SYT3 (synaptotagmin 3) - Rat Genome Database

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Gene: SYT3 (synaptotagmin 3) Sus scrofa
Analyze
Symbol: SYT3
Name: synaptotagmin 3
RGD ID: 14177069
Description: ENCODES a protein that exhibits calcium-dependent phospholipid binding (ortholog); identical protein binding (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN positive regulation of vesicle fusion (ortholog); regulation of postsynaptic membrane neurotransmitter receptor levels (ortholog); response to calcium ion (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN postsynapse (ortholog); synaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: synaptotagmin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl655,417,951 - 55,434,175 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1655,417,949 - 55,449,322 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,316,981 - 51,336,155 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SYT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl655,417,951 - 55,434,175 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1655,417,949 - 55,449,322 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,316,981 - 51,336,155 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SYT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381950,621,977 - 50,658,105 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1950,621,307 - 50,639,881 (-)EnsemblGRCh38hg38GRCh38
GRCh371951,125,234 - 51,143,138 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,817,046 - 55,833,114 (-)NCBINCBI36Build 36hg18NCBI36
Build 341955,817,047 - 55,833,114NCBI
Celera1948,176,610 - 48,194,391 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1947,460,206 - 47,478,096 (-)NCBIHuRef
CHM1_11951,127,112 - 51,144,886 (-)NCBICHM1_1
T2T-CHM13v2.01953,710,730 - 53,746,830 (-)NCBIT2T-CHM13v2.0
Syt3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,032,197 - 44,049,454 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,033,526 - 44,049,611 (+)EnsemblGRCm39 Ensembl
GRCm38744,382,773 - 44,400,030 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl744,384,102 - 44,400,187 (+)EnsemblGRCm38mm10GRCm38
MGSCv37751,639,496 - 51,655,400 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,252,863 - 44,268,071 (+)NCBIMGSCv36mm8
Celera739,842,838 - 39,858,700 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.83NCBI
Syt3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,017,341 - 104,032,046 (+)NCBIGRCr8
mRatBN7.2194,880,835 - 94,895,518 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl194,881,247 - 94,895,246 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,266,994 - 100,280,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01108,739,638 - 108,753,304 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,030,066 - 102,043,728 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01100,379,236 - 100,407,862 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1100,379,186 - 100,408,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01101,459,003 - 101,473,576 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4194,866,807 - 94,880,457 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1194,944,917 - 94,958,568 (+)NCBI
Celera189,144,345 - 89,157,982 (+)NCBICelera
RH 3.4 Map1904.6RGD
Cytogenetic Map1q22NCBI
Syt3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955559580,453 - 593,109 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955559580,453 - 591,938 (+)NCBIChiLan1.0ChiLan1.0
SYT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22056,688,417 - 56,706,568 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11958,601,704 - 58,627,689 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01947,585,801 - 47,604,094 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11956,486,894 - 56,522,803 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1956,486,894 - 56,503,574 (-)Ensemblpanpan1.1panPan2
SYT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,145,524 - 106,160,942 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,145,356 - 106,160,942 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,719,785 - 105,735,219 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,657,430 - 106,672,865 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,657,419 - 106,672,863 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11106,329,543 - 106,344,979 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,971,127 - 105,986,557 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,811,745 - 106,827,186 (+)NCBIUU_Cfam_GSD_1.0
Syt3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934922,528,529 - 22,535,901 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936889404,534 - 411,885 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1643,678,535 - 43,698,347 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl643,677,790 - 43,697,766 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607323,694,790 - 23,713,460 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syt3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,991,491 - 4,003,608 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248323,991,289 - 4,003,608 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SYT3
299 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium
Low 4 2 1 4 21 1 1 2
Below cutoff 6 2 1 2 1 2

Sequence


RefSeq Acc Id: ENSSSCT00000003581   ⟹   ENSSSCP00000003498
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl655,417,951 - 55,434,175 (-)Ensembl
RefSeq Acc Id: XM_003127368   ⟹   XP_003127416
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,437,105 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013998700   ⟹   XP_013854154
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,434,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013998701   ⟹   XP_013854155
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,434,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013998702   ⟹   XP_013854156
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,434,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013998704   ⟹   XP_013854158
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,434,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094803   ⟹   XP_020950462
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,437,127 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094804   ⟹   XP_020950463
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,448,408 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094805   ⟹   XP_020950464
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,449,322 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021094807   ⟹   XP_020950466
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1655,417,949 - 55,433,919 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020950464   ⟸   XM_021094805
- Peptide Label: isoform X3
- UniProtKB: A0A8D0T193 (UniProtKB/TrEMBL),   F1RH13 (UniProtKB/TrEMBL),   A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950463   ⟸   XM_021094804
- Peptide Label: isoform X2
- UniProtKB: A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950462   ⟸   XM_021094803
- Peptide Label: isoform X1
- UniProtKB: A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003127416   ⟸   XM_003127368
- Peptide Label: isoform X3
- UniProtKB: A0A8D0T193 (UniProtKB/TrEMBL),   F1RH13 (UniProtKB/TrEMBL),   A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013854158   ⟸   XM_013998704
- Peptide Label: isoform X3
- UniProtKB: F1RH13 (UniProtKB/TrEMBL),   A0A8D0T193 (UniProtKB/TrEMBL),   A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013854156   ⟸   XM_013998702
- Peptide Label: isoform X3
- UniProtKB: F1RH13 (UniProtKB/TrEMBL),   A0A8D0T193 (UniProtKB/TrEMBL),   A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013854155   ⟸   XM_013998701
- Peptide Label: isoform X3
- UniProtKB: F1RH13 (UniProtKB/TrEMBL),   A0A8D0T193 (UniProtKB/TrEMBL),   A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013854154   ⟸   XM_013998700
- Peptide Label: isoform X3
- UniProtKB: F1RH13 (UniProtKB/TrEMBL),   A0A8D0T193 (UniProtKB/TrEMBL),   A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020950466   ⟸   XM_021094807
- Peptide Label: isoform X3
- UniProtKB: A0A8D0T193 (UniProtKB/TrEMBL),   F1RH13 (UniProtKB/TrEMBL),   A0A8D0MZ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000003498   ⟸   ENSSSCT00000003581
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003222 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015018833 UniProtKB/TrEMBL
  ENSSSCG00025066093 UniProtKB/TrEMBL
  ENSSSCG00030000050 UniProtKB/TrEMBL
  ENSSSCG00035043400 UniProtKB/TrEMBL
  ENSSSCG00040007451 UniProtKB/TrEMBL
  ENSSSCG00045024098 UniProtKB/TrEMBL
  ENSSSCG00050075548 UniProtKB/TrEMBL
  ENSSSCG00055016461 UniProtKB/TrEMBL
  ENSSSCG00060010908 UniProtKB/TrEMBL
  ENSSSCG00065076875 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000003581 ENTREZGENE
  ENSSSCT00000003581.5 UniProtKB/TrEMBL
  ENSSSCT00015024887.1 UniProtKB/TrEMBL
  ENSSSCT00025090795.1 UniProtKB/TrEMBL
  ENSSSCT00030000113.1 UniProtKB/TrEMBL
  ENSSSCT00035057656.1 UniProtKB/TrEMBL
  ENSSSCT00040009807.1 UniProtKB/TrEMBL
  ENSSSCT00045041119.1 UniProtKB/TrEMBL
  ENSSSCT00050103627.1 UniProtKB/TrEMBL
  ENSSSCT00055032527.1 UniProtKB/TrEMBL
  ENSSSCT00060014210.1 UniProtKB/TrEMBL
  ENSSSCT00065106267.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Synaptotagmin UniProtKB/TrEMBL
NCBI Gene SYT3 ENTREZGENE
PANTHER PTHR10024:SF176 UniProtKB/TrEMBL
  SYNAPTOTAGMIN UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
  SYNAPTOTAGMN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8D0MZ56 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0T193 ENTREZGENE, UniProtKB/TrEMBL
  F1RH13 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:93684 ENTREZGENE