POLR1B (RNA polymerase I subunit B) - Rat Genome Database

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Gene: POLR1B (RNA polymerase I subunit B) Sus scrofa
Analyze
Symbol: POLR1B
Name: RNA polymerase I subunit B
RGD ID: 14241221
Description: ENCODES a protein that exhibits DNA-directed 5'-3' RNA polymerase activity (ortholog); INVOLVED IN embryo implantation (ortholog); nucleologenesis (ortholog); rRNA transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WITH Mandibulofacial Dysostosis (ortholog); Treacher Collins syndrome (ortholog); Treacher Collins syndrome 4 (ortholog); FOUND IN RNA polymerase I complex (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA-directed RNA polymerase I subunit RPA2; polymerase (RNA) I polypeptide B, 128kDa; RNA polymerase I polypeptide B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl343,950,002 - 43,975,683 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1343,949,032 - 43,974,283 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2345,544,060 - 45,568,445 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
POLR1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl343,950,002 - 43,975,683 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1343,949,032 - 43,974,283 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2345,544,060 - 45,568,445 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POLR1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382112,542,036 - 112,579,818 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2112,541,915 - 112,579,818 (+)EnsemblGRCh38hg38GRCh38
GRCh372113,299,613 - 113,337,395 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,016,084 - 113,051,879 (+)NCBINCBI36Build 36hg18NCBI36
Build 342113,015,843 - 113,051,639NCBI
Celera2106,685,049 - 106,720,277 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2105,754,007 - 105,789,231 (+)NCBIHuRef
CHM1_12113,303,652 - 113,338,870 (+)NCBICHM1_1
T2T-CHM13v2.02112,968,686 - 113,006,450 (+)NCBIT2T-CHM13v2.0
Polr1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392128,942,891 - 128,969,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2128,942,915 - 128,968,514 (+)EnsemblGRCm39 Ensembl
GRCm382129,100,970 - 129,128,060 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,100,995 - 129,126,594 (+)EnsemblGRCm38mm10GRCm38
MGSCv372128,926,732 - 128,952,331 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,792,479 - 128,818,036 (+)NCBIMGSCv36mm8
Celera2130,328,366 - 130,353,838 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.68NCBI
Polr1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83136,787,130 - 136,811,608 (+)NCBIGRCr8
mRatBN7.23116,333,910 - 116,358,385 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,333,889 - 116,358,379 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,231,013 - 120,255,438 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03128,826,598 - 128,851,016 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03126,487,078 - 126,511,500 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03121,632,043 - 121,656,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,632,043 - 121,656,506 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03128,358,264 - 128,382,727 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,706,483 - 116,730,946 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13116,612,055 - 116,636,519 (+)NCBI
Celera3115,159,305 - 115,183,765 (+)NCBICelera
Cytogenetic Map3q36NCBI
Polr1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,714,156 - 1,737,820 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,714,156 - 1,737,749 (-)NCBIChiLan1.0ChiLan1.0
POLR1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21215,545,294 - 15,588,412 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A15,548,058 - 15,584,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,478,133 - 89,516,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A113,555,452 - 113,590,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,555,452 - 113,590,377 (+)Ensemblpanpan1.1panPan2
POLR1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11736,774,472 - 36,798,900 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1736,774,541 - 36,797,525 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,543,712 - 36,568,761 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,550,047 - 37,575,002 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,545,667 - 37,575,002 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11736,688,159 - 36,713,214 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01736,742,224 - 36,767,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01736,956,099 - 36,980,996 (+)NCBIUU_Cfam_GSD_1.0
Polr1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,139,613 - 82,161,453 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367831,034,054 - 1,056,384 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367831,034,097 - 1,055,798 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLR1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11415,549,963 - 15,585,947 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1415,550,254 - 15,584,521 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660804,095,537 - 4,131,082 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Polr1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474912,602,004 - 12,625,200 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474912,602,078 - 12,625,200 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in POLR1B
478 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000008871   ⟹   ENSSSCP00000008645
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl343,950,171 - 43,974,005 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000047764   ⟹   ENSSSCP00000031743
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl343,950,002 - 43,973,981 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000048528   ⟹   ENSSSCP00000040694
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl343,950,181 - 43,975,683 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000072672   ⟹   ENSSSCP00000066078
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl343,950,181 - 43,975,683 (-)Ensembl
RefSeq Acc Id: XM_003124801   ⟹   XP_003124849
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1343,949,032 - 43,974,283 (-)NCBI
Sequence:
RefSeq Acc Id: XP_003124849   ⟸   XM_003124801
- UniProtKB: A0A480EKA2 (UniProtKB/TrEMBL),   A0A4X1V7F6 (UniProtKB/TrEMBL),   A0A8D0PIU7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000040694   ⟸   ENSSSCT00000048528
Ensembl Acc Id: ENSSSCP00000066078   ⟸   ENSSSCT00000072672
Ensembl Acc Id: ENSSSCP00000031743   ⟸   ENSSSCT00000047764
Ensembl Acc Id: ENSSSCP00000008645   ⟸   ENSSSCT00000008871
Protein Domains
DNA-directed RNA polymerase I subunit RPA2   DNA-directed RNA polymerase subunit 2 hybrid-   RNA polymerase beta subunit protrusion   RNA polymerase Rpb2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008098 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015063069 UniProtKB/TrEMBL
  ENSSSCG00025004108 UniProtKB/TrEMBL
  ENSSSCG00035023576 UniProtKB/TrEMBL
  ENSSSCG00045019929 UniProtKB/TrEMBL
  ENSSSCG00055005674 UniProtKB/TrEMBL
  ENSSSCG00060058714 UniProtKB/TrEMBL
  ENSSSCG00065062940 UniProtKB/TrEMBL
  ENSSSCG00070022086 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008871.5 UniProtKB/TrEMBL
  ENSSSCT00000047764.3 UniProtKB/TrEMBL
  ENSSSCT00000048528 ENTREZGENE
  ENSSSCT00000048528.2 UniProtKB/TrEMBL
  ENSSSCT00000072672.2 UniProtKB/TrEMBL
  ENSSSCT00015084757.1 UniProtKB/TrEMBL
  ENSSSCT00015085499.1 UniProtKB/TrEMBL
  ENSSSCT00015085681.1 UniProtKB/TrEMBL
  ENSSSCT00015085762.1 UniProtKB/TrEMBL
  ENSSSCT00025005478.1 UniProtKB/TrEMBL
  ENSSSCT00025005480.1 UniProtKB/TrEMBL
  ENSSSCT00025005491.1 UniProtKB/TrEMBL
  ENSSSCT00025005505.1 UniProtKB/TrEMBL
  ENSSSCT00035030914.1 UniProtKB/TrEMBL
  ENSSSCT00035030933.1 UniProtKB/TrEMBL
  ENSSSCT00035030938.1 UniProtKB/TrEMBL
  ENSSSCT00035030944.1 UniProtKB/TrEMBL
  ENSSSCT00035030945.1 UniProtKB/TrEMBL
  ENSSSCT00045034119.1 UniProtKB/TrEMBL
  ENSSSCT00045034239.1 UniProtKB/TrEMBL
  ENSSSCT00045034356.1 UniProtKB/TrEMBL
  ENSSSCT00045034468.1 UniProtKB/TrEMBL
  ENSSSCT00055011057.1 UniProtKB/TrEMBL
  ENSSSCT00055011198.1 UniProtKB/TrEMBL
  ENSSSCT00055011266.1 UniProtKB/TrEMBL
  ENSSSCT00055011343.1 UniProtKB/TrEMBL
  ENSSSCT00055011395.1 UniProtKB/TrEMBL
  ENSSSCT00060080110.1 UniProtKB/TrEMBL
  ENSSSCT00060080120.1 UniProtKB/TrEMBL
  ENSSSCT00060080131.1 UniProtKB/TrEMBL
  ENSSSCT00060080142.1 UniProtKB/TrEMBL
  ENSSSCT00065086344.1 UniProtKB/TrEMBL
  ENSSSCT00065086354.1 UniProtKB/TrEMBL
  ENSSSCT00065086360.1 UniProtKB/TrEMBL
  ENSSSCT00065086365.1 UniProtKB/TrEMBL
  ENSSSCT00070044118.1 UniProtKB/TrEMBL
  ENSSSCT00070044394.1 UniProtKB/TrEMBL
  ENSSSCT00070044464.1 UniProtKB/TrEMBL
  ENSSSCT00070044646.1 UniProtKB/TrEMBL
  ENSSSCT00070044713.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.270.10 UniProtKB/TrEMBL
  2.40.50.150 UniProtKB/TrEMBL
  3.90.1070.20 UniProtKB/TrEMBL
  3.90.1100.10 UniProtKB/TrEMBL
  3.90.1110.10 UniProtKB/TrEMBL
  RNA polymerase alpha subunit dimerisation domain UniProtKB/TrEMBL
InterPro DNA-dir_RNA_pol_su2 UniProtKB/TrEMBL
  DNA-dir_RNAP_su2_dom UniProtKB/TrEMBL
  DNA-dir_RNAP_su2_hyb_sf UniProtKB/TrEMBL
  RNA_pol_bsu_CS UniProtKB/TrEMBL
  RNA_pol_bsu_protrusion UniProtKB/TrEMBL
  RNA_pol_Rpb2_2 UniProtKB/TrEMBL
  RNA_pol_Rpb2_2_sf UniProtKB/TrEMBL
  RNA_pol_Rpb2_3 UniProtKB/TrEMBL
  RNA_pol_Rpb2_7 UniProtKB/TrEMBL
  RNA_pol_RPB2_OB-fold UniProtKB/TrEMBL
  Rpa2_dom_4 UniProtKB/TrEMBL
KEGG Report ssc:100517151 UniProtKB/TrEMBL
NCBI Gene POLR1B ENTREZGENE
PANTHER DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 UniProtKB/TrEMBL
  PTHR20856 UniProtKB/TrEMBL
Pfam RNA_pol_Rpa2_4 UniProtKB/TrEMBL
  RNA_pol_Rpb2_1 UniProtKB/TrEMBL
  RNA_pol_Rpb2_2 UniProtKB/TrEMBL
  RNA_pol_Rpb2_3 UniProtKB/TrEMBL
  RNA_pol_Rpb2_6 UniProtKB/TrEMBL
  RNA_pol_Rpb2_7 UniProtKB/TrEMBL
PROSITE RNA_POL_BETA UniProtKB/TrEMBL
Superfamily-SCOP beta and beta-prime subunits of DNA dependent RNA-polymerase UniProtKB/TrEMBL
UniProt A0A286ZJK9_PIG UniProtKB/TrEMBL
  A0A287A9S7_PIG UniProtKB/TrEMBL
  A0A480EKA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V4D4_PIG UniProtKB/TrEMBL
  A0A4X1V6W8_PIG UniProtKB/TrEMBL
  A0A4X1V7F6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1V7M1_PIG UniProtKB/TrEMBL
  A0A4X1V7P1_PIG UniProtKB/TrEMBL
  A0A5G2QVX3_PIG UniProtKB/TrEMBL
  A0A8D0PIU7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0PJG4_PIG UniProtKB/TrEMBL
  A0A8D1W4L1_PIG UniProtKB/TrEMBL
  A0A8D1W4V4_PIG UniProtKB/TrEMBL
  F1SUA2_PIG UniProtKB/TrEMBL
  H9LBW0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:91643 ENTREZGENE