Rgs3 (regulator of G protein signaling 3) - Rat Genome Database

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Gene: Rgs3 (regulator of G protein signaling 3) Chinchilla lanigera
Analyze
Symbol: Rgs3
Name: regulator of G protein signaling 3
RGD ID: 8839133
Description: PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH bladder disease (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN nucleus (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of G-protein signaling 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541913,919,051 - 14,056,521 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541913,918,274 - 14,042,090 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (ISO)
plasma membrane  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rgs3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541913,919,051 - 14,056,521 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541913,918,274 - 14,042,090 (-)NCBIChiLan1.0ChiLan1.0
RGS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389113,444,730 - 113,597,738 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9113,444,731 - 113,597,743 (+)EnsemblGRCh38hg38GRCh38
GRCh379116,207,010 - 116,360,018 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369115,246,832 - 115,399,839 (+)NCBINCBI36Build 36hg18NCBI36
Build 349113,435,753 - 113,439,571NCBI
Celera986,854,611 - 87,007,602 (+)NCBICelera
Cytogenetic Map9q32NCBI
HuRef985,813,933 - 85,966,662 (+)NCBIHuRef
CHM1_19116,353,638 - 116,506,463 (+)NCBICHM1_1
T2T-CHM13v2.09125,643,547 - 125,796,339 (+)NCBIT2T-CHM13v2.0
Rgs3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39462,478,079 - 62,621,256 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl462,478,084 - 62,622,238 (+)EnsemblGRCm39 Ensembl
GRCm38462,559,835 - 62,703,019 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl462,559,847 - 62,704,001 (+)EnsemblGRCm38mm10GRCm38
MGSCv37462,220,881 - 62,364,053 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36462,046,208 - 62,188,696 (+)NCBIMGSCv36mm8
Celera461,227,755 - 61,366,061 (+)NCBICelera
Cytogenetic Map4B3NCBI
cM Map433.19NCBI
Rgs3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8581,037,588 - 81,177,446 (+)NCBIGRCr8
mRatBN7.2576,022,038 - 76,161,895 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl576,022,001 - 76,161,894 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx578,478,060 - 78,561,409 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0580,295,183 - 80,378,540 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0580,270,680 - 80,354,040 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0578,429,017 - 78,567,281 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl578,428,669 - 78,567,288 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0582,550,757 - 82,690,343 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4579,624,388 - 79,709,035 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1579,629,500 - 79,714,147 (+)NCBI
Celera575,018,488 - 75,101,807 (+)NCBICelera
Cytogenetic Map5q24NCBI
RGS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21125,779,028 - 25,933,046 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1925,781,387 - 25,935,478 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0984,561,302 - 84,696,534 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19112,929,604 - 113,065,746 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9112,927,407 - 113,065,746 (+)Ensemblpanpan1.1panPan2
RGS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11167,781,832 - 67,878,153 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1167,781,962 - 67,920,075 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1166,186,531 - 66,324,166 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01168,906,019 - 69,044,294 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1168,923,206 - 69,044,285 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11167,424,053 - 67,562,277 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01167,455,234 - 67,593,195 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01168,210,062 - 68,330,325 (+)NCBIUU_Cfam_GSD_1.0
Rgs3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947183,085,781 - 183,161,654 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936559112,375 - 180,737 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1254,067,492 - 254,211,805 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11254,078,618 - 254,211,805 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21284,875,313 - 284,953,037 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RGS3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11225,985,782 - 26,118,393 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1225,985,723 - 26,117,343 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603516,686,032 - 16,825,304 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476021,514,359 - 21,636,684 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000015081   ⟹   ENSCLAP00000014922
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541913,919,051 - 14,007,957 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000015082   ⟹   ENSCLAP00000014923
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541913,968,380 - 14,040,741 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000015083   ⟹   ENSCLAP00000014924
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541913,971,292 - 14,056,521 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000015084   ⟹   ENSCLAP00000014925
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541913,971,292 - 14,053,926 (-)Ensembl
RefSeq Acc Id: XM_005382663   ⟹   XP_005382720
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,918,274 - 14,040,548 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005382665   ⟹   XP_005382722
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,918,274 - 14,008,046 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005382666   ⟹   XP_005382723
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,968,380 - 14,040,568 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005382668   ⟹   XP_005382725
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,918,274 - 13,950,556 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005382669   ⟹   XP_005382726
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,918,274 - 13,950,974 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005382670   ⟹   XP_005382727
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,918,274 - 13,950,352 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005382672   ⟹   XP_005382729
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,918,274 - 13,940,469 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005382673   ⟹   XP_005382730
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,968,380 - 14,008,070 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513122   ⟹   XP_013368576
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,918,274 - 14,042,090 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513124   ⟹   XP_013368578
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541913,918,274 - 13,922,113 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005382722   ⟸   XM_005382665
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VJM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005382720   ⟸   XM_005382663
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VJM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005382726   ⟸   XM_005382669
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005382725   ⟸   XM_005382668
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005382727   ⟸   XM_005382670
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005382729   ⟸   XM_005382672
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005382723   ⟸   XM_005382666
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VMB7 (UniProtKB/TrEMBL),   A0A8C2VHV8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005382730   ⟸   XM_005382673
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_013368576   ⟸   XM_013513122
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VJM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013368578   ⟸   XM_013513124
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: ENSCLAP00000014922   ⟸   ENSCLAT00000015081
RefSeq Acc Id: ENSCLAP00000014924   ⟸   ENSCLAT00000015083
RefSeq Acc Id: ENSCLAP00000014923   ⟸   ENSCLAT00000015082
RefSeq Acc Id: ENSCLAP00000014925   ⟸   ENSCLAT00000015084
Protein Domains
C2   PDZ   RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010293 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015081 ENTREZGENE
  ENSCLAT00000015081.1 UniProtKB/TrEMBL
  ENSCLAT00000015082 ENTREZGENE
  ENSCLAT00000015082.1 UniProtKB/TrEMBL
  ENSCLAT00000015083.1 UniProtKB/TrEMBL
  ENSCLAT00000015084.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  RGS_RGS3 UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
NCBI Gene Rgs3 ENTREZGENE
PANTHER REGULATOR OF G-PROTEIN SIGNALING 3 UniProtKB/TrEMBL
  REGULATOR OF G-PROTEIN SIGNALING 3 UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48097 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A8C2VHV8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VJM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VL70_CHILA UniProtKB/TrEMBL
  A0A8C2VMB7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-29 Rgs3  regulator of G protein signaling 3    regulator of G-protein signaling 3  Symbol and/or name change 5135510 APPROVED