ZFYVE19 (zinc finger FYVE-type containing 19) - Rat Genome Database

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Gene: ZFYVE19 (zinc finger FYVE-type containing 19) Sus scrofa
Analyze
Symbol: ZFYVE19
Name: zinc finger FYVE-type containing 19
RGD ID: 14246156
Description: ENCODES a protein that exhibits metal ion binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN midbody abscission (inferred); mitotic cytokinesis checkpoint signaling (inferred); negative regulation of cytokinesis (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); mosaic variegated aneuploidy syndrome 1 (ortholog); FOUND IN centrosome (inferred); cleavage furrow (inferred); midbody (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: abscission/NoCut checkpoint regulator
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1130,510,719 - 130,517,216 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11130,510,718 - 130,517,943 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21145,668,920 - 145,675,472 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZFYVE19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1130,510,719 - 130,517,216 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11130,510,718 - 130,517,943 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21145,668,920 - 145,675,472 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZFYVE19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381540,807,089 - 40,815,084 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1540,807,086 - 40,815,084 (+)EnsemblGRCh38hg38GRCh38
GRCh371541,099,287 - 41,107,282 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,886,566 - 38,894,059 (+)NCBINCBI36Build 36hg18NCBI36
Build 341538,886,723 - 38,894,059NCBI
Celera1517,867,170 - 17,874,666 (+)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1517,947,391 - 17,955,209 (+)NCBIHuRef
CHM1_11541,219,288 - 41,227,088 (+)NCBICHM1_1
T2T-CHM13v2.01538,613,113 - 38,621,110 (+)NCBIT2T-CHM13v2.0
Zfyve19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392119,039,088 - 119,047,531 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2119,039,098 - 119,047,530 (+)EnsemblGRCm39 Ensembl
GRCm382119,208,607 - 119,217,050 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,208,617 - 119,217,049 (+)EnsemblGRCm38mm10GRCm38
MGSCv372119,034,456 - 119,042,786 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362118,900,398 - 118,908,490 (+)NCBIMGSCv36mm8
Celera2120,358,842 - 120,367,201 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.97NCBI
Zfyve19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83126,649,625 - 126,657,812 (+)NCBIGRCr8
mRatBN7.23106,195,779 - 106,203,969 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3106,195,899 - 106,203,969 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3109,869,190 - 109,877,060 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03118,464,732 - 118,472,603 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03116,125,110 - 116,132,980 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03111,013,856 - 111,021,841 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3111,013,856 - 111,021,841 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03117,564,417 - 117,583,944 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,722,207 - 105,730,192 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3105,109,218 - 105,117,203 (+)NCBICelera
Cytogenetic Map3q35NCBI
Zfyve19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554167,672,592 - 7,679,632 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554167,672,499 - 7,679,851 (+)NCBIChiLan1.0ChiLan1.0
ZFYVE19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21630,048,198 - 30,055,226 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11534,199,702 - 34,206,663 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01519,747,606 - 19,755,185 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11537,999,283 - 38,006,744 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1537,999,283 - 38,006,744 (+)Ensemblpanpan1.1panPan2
ZFYVE19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1307,945,364 - 7,952,751 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl307,945,407 - 7,952,751 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha308,000,012 - 8,007,396 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0308,073,769 - 8,081,163 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl308,073,781 - 8,083,323 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1307,996,443 - 8,003,825 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0308,104,012 - 8,111,396 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0308,233,304 - 8,240,688 (+)NCBIUU_Cfam_GSD_1.0
Zfyve19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864086,355,618 - 86,359,269 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364714,203,391 - 4,207,332 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFYVE19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12642,186,708 - 42,194,750 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2642,184,668 - 42,193,473 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604898,787,370 - 98,794,452 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zfyve19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248048,056,529 - 8,063,160 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248048,056,391 - 8,063,483 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZFYVE19
100 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000005260   ⟹   ENSSSCP00000005133
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1130,510,722 - 130,517,222 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000071011   ⟹   ENSSSCP00000073619
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1130,510,981 - 130,517,211 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000075866   ⟹   ENSSSCP00000068032
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1130,511,009 - 130,517,216 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000085687   ⟹   ENSSSCP00000068330
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1130,510,719 - 130,516,998 (-)Ensembl
RefSeq Acc Id: XM_001929402   ⟹   XP_001929437
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11130,510,718 - 130,517,943 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005659745   ⟹   XP_005659802
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11130,510,718 - 130,516,704 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001929437 (Get FASTA)   NCBI Sequence Viewer  
  XP_005659802 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000068032
  ENSSSCP00000068032.1
  ENSSSCP00000068330.1
RefSeq Acc Id: XP_001929437   ⟸   XM_001929402
- UniProtKB: A0A480DPI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005659802   ⟸   XM_005659745
- UniProtKB: A0A480DPI8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000005133   ⟸   ENSSSCT00000005260
Ensembl Acc Id: ENSSSCP00000068032   ⟸   ENSSSCT00000075866
Ensembl Acc Id: ENSSSCP00000073619   ⟸   ENSSSCT00000071011
Ensembl Acc Id: ENSSSCP00000068330   ⟸   ENSSSCT00000085687
Protein Domains
FYVE-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004761 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000075866 ENTREZGENE
  ENSSSCT00000075866.1 UniProtKB/TrEMBL
  ENSSSCT00000085687.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Bbox1_ANCHR UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene ZFYVE19 ENTREZGENE
PANTHER ABSCISSION/NOCUT CHECKPOINT REGULATOR UniProtKB/TrEMBL
  ABSCISSION/NOCUT CHECKPOINT REGULATOR UniProtKB/TrEMBL
Pfam ANCHR-like_BBOX UniProtKB/TrEMBL
  FYVE UniProtKB/TrEMBL
PROSITE ZF_FYVE UniProtKB/TrEMBL
SMART FYVE UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A480DPI8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UR68_PIG UniProtKB/TrEMBL
  A0A5G2R1F7_PIG UniProtKB/TrEMBL
UniProt Secondary A0A5G2QW03 UniProtKB/TrEMBL
VGNC ID VGNC:95158 ENTREZGENE