QSOX1 (quiescin sulfhydryl oxidase 1) - Rat Genome Database

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Gene: QSOX1 (quiescin sulfhydryl oxidase 1) Sus scrofa
Analyze
Symbol: QSOX1
Name: quiescin sulfhydryl oxidase 1
RGD ID: 14211106
Description: ENCODES a protein that exhibits FAD binding (inferred); flavin-dependent sulfhydryl oxidase activity (inferred); oxidoreductase activity (inferred); INVOLVED IN extracellular matrix assembly (inferred); negative regulation of macroautophagy (inferred); protein folding (inferred); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); autosomal recessive chronic granulomatous disease 2 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN extracellular exosome (inferred); extracellular space (inferred); Golgi apparatus (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: quiescin Q6 sulfhydryl oxidase 1; sulfhydryl oxidase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9121,779,792 - 121,822,825 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19121,779,072 - 121,822,829 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29133,595,396 - 133,638,610 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
QSOX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9121,779,792 - 121,822,825 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19121,779,072 - 121,822,829 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29133,595,396 - 133,638,610 (+)NCBISscrofa10.2Sscrofa10.2susScr3
QSOX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381180,154,869 - 180,204,030 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1180,154,869 - 180,204,030 (+)EnsemblGRCh38hg38GRCh38
GRCh371180,124,004 - 180,173,165 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361178,390,591 - 178,433,792 (+)NCBINCBI36Build 36hg18NCBI36
Build 341176,855,624 - 176,898,826NCBI
Celera1153,231,536 - 153,274,744 (+)NCBICelera
Cytogenetic Map1q25.2NCBI
HuRef1151,355,443 - 151,398,518 (+)NCBIHuRef
CHM1_11181,547,697 - 181,590,889 (+)NCBICHM1_1
T2T-CHM13v2.01179,510,604 - 179,559,769 (+)NCBIT2T-CHM13v2.0
Qsox1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391155,653,901 - 155,688,645 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1155,651,775 - 155,688,635 (-)EnsemblGRCm39 Ensembl
GRCm381155,778,155 - 155,812,899 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1155,776,029 - 155,812,889 (-)EnsemblGRCm38mm10GRCm38
MGSCv371157,625,285 - 157,660,029 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361157,540,373 - 157,575,117 (-)NCBIMGSCv36mm8
Celera1158,211,715 - 158,246,555 (-)NCBICelera
Cytogenetic Map1G3NCBI
cM Map167.64NCBI
Qsox1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81370,500,060 - 70,537,711 (-)NCBIGRCr8
mRatBN7.21367,949,780 - 67,987,434 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1367,949,780 - 67,987,459 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1370,529,544 - 70,566,399 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01371,844,987 - 71,881,834 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01369,106,470 - 69,143,317 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01373,423,396 - 73,460,890 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1373,423,397 - 73,460,935 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01378,351,222 - 78,388,703 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41370,739,793 - 70,777,526 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11370,753,873 - 70,791,628 (-)NCBI
Celera1367,815,702 - 67,852,956 (-)NCBICelera
Cytogenetic Map13q21NCBI
Qsox1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540619,363,938 - 19,402,134 (+)NCBIChiLan1.0ChiLan1.0
QSOX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2169,563,559 - 69,606,794 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1169,221,823 - 69,265,043 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01155,641,793 - 155,687,231 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11159,289,932 - 159,358,675 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1159,313,245 - 159,358,672 (+)Ensemblpanpan1.1panPan2
QSOX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1713,718,799 - 13,754,115 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl713,718,799 - 13,754,114 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha713,297,965 - 13,333,390 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0713,446,573 - 13,482,007 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl713,446,567 - 13,482,619 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1713,357,448 - 13,392,875 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0713,463,885 - 13,499,332 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0713,588,279 - 13,623,755 (+)NCBIUU_Cfam_GSD_1.0
Qsox1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934491,129,070 - 91,166,948 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364818,975,790 - 9,013,723 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364818,975,818 - 9,013,684 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
QSOX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12549,180,365 - 49,223,814 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2549,181,365 - 49,223,741 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605550,571,837 - 50,617,458 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Qsox1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624771449,992 - 489,693 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624771449,761 - 490,372 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in QSOX1
1845 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 6 3 3 1
Low 4 4 5 2 20 2 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016924   ⟹   ENSSSCP00000016471
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9121,779,800 - 121,822,825 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000070443   ⟹   ENSSSCP00000069728
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9121,779,800 - 121,822,825 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000074953   ⟹   ENSSSCP00000066335
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9121,779,792 - 121,822,047 (+)Ensembl
RefSeq Acc Id: XM_013989655   ⟹   XP_013845109
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19121,779,072 - 121,822,829 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013845109   ⟸   XM_013989655
- UniProtKB: A0A8D1X3F0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000016471   ⟸   ENSSSCT00000016924
RefSeq Acc Id: ENSSSCP00000066335   ⟸   ENSSSCT00000074953
RefSeq Acc Id: ENSSSCP00000069728   ⟸   ENSSSCT00000070443
Protein Domains
ERV/ALR sulfhydryl oxidase   Thioredoxin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015535 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015026323 UniProtKB/TrEMBL
  ENSSSCG00025044400 UniProtKB/TrEMBL
  ENSSSCG00035018734 UniProtKB/TrEMBL
  ENSSSCG00065000717 UniProtKB/TrEMBL
  ENSSSCG00070014108 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016924 ENTREZGENE
  ENSSSCT00000016924.5 UniProtKB/TrEMBL
  ENSSSCT00000070443.2 UniProtKB/TrEMBL
  ENSSSCT00000074953.2 UniProtKB/TrEMBL
  ENSSSCT00015034948.1 UniProtKB/TrEMBL
  ENSSSCT00015035010.1 UniProtKB/TrEMBL
  ENSSSCT00015035089.1 UniProtKB/TrEMBL
  ENSSSCT00015035193.1 UniProtKB/TrEMBL
  ENSSSCT00025060275.1 UniProtKB/TrEMBL
  ENSSSCT00025060519.1 UniProtKB/TrEMBL
  ENSSSCT00025060724.1 UniProtKB/TrEMBL
  ENSSSCT00035024222.1 UniProtKB/TrEMBL
  ENSSSCT00035024227.1 UniProtKB/TrEMBL
  ENSSSCT00065000848.1 UniProtKB/TrEMBL
  ENSSSCT00065000858.1 UniProtKB/TrEMBL
  ENSSSCT00065000863.1 UniProtKB/TrEMBL
  ENSSSCT00070027660.1 UniProtKB/TrEMBL
  ENSSSCT00070027668.1 UniProtKB/TrEMBL
  ENSSSCT00070027677.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1960 UniProtKB/TrEMBL
  1.20.120.310 UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/TrEMBL
InterPro ERV/ALR_sulphydryl_oxid_sf UniProtKB/TrEMBL
  ERV/ALR_sulphydryl_oxidase UniProtKB/TrEMBL
  QSOX_FAD-bd_dom UniProtKB/TrEMBL
  QSOX_FAD-bd_sf UniProtKB/TrEMBL
  QSOX_Trx1 UniProtKB/TrEMBL
  Sulfhydryl_oxidase UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
NCBI Gene QSOX1 ENTREZGENE
PANTHER PTHR22897 UniProtKB/TrEMBL
  SULFHYDRYL OXIDASE 1 UniProtKB/TrEMBL
Pfam Evr1_Alr UniProtKB/TrEMBL
  FAD_SOX UniProtKB/TrEMBL
  QSOX_Trx1 UniProtKB/TrEMBL
  Thioredoxin UniProtKB/TrEMBL
PROSITE ERV_ALR UniProtKB/TrEMBL
  THIOREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
  SSF69000 UniProtKB/TrEMBL
UniProt A0A4X1TZX3_PIG UniProtKB/TrEMBL
  A0A4X1U4T6_PIG UniProtKB/TrEMBL
  A0A4X1U5C5_PIG UniProtKB/TrEMBL
  A0A5G2QNR8_PIG UniProtKB/TrEMBL
  A0A5G2QXX3_PIG UniProtKB/TrEMBL
  A0A8D0N5U5_PIG UniProtKB/TrEMBL
  A0A8D0N7H2_PIG UniProtKB/TrEMBL
  A0A8D0NAG0_PIG UniProtKB/TrEMBL
  A0A8D0NB15_PIG UniProtKB/TrEMBL
  A0A8D1X3F0 ENTREZGENE, UniProtKB/TrEMBL
  F1S682_PIG UniProtKB/TrEMBL
VGNC ID VGNC:92033 ENTREZGENE