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Gene: PPP2R5C (protein phosphatase 2 regulatory subunit B'gamma) Homo sapiens
Symbol: PPP2R5C
Name: protein phosphatase 2 regulatory subunit B'gamma
Description: Exhibits peptidase activity and protein phosphatase regulator activity. Involved in negative regulation of cell population proliferation; proteolysis; and signal transduction by p53 class mediator. Localizes to several cellular components, including Golgi apparatus; chromosome, centromeric region; and protein phosphatase type 2A complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B' alpha regulatory subunit; B56G; B56gamma; MGC23064; PP2A B subunit isoform B'-gamma; PP2A B subunit isoform B56-gamma; PP2A B subunit isoform PR61-gamma; PP2A B subunit isoform R5-gamma; PR61G; protein phosphatase 2, regulatory subunit B (B56), gamma isoform; protein phosphatase 2, regulatory subunit B', gamma isoform; renal carcinoma antigen NY-REN-29; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Related Pseudogenes: PPP2R5CP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl14101,761,798 - 101,927,989 (+)EnsemblGRCh38hg38GRCh38
GRCh3814101,760,573 - 101,927,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714102,226,910 - 102,394,329 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614101,345,925 - 101,463,831 (+)NCBINCBI36hg18NCBI36
Build 3414101,345,924 - 101,442,736NCBI
Celera1482,282,956 - 82,448,834 (+)NCBI
Cytogenetic Map14q32.31NCBI
HuRef1482,408,998 - 82,573,806 (+)NCBIHuRef
CHM1_114102,166,309 - 102,332,185 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PPP2R5C
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319620
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.