PPP2R5C (protein phosphatase 2 regulatory subunit B'gamma) - Rat Genome Database

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Gene: PPP2R5C (protein phosphatase 2 regulatory subunit B'gamma) Sus scrofa
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Symbol: PPP2R5C
Name: protein phosphatase 2 regulatory subunit B'gamma
RGD ID: 14245194
Description: ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (ortholog); intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (ortholog); negative regulation of cell population proliferation (ortholog); ASSOCIATED WITH autosomal recessive intellectual developmental disorder 41 (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog); Charcot-Marie-Tooth disease axonal type 2O (ortholog); FOUND IN chromosome, centromeric region (ortholog); cytosol (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27129,864,473 - 129,957,091 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PPP2R5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27129,864,473 - 129,957,091 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP2R5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,760,573 - 101,927,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,761,709 - 101,927,989 (+)EnsemblGRCh38hg38GRCh38
GRCh3714102,226,910 - 102,394,329 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614101,345,925 - 101,463,831 (+)NCBINCBI36Build 36hg18NCBI36
Build 3414101,345,924 - 101,442,736NCBI
Celera1482,282,956 - 82,448,834 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1482,408,998 - 82,573,806 (+)NCBIHuRef
CHM1_114102,166,309 - 102,332,185 (+)NCBICHM1_1
T2T-CHM13v2.01495,996,275 - 96,163,606 (+)NCBIT2T-CHM13v2.0
Ppp2r5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912110,413,532 - 110,549,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12110,413,554 - 110,549,496 (+)EnsemblGRCm39 Ensembl
GRCm3812110,447,144 - 110,583,075 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12110,447,120 - 110,583,062 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712111,685,389 - 111,821,271 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612110,933,696 - 111,028,359 (+)NCBIMGSCv36mm8
Celera12111,641,643 - 111,773,413 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.56NCBI
Ppp2r5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86135,282,947 - 135,419,591 (+)NCBIGRCr8
mRatBN7.26129,461,689 - 129,598,344 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6129,461,648 - 129,598,346 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6129,681,007 - 129,772,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,977,002 - 130,068,841 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06129,340,729 - 129,432,704 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06134,804,128 - 134,941,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6134,804,141 - 134,939,358 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,942,657 - 144,077,935 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,204,405 - 135,299,068 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6127,073,782 - 127,165,461 (+)NCBICelera
Cytogenetic Map6q32NCBI
Ppp2r5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555381,276,083 - 1,361,639 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555381,233,511 - 1,363,956 (+)NCBIChiLan1.0ChiLan1.0
PPP2R5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215102,915,190 - 103,081,747 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114102,131,645 - 102,298,187 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01482,383,086 - 82,549,822 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114102,206,546 - 102,372,978 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14102,206,396 - 102,372,978 (+)Ensemblpanpan1.1panPan2
PPP2R5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1869,846,311 - 69,969,409 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl869,846,446 - 69,967,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha869,361,349 - 69,484,545 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0870,124,041 - 70,247,431 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl870,123,944 - 70,247,431 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1869,788,763 - 69,911,878 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0869,854,037 - 69,977,442 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0870,253,916 - 70,377,552 (+)NCBIUU_Cfam_GSD_1.0
Ppp2r5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086404,003,425 - 4,141,415 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493683596,930 - 192,756 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493683554,478 - 192,486 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP2R5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12479,703,316 - 79,875,379 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2479,703,312 - 79,875,389 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605366,888,098 - 67,054,272 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp2r5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247342,335,243 - 2,470,811 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247342,337,649 - 2,471,319 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence



Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002540 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015007907 UniProtKB/TrEMBL
  ENSSSCG00025029875 UniProtKB/TrEMBL
  ENSSSCG00035055845 UniProtKB/TrEMBL
  ENSSSCG00040075784 UniProtKB/TrEMBL
  ENSSSCG00045024877 UniProtKB/TrEMBL
  ENSSSCG00050003070 UniProtKB/TrEMBL
  ENSSSCG00055019058 UniProtKB/TrEMBL
  ENSSSCG00060006718 UniProtKB/TrEMBL
  ENSSSCG00070010771 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000002821.4 UniProtKB/TrEMBL
  ENSSSCT00000039597.3 UniProtKB/TrEMBL
  ENSSSCT00000056383 ENTREZGENE
  ENSSSCT00000056383.3 UniProtKB/TrEMBL
  ENSSSCT00000078632.2 UniProtKB/TrEMBL
  ENSSSCT00000089627.2 UniProtKB/TrEMBL
  ENSSSCT00000093936.1 UniProtKB/TrEMBL
  ENSSSCT00000101475 ENTREZGENE
  ENSSSCT00000101475.1 UniProtKB/TrEMBL
  ENSSSCT00015010718.1 UniProtKB/TrEMBL
  ENSSSCT00015011414.1 UniProtKB/TrEMBL
  ENSSSCT00015011479.1 UniProtKB/TrEMBL
  ENSSSCT00025040636.1 UniProtKB/TrEMBL
  ENSSSCT00025040808.1 UniProtKB/TrEMBL
  ENSSSCT00035074604.1 UniProtKB/TrEMBL
  ENSSSCT00035074633.1 UniProtKB/TrEMBL
  ENSSSCT00035074644.1 UniProtKB/TrEMBL
  ENSSSCT00035074665.1 UniProtKB/TrEMBL
  ENSSSCT00040105288.1 UniProtKB/TrEMBL
  ENSSSCT00040105290.1 UniProtKB/TrEMBL
  ENSSSCT00040105297.1 UniProtKB/TrEMBL
  ENSSSCT00045042467.1 UniProtKB/TrEMBL
  ENSSSCT00045042708.1 UniProtKB/TrEMBL
  ENSSSCT00050004146.1 UniProtKB/TrEMBL
  ENSSSCT00055037820.1 UniProtKB/TrEMBL
  ENSSSCT00055038058.1 UniProtKB/TrEMBL
  ENSSSCT00055038204.1 UniProtKB/TrEMBL
  ENSSSCT00055038384.1 UniProtKB/TrEMBL
  ENSSSCT00055038525.1 UniProtKB/TrEMBL
  ENSSSCT00060008570.1 UniProtKB/TrEMBL
  ENSSSCT00060008579.1 UniProtKB/TrEMBL
  ENSSSCT00070020995.1 UniProtKB/TrEMBL
  ENSSSCT00070021019.1 UniProtKB/TrEMBL
  ENSSSCT00070021030.1 UniProtKB/TrEMBL
  ENSSSCT00070021038.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  PP2A_B56 UniProtKB/TrEMBL
NCBI Gene PPP2R5C ENTREZGENE
PANTHER PTHR10257 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM UniProtKB/TrEMBL
Pfam B56 UniProtKB/TrEMBL
PIRSF PP2A_B56 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A287A9P4_PIG UniProtKB/TrEMBL
  A0A287BKZ3 ENTREZGENE
  A0A480IVK4 ENTREZGENE, UniProtKB/TrEMBL
  A0A480SUS1 ENTREZGENE, UniProtKB/TrEMBL
  A0A480WSD5 ENTREZGENE, UniProtKB/TrEMBL
  A0A481B7C5 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TKK8_PIG UniProtKB/TrEMBL
  A0A4X1TMK8_PIG UniProtKB/TrEMBL
  A0A4X1TML9_PIG UniProtKB/TrEMBL
  A0A4X1TQ94_PIG UniProtKB/TrEMBL
  A0A5G2RCB5_PIG UniProtKB/TrEMBL
  A0A5G2RF70_PIG UniProtKB/TrEMBL
  A0A8D0J209 ENTREZGENE
  A0A8D0ML06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AKT5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1G9X4_PIG UniProtKB/TrEMBL
  A0A8D1R9V6_PIG UniProtKB/TrEMBL
  A0A8D1RB44 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SZ80_PIG UniProtKB/TrEMBL
  A0A8W4FB82_PIG UniProtKB/TrEMBL
  A0A8W4FP03_PIG UniProtKB/TrEMBL
  F1S9Y5_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287BKZ3 UniProtKB/TrEMBL
VGNC ID VGNC:91753 ENTREZGENE