POLR1B (RNA polymerase I subunit B) - Rat Genome Database

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Gene: POLR1B (RNA polymerase I subunit B) Pan paniscus
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Symbol: POLR1B
Name: RNA polymerase I subunit B
RGD ID: 11936102
Description: ENCODES a protein that exhibits DNA-directed 5'-3' RNA polymerase activity (ortholog); INVOLVED IN embryo implantation (ortholog); nucleologenesis (ortholog); rRNA transcription (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; ASSOCIATED WITH Mandibulofacial Dysostosis (ortholog); Treacher Collins syndrome (ortholog); Treacher Collins syndrome 4 (ortholog); FOUND IN RNA polymerase I complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DNA-directed RNA polymerase I subunit RPA2; polymerase (RNA) I polypeptide B, 128kDa
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21215,545,294 - 15,588,412 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A15,548,058 - 15,584,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,478,133 - 89,516,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A113,555,452 - 113,590,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,555,452 - 113,590,377 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
POLR1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21215,545,294 - 15,588,412 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A15,548,058 - 15,584,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,478,133 - 89,516,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A113,555,452 - 113,590,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,555,452 - 113,590,377 (+)Ensemblpanpan1.1panPan2
POLR1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382112,542,036 - 112,579,818 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2112,541,915 - 112,579,818 (+)EnsemblGRCh38hg38GRCh38
GRCh372113,299,613 - 113,337,395 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,016,084 - 113,051,879 (+)NCBINCBI36Build 36hg18NCBI36
Build 342113,015,843 - 113,051,639NCBI
Celera2106,685,049 - 106,720,277 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2105,754,007 - 105,789,231 (+)NCBIHuRef
CHM1_12113,303,652 - 113,338,870 (+)NCBICHM1_1
T2T-CHM13v2.02112,968,686 - 113,006,450 (+)NCBIT2T-CHM13v2.0
Polr1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392128,942,891 - 128,969,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2128,942,915 - 128,968,514 (+)EnsemblGRCm39 Ensembl
GRCm382129,100,970 - 129,128,060 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,100,995 - 129,126,594 (+)EnsemblGRCm38mm10GRCm38
MGSCv372128,926,732 - 128,952,331 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,792,479 - 128,818,036 (+)NCBIMGSCv36mm8
Celera2130,328,366 - 130,353,838 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.68NCBI
Polr1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83136,787,130 - 136,811,608 (+)NCBIGRCr8
mRatBN7.23116,333,910 - 116,358,385 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,333,889 - 116,358,379 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,231,013 - 120,255,438 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03128,826,598 - 128,851,016 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03126,487,078 - 126,511,500 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03121,632,043 - 121,656,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,632,043 - 121,656,506 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03128,358,264 - 128,382,727 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,706,483 - 116,730,946 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13116,612,055 - 116,636,519 (+)NCBI
Celera3115,159,305 - 115,183,765 (+)NCBICelera
Cytogenetic Map3q36NCBI
Polr1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,714,156 - 1,737,820 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,714,156 - 1,737,749 (-)NCBIChiLan1.0ChiLan1.0
POLR1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11736,774,472 - 36,798,900 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1736,774,541 - 36,797,525 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,543,712 - 36,568,761 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,550,047 - 37,575,002 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,545,667 - 37,575,002 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11736,688,159 - 36,713,214 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01736,742,224 - 36,767,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01736,956,099 - 36,980,996 (+)NCBIUU_Cfam_GSD_1.0
Polr1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,139,613 - 82,161,453 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367831,034,054 - 1,056,384 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367831,034,097 - 1,055,798 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLR1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl343,950,002 - 43,975,683 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1343,949,032 - 43,974,283 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2345,544,060 - 45,568,445 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POLR1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11415,549,963 - 15,585,947 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1415,550,254 - 15,584,521 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660804,095,537 - 4,131,082 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Polr1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474912,602,004 - 12,625,200 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474912,602,078 - 12,625,200 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000003742   ⟹   ENSPPAP00000000801
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A113,555,452 - 113,590,377 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000003840   ⟹   ENSPPAP00000000821
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A113,556,022 - 113,588,950 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000003856   ⟹   ENSPPAP00000000830
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A113,556,022 - 113,588,950 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000003885   ⟹   ENSPPAP00000000835
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A113,556,022 - 113,588,741 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000003891   ⟹   ENSPPAP00000000841
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A113,556,022 - 113,577,677 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000003895   ⟹   ENSPPAP00000000844
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A113,556,022 - 113,559,360 (+)Ensembl
RefSeq Acc Id: XM_055107406   ⟹   XP_054963381
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21215,545,294 - 15,588,412 (-)NCBI
NHGRI_mPanPan12A15,548,058 - 15,584,588 (-)NCBI
RefSeq Acc Id: XM_055107407   ⟹   XP_054963382
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21215,545,294 - 15,581,844 (-)NCBI
NHGRI_mPanPan12A15,548,058 - 15,584,608 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054963381 (Get FASTA)   NCBI Sequence Viewer  
  XP_054963382 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000000801.1
  ENSPPAP00000000821.1
  ENSPPAP00000000830.1
  ENSPPAP00000000835.1
  ENSPPAP00000000841.1
  ENSPPAP00000000844.1
Ensembl Acc Id: ENSPPAP00000000801   ⟸   ENSPPAT00000003742
Ensembl Acc Id: ENSPPAP00000000830   ⟸   ENSPPAT00000003856
Ensembl Acc Id: ENSPPAP00000000821   ⟸   ENSPPAT00000003840
Ensembl Acc Id: ENSPPAP00000000841   ⟸   ENSPPAT00000003891
Ensembl Acc Id: ENSPPAP00000000844   ⟸   ENSPPAT00000003895
Ensembl Acc Id: ENSPPAP00000000835   ⟸   ENSPPAT00000003885
RefSeq Acc Id: XP_054963382   ⟸   XM_055107407
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZDU5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054963381   ⟸   XM_055107406
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZDU5 (UniProtKB/TrEMBL)
Protein Domains
DNA-directed RNA polymerase I subunit RPA2   DNA-directed RNA polymerase subunit 2 hybrid-   RNA polymerase beta subunit protrusion   RNA polymerase Rpb2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000002774 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000003742.1 UniProtKB/TrEMBL
  ENSPPAT00000003840.1 UniProtKB/TrEMBL
  ENSPPAT00000003856.1 UniProtKB/TrEMBL
  ENSPPAT00000003885.1 UniProtKB/TrEMBL
  ENSPPAT00000003891.1 UniProtKB/TrEMBL
  ENSPPAT00000003895.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.270.10 UniProtKB/TrEMBL
  2.40.50.150 UniProtKB/TrEMBL
  3.90.1070.20 UniProtKB/TrEMBL
  3.90.1100.10 UniProtKB/TrEMBL
  3.90.1110.10 UniProtKB/TrEMBL
  RNA polymerase alpha subunit dimerisation domain UniProtKB/TrEMBL
InterPro DNA-dir_RNA_pol_su2 UniProtKB/TrEMBL
  DNA-dir_RNAP_su2_dom UniProtKB/TrEMBL
  DNA-dir_RNAP_su2_hyb_sf UniProtKB/TrEMBL
  RNA_pol_bsu_CS UniProtKB/TrEMBL
  RNA_pol_bsu_protrusion UniProtKB/TrEMBL
  RNA_pol_Rpb2_2 UniProtKB/TrEMBL
  RNA_pol_Rpb2_2_sf UniProtKB/TrEMBL
  RNA_pol_Rpb2_3 UniProtKB/TrEMBL
  RNA_pol_Rpb2_7 UniProtKB/TrEMBL
  RNA_pol_RPB2_OB-fold UniProtKB/TrEMBL
  Rpa2_dom_4 UniProtKB/TrEMBL
NCBI Gene POLR1B ENTREZGENE
PANTHER PTHR20856 UniProtKB/TrEMBL
Pfam RNA_pol_Rpa2_4 UniProtKB/TrEMBL
  RNA_pol_Rpb2_1 UniProtKB/TrEMBL
  RNA_pol_Rpb2_2 UniProtKB/TrEMBL
  RNA_pol_Rpb2_3 UniProtKB/TrEMBL
  RNA_pol_Rpb2_6 UniProtKB/TrEMBL
  RNA_pol_Rpb2_7 UniProtKB/TrEMBL
PROSITE RNA_POL_BETA UniProtKB/TrEMBL
Superfamily-SCOP beta and beta-prime subunits of DNA dependent RNA-polymerase UniProtKB/TrEMBL
UniProt A0A2R8Z7S8_PANPA UniProtKB/TrEMBL
  A0A2R8ZBE9_PANPA UniProtKB/TrEMBL
  A0A2R8ZBF4_PANPA UniProtKB/TrEMBL
  A0A2R8ZDU5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZDW2_PANPA UniProtKB/TrEMBL
  A0A2R8ZDY4_PANPA UniProtKB/TrEMBL