UGDH (UDP-glucose 6-dehydrogenase) - Rat Genome Database

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Gene: UGDH (UDP-glucose 6-dehydrogenase) Sus scrofa
Analyze
Symbol: UGDH
Name: UDP-glucose 6-dehydrogenase
RGD ID: 14182005
Description: ENCODES a protein that exhibits UDP-glucose 6-dehydrogenase activity (ortholog); INVOLVED IN gastrulation with mouth forming second (ortholog); PARTICIPATES IN congenital sucrase-isomaltase deficiency pathway; galactokinase deficiency pathway; GALE deficiency pathway; ASSOCIATED WITH developmental and epileptic encephalopathy 84 (ortholog); Generalized Epilepsy (ortholog); genetic disease (ortholog); FOUND IN nucleoplasm (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,725,288 - 30,759,326 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1830,725,281 - 30,759,359 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2832,340,313 - 32,374,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IBA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UGDH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl830,725,288 - 30,759,326 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1830,725,281 - 30,759,359 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2832,340,313 - 32,374,310 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UGDH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38439,498,755 - 39,527,439 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl439,498,755 - 39,528,311 (-)EnsemblGRCh38hg38GRCh38
GRCh37439,500,375 - 39,529,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36439,176,770 - 39,205,606 (-)NCBINCBI36Build 36hg18NCBI36
Build 34439,322,945 - 39,351,539NCBI
Celera439,938,164 - 39,967,004 (-)NCBICelera
Cytogenetic Map4p14NCBI
HuRef438,825,375 - 38,854,230 (-)NCBIHuRef
CHM1_1439,499,802 - 39,528,655 (-)NCBICHM1_1
T2T-CHM13v2.0439,468,409 - 39,497,229 (-)NCBIT2T-CHM13v2.0
Ugdh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39565,570,550 - 65,593,185 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl565,570,564 - 65,593,292 (-)EnsemblGRCm39 Ensembl
GRCm38565,413,207 - 65,435,842 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl565,413,221 - 65,435,949 (-)EnsemblGRCm38mm10GRCm38
MGSCv37565,804,460 - 65,827,081 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36565,692,356 - 65,714,977 (-)NCBIMGSCv36mm8
Celera562,689,905 - 62,712,959 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.67NCBI
Ugdh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81443,202,480 - 43,226,002 (+)NCBIGRCr8
mRatBN7.21442,848,704 - 42,872,351 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,848,854 - 42,872,354 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1443,202,670 - 43,226,148 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01444,502,588 - 44,526,066 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,982,708 - 43,006,181 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01444,479,614 - 44,502,845 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1444,479,614 - 44,502,845 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01444,299,226 - 44,322,226 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,542,781 - 45,570,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11445,545,171 - 45,573,352 (+)NCBI
Celera1441,999,555 - 42,023,022 (+)NCBICelera
Cytogenetic Map14p11NCBI
Ugdh
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,868,893 - 7,882,129 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,868,893 - 7,882,136 (+)NCBIChiLan1.0ChiLan1.0
UGDH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2339,688,142 - 39,716,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1439,880,751 - 39,909,008 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0433,827,532 - 33,856,204 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1439,679,915 - 39,708,215 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl439,681,300 - 39,708,215 (-)Ensemblpanpan1.1panPan2
UGDH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1372,935,532 - 72,964,151 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl372,839,920 - 72,963,208 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha375,481,824 - 75,511,112 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0373,708,348 - 73,737,653 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl373,553,586 - 73,737,645 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1372,974,965 - 73,004,279 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0373,121,242 - 73,150,553 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0373,507,747 - 73,537,066 (+)NCBIUU_Cfam_GSD_1.0
Ugdh
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528539,179,915 - 39,207,994 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364827,089,621 - 7,118,284 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364827,090,241 - 7,118,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UGDH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12710,781,324 - 10,810,595 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2710,781,502 - 10,810,817 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604757,174,192 - 57,202,679 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ugdh
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248704,782,252 - 4,799,703 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248704,768,307 - 4,801,333 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in UGDH
1171 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000026582   ⟹   ENSSSCP00000023928
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl830,725,288 - 30,759,326 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000086541   ⟹   ENSSSCP00000060029
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl830,725,288 - 30,759,326 (-)Ensembl
RefSeq Acc Id: XM_003356899   ⟹   XP_003356947
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1830,725,281 - 30,759,359 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013978599   ⟹   XP_013834053
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1830,725,283 - 30,759,314 (-)NCBI
Sequence:
RefSeq Acc Id: XP_003356947   ⟸   XM_003356899
- UniProtKB: I3LIM2 (UniProtKB/TrEMBL),   A0A8D1VHY8 (UniProtKB/TrEMBL),   A0A8D0LDX8 (UniProtKB/TrEMBL),   A0A8D1M1K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834053   ⟸   XM_013978599
- UniProtKB: I3LIM2 (UniProtKB/TrEMBL),   A0A8D1VHY8 (UniProtKB/TrEMBL),   A0A8D0LDX8 (UniProtKB/TrEMBL),   A0A8D1M1K8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000023928   ⟸   ENSSSCT00000026582
Ensembl Acc Id: ENSSSCP00000060029   ⟸   ENSSSCT00000086541

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000030150 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005003130 UniProtKB/TrEMBL
  ENSSSCG00015039474 UniProtKB/TrEMBL
  ENSSSCG00025070467 UniProtKB/TrEMBL
  ENSSSCG00030022347 UniProtKB/TrEMBL
  ENSSSCG00035002972 UniProtKB/TrEMBL
  ENSSSCG00040017141 UniProtKB/TrEMBL
  ENSSSCG00045024537 UniProtKB/TrEMBL
  ENSSSCG00050028945 UniProtKB/TrEMBL
  ENSSSCG00055019331 UniProtKB/TrEMBL
  ENSSSCG00060043321 UniProtKB/TrEMBL
  ENSSSCG00065000962 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000026582 ENTREZGENE
  ENSSSCT00000026582.3 UniProtKB/TrEMBL
  ENSSSCT00000086541.1 UniProtKB/TrEMBL
  ENSSSCT00005004773.1 UniProtKB/TrEMBL
  ENSSSCT00005004794.1 UniProtKB/TrEMBL
  ENSSSCT00015052588.1 UniProtKB/TrEMBL
  ENSSSCT00025096754.1 UniProtKB/TrEMBL
  ENSSSCT00030031046.1 UniProtKB/TrEMBL
  ENSSSCT00035003687.1 UniProtKB/TrEMBL
  ENSSSCT00040023092.1 UniProtKB/TrEMBL
  ENSSSCT00045041905.1 UniProtKB/TrEMBL
  ENSSSCT00050038902.1 UniProtKB/TrEMBL
  ENSSSCT00055037846.1 UniProtKB/TrEMBL
  ENSSSCT00060058754.1 UniProtKB/TrEMBL
  ENSSSCT00065001155.1 UniProtKB/TrEMBL
Gene3D-CATH Cytochrome c1, transmembrane anchor, C-terminal UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  UDP-Glc/GDP-Man UniProtKB/TrEMBL
  UDP-Glc/GDP-Man_DH_C UniProtKB/TrEMBL
  UDP-Glc/GDP-Man_DH_C_sf UniProtKB/TrEMBL
  UDP-Glc/GDP-Man_DH_dimer UniProtKB/TrEMBL
  UDP-Glc/GDP-Man_DH_N UniProtKB/TrEMBL
  UDPglc_DH_euk UniProtKB/TrEMBL
KEGG Report ssc:100627727 UniProtKB/TrEMBL
NCBI Gene UGDH ENTREZGENE
PANTHER PTHR11374 UniProtKB/TrEMBL
  UDP-GLUCOSE 6-DEHYDROGENASE UniProtKB/TrEMBL
Pfam UDPG_MGDP_dh UniProtKB/TrEMBL
  UDPG_MGDP_dh_C UniProtKB/TrEMBL
  UDPG_MGDP_dh_N UniProtKB/TrEMBL
PIRSF UDPglc_DH_euk UniProtKB/TrEMBL
  UDPglc_GDPman_dh UniProtKB/TrEMBL
SMART UDPG_MGDP_dh_C UniProtKB/TrEMBL
Superfamily-SCOP SSF48179 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
  SSF52413 UniProtKB/TrEMBL
UniProt A0A5G2Q7H2_PIG UniProtKB/TrEMBL
  A0A8D0LDX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1M1K8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1VHY8 ENTREZGENE
  I3LIM2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A8D1VHY8 UniProtKB/TrEMBL
VGNC ID VGNC:94686 ENTREZGENE