RCAN1 (regulator of calcineurin 1) - Rat Genome Database

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Gene: RCAN1 (regulator of calcineurin 1) Sus scrofa
Analyze
Symbol: RCAN1
Name: regulator of calcineurin 1
RGD ID: 14017175
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein phosphatase inhibitor activity (ortholog); INVOLVED IN calcineurin-NFAT signaling cascade (ortholog); locomotion involved in locomotory behavior (ortholog); negative regulation of smooth muscle cell differentiation (ortholog); PARTICIPATES IN calcineurin signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); autosomal dominant intellectual developmental disorder 7 (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol; resveratrol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: calcipressin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13198,102,098 - 198,205,629 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113198,106,256 - 198,205,727 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213207,934,802 - 208,034,246 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
nucleus  (IBA,IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:16504160   PMID:17145712   PMID:17407547   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RCAN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13198,102,098 - 198,205,629 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113198,106,256 - 198,205,727 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213207,934,802 - 208,034,246 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RCAN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382134,516,442 - 34,615,113 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2134,513,142 - 34,615,113 (-)EnsemblGRCh38hg38GRCh38
GRCh372135,888,740 - 35,987,412 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362134,810,652 - 34,909,252 (-)NCBINCBI36Build 36hg18NCBI36
Build 342134,810,655 - 34,821,131NCBI
Celera2121,088,350 - 21,186,950 (-)NCBICelera
Cytogenetic Map21q22.12ENTREZGENE
HuRef2121,367,653 - 21,466,258 (-)NCBIHuRef
CHM1_12135,451,030 - 35,549,660 (-)NCBICHM1_1
T2T-CHM13v2.02132,899,007 - 32,997,690 (-)NCBIT2T-CHM13v2.0
Rcan1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391692,188,839 - 92,263,057 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1692,188,841 - 92,267,755 (-)EnsemblGRCm39 Ensembl
GRCm381692,391,951 - 92,466,169 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1692,391,953 - 92,470,867 (-)EnsemblGRCm38mm10GRCm38
MGSCv371692,392,198 - 92,466,391 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361692,280,814 - 92,288,917 (-)NCBIMGSCv36mm8
Celera1693,474,521 - 93,548,716 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1653.6NCBI
Rcan1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81145,108,123 - 45,188,065 (-)NCBIGRCr8
mRatBN7.21131,622,208 - 31,702,150 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1131,622,210 - 31,702,045 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1140,316,701 - 40,326,773 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,988,158 - 32,998,230 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01132,146,929 - 32,157,070 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01132,539,689 - 32,620,274 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1132,539,683 - 32,550,539 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01136,145,269 - 36,224,657 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41132,386,576 - 32,408,850 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11132,442,819 - 32,465,093 (-)NCBI
Celera1131,275,905 - 31,284,458 (-)NCBICelera
Cytogenetic Map11q11NCBI
Rcan1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540733,873,383 - 33,951,498 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540733,873,427 - 33,951,762 (-)NCBIChiLan1.0ChiLan1.0
RCAN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22230,639,624 - 30,738,449 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12125,476,531 - 25,596,275 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02120,889,123 - 20,987,964 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12134,256,757 - 34,266,895 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2134,258,355 - 34,267,025 (-)Ensemblpanpan1.1panPan2
RCAN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13129,908,046 - 30,002,412 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3129,909,388 - 30,002,418 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3129,007,504 - 29,101,691 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03129,209,212 - 29,303,372 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3129,209,217 - 29,303,378 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13129,075,502 - 29,169,521 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03129,089,892 - 29,184,228 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03129,580,718 - 29,674,857 (-)NCBIUU_Cfam_GSD_1.0
Rcan1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497129,517,567 - 29,599,664 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365007,942,133 - 7,950,271 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365007,942,099 - 7,950,256 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RCAN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1278,561,212 - 78,658,023 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl278,562,795 - 78,571,498 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660546,377,519 - 6,475,296 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rcan1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474522,683,016 - 22,764,720 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474522,683,600 - 22,764,735 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RCAN1
5105 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000013182   ⟹   ENSSSCP00000012831
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13198,102,098 - 198,205,629 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000042623   ⟹   ENSSSCP00000034760
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13198,106,282 - 198,205,540 (-)Ensembl
RefSeq Acc Id: NM_001243913   ⟹   NP_001230842
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113198,106,256 - 198,116,543 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005657146   ⟹   XP_005657203
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113198,106,256 - 198,205,727 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005657203   ⟸   XM_005657146
- Peptide Label: isoform X1
- UniProtKB: A0A4X1TV21 (UniProtKB/TrEMBL),   F1SGX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230842   ⟸   NM_001243913
- UniProtKB: A0A8D1WPN6 (UniProtKB/TrEMBL),   A0A480UNP7 (UniProtKB/TrEMBL),   A0A286ZTF9 (UniProtKB/TrEMBL),   A0A8D0IU94 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000034760   ⟸   ENSSSCT00000042623
Ensembl Acc Id: ENSSSCP00000012831   ⟸   ENSSSCT00000013182


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000012050 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005019710 UniProtKB/TrEMBL
  ENSSSCG00015018923 UniProtKB/TrEMBL
  ENSSSCG00025011323 UniProtKB/TrEMBL
  ENSSSCG00030003458 UniProtKB/TrEMBL
  ENSSSCG00035029423 UniProtKB/TrEMBL
  ENSSSCG00040024270 UniProtKB/TrEMBL
  ENSSSCG00045022969 UniProtKB/TrEMBL
  ENSSSCG00050016599 UniProtKB/TrEMBL
  ENSSSCG00055024428 UniProtKB/TrEMBL
  ENSSSCG00060071932 UniProtKB/TrEMBL
  ENSSSCG00065029017 UniProtKB/TrEMBL
  ENSSSCG00070011916 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000013182 ENTREZGENE
  ENSSSCT00000013182.4 UniProtKB/TrEMBL
  ENSSSCT00000042623 ENTREZGENE
  ENSSSCT00000042623.3 UniProtKB/TrEMBL
  ENSSSCT00005031099.1 UniProtKB/TrEMBL
  ENSSSCT00015024999.1 UniProtKB/TrEMBL
  ENSSSCT00015025070.1 UniProtKB/TrEMBL
  ENSSSCT00025014859.1 UniProtKB/TrEMBL
  ENSSSCT00025014908.1 UniProtKB/TrEMBL
  ENSSSCT00030004530.1 UniProtKB/TrEMBL
  ENSSSCT00030004546.1 UniProtKB/TrEMBL
  ENSSSCT00030004573.1 UniProtKB/TrEMBL
  ENSSSCT00035038990.1 UniProtKB/TrEMBL
  ENSSSCT00035038998.1 UniProtKB/TrEMBL
  ENSSSCT00035039002.1 UniProtKB/TrEMBL
  ENSSSCT00040032460.1 UniProtKB/TrEMBL
  ENSSSCT00040032499.1 UniProtKB/TrEMBL
  ENSSSCT00040032548.1 UniProtKB/TrEMBL
  ENSSSCT00045039212.1 UniProtKB/TrEMBL
  ENSSSCT00045039264.1 UniProtKB/TrEMBL
  ENSSSCT00045039360.1 UniProtKB/TrEMBL
  ENSSSCT00050022626.1 UniProtKB/TrEMBL
  ENSSSCT00050022635.1 UniProtKB/TrEMBL
  ENSSSCT00050022644.1 UniProtKB/TrEMBL
  ENSSSCT00055048118.1 UniProtKB/TrEMBL
  ENSSSCT00055048172.1 UniProtKB/TrEMBL
  ENSSSCT00060098238.1 UniProtKB/TrEMBL
  ENSSSCT00060098253.1 UniProtKB/TrEMBL
  ENSSSCT00060098310.1 UniProtKB/TrEMBL
  ENSSSCT00065039146.1 UniProtKB/TrEMBL
  ENSSSCT00065039153.1 UniProtKB/TrEMBL
  ENSSSCT00065039165.1 UniProtKB/TrEMBL
  ENSSSCT00070023225.1 UniProtKB/TrEMBL
  ENSSSCT00070023238.1 UniProtKB/TrEMBL
  ENSSSCT00070023241.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Calcipressin UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RCAN1_RRM UniProtKB/TrEMBL
KEGG Report ssc:100511902 UniProtKB/TrEMBL
NCBI Gene RCAN1 ENTREZGENE
PANTHER PTHR10300 UniProtKB/TrEMBL
  PTHR10300:SF4 UniProtKB/TrEMBL
Pfam Calcipressin UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A286ZTF9 ENTREZGENE, UniProtKB/TrEMBL
  A0A480UNP7 ENTREZGENE
  A0A4X1TQ34_PIG UniProtKB/TrEMBL
  A0A4X1TV21 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0IU94 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WPN6 ENTREZGENE, UniProtKB/TrEMBL
  F1SGX6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A480UNP7 UniProtKB/TrEMBL
VGNC ID VGNC:92170 ENTREZGENE