IFITM3 (interferon induced transmembrane protein 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: IFITM3 (interferon induced transmembrane protein 3) Sus scrofa
Analyze
Symbol: IFITM3
Name: interferon induced transmembrane protein 3
RGD ID: 14125691
Description: INVOLVED IN negative regulation of viral transcription (ortholog); response to virus (ortholog); ASSOCIATED WITH Beckwith-Wiedemann syndrome (ortholog); COVID-19 (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN early endosome membrane (ortholog); lysosomal membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IFITM2; interferon induced transmembrane protein 2; interferon induced transmembrane protein 2 (1-8D); interferon-induced transmembrane protein 2; interferon-induced transmembrane protein 3
RGD Orthologs
Human
Mouse
Rat
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2127,152 - 129,835 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12128,658 - 129,736 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22162,072,261 - 162,072,507 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:24656980   PMID:24973762   PMID:27374903   PMID:30032202   PMID:32745511   PMID:32838949   PMID:32999030   PMID:38484578  


Genomics

Comparative Map Data
IFITM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2127,152 - 129,835 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12128,658 - 129,736 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22162,072,261 - 162,072,507 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IFITM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811319,676 - 320,860 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11319,676 - 329,475 (-)EnsemblGRCh38hg38GRCh38
GRCh3711319,676 - 320,860 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611309,673 - 310,914 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411309,668 - 311,050NCBI
Cytogenetic Map11p15.5NCBI
HuRef11137,979 - 139,220 (-)NCBIHuRef
CHM1_111318,636 - 319,877 (-)NCBICHM1_1
T2T-CHM13v2.011360,910 - 362,094 (-)NCBIT2T-CHM13v2.0
Ifitm3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,589,503 - 140,590,657 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7140,589,499 - 140,590,683 (-)EnsemblGRCm39 Ensembl
GRCm387141,009,590 - 141,010,744 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,009,586 - 141,010,770 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,195,489 - 148,196,643 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367140,860,910 - 140,862,064 (-)NCBIMGSCv36mm8
Celera7140,802,289 - 140,803,443 (-)NCBICelera
Cytogenetic Map7F5NCBI
cM Map786.25NCBI
Ifitm3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81205,540,649 - 205,541,758 (-)NCBIGRCr8
mRatBN7.21196,111,026 - 196,112,135 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1196,111,043 - 196,112,203 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1204,456,782 - 204,457,903 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01211,583,367 - 211,584,488 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01204,257,495 - 204,258,616 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01213,810,712 - 213,811,821 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,810,696 - 213,811,901 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,730,715 - 220,731,824 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,198,659 - 201,199,768 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1193,745,524 - 193,746,633 (-)NCBICelera
Cytogenetic Map1q41NCBI
LOC475935
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,484,731 - 25,485,927 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,134,337 - 25,135,526 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01826,068,903 - 26,070,152 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11825,579,473 - 25,580,663 (+)NCBIUMICH_Zoey_3.1
UU_Cfam_GSD_1.01825,836,658 - 25,837,846 (+)NCBIUU_Cfam_GSD_1.0
LOC103238550
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11147,228 - 148,078 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603897,176,566 - 97,188,322 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in IFITM3
35 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000058772   ⟹   ENSSSCP00000052363
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2128,273 - 129,835 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000080728   ⟹   ENSSSCP00000060193
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl2127,152 - 129,801 (-)Ensembl
RefSeq Acc Id: NM_001201382   ⟹   NP_001188311
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.12128,658 - 129,736 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001188311   ⟸   NM_001201382
- UniProtKB: E7EAX3 (UniProtKB/TrEMBL),   A0A0B8RSR9 (UniProtKB/TrEMBL),   A0A142EGG6 (UniProtKB/TrEMBL),   A0A8D0UH87 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000052363   ⟸   ENSSSCT00000058772
Ensembl Acc Id: ENSSSCP00000060193   ⟸   ENSSSCT00000080728


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038912 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00025009040 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000080728.1 UniProtKB/TrEMBL
  ENSSSCT00025011987.1 UniProtKB/TrEMBL
InterPro CD225/Dispanin_fam UniProtKB/TrEMBL
  IFITM_antiviral_protein UniProtKB/TrEMBL
KEGG Report ssc:100518544 UniProtKB/TrEMBL
NCBI Gene IFITM3 ENTREZGENE
PANTHER INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN UniProtKB/TrEMBL
  INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 UniProtKB/TrEMBL
Pfam CD225 UniProtKB/TrEMBL
UniProt A0A0B8RSR9 ENTREZGENE
  A0A142EGG5_PIG UniProtKB/TrEMBL
  A0A142EGG6 ENTREZGENE, UniProtKB/TrEMBL
  A0A480MY90_PIG UniProtKB/TrEMBL
  A0A5G2QA15_PIG UniProtKB/TrEMBL
  A0A8D0UH87 ENTREZGENE, UniProtKB/TrEMBL
  E7EAX3 ENTREZGENE, UniProtKB/TrEMBL
  F4ZS15_PIG UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-11-09 IFITM3  interferon induced transmembrane protein 3  IFITM2  interferon induced transmembrane protein 2  Data merged from RGD:13903098 737654 PROVISIONAL