ABCB7 (ATP binding cassette subfamily B member 7) - Rat Genome Database

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Gene: ABCB7 (ATP binding cassette subfamily B member 7) Sus scrofa
Analyze
Symbol: ABCB7
Name: ATP binding cassette subfamily B member 7
RGD ID: 14067376
Description: ENCODES a protein that exhibits ABC-type iron-sulfur cluster transporter activity (inferred); ABC-type transporter activity (inferred); ATP binding (inferred); INVOLVED IN intracellular iron ion homeostasis (ortholog); negative regulation of reactive oxygen species biosynthetic process (ortholog); PARTICIPATES IN mitochondrial iron-sulfur cluster export pathway; ASSOCIATED WITH Ataxia (ortholog); autistic disorder (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette sub-family B member 7, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX60,186,814 - 60,313,064 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X60,186,559 - 60,313,098 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X68,395,504 - 68,522,015 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ABCB7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX60,186,814 - 60,313,064 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X60,186,559 - 60,313,098 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X68,395,504 - 68,522,015 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABCB7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X75,051,048 - 75,156,283 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX75,051,048 - 75,156,732 (-)EnsemblGRCh38hg38GRCh38
GRCh37X74,270,883 - 74,376,118 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X74,189,830 - 74,292,857 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X74,056,127 - 74,159,153NCBI
CeleraX74,556,536 - 74,659,552 (-)NCBICelera
Cytogenetic MapXq13.3NCBI
HuRefX67,906,559 - 68,010,008 (-)NCBIHuRef
CHM1_1X74,165,916 - 74,269,046 (-)NCBICHM1_1
T2T-CHM13v2.0X73,484,682 - 73,589,943 (-)NCBIT2T-CHM13v2.0
Abcb7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X103,324,171 - 103,457,452 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX103,324,263 - 103,457,462 (-)EnsemblGRCm39 Ensembl
GRCm38X104,280,565 - 104,413,846 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX104,280,657 - 104,413,856 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X101,475,904 - 101,609,185 (-)NCBIGRCm37MGSCv37mm9NCBIm37
CeleraX91,172,735 - 91,305,783 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX46.58NCBI
Abcb7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X73,361,296 - 73,502,464 (-)NCBIGRCr8
mRatBN7.2X69,295,598 - 69,436,775 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX69,295,552 - 69,436,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX70,804,692 - 70,945,868 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X74,304,987 - 74,446,162 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X71,866,179 - 72,007,358 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X75,150,511 - 75,291,950 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX75,150,608 - 75,291,938 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X75,954,591 - 76,094,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X92,280,115 - 92,430,426 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X92,353,547 - 92,503,859 (-)NCBI
CeleraX70,651,391 - 70,791,324 (-)NCBICelera
Cytogenetic MapXq22NCBI
Abcb7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555621,077,198 - 1,221,061 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555621,079,884 - 1,220,806 (-)NCBIChiLan1.0ChiLan1.0
ABCB7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X74,734,492 - 74,838,145 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X74,738,102 - 74,841,298 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X64,304,101 - 64,407,310 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X74,418,754 - 74,521,726 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX74,418,754 - 74,521,726 (-)Ensemblpanpan1.1panPan2
ABCB7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X58,305,804 - 58,470,827 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX58,306,776 - 58,471,417 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX49,482,770 - 49,647,336 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X59,542,308 - 59,707,158 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX59,540,916 - 59,707,267 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X57,230,770 - 57,395,118 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X58,850,296 - 59,014,604 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X58,448,856 - 58,613,397 (-)NCBIUU_Cfam_GSD_1.0
Abcb7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X43,621,036 - 43,722,688 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366831,222,450 - 1,326,765 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366831,224,703 - 1,326,761 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCB7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X64,633,989 - 64,748,638 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX64,634,079 - 64,701,938 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606716,958,476 - 17,074,666 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcb7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248365,605,831 - 5,766,275 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248365,605,901 - 5,769,488 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ABCB7
2229 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 2 4 3 1
Low 8 2 3 1 2 20 1 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000013585   ⟹   ENSSSCP00000013220
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX60,121,584 - 60,313,049 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000033898   ⟹   ENSSSCP00000029568
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX60,187,397 - 60,313,049 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000036440   ⟹   ENSSSCP00000028898
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX60,187,397 - 60,313,049 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000038920   ⟹   ENSSSCP00000036357
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX60,186,814 - 60,313,049 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000069007   ⟹   ENSSSCP00000061996
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX60,186,814 - 60,313,064 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000073102   ⟹   ENSSSCP00000060208
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX60,186,814 - 60,313,039 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000086510   ⟹   ENSSSCP00000070459
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX60,186,814 - 60,313,054 (-)Ensembl
RefSeq Acc Id: XM_001928719   ⟹   XP_001928754
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X60,186,559 - 60,313,098 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021080711   ⟹   XP_020936370
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X60,186,559 - 60,313,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021080712   ⟹   XP_020936371
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X60,187,389 - 60,313,073 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_001928754   ⟸   XM_001928719
- Peptide Label: isoform X1
- UniProtKB: A0A286ZXE4 (UniProtKB/TrEMBL),   A0A4X1W260 (UniProtKB/TrEMBL),   A0A8D1KJH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020936370   ⟸   XM_021080711
- Peptide Label: isoform X2
- UniProtKB: A0A5G2QZY2 (UniProtKB/TrEMBL),   A0A8D2BQ20 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020936371   ⟸   XM_021080712
- Peptide Label: isoform X3
- UniProtKB: A0A4X1W1L3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000061996   ⟸   ENSSSCT00000069007
RefSeq Acc Id: ENSSSCP00000070459   ⟸   ENSSSCT00000086510
RefSeq Acc Id: ENSSSCP00000013220   ⟸   ENSSSCT00000013585
RefSeq Acc Id: ENSSSCP00000028898   ⟸   ENSSSCT00000036440
RefSeq Acc Id: ENSSSCP00000060208   ⟸   ENSSSCT00000073102
RefSeq Acc Id: ENSSSCP00000036357   ⟸   ENSSSCT00000038920
RefSeq Acc Id: ENSSSCP00000029568   ⟸   ENSSSCT00000033898
Protein Domains
ABC transmembrane type-1   ABC transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012424 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015051746 UniProtKB/TrEMBL
  ENSSSCG00025051463 UniProtKB/TrEMBL
  ENSSSCG00030037879 UniProtKB/TrEMBL
  ENSSSCG00035024698 UniProtKB/TrEMBL
  ENSSSCG00040065775 UniProtKB/TrEMBL
  ENSSSCG00045011703 UniProtKB/TrEMBL
  ENSSSCG00050055046 UniProtKB/TrEMBL
  ENSSSCG00055019076 UniProtKB/TrEMBL
  ENSSSCG00060060688 UniProtKB/TrEMBL
  ENSSSCG00065046652 UniProtKB/TrEMBL
  ENSSSCG00070028181 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000033898.3 UniProtKB/TrEMBL
  ENSSSCT00000036440.4 UniProtKB/TrEMBL
  ENSSSCT00000038920 ENTREZGENE
  ENSSSCT00000038920.3 UniProtKB/TrEMBL
  ENSSSCT00000069007.2 UniProtKB/TrEMBL
  ENSSSCT00000073102.2 UniProtKB/TrEMBL
  ENSSSCT00000086510 ENTREZGENE
  ENSSSCT00000086510.2 UniProtKB/TrEMBL
  ENSSSCT00015074327.1 UniProtKB/TrEMBL
  ENSSSCT00015074587.1 UniProtKB/TrEMBL
  ENSSSCT00025070652.1 UniProtKB/TrEMBL
  ENSSSCT00025070847.1 UniProtKB/TrEMBL
  ENSSSCT00025070963.1 UniProtKB/TrEMBL
  ENSSSCT00030053014.1 UniProtKB/TrEMBL
  ENSSSCT00035032525.1 UniProtKB/TrEMBL
  ENSSSCT00035032532.1 UniProtKB/TrEMBL
  ENSSSCT00035032540.1 UniProtKB/TrEMBL
  ENSSSCT00040091006.1 UniProtKB/TrEMBL
  ENSSSCT00045019920.1 UniProtKB/TrEMBL
  ENSSSCT00045019979.1 UniProtKB/TrEMBL
  ENSSSCT00045020009.1 UniProtKB/TrEMBL
  ENSSSCT00050075148.1 UniProtKB/TrEMBL
  ENSSSCT00055037614.1 UniProtKB/TrEMBL
  ENSSSCT00055037839.1 UniProtKB/TrEMBL
  ENSSSCT00055037969.1 UniProtKB/TrEMBL
  ENSSSCT00060082807.1 UniProtKB/TrEMBL
  ENSSSCT00060082903.1 UniProtKB/TrEMBL
  ENSSSCT00065063854.1 UniProtKB/TrEMBL
  ENSSSCT00065063862.1 UniProtKB/TrEMBL
  ENSSSCT00065063868.1 UniProtKB/TrEMBL
  ENSSSCT00070056522.1 UniProtKB/TrEMBL
  ENSSSCT00070056525.1 UniProtKB/TrEMBL
  ENSSSCT00070056531.1 UniProtKB/TrEMBL
  ENSSSCT00070056532.1 UniProtKB/TrEMBL
  ENSSSCT00070056540.1 UniProtKB/TrEMBL
  ENSSSCT00070056541.1 UniProtKB/TrEMBL
  ENSSSCT00070056544.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Type_I_exporter UniProtKB/TrEMBL
KEGG Report ssc:100157043 UniProtKB/TrEMBL
NCBI Gene ABCB7 ENTREZGENE
PANTHER IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR24221 UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90123 UniProtKB/TrEMBL
UniProt A0A286ZXE4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VW96_PIG UniProtKB/TrEMBL
  A0A4X1VWA9_PIG UniProtKB/TrEMBL
  A0A4X1W0V4_PIG UniProtKB/TrEMBL
  A0A4X1W1K3_PIG UniProtKB/TrEMBL
  A0A4X1W1L3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1W260 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1W3D5_PIG UniProtKB/TrEMBL
  A0A5G2QA28_PIG UniProtKB/TrEMBL
  A0A5G2QUZ8_PIG UniProtKB/TrEMBL
  A0A5G2QZY2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1KJH3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2BQ20 ENTREZGENE, UniProtKB/TrEMBL
  F1RPJ8_PIG UniProtKB/TrEMBL
  K7GNW3_PIG UniProtKB/TrEMBL
UniProt Secondary K7GM11 UniProtKB/TrEMBL
VGNC ID VGNC:97855 ENTREZGENE