099853
Ensembl Acc Id: ENSMUSP00000150079   ⟸   ENSMUST00000213835
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-Q7TR42-F1-model_v2 AlphaFold Q7TR42 1-310 view protein structure



1 to 21 of 21 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000075153 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000099853 ENTREZGENE
  ENSMUST00000099853.2 UniProtKB/TrEMBL
  ENSMUST00000213835.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258654 UniProtKB/TrEMBL
MGD MGI:3030969 ENTREZGENE
NCBI Gene 258654 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5w12 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q7TR42 ENTREZGENE, UniProtKB/TrEMBL
  Q8VFT0 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or5w12  olfactory receptor family 5 subfamily W member 12  Olfr1135  olfactory receptor 1135  Symbol and/or name change 5135510 APPROVED