RGS3 (regulator of G protein signaling 3) - Rat Genome Database

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Gene: RGS3 (regulator of G protein signaling 3) Sus scrofa
Analyze
Symbol: RGS3
Name: regulator of G protein signaling 3
RGD ID: 14059097
Description: INVOLVED IN negative regulation of signal transduction (inferred); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH bladder disease (ortholog); Experimental Liver Cirrhosis (ortholog); lesion of sciatic nerve (ortholog); FOUND IN nucleus (ortholog); plasma membrane (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of G-protein signaling 3; regulator of G-protein signaling 3 pseudogene
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1254,067,492 - 254,211,805 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11254,078,618 - 254,211,805 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21284,875,313 - 284,953,037 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (ISO)
plasma membrane  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RGS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1254,067,492 - 254,211,805 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11254,078,618 - 254,211,805 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21284,875,313 - 284,953,037 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RGS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389113,444,730 - 113,597,738 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9113,444,731 - 113,597,743 (+)EnsemblGRCh38hg38GRCh38
GRCh379116,207,010 - 116,360,018 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369115,246,832 - 115,399,839 (+)NCBINCBI36Build 36hg18NCBI36
Build 349113,435,753 - 113,439,571NCBI
Celera986,854,611 - 87,007,602 (+)NCBICelera
Cytogenetic Map9q32NCBI
HuRef985,813,933 - 85,966,662 (+)NCBIHuRef
CHM1_19116,353,638 - 116,506,463 (+)NCBICHM1_1
T2T-CHM13v2.09125,643,547 - 125,796,339 (+)NCBIT2T-CHM13v2.0
Rgs3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39462,478,079 - 62,621,256 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl462,478,084 - 62,622,238 (+)EnsemblGRCm39 Ensembl
GRCm38462,559,835 - 62,703,019 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl462,559,847 - 62,704,001 (+)EnsemblGRCm38mm10GRCm38
MGSCv37462,220,881 - 62,364,053 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36462,046,208 - 62,188,696 (+)NCBIMGSCv36mm8
Celera461,227,755 - 61,366,061 (+)NCBICelera
Cytogenetic Map4B3NCBI
cM Map433.19NCBI
Rgs3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8581,037,588 - 81,177,446 (+)NCBIGRCr8
mRatBN7.2576,022,038 - 76,161,895 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl576,022,001 - 76,161,894 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx578,478,060 - 78,561,409 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0580,295,183 - 80,378,540 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0580,270,680 - 80,354,040 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0578,429,017 - 78,567,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl578,428,669 - 78,567,288 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0582,550,757 - 82,690,343 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4579,624,388 - 79,709,035 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1579,629,500 - 79,714,147 (+)NCBI
Celera575,018,488 - 75,101,807 (+)NCBICelera
Cytogenetic Map5q24NCBI
Rgs3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541913,919,051 - 14,056,521 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541913,918,274 - 14,042,090 (-)NCBIChiLan1.0ChiLan1.0
RGS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21125,779,028 - 25,933,046 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1925,781,387 - 25,935,478 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0984,561,302 - 84,696,534 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19112,929,604 - 113,065,746 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9112,927,407 - 113,065,746 (+)Ensemblpanpan1.1panPan2
RGS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11167,781,832 - 67,878,153 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1167,781,962 - 67,920,075 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1166,186,531 - 66,324,166 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01168,906,019 - 69,044,294 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1168,923,206 - 69,044,285 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11167,424,053 - 67,562,277 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01167,455,234 - 67,593,195 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01168,210,062 - 68,330,325 (+)NCBIUU_Cfam_GSD_1.0
Rgs3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947183,085,781 - 183,161,654 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936559112,375 - 180,737 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11225,985,782 - 26,118,393 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1225,985,723 - 26,117,343 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603516,686,032 - 16,825,304 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476021,514,359 - 21,636,684 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RGS3
4150 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000006026   ⟹   ENSSSCP00000005876
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1254,078,730 - 254,156,329 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000006027   ⟹   ENSSSCP00000005877
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1254,208,149 - 254,211,805 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000050786   ⟹   ENSSSCP00000040088
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1254,193,209 - 254,211,795 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000066581   ⟹   ENSSSCP00000060778
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1254,078,648 - 254,211,802 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000073414   ⟹   ENSSSCP00000065436
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1254,114,698 - 254,211,097 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000075223   ⟹   ENSSSCP00000068913
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1254,067,492 - 254,156,329 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000086941   ⟹   ENSSSCP00000065395
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1254,097,794 - 254,156,329 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000089852   ⟹   ENSSSCP00000073701
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1254,114,698 - 254,211,097 (+)Ensembl
RefSeq Acc Id: XM_003480580   ⟹   XP_003480628
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11254,078,618 - 254,211,805 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003480628   ⟸   XM_003480580
- UniProtKB: A0A8D1RHD8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000065436   ⟸   ENSSSCT00000073414
Ensembl Acc Id: ENSSSCP00000068913   ⟸   ENSSSCT00000075223
Ensembl Acc Id: ENSSSCP00000073701   ⟸   ENSSSCT00000089852
Ensembl Acc Id: ENSSSCP00000040088   ⟸   ENSSSCT00000050786
Ensembl Acc Id: ENSSSCP00000005877   ⟸   ENSSSCT00000006027
Ensembl Acc Id: ENSSSCP00000005876   ⟸   ENSSSCT00000006026
Ensembl Acc Id: ENSSSCP00000060778   ⟸   ENSSSCT00000066581
Ensembl Acc Id: ENSSSCP00000065395   ⟸   ENSSSCT00000086941
Protein Domains
C2   PDZ   RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000005480 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00015021988 UniProtKB/TrEMBL
  ENSSSCG00025038695 UniProtKB/TrEMBL
  ENSSSCG00030007618 UniProtKB/TrEMBL
  ENSSSCG00040007811 UniProtKB/TrEMBL
  ENSSSCG00045028019 UniProtKB/TrEMBL
  ENSSSCG00050052198 UniProtKB/TrEMBL
  ENSSSCG00055022846 UniProtKB/TrEMBL
  ENSSSCG00060048630 UniProtKB/TrEMBL
  ENSSSCG00065019666 UniProtKB/TrEMBL
  ENSSSCG00070021230 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006026.4 UniProtKB/TrEMBL
  ENSSSCT00015029379.1 UniProtKB/TrEMBL
  ENSSSCT00015029464.1 UniProtKB/TrEMBL
  ENSSSCT00015029868.1 UniProtKB/TrEMBL
  ENSSSCT00015030066.1 UniProtKB/TrEMBL
  ENSSSCT00025052721.1 UniProtKB/TrEMBL
  ENSSSCT00025052925.1 UniProtKB/TrEMBL
  ENSSSCT00025053023.1 UniProtKB/TrEMBL
  ENSSSCT00025053111.1 UniProtKB/TrEMBL
  ENSSSCT00025053141.1 UniProtKB/TrEMBL
  ENSSSCT00030010226.1 UniProtKB/TrEMBL
  ENSSSCT00030010265.1 UniProtKB/TrEMBL
  ENSSSCT00030010294.1 UniProtKB/TrEMBL
  ENSSSCT00030010310.1 UniProtKB/TrEMBL
  ENSSSCT00030010345.1 UniProtKB/TrEMBL
  ENSSSCT00030010357.1 UniProtKB/TrEMBL
  ENSSSCT00040010245.1 UniProtKB/TrEMBL
  ENSSSCT00040010281.1 UniProtKB/TrEMBL
  ENSSSCT00040010294.1 UniProtKB/TrEMBL
  ENSSSCT00040010312.1 UniProtKB/TrEMBL
  ENSSSCT00040010339.1 UniProtKB/TrEMBL
  ENSSSCT00040010346.1 UniProtKB/TrEMBL
  ENSSSCT00040010370.1 UniProtKB/TrEMBL
  ENSSSCT00045047692.1 UniProtKB/TrEMBL
  ENSSSCT00045047785.1 UniProtKB/TrEMBL
  ENSSSCT00045048014.1 UniProtKB/TrEMBL
  ENSSSCT00045048224.1 UniProtKB/TrEMBL
  ENSSSCT00045048371.1 UniProtKB/TrEMBL
  ENSSSCT00045048549.1 UniProtKB/TrEMBL
  ENSSSCT00050071081.1 UniProtKB/TrEMBL
  ENSSSCT00050071089.1 UniProtKB/TrEMBL
  ENSSSCT00050071170.1 UniProtKB/TrEMBL
  ENSSSCT00055044934.1 UniProtKB/TrEMBL
  ENSSSCT00055045140.1 UniProtKB/TrEMBL
  ENSSSCT00055045354.1 UniProtKB/TrEMBL
  ENSSSCT00055045610.1 UniProtKB/TrEMBL
  ENSSSCT00055045783.1 UniProtKB/TrEMBL
  ENSSSCT00055046060.1 UniProtKB/TrEMBL
  ENSSSCT00055046341.1 UniProtKB/TrEMBL
  ENSSSCT00055046427.1 UniProtKB/TrEMBL
  ENSSSCT00055046496.1 UniProtKB/TrEMBL
  ENSSSCT00055046630.1 UniProtKB/TrEMBL
  ENSSSCT00060066058.1 UniProtKB/TrEMBL
  ENSSSCT00060066070.1 UniProtKB/TrEMBL
  ENSSSCT00060066095.1 UniProtKB/TrEMBL
  ENSSSCT00060066105.1 UniProtKB/TrEMBL
  ENSSSCT00060066112.1 UniProtKB/TrEMBL
  ENSSSCT00065026224.1 UniProtKB/TrEMBL
  ENSSSCT00065026225.1 UniProtKB/TrEMBL
  ENSSSCT00070042252.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  RGS_RGS3 UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
NCBI Gene RGS3 ENTREZGENE
PANTHER REGULATOR OF G PROTEIN SIGNALING UniProtKB/TrEMBL
  REGULATOR OF G-PROTEIN SIGNALING 3 UniProtKB/TrEMBL
  REGULATOR OF G-PROTEIN SIGNALING 3 UniProtKB/TrEMBL
  RGS DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48097 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A8D0HZQ7_PIG UniProtKB/TrEMBL
  A0A8D0I3I3_PIG UniProtKB/TrEMBL
  A0A8D0RVC3_PIG UniProtKB/TrEMBL
  A0A8D0VDF0_PIG UniProtKB/TrEMBL
  A0A8D0VDT6_PIG UniProtKB/TrEMBL
  A0A8D0VE46_PIG UniProtKB/TrEMBL
  A0A8D1DAA2_PIG UniProtKB/TrEMBL
  A0A8D1DAC7_PIG UniProtKB/TrEMBL
  A0A8D1IKR7_PIG UniProtKB/TrEMBL
  A0A8D1IQR6_PIG UniProtKB/TrEMBL
  A0A8D1L478_PIG UniProtKB/TrEMBL
  A0A8D1RGP9_PIG UniProtKB/TrEMBL
  A0A8D1RHD8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1RNY2_PIG UniProtKB/TrEMBL
  A0A8D1U963_PIG UniProtKB/TrEMBL
  A0A8D1U9I4_PIG UniProtKB/TrEMBL
  A0A8D1XWB1_PIG UniProtKB/TrEMBL
  F1SN86_PIG UniProtKB/TrEMBL
VGNC ID VGNC:103161 ENTREZGENE