RAD21L1 (RAD21 cohesin complex component like 1)

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Gene: RAD21L1 (RAD21 cohesin complex component like 1) Sus scrofa

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Symbol:

RAD21L1

Name:

RAD21 cohesin complex component like 1

RGD ID:

14180324

Description:

INVOLVED IN double-strand break repair (ortholog); double-strand break repair via homologous recombination (ortholog); fertilization (ortholog); ASSOCIATED WITH spermatogenic failure 3 (ortholog); FOUND IN condensed nuclear chromosome (ortholog); lateral element (ortholog); meiotic cohesin complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

double-strand-break repair protein rad21-like protein 1; RAD21-like 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	17	34,035,526 - 34,064,215 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	38,591,104 - 38,611,242 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

spermatogenic failure 3 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromosome segregation (IEA)

double-strand break repair (ISO)

double-strand break repair via homologous recombination (ISO)

fertilization (ISO)

homologous chromosome pairing at meiosis (ISO)

meiotic attachment of telomere to nuclear envelope (ISO)

seminiferous tubule development (ISO)

sister chromatid cohesion (IEA)

spermatogenesis (ISO)

synaptonemal complex assembly (ISO)

Cellular Component

chromosome (IEA)

cohesin complex (IEA)

condensed nuclear chromosome (ISO)

lateral element (ISO)

meiotic cohesin complex (ISO)

nucleus (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RAD21L1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	17	34,035,526 - 34,064,215 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	38,591,104 - 38,611,242 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAD21L1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	1,226,044 - 1,255,876 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	1,226,044 - 1,296,421 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	1,206,688 - 1,236,520 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	1,154,700 - 1,183,101 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	20	1,303,090 - 1,331,471 (+)	NCBI		Celera
Cytogenetic Map	20	p13	NCBI
HuRef	20	1,161,202 - 1,187,291 (+)	NCBI		HuRef
CHM1_1	20	1,206,765 - 1,235,147 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	1,273,334 - 1,303,183 (+)	NCBI		T2T-CHM13v2.0

Rad21l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	151,486,286 - 151,512,542 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	151,487,324 - 151,510,453 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	151,644,366 - 151,670,622 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	151,645,404 - 151,668,533 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	151,471,140 - 151,494,269 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	151,336,845 - 151,359,974 (-)	NCBI		MGSCv36	mm8
Celera	2	157,462,516 - 157,485,682 (-)	NCBI		Celera
Cytogenetic Map	2	G3	NCBI
cM Map	2	74.83	NCBI

Rad21l1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	160,620,500 - 160,648,716 (-)	NCBI		GRCr8
mRatBN7.2	3	140,160,128 - 140,188,324 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	140,160,118 - 140,188,298 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	3	147,163,335 - 147,191,008 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	147,163,838 - 147,188,929 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	153,516,755 - 153,544,210 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	3	138,919,326 - 138,946,960 (-)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

Rad21l1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955596	457,835 - 486,046 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955596	455,932 - 485,853 (+)	NCBI	ChiLan1.0	ChiLan1.0

RAD21L1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	2,263,920 - 2,296,123 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	2,260,749 - 2,292,952 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	1,385,935 - 1,413,301 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	1,153,378 - 1,179,801 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	1,153,384 - 1,231,383 (+)	Ensembl	panpan1.1		panPan2

RAD21L1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	19,741,398 - 19,771,675 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	19,699,792 - 19,771,679 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	19,395,679 - 19,425,941 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	20,431,965 - 20,462,227 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	20,387,160 - 20,462,205 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	19,709,731 - 19,739,954 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	19,815,102 - 19,845,324 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	20,246,438 - 20,276,321 (-)	NCBI		UU_Cfam_GSD_1.0

Rad21l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	168,981,343 - 169,006,392 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	17,413,006 - 17,435,951 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	17,413,006 - 17,435,951 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAD21L1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	55,299,061 - 55,335,200 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	55,307,711 - 55,333,874 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666087	1,712,827 - 1,741,923 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rad21l1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	2,485,471 - 2,542,500 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	2,486,612 - 2,542,452 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RAD21L1
980 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021077689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU638675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP236274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021077689 ⟹ XP_020933348

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	17	34,035,526 - 34,064,215 (-)	NCBI

Sequence:

show sequence

AAAAACTACTGAGGAATACAGGCAGCATGTTCTACACACATGTGCTTATGAGTAAGCGAGGGCC
ATTGGCCAAAATCTGGCTTGCAGCTCACTGGGAGAAGAAACTCACTAAGGCCCATGTATTTGAG
TGTAATCTAGAGATAACCATTGAAAAAATTCTTTCACCTAAGGTGAAAATTGCACTTCGAACTT
CAGGACACCTTNCTTTGGGAGTTGTTCGAATCTATAATAGGAAGGCAAAATATCTTTTGGCAGA
TTGCAGTGAAGCATTGCTTAAATGAAGATGACATTTCGCCCAGGGGATGGTTGACCTTCCAAAA
GAAGTTTTGAAGCACTACACTGTATCACTTGCCAGAAAATTTCATGATTTTGACACCCAGAATA
TGAATGCTATTGATATTTCAGAACACTTTACTCAGAACCAAAGCAAACCAGAAGAAATCACACT
TAAAGAAGATTTTGGCAATGATCTACTTTTCCAAGCTGGGAGCTTTGGGGAGGAAGCCGAAATC
CTTAGAAGACATAGCTTCTTTGATGACAACATATTGCTGAATTCCAGTGGTCCTTTAGTTGAAC
ATAGTTCTGGAAGCCTCACTGGAGAANAATCTCTGTTTTATGACAGTGGAGATGGATTTGGAGA
TGAAGGGGCTGCAGGAGAAATGATTTTTTTTAGAGAGGAAGGAGTGAGACAATCTGTGCAAGAT
GATCCAAATATCCCTAGAAACATGCATTTGAATAAAATTTCCCTGCCTCTGAGCCCCAATACAT
AGGTAGAATCAGATAATCCGGAGTGTATATGCCCACCTGAAAATGAAAAAATGGATGAAACCAC
ATTATCAAATGAAGAGGAAGATNNTTACCTTGAGCCAATTGATACTTCAGATATTGCTGAAAAA
AGAAAAGGCAAAAAGAGGAAATTGCTCATAGATCCAGTCAAGGAGATCAGTAGCAAAATTATGC
ATAGACAGCTTACTTCCTTTACGGACACACTCATGGTTTTGGAACTTGCACCTCCTACCCAAAG
ACTGATGATGTGGAAGAAGAAGGGAGGAGCAGATACACTTCTGTCAACTGCTGCCCAGGATTTG
ATTCATGCCGAACTAAAAGTGTTGTTTACAAAATGCTTTTTGTCCTCTGGCTTTAAACTTGGAA
GAAAATTGATGCAGAAGAAGTCAGAAAGGGAAGAAATAGGAAATGAAAACATCGTAGAGACCTC
CATGATGAAAGGGTCAAATTCCCTGGAAGAGTTAAGTCAATCCTCAACTTGGAAGGAAGAAATT
GATGGATCTAAGTGTAGCTTTAACAAGGATACCAATAAAAATATTAACTCCGATCAGGATATTG
TTGAAATGGTCTCTTCAACTGCGGAGGAATCGTCTTTAATGAATGCCACCCTGGCAGAAGAAGT
TGAAAACTGTCTAACTGAATTGGAGTCATTGGGGAATGAACAAAATATTGAGGCAGAGAGATGG
AATCGAAGAATACTTCAAATGTTAAACAGATTGCGGGAATCTAACAAGATGGGAATGCAGTACT
TTAGTCTGATGAAGCTCTGCAGAAATAGTGACCGAAAACATGCTGCTGCCAAATTTTATAGCTT
TCTTGTCCTAAAAAAACAGCGGGCTATTGAGCTGAGTCAGAGTGCTCCCTATGCCGATATCATA
GCTACAGTGGGACCAATGTTCCATAAAATGTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020933348	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00035016072.1
	ENSSSCP00065031933.1

RefSeq Acc Id:

XP_020933348 ⟸ XM_021077689

- UniProtKB:

A0A8D1Z9P4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIEKILSPKVKIALRTSGHLXLGVV
RIYNRKAKYLLADCSEALLKXRXHFAQGMVDLPKEVLKHYTVSLARKFHDFDTQNMNAIDISEH
FTQNQSKPEEITLKEDFGNDLLFQAGSFGEEAEILRRHSFFDDNILLNSSGPLVEHSSGSLTGE
XSLFYDSGDGFGDEGAAGEMIFFREEGVRQSVQDDPNIPRNMHLNKISLPLSPNTXVESDNPEC
ICPPENEKMDETTLSNEEEDXYLEPIDTSDIAEKRKGKKRKLLIDPVKEISSKIMHRQLTSFTD
TLMVLELAPPTQRLMMWKKKGGADTLLSTAAQDLIHAELKVLFTKCFLSSGFKLGRKLMQKKSE
REEIGNENIVETSMMKGSNSLEELSQSSTWKEEIDGSKCSFNKDTNKNINSDQDIVEMVSSTAE
ESSLMNATLAEEVENCLTELESLGNEQNIEAERWNRRILQMLNRLRESNKMGMQYFSLMKLCRN
SDRKHAAAKFYSFLVLKKQRAIELSQSAPYADIIATVGPMFHKM

hide sequence

Protein Domains

Rad21/Rec8-like protein C-terminal eukaryotic Rad21/Rec8-like protein N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00035030309	UniProtKB/TrEMBL
	ENSSSCG00065053490	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00035040171.1	UniProtKB/TrEMBL
	ENSSSCT00065073302.1	UniProtKB/TrEMBL
Gene3D-CATH	Structural maintenance of chromosome 1. Chain E	UniProtKB/TrEMBL
InterPro	NXP1_M-like	UniProtKB/TrEMBL
	Rad21/Rec8-like	UniProtKB/TrEMBL
	Rad21/Rec8_C_eu	UniProtKB/TrEMBL
	Rad21_Rec8_N	UniProtKB/TrEMBL
	ScpA-like_C	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	RAD21L1	ENTREZGENE
PANTHER	DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21-LIKE PROTEIN 1	UniProtKB/TrEMBL
	SCC1 / RAD21 FAMILY MEMBER	UniProtKB/TrEMBL
Pfam	Rad21_Rec8	UniProtKB/TrEMBL
	Rad21_Rec8_N	UniProtKB/TrEMBL
Superfamily-SCOP	Winged helix' DNA-binding domain	UniProtKB/TrEMBL
UniProt	A0A8D1Z9P4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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