DGKD (diacylglycerol kinase delta) - Rat Genome Database

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Gene: DGKD (diacylglycerol kinase delta) Sus scrofa
Analyze
Symbol: DGKD
Name: diacylglycerol kinase delta
RGD ID: 14239718
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent diacylglycerol kinase activity (inferred); identical protein binding (inferred); INVOLVED IN diacylglycerol metabolic process (inferred); glycerolipid metabolic process (inferred); lipid metabolic process (inferred); ASSOCIATED WITH dilated cardiomyopathy (ortholog); Joubert syndrome 22 (ortholog); Lennox-Gastaut syndrome (ortholog); FOUND IN cytoplasmic vesicle (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: diacylglycerol kinase, delta 130kDa
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,749,345 - 133,867,801 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,749,349 - 133,867,804 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,864,561 - 147,920,469 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DGKD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15133,749,345 - 133,867,801 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115133,749,349 - 133,867,804 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215147,864,561 - 147,920,469 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DGKD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382233,354,494 - 233,472,098 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2233,354,494 - 233,472,104 (+)EnsemblGRCh38hg38GRCh38
GRCh372234,263,140 - 234,380,744 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362233,927,892 - 234,045,482 (+)NCBINCBI36Build 36hg18NCBI36
Build 342234,045,152 - 234,162,743NCBI
Celera2227,984,663 - 228,102,014 (+)NCBICelera
Cytogenetic Map2q37.1NCBI
HuRef2226,097,513 - 226,181,435 (+)NCBIHuRef
CHM1_12234,269,197 - 234,386,745 (+)NCBICHM1_1
T2T-CHM13v2.02233,842,577 - 233,960,616 (+)NCBIT2T-CHM13v2.0
Dgkd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39187,780,942 - 87,872,900 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl187,781,009 - 87,872,902 (+)EnsemblGRCm39 Ensembl
GRCm38187,853,264 - 87,945,177 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl187,853,287 - 87,945,180 (+)EnsemblGRCm38mm10GRCm38
MGSCv37189,749,862 - 89,841,064 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera190,838,152 - 90,902,542 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map144.44NCBI
Dgkd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8995,964,507 - 96,055,160 (+)NCBIGRCr8
mRatBN7.2988,516,686 - 88,607,349 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl988,516,715 - 88,607,345 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0994,980,328 - 95,071,531 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl994,980,409 - 95,069,714 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0994,730,771 - 94,790,639 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4986,836,919 - 86,895,274 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera986,109,371 - 86,169,037 (+)NCBICelera
Cytogenetic Map9q35NCBI
Dgkd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554532,742,842 - 2,835,811 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554532,740,922 - 2,802,669 (-)NCBIChiLan1.0ChiLan1.0
DGKD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213135,956,130 - 136,075,046 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B135,971,100 - 136,090,010 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B120,582,278 - 120,701,165 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B239,496,098 - 239,611,873 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B239,525,401 - 239,611,873 (+)Ensemblpanpan1.1panPan2
DGKD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12544,851,827 - 44,961,352 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2544,851,493 - 44,961,364 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2545,346,277 - 45,456,570 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02545,111,139 - 45,221,033 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2545,111,114 - 45,221,493 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12545,035,406 - 45,145,670 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02544,881,415 - 44,991,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02545,036,791 - 45,147,308 (+)NCBIUU_Cfam_GSD_1.0
Dgkd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303187,042,192 - 187,112,792 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365253,828,939 - 3,897,529 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365253,826,929 - 3,897,618 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DGKD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110119,390,217 - 119,509,148 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10119,390,330 - 119,511,134 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604079,989,364 - 80,113,656 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dgkd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248435,899,538 - 5,957,422 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248435,879,335 - 5,959,525 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DGKD
3883 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 10 4 3 4 2 22 2 3 3
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000010339   ⟹   ENSSSCP00000010071
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15133,749,356 - 133,867,801 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000017753   ⟹   ENSSSCP00000017272
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15133,749,356 - 133,867,802 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000042876   ⟹   ENSSSCP00000040004
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15133,749,344 - 133,867,802 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000043423   ⟹   ENSSSCP00000033458
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl15133,749,345 - 133,867,800 (+)Ensembl
RefSeq Acc Id: XM_021075022   ⟹   XP_020930681
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,821,104 - 133,867,804 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075023   ⟹   XP_020930682
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,749,349 - 133,867,804 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075024   ⟹   XP_020930683
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,821,102 - 133,867,804 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075026   ⟹   XP_020930685
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,784,835 - 133,867,804 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075027   ⟹   XP_020930686
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,804,229 - 133,867,804 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075028   ⟹   XP_020930687
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,791,128 - 133,867,804 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075029   ⟹   XP_020930688
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115133,805,632 - 133,867,804 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020930682   ⟸   XM_021075023
- Peptide Label: isoform X2
- UniProtKB: A0A4X1U371 (UniProtKB/TrEMBL),   F1RJ92 (UniProtKB/TrEMBL),   A0A480IRK6 (UniProtKB/TrEMBL),   A0A8D1TZF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020930685   ⟸   XM_021075026
- Peptide Label: isoform X4
- UniProtKB: A0A4X1U389 (UniProtKB/TrEMBL),   A0A8D1TZF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020930687   ⟸   XM_021075028
- Peptide Label: isoform X6
- UniProtKB: A0A480JY22 (UniProtKB/TrEMBL),   A0A480K0Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020930686   ⟸   XM_021075027
- Peptide Label: isoform X5
- UniProtKB: A0A480JY22 (UniProtKB/TrEMBL),   A0A480K0Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020930688   ⟸   XM_021075029
- Peptide Label: isoform X7
- UniProtKB: A0A480K1U5 (UniProtKB/TrEMBL),   A0A480JY22 (UniProtKB/TrEMBL),   A0A480K0Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020930683   ⟸   XM_021075024
- Peptide Label: isoform X3
- UniProtKB: A0A481BD87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020930681   ⟸   XM_021075022
- Peptide Label: isoform X1
- UniProtKB: A0A480JY22 (UniProtKB/TrEMBL),   A0A480K0Q8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010071   ⟸   ENSSSCT00000010339
RefSeq Acc Id: ENSSSCP00000017272   ⟸   ENSSSCT00000017753
RefSeq Acc Id: ENSSSCP00000040004   ⟸   ENSSSCT00000042876
RefSeq Acc Id: ENSSSCP00000033458   ⟸   ENSSSCT00000043423
Protein Domains
DAGKc   PH   Phorbol-ester/DAG-type   SAM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000009432 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025017223 UniProtKB/TrEMBL
  ENSSSCG00030045155 UniProtKB/TrEMBL
  ENSSSCG00035073989 UniProtKB/TrEMBL
  ENSSSCG00040009469 UniProtKB/TrEMBL
  ENSSSCG00045018379 UniProtKB/TrEMBL
  ENSSSCG00050048589 UniProtKB/TrEMBL
  ENSSSCG00055010002 UniProtKB/TrEMBL
  ENSSSCG00060075506 UniProtKB/TrEMBL
  ENSSSCG00070014226 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010339 ENTREZGENE
  ENSSSCT00000010339.5 UniProtKB/TrEMBL
  ENSSSCT00000043423.3 UniProtKB/TrEMBL
  ENSSSCT00025023280.1 UniProtKB/TrEMBL
  ENSSSCT00025023335.1 UniProtKB/TrEMBL
  ENSSSCT00025023403.1 UniProtKB/TrEMBL
  ENSSSCT00030063008.1 UniProtKB/TrEMBL
  ENSSSCT00030063052.1 UniProtKB/TrEMBL
  ENSSSCT00035100368.1 UniProtKB/TrEMBL
  ENSSSCT00035100412.1 UniProtKB/TrEMBL
  ENSSSCT00035100511.1 UniProtKB/TrEMBL
  ENSSSCT00040012268.1 UniProtKB/TrEMBL
  ENSSSCT00040012285.1 UniProtKB/TrEMBL
  ENSSSCT00045031297.1 UniProtKB/TrEMBL
  ENSSSCT00045031541.1 UniProtKB/TrEMBL
  ENSSSCT00045031839.1 UniProtKB/TrEMBL
  ENSSSCT00050066182.1 UniProtKB/TrEMBL
  ENSSSCT00050066192.1 UniProtKB/TrEMBL
  ENSSSCT00055019578.1 UniProtKB/TrEMBL
  ENSSSCT00060103391.1 UniProtKB/TrEMBL
  ENSSSCT00060103658.1 UniProtKB/TrEMBL
  ENSSSCT00070027922.1 UniProtKB/TrEMBL
  ENSSSCT00070027941.1 UniProtKB/TrEMBL
  ENSSSCT00070027947.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.60.200.40 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro ATP-NAD_kinase_N UniProtKB/TrEMBL
  C1-like_sf UniProtKB/TrEMBL
  C1_DGKdelta_rpt1 UniProtKB/TrEMBL
  C1_DGKdelta_rpt2 UniProtKB/TrEMBL
  DGK UniProtKB/TrEMBL
  DGK-delta_SAM UniProtKB/TrEMBL
  Diacylglycerol_kin_accessory UniProtKB/TrEMBL
  Diacylglycerol_kinase_cat_dom UniProtKB/TrEMBL
  NAD/diacylglycerol_kinase_sf UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
NCBI Gene DGKD ENTREZGENE
PANTHER DIACYLGLYCEROL KINASE DELTA UniProtKB/TrEMBL
  PTHR11255 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  DAGK_acc UniProtKB/TrEMBL
  DAGK_cat UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  SAM_2 UniProtKB/TrEMBL
PROSITE DAGK UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART DAGKa UniProtKB/TrEMBL
  DAGKc UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF111331 UniProtKB/TrEMBL
  SSF47769 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A286ZPS1_PIG UniProtKB/TrEMBL
  A0A480IRK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A480JY22 ENTREZGENE, UniProtKB/TrEMBL
  A0A480K0Q8 ENTREZGENE, UniProtKB/TrEMBL
  A0A480K1U5 ENTREZGENE, UniProtKB/TrEMBL
  A0A481BD87 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U371 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U389 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U5C4_PIG UniProtKB/TrEMBL
  A0A8D1B541_PIG UniProtKB/TrEMBL
  A0A8D1DBQ5_PIG UniProtKB/TrEMBL
  A0A8D1TZF2 ENTREZGENE, UniProtKB/TrEMBL
  F1RJ92 ENTREZGENE
UniProt Secondary F1RJ92 UniProtKB/TrEMBL
VGNC ID VGNC:96180 ENTREZGENE