RORA (RAR related orphan receptor A) - Rat Genome Database

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Gene: RORA (RAR related orphan receptor A) Sus scrofa
Analyze
Symbol: RORA
Name: RAR related orphan receptor A
RGD ID: 14121219
Description: ENCODES a protein that exhibits beta-catenin binding (inferred); DNA binding (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cellular response to interleukin-1 (ortholog); cellular response to tumor necrosis factor (ortholog); cerebellar Purkinje cell differentiation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN nucleolus (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nuclear receptor ROR-alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1111,375,457 - 111,477,703 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11110,719,004 - 111,482,807 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21123,140,609 - 123,247,974 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IEA)
nucleus  (IBA,IEA)

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RORA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1111,375,457 - 111,477,703 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11110,719,004 - 111,482,807 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21123,140,609 - 123,247,974 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RORA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381560,488,284 - 61,229,302 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1560,488,284 - 61,229,302 (-)EnsemblGRCh38hg38GRCh38
GRCh371560,780,483 - 61,521,501 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361558,576,755 - 59,308,794 (-)NCBINCBI36Build 36hg18NCBI36
Build 341558,576,754 - 58,671,999NCBI
Celera1537,669,158 - 37,859,340 (-)NCBICelera
Cytogenetic Map15q22.2NCBI
HuRef1537,602,935 - 37,793,081 (-)NCBIHuRef
CHM1_11560,900,085 - 61,640,967 (-)NCBICHM1_1
T2T-CHM13v2.01558,291,519 - 59,032,551 (-)NCBIT2T-CHM13v2.0
Rora
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39968,560,627 - 69,295,528 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl968,561,068 - 69,295,528 (+)EnsemblGRCm39 Ensembl
GRCm38968,653,404 - 69,388,246 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl968,653,786 - 69,388,246 (+)EnsemblGRCm38mm10GRCm38
MGSCv37968,501,609 - 69,226,838 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36968,452,966 - 69,178,195 (+)NCBIMGSCv36mm8
Celera965,876,634 - 66,600,643 (+)NCBICelera
Cytogenetic Map9CNCBI
cM Map937.45NCBI
Rora
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8878,182,710 - 78,915,730 (+)NCBIGRCr8
mRatBN7.2869,301,635 - 70,034,741 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl869,301,733 - 70,025,931 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0875,515,886 - 75,616,477 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl875,516,904 - 75,607,212 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0879,195,918 - 79,934,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4873,052,282 - 73,817,764 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1873,744,425 - 73,837,420 (+)NCBI
Celera871,690,522 - 71,789,466 (-)NCBICelera
Cytogenetic Map8q24NCBI
Rora
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545014,262,190 - 14,425,233 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545014,262,199 - 14,434,611 (+)NCBIChiLan1.0ChiLan1.0
RORA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21649,756,431 - 50,500,133 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11553,939,419 - 54,677,888 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01539,461,553 - 40,200,118 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11557,763,345 - 57,901,854 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1557,771,735 - 57,980,460 (-)Ensemblpanpan1.1panPan2
RORA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13025,315,974 - 26,026,708 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3025,325,275 - 26,026,623 (-)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3025,391,427 - 25,943,891 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03025,492,382 - 26,204,624 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3025,499,048 - 26,204,099 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13025,420,874 - 26,136,597 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03025,497,210 - 26,208,111 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03025,727,551 - 26,439,038 (-)NCBIUU_Cfam_GSD_1.0
Rora
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640103,544,814 - 104,221,651 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647121,400,589 - 22,069,643 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647121,402,056 - 21,567,908 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RORA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12622,263,889 - 23,002,224 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2622,812,445 - 22,993,021 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048118,365,025 - 119,123,454 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rora
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478111,014,286 - 11,679,678 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478111,014,185 - 11,688,558 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RORA
15224 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000005055   ⟹   ENSSSCP00000004933
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1111,436,830 - 111,477,106 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000057944   ⟹   ENSSSCP00000031686
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1111,375,457 - 111,477,703 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000080573   ⟹   ENSSSCP00000069819
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1111,436,702 - 111,477,703 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000083166   ⟹   ENSSSCP00000063180
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1111,435,985 - 111,477,703 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000092451   ⟹   ENSSSCP00000074790
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1111,427,235 - 111,475,976 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000104420   ⟹   ENSSSCP00000080783
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1111,436,412 - 111,475,976 (+)Ensembl
RefSeq Acc Id: XM_001928154   ⟹   XP_001928189
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11111,375,380 - 111,482,807 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005659540   ⟹   XP_005659597
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11111,426,458 - 111,482,807 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073474   ⟹   XP_020929133
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11110,719,004 - 111,482,807 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021073481   ⟹   XP_020929140
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11111,107,413 - 111,482,807 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020929133   ⟸   XM_021073474
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TT76 (UniProtKB/TrEMBL),   F1S075 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020929140   ⟸   XM_021073481
- Peptide Label: isoform X2
- UniProtKB: F1S075 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_001928189   ⟸   XM_001928154
- Peptide Label: isoform X4
- UniProtKB: A0A286ZJH8 (UniProtKB/TrEMBL),   A0A4X1TNF7 (UniProtKB/TrEMBL),   F1S075 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005659597   ⟸   XM_005659540
- Peptide Label: isoform X3
- UniProtKB: A0A8D1QKE4 (UniProtKB/TrEMBL),   F1S075 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000063180   ⟸   ENSSSCT00000083166
Ensembl Acc Id: ENSSSCP00000004933   ⟸   ENSSSCT00000005055
Ensembl Acc Id: ENSSSCP00000069819   ⟸   ENSSSCT00000080573
Ensembl Acc Id: ENSSSCP00000031686   ⟸   ENSSSCT00000057944
Ensembl Acc Id: ENSSSCP00000074790   ⟸   ENSSSCT00000092451
Ensembl Acc Id: ENSSSCP00000080783   ⟸   ENSSSCT00000104420
Protein Domains
NR LBD   Nuclear receptor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004576 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015058554 UniProtKB/TrEMBL
  ENSSSCG00025012503 UniProtKB/TrEMBL
  ENSSSCG00030021094 UniProtKB/TrEMBL
  ENSSSCG00035063778 UniProtKB/TrEMBL
  ENSSSCG00040039343 UniProtKB/TrEMBL
  ENSSSCG00045026615 UniProtKB/TrEMBL
  ENSSSCG00050064554 UniProtKB/TrEMBL
  ENSSSCG00055014079 UniProtKB/TrEMBL
  ENSSSCG00060068552 UniProtKB/TrEMBL
  ENSSSCG00065001665 UniProtKB/TrEMBL
  ENSSSCG00070011469 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000005055.5 UniProtKB/TrEMBL
  ENSSSCT00000057944 ENTREZGENE
  ENSSSCT00000057944.2 UniProtKB/TrEMBL
  ENSSSCT00000080573.2 UniProtKB/TrEMBL
  ENSSSCT00000083166.1 UniProtKB/TrEMBL
  ENSSSCT00000092451 ENTREZGENE
  ENSSSCT00000092451.1 UniProtKB/TrEMBL
  ENSSSCT00000104420.1 UniProtKB/TrEMBL
  ENSSSCT00015078301.1 UniProtKB/TrEMBL
  ENSSSCT00015078673.1 UniProtKB/TrEMBL
  ENSSSCT00025016910.1 UniProtKB/TrEMBL
  ENSSSCT00030029363.1 UniProtKB/TrEMBL
  ENSSSCT00035085854.1 UniProtKB/TrEMBL
  ENSSSCT00040052678.1 UniProtKB/TrEMBL
  ENSSSCT00045045942.1 UniProtKB/TrEMBL
  ENSSSCT00050087942.1 UniProtKB/TrEMBL
  ENSSSCT00055027824.1 UniProtKB/TrEMBL
  ENSSSCT00055027962.1 UniProtKB/TrEMBL
  ENSSSCT00060093704.1 UniProtKB/TrEMBL
  ENSSSCT00065002082.1 UniProtKB/TrEMBL
  ENSSSCT00065002098.1 UniProtKB/TrEMBL
  ENSSSCT00070022366.1 UniProtKB/TrEMBL
  ENSSSCT00070022387.1 UniProtKB/TrEMBL
  ENSSSCT00070022405.1 UniProtKB/TrEMBL
  ENSSSCT00070022415.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.565.10 UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/TrEMBL
InterPro NHR_like_dom_sf UniProtKB/TrEMBL
  NR_DBD_ROR UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/TrEMBL
  ROR_rcpt UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/TrEMBL
KEGG Report ssc:100156637 UniProtKB/TrEMBL
NCBI Gene RORA ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR HR3-RELATED UniProtKB/TrEMBL
  NUCLEAR RECEPTOR ROR-ALPHA UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/TrEMBL
  zf-C4 UniProtKB/TrEMBL
PRINTS RORNUCRECPTR UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/TrEMBL
SMART HOLI UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  SSF48508 UniProtKB/TrEMBL
UniProt A0A286ZJH8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TNF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TQM1_PIG UniProtKB/TrEMBL
  A0A4X1TT76 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1TTD4_PIG UniProtKB/TrEMBL
  A0A5G2QH74_PIG UniProtKB/TrEMBL
  A0A5G2RFK4_PIG UniProtKB/TrEMBL
  A0A8D1QKE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4F919_PIG UniProtKB/TrEMBL
  A0A8W4FPD8_PIG UniProtKB/TrEMBL
  F1S075 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92408 ENTREZGENE