SERPIND1 (serpin family D member 1) - Rat Genome Database

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Gene: SERPIND1 (serpin family D member 1) Sus scrofa
Analyze
Symbol: SERPIND1
Name: serpin family D member 1
RGD ID: 14091960
Description: ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (inferred); INVOLVED IN blood coagulation (inferred); negative regulation of endopeptidase activity (inferred); ASSOCIATED WITH autistic disorder (ortholog); carotid artery thrombosis (ortholog); DiGeorge syndrome (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heparin cofactor 2; heparin cofactor II; serpin peptidase inhibitor clade D member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,427,115 - 50,436,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,427,121 - 50,436,470 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,875,835 - 53,885,198 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
SERPIND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1450,427,115 - 50,436,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11450,427,121 - 50,436,470 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,875,835 - 53,885,198 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SERPIND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382220,774,113 - 20,787,720 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2220,774,113 - 20,787,720 (+)EnsemblGRCh38hg38GRCh38
GRCh372221,128,401 - 21,142,008 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362219,458,383 - 19,472,008 (+)NCBINCBI36hg18NCBI36
Build 342219,452,940 - 19,466,562NCBI
Celera224,619,743 - 4,633,367 (+)NCBI
Cytogenetic Map22q11.21ENTREZGENE
HuRef224,396,258 - 4,409,872 (+)NCBIHuRef
CHM1_12221,128,573 - 21,142,203 (+)NCBICHM1_1
T2T-CHM13v2.02221,182,821 - 21,196,428 (+)NCBI
Serpind1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,149,235 - 17,161,438 (+)NCBIGRCm39mm39
GRCm39 Ensembl1617,149,235 - 17,161,439 (+)Ensembl
GRCm381617,331,371 - 17,343,574 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,331,371 - 17,343,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv371617,331,464 - 17,343,665 (+)NCBIGRCm37mm9NCBIm37
MGSCv361617,244,978 - 17,257,135 (+)NCBImm8
Celera1617,904,289 - 17,916,527 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.74NCBI
Serpind1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21183,664,517 - 83,675,593 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1183,664,518 - 83,675,519 (-)Ensembl
Rnor_6.01187,913,814 - 87,924,880 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,913,806 - 87,924,816 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01190,969,513 - 90,980,577 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,666,714 - 85,677,716 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11185,707,310 - 85,718,313 (-)NCBI
Celera1182,428,108 - 82,439,110 (-)NCBICelera
Cytogenetic Map11q23NCBI
Serpind1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544219,525,411 - 19,538,384 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544219,525,411 - 19,537,986 (-)NCBIChiLan1.0ChiLan1.0
SERPIND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12219,488,733 - 19,502,380 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2219,488,733 - 19,502,380 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0222,997,480 - 3,011,469 (+)NCBIMhudiblu_PPA_v0panPan3
SERPIND1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12630,686,074 - 30,697,437 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2630,686,663 - 30,693,848 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2630,644,440 - 30,655,802 (-)NCBI
ROS_Cfam_1.02632,092,332 - 32,104,026 (-)NCBI
ROS_Cfam_1.0 Ensembl2632,092,321 - 32,100,437 (-)Ensembl
UMICH_Zoey_3.12630,140,268 - 30,151,742 (-)NCBI
UNSW_CanFamBas_1.02629,765,126 - 29,776,487 (-)NCBI
UU_Cfam_GSD_1.02630,854,649 - 30,866,010 (-)NCBI
Serpind1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118140,443,481 - 140,455,345 (-)NCBI
SpeTri2.0NW_0049366192,298,745 - 2,310,740 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPIND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,709,896 - 4,724,620 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl194,715,806 - 4,726,111 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660852,274,595 - 2,288,806 (-)NCBIVero_WHO_p1.0
Serpind1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624945915,789 - 932,515 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_004624945919,639 - 932,515 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000011054   ⟹   ENSSSCP00000010766
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1450,427,115 - 50,436,468 (+)Ensembl
RefSeq Acc Id: XM_001929566   ⟹   XP_001929601
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11450,427,121 - 50,436,470 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_001929601 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AEA40674 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_001929601   ⟸   XM_001929566
- UniProtKB: F1RKY2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010766   ⟸   ENSSSCT00000011054
Protein Domains
SERPIN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010093 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005027196 UniProtKB/TrEMBL
  ENSSSCG00015037172 UniProtKB/TrEMBL
  ENSSSCG00025042472 UniProtKB/TrEMBL
  ENSSSCG00030074140 UniProtKB/TrEMBL
  ENSSSCG00035065343 UniProtKB/TrEMBL
  ENSSSCG00040073155 UniProtKB/TrEMBL
  ENSSSCG00045012058 UniProtKB/TrEMBL
  ENSSSCG00050058276 UniProtKB/TrEMBL
  ENSSSCG00055028806 UniProtKB/TrEMBL
  ENSSSCG00060037508 UniProtKB/TrEMBL
  ENSSSCG00065054225 UniProtKB/TrEMBL
  ENSSSCG00070020415 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000010766 ENTREZGENE
  ENSSSCP00000010766.3 UniProtKB/TrEMBL
  ENSSSCP00005026408.1 UniProtKB/TrEMBL
  ENSSSCP00015019767.1 UniProtKB/TrEMBL
  ENSSSCP00025024350.1 UniProtKB/TrEMBL
  ENSSSCP00030048101.1 UniProtKB/TrEMBL
  ENSSSCP00035036767.1 UniProtKB/TrEMBL
  ENSSSCP00040045370.1 UniProtKB/TrEMBL
  ENSSSCP00045014059.1 UniProtKB/TrEMBL
  ENSSSCP00045014075.1 UniProtKB/TrEMBL
  ENSSSCP00050034157.1 UniProtKB/TrEMBL
  ENSSSCP00055045714.1 UniProtKB/TrEMBL
  ENSSSCP00055045734.1 UniProtKB/TrEMBL
  ENSSSCP00060021671.1 UniProtKB/TrEMBL
  ENSSSCP00065032361.1 UniProtKB/TrEMBL
  ENSSSCP00070034028.1 UniProtKB/TrEMBL
  ENSSSCP00070034031.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000011054 ENTREZGENE
  ENSSSCT00000011054.4 UniProtKB/TrEMBL
  ENSSSCT00005043095.1 UniProtKB/TrEMBL
  ENSSSCT00015049607.1 UniProtKB/TrEMBL
  ENSSSCT00025057539.1 UniProtKB/TrEMBL
  ENSSSCT00030103946.1 UniProtKB/TrEMBL
  ENSSSCT00035088028.1 UniProtKB/TrEMBL
  ENSSSCT00040100872.1 UniProtKB/TrEMBL
  ENSSSCT00045020460.1 UniProtKB/TrEMBL
  ENSSSCT00045020483.1 UniProtKB/TrEMBL
  ENSSSCT00050079445.1 UniProtKB/TrEMBL
  ENSSSCT00055057146.1 UniProtKB/TrEMBL
  ENSSSCT00055057172.1 UniProtKB/TrEMBL
  ENSSSCT00060050762.1 UniProtKB/TrEMBL
  ENSSSCT00065074284.1 UniProtKB/TrEMBL
  ENSSSCT00070040559.1 UniProtKB/TrEMBL
  ENSSSCT00070040562.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
InterPro HCII_serpin_dom UniProtKB/TrEMBL
  Serpin_CS UniProtKB/TrEMBL
  Serpin_dom UniProtKB/TrEMBL
  Serpin_fam UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
KEGG Report ssc:100155945 UniProtKB/TrEMBL
NCBI Gene SERPIND1 ENTREZGENE
PANTHER PTHR11461 UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PROSITE SERPIN UniProtKB/TrEMBL
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP SSF56574 UniProtKB/TrEMBL
UniProt A0A481BLI9_PIG UniProtKB/TrEMBL
  A0A4X1UYS0_PIG UniProtKB/TrEMBL
  A0A8D0JJ69_PIG UniProtKB/TrEMBL
  F1RKY2 ENTREZGENE, UniProtKB/TrEMBL
  H9LBP0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:92741 ENTREZGENE