MIR214 (microRNA mir-214) - Rat Genome Database

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Gene: MIR214 (microRNA mir-214) Sus scrofa
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Symbol: MIR214
Name: microRNA mir-214
RGD ID: 14294798
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: microRNA 214; ssc-mir-214
RGD Orthologs
Human
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9114,527,990 - 114,528,101 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19114,527,992 - 114,528,101 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29126,099,461 - 126,099,570 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:15885146   PMID:16381832   PMID:21312241   PMID:25230983   PMID:30051550  


Genomics

Comparative Map Data
MIR214
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9114,527,990 - 114,528,101 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19114,527,992 - 114,528,101 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29126,099,461 - 126,099,570 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIR214
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1172,138,798 - 172,138,907 (-)EnsemblGRCh38hg38GRCh38
GRCh381172,138,798 - 172,138,907 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371172,107,938 - 172,108,047 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361170,374,560 - 170,374,669 (-)NCBINCBI36hg18NCBI36
Celera1145,217,369 - 145,217,478 (-)NCBI
Cytogenetic Map1q24.3NCBI
HuRef1143,331,930 - 143,332,039 (-)NCBIHuRef
CHM1_11173,530,115 - 173,530,224 (-)NCBICHM1_1
Mir214
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391162,050,937 - 162,051,046 (+)NCBIGRCm39mm39
GRCm39 Ensembl1162,050,937 - 162,051,046 (+)Ensembl
GRCm381162,223,368 - 162,223,477 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1162,223,368 - 162,223,477 (+)EnsemblGRCm38mm10GRCm38
MGSCv371164,153,499 - 164,153,608 (+)NCBIGRCm37mm9NCBIm37
Celera1164,673,727 - 164,673,836 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
MIR214
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1726,818,559 - 26,818,668 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl726,818,559 - 26,818,670 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha726,349,187 - 26,349,296 (+)NCBI
ROS_Cfam_1.0726,569,331 - 26,569,440 (+)NCBI
UMICH_Zoey_3.1726,480,256 - 26,480,365 (+)NCBI
UNSW_CanFamBas_1.0726,551,084 - 26,551,193 (+)NCBI
UU_Cfam_GSD_1.0726,701,038 - 26,701,147 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 7 2 4 2 6 3 1
Low 3 1 3 1 14 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000020353
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9114,527,990 - 114,528,101 (-)Ensembl
RefSeq Acc Id: NR_038497
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19114,527,992 - 114,528,101 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000018758 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000020353 ENTREZGENE
miRBase MI0002441 ENTREZGENE
NCBI Gene MIR214 ENTREZGENE
RNAcentral URS00002524E1 RNACentral
  URS00004DAA89 RNACentral
  URS00005F8A9C RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR214  microRNA mir-214    microRNA 214  Symbol and/or name change 5135510 APPROVED