MGAM2 (maltase-glucoamylase 2 (putative)) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: MGAM2 (maltase-glucoamylase 2 (putative)) Sus scrofa
Analyze
Symbol: MGAM2
Name: maltase-glucoamylase 2 (putative)
RGD ID: 14017493
Description: ENCODES a protein that exhibits alpha-glucosidase activity (inferred); carbohydrate binding (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN carbohydrate metabolic process (inferred); ASSOCIATED WITH Hirschsprung's disease (ortholog); FOUND IN membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable maltase-glucoamylase 2; putative maltase-glucoamylase-like protein FLJ16351
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,767,698 - 7,858,337 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,767,831 - 7,863,717 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2188,041,532 - 8,134,301 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MGAM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl187,767,698 - 7,858,337 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1187,767,831 - 7,863,717 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2188,041,532 - 8,134,301 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MGAM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387142,111,718 - 142,222,324 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7142,111,718 - 142,222,324 (+)EnsemblGRCh38hg38GRCh38
GRCh377141,811,518 - 141,922,124 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367141,458,018 - 141,490,252 (+)NCBINCBI36Build 36hg18NCBI36
Celera7136,589,043 - 136,621,282 (+)NCBICelera
Cytogenetic Map7q34NCBI
HuRef7136,106,676 - 136,138,931 (+)NCBIHuRef
CHM1_17141,745,780 - 141,778,014 (+)NCBICHM1_1
T2T-CHM13v2.07143,426,769 - 143,537,371 (+)NCBIT2T-CHM13v2.0
Mgam2-ps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39640,774,758 - 40,832,524 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl640,755,645 - 40,845,098 (+)EnsemblGRCm39 Ensembl
GRCm38640,797,824 - 40,855,590 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl640,778,711 - 40,868,164 (+)EnsemblGRCm38mm10GRCm38
MGSCv37640,736,940 - 40,818,163 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36640,716,548 - 40,797,771 (+)NCBIMGSCv36mm8
Celera640,773,037 - 40,854,305 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map618.82NCBI
Mgam2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554941,308,054 - 1,391,538 (-)NCBIChiLan1.0ChiLan1.0
MGAM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26178,891,070 - 179,004,778 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1730,901,325 - 31,015,033 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07134,033,704 - 134,146,212 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17146,504,572 - 146,616,397 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7146,509,175 - 146,616,397 (+)Ensemblpanpan1.1panPan2
MGAM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1167,053,433 - 7,119,396 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl167,034,970 - 7,114,587 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha167,892,122 - 7,978,446 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0166,954,369 - 7,040,704 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,956,012 - 7,036,119 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1166,907,862 - 6,994,262 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0166,749,205 - 6,836,473 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,817,874 - 6,904,208 (-)NCBIUU_Cfam_GSD_1.0
Mgam2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511813,203,525 - 13,285,059 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493697178,610 - 149,508 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493697178,610 - 167,061 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGAM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121110,843,718 - 110,951,341 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660727,544,863 - 7,654,404 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mgam2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476522,160,073 - 22,269,158 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476522,143,948 - 22,250,206 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MGAM2
4623 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8
Low 2 2 3 5 23 2 3 1
Below cutoff 2 2 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000017951   ⟹   ENSSSCP00000017469
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl187,767,698 - 7,855,921 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000052165   ⟹   ENSSSCP00000038364
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl187,767,698 - 7,858,337 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000086880   ⟹   ENSSSCP00000067760
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl187,767,698 - 7,855,921 (-)Ensembl
RefSeq Acc Id: XM_021079093   ⟹   XP_020934752
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1187,767,831 - 7,863,714 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021079094   ⟹   XP_020934753
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1187,767,831 - 7,863,717 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021079095   ⟹   XP_020934754
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1187,767,831 - 7,863,717 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020934752 (Get FASTA)   NCBI Sequence Viewer  
  XP_020934753 (Get FASTA)   NCBI Sequence Viewer  
  XP_020934754 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000017469.4
  ENSSSCP00000038364
  ENSSSCP00000038364.2
  ENSSSCP00000067760.1
Reference Protein Sequences
RefSeq Acc Id: XP_020934753   ⟸   XM_021079094
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020934754   ⟸   XM_021079095
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_020934752   ⟸   XM_021079093
- Peptide Label: isoform X1
- UniProtKB: A0A287A375 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000038364   ⟸   ENSSSCT00000052165
RefSeq Acc Id: ENSSSCP00000017469   ⟸   ENSSSCT00000017951
RefSeq Acc Id: ENSSSCP00000067760   ⟸   ENSSSCT00000086880
Protein Domains
P-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016487 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017951.4 UniProtKB/TrEMBL
  ENSSSCT00000052165 ENTREZGENE
  ENSSSCT00000052165.2 UniProtKB/TrEMBL
  ENSSSCT00000086880.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1180 UniProtKB/TrEMBL
  4.10.110.10 UniProtKB/TrEMBL
  Glycosidases UniProtKB/TrEMBL
  glycosyl hydrolase (family 31) UniProtKB/TrEMBL
InterPro Gal_mutarotase_sf_dom UniProtKB/TrEMBL
  Glyco_hydro_31 UniProtKB/TrEMBL
  Glyco_hydro_31_AS UniProtKB/TrEMBL
  Glyco_hydro_31_C UniProtKB/TrEMBL
  Glyco_hydro_31_N_dom UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
  P_trefoil_dom UniProtKB/TrEMBL
  P_trefoil_dom_sf UniProtKB/TrEMBL
NCBI Gene MGAM2 ENTREZGENE
PANTHER ALPHA-GLUCOSIDASE UniProtKB/TrEMBL
  P-TYPE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam Gal_mutarotas_2 UniProtKB/TrEMBL
  Glyco_hydro_31 UniProtKB/TrEMBL
  Glyco_hydro_31_3rd UniProtKB/TrEMBL
  Trefoil UniProtKB/TrEMBL
PROSITE GLYCOSYL_HYDROL_F31_1 UniProtKB/TrEMBL
  P_TREFOIL_2 UniProtKB/TrEMBL
SMART SM00018 UniProtKB/TrEMBL
Superfamily-SCOP Glycosyl hydrolase domain UniProtKB/TrEMBL
  SSF51445 UniProtKB/TrEMBL
  SSF57492 UniProtKB/TrEMBL
  SSF74650 UniProtKB/TrEMBL
UniProt A0A287A375 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QS51_PIG UniProtKB/TrEMBL
  F1SRR8_PIG UniProtKB/TrEMBL
VGNC ID VGNC:110312 ENTREZGENE