CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit) Sus scrofa
Analyze
Symbol: CHRNA9
Name: cholinergic receptor nicotinic alpha 9 subunit
RGD ID: 14088398
Description: ENCODES a protein that exhibits acetylcholine-gated monoatomic cation-selective channel activity (ortholog); transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN detection of mechanical stimulus involved in sensory perception of sound (ortholog); inner ear morphogenesis (ortholog); monoatomic cation transport (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH Hyperglycinemia, Lactic Acidosis, and Seizures (ortholog); lung small cell carcinoma (ortholog); Neoplastic Cell Transformation (ortholog); FOUND IN acetylcholine-gated channel complex (ortholog); cholinergic synapse (ortholog); postsynaptic specialization membrane (ortholog); INTERACTS WITH (S)-nicotine; carbon dioxide; dioxygen
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: neuronal acetylcholine receptor subunit alpha-9
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl831,443,043 - 31,456,384 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1831,430,933 - 31,456,385 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2833,099,230 - 33,123,294 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CHRNA9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl831,443,043 - 31,456,384 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1831,430,933 - 31,456,385 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2833,099,230 - 33,123,294 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHRNA9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38440,335,333 - 40,355,217 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl440,335,333 - 40,355,217 (+)EnsemblGRCh38hg38GRCh38
GRCh37440,337,350 - 40,357,234 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36440,032,226 - 40,051,730 (+)NCBINCBI36Build 36hg18NCBI36
Build 34440,178,396 - 40,197,901NCBI
Celera440,778,936 - 40,798,410 (+)NCBICelera
Cytogenetic Map4p14NCBI
HuRef439,659,308 - 39,679,373 (+)NCBIHuRef
CHM1_1440,336,462 - 40,356,347 (+)NCBICHM1_1
T2T-CHM13v2.0440,309,008 - 40,328,903 (+)NCBIT2T-CHM13v2.0
Chrna9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39566,092,317 - 66,134,823 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl566,092,264 - 66,134,669 (+)EnsemblGRCm39 Ensembl
GRCm38565,934,854 - 65,977,486 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl565,934,921 - 65,977,326 (+)EnsemblGRCm38mm10GRCm38
MGSCv37566,358,363 - 66,368,725 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36566,246,259 - 66,256,621 (+)NCBIMGSCv36mm8
Celera563,263,725 - 63,274,240 (+)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map533.84NCBI
Chrna9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81442,588,948 - 42,595,669 (-)NCBIGRCr8
mRatBN7.21442,235,218 - 42,241,939 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,235,226 - 42,242,192 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1442,589,138 - 42,595,865 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01443,889,187 - 43,895,914 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01442,369,041 - 42,375,781 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01443,883,450 - 43,890,171 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1443,883,458 - 43,890,171 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01443,670,525 - 43,677,246 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41444,906,566 - 44,913,821 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11444,908,960 - 44,916,212 (-)NCBI
Celera1441,388,099 - 41,394,795 (-)NCBICelera
Cytogenetic Map14p11NCBI
Chrna9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554437,148,604 - 7,157,824 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554437,148,604 - 7,157,824 (-)NCBIChiLan1.0ChiLan1.0
CHRNA9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2340,513,841 - 40,536,734 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1440,705,676 - 40,728,580 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0434,654,043 - 34,675,984 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1440,509,475 - 40,528,869 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl440,509,475 - 40,528,869 (+)Ensemblpanpan1.1panPan2
CHRNA9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1372,190,431 - 72,204,092 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl372,190,555 - 72,203,404 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha374,738,924 - 74,752,324 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0372,956,919 - 72,970,323 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl372,956,998 - 72,985,424 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1372,219,775 - 72,233,167 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0372,376,073 - 72,389,479 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0372,760,280 - 72,773,685 (-)NCBIUU_Cfam_GSD_1.0
Chrna9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528538,495,169 - 38,506,158 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364827,792,292 - 7,801,152 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364827,792,292 - 7,801,152 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRNA9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1279,952,344 - 9,979,638 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl279,953,115 - 9,971,811 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604756,318,015 - 56,338,505 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chrna9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476126,636,506 - 26,645,471 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476126,636,242 - 26,646,072 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CHRNA9
1138 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
8 2 20 1 2 5 7 7 20 1 3

Sequence


Ensembl Acc Id: ENSSSCT00000032423   ⟹   ENSSSCP00000026083
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl831,443,043 - 31,456,384 (+)Ensembl
RefSeq Acc Id: NM_001244806   ⟹   NP_001231735
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1831,443,043 - 31,456,384 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013978601   ⟹   XP_013834055
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1831,441,913 - 31,456,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013978602   ⟹   XP_013834056
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1831,430,933 - 31,456,385 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013978603   ⟹   XP_013834057
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1831,440,804 - 31,456,385 (+)NCBI
Sequence:
RefSeq Acc Id: XP_013834056   ⟸   XM_013978602
- Peptide Label: isoform X2
- UniProtKB: I3LPQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834057   ⟸   XM_013978603
- Peptide Label: isoform X2
- UniProtKB: I3LPQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013834055   ⟸   XM_013978601
- Peptide Label: isoform X1
- UniProtKB: I3LPQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231735   ⟸   NM_001244806
- Peptide Label: precursor
- UniProtKB: A0A4X1UYD6 (UniProtKB/TrEMBL),   A0A8D1Z414 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000026083   ⟸   ENSSSCT00000032423

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000024428 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005004388 UniProtKB/TrEMBL
  ENSSSCG00015032832 UniProtKB/TrEMBL
  ENSSSCG00025065456 UniProtKB/TrEMBL
  ENSSSCG00030022864 UniProtKB/TrEMBL
  ENSSSCG00035043934 UniProtKB/TrEMBL
  ENSSSCG00040027672 UniProtKB/TrEMBL
  ENSSSCG00045027467 UniProtKB/TrEMBL
  ENSSSCG00050024073 UniProtKB/TrEMBL
  ENSSSCG00055020678 UniProtKB/TrEMBL
  ENSSSCG00060022840 UniProtKB/TrEMBL
  ENSSSCG00065048417 UniProtKB/TrEMBL
  ENSSSCG00070020580 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000032423 ENTREZGENE
  ENSSSCT00000032423.2 UniProtKB/TrEMBL
  ENSSSCT00005006549.1 UniProtKB/TrEMBL
  ENSSSCT00015043472.1 UniProtKB/TrEMBL
  ENSSSCT00025089827.1 UniProtKB/TrEMBL
  ENSSSCT00030031734.1 UniProtKB/TrEMBL
  ENSSSCT00035058374.1 UniProtKB/TrEMBL
  ENSSSCT00040037052.1 UniProtKB/TrEMBL
  ENSSSCT00045046767.1 UniProtKB/TrEMBL
  ENSSSCT00050032439.1 UniProtKB/TrEMBL
  ENSSSCT00055040554.1 UniProtKB/TrEMBL
  ENSSSCT00060031001.1 UniProtKB/TrEMBL
  ENSSSCT00065066226.1 UniProtKB/TrEMBL
  ENSSSCT00070040913.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/TrEMBL
InterPro Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/TrEMBL
  Nicotinic_acetylcholine_rcpt UniProtKB/TrEMBL
NCBI Gene CHRNA9 ENTREZGENE
PANTHER NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 UniProtKB/TrEMBL
  PTHR18945 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS NICOTINICR UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
UniProt A0A4X1UYD6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0NHA3_PIG UniProtKB/TrEMBL
  A0A8D1LTR7_PIG UniProtKB/TrEMBL
  A0A8D1Z414 ENTREZGENE, UniProtKB/TrEMBL
  I3LPQ6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:86671 ENTREZGENE