CFC1B (cryptic, EGF-CFC family member 1B) - Rat Genome Database

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Gene: CFC1B (cryptic, EGF-CFC family member 1B) Sus scrofa
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Symbol: CFC1B
Name: cryptic, EGF-CFC family member 1B
RGD ID: 14002734
Description: INVOLVED IN anterior/posterior pattern specification (ortholog); atrial septum morphogenesis (ortholog); coronary vasculature development (ortholog); ASSOCIATED WITH dextro-looped transposition of the great arteries (ortholog); double outlet right ventricle (ortholog); Neurodevelopmental Disorders (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cripto, FRL-1, cryptic family 1B; cryptic family protein 1B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11556,943,183 - 56,951,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215156,796,746 - 156,838,845 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:20865782   PMID:30032202  


Genomics

Comparative Map Data
CFC1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11556,943,183 - 56,951,929 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215156,796,746 - 156,838,845 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CFC1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382130,521,222 - 130,528,603 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2130,521,197 - 130,528,604 (+)EnsemblGRCh38hg38GRCh38
GRCh372131,278,795 - 131,286,176 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362130,995,137 - 131,002,035 (+)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map2q21.1NCBI
HuRef2123,494,573 - 123,501,471 (-)NCBIHuRef
T2T-CHM13v2.02130,955,059 - 130,962,469 (+)NCBIT2T-CHM13v2.0
Cfc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39134,574,729 - 34,583,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl134,574,729 - 34,583,394 (+)EnsemblGRCm39 Ensembl
GRCm38134,535,648 - 34,544,311 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl134,535,648 - 34,544,313 (+)EnsemblGRCm38mm10GRCm38
MGSCv37134,592,493 - 34,601,156 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36134,480,194 - 34,488,857 (+)NCBIMGSCv36mm8
Celera134,300,622 - 34,309,253 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map113.34NCBI
Cfc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8944,234,997 - 44,247,846 (+)NCBIGRCr8
mRatBN7.2936,742,106 - 36,751,931 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl936,739,071 - 36,751,930 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx945,241,509 - 45,248,846 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0950,372,685 - 50,380,022 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0948,654,596 - 48,661,933 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0941,045,352 - 41,051,979 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl941,045,363 - 41,052,024 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0940,715,518 - 40,722,102 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4933,280,037 - 33,287,118 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera934,533,261 - 34,540,347 (+)NCBICelera
Cytogenetic Map9q21NCBI
CFC1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21344,953,766 - 44,962,222 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B44,968,741 - 44,977,173 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B29,354,004 - 29,362,161 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B131,440,871 - 131,448,310 (+)NCBIpanpan1.1PanPan1.1panPan2
LOC609557
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11920,318,937 - 20,384,369 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1920,622,155 - 20,687,786 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01921,635,233 - 21,700,948 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1921,690,527 - 21,700,978 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11920,274,928 - 20,339,946 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01920,565,378 - 20,602,313 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01921,578,101 - 21,643,757 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in CFC1B
132 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
1 11 3 1 2 1 11 1 3

Sequence


RefSeq Acc Id: XM_021075435   ⟹   XP_020931094
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11556,943,183 - 56,951,929 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020931094 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000017368
  ENSSSCP00000017368.5
RefSeq Acc Id: XP_020931094   ⟸   XM_021075435
- UniProtKB: F1SHY4 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
EGF-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016393 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017849 ENTREZGENE
  ENSSSCT00000017849.5 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro Cryptic/Cripto_CFC-dom UniProtKB/TrEMBL
  Dev_Signal_Modulators UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
NCBI Gene CFC1B ENTREZGENE
PANTHER CRYPTIC FAMILY PROTEIN 1B-RELATED UniProtKB/TrEMBL
  EGF-LIKE-DOMAIN, MULTIPLE 7, 8 UniProtKB/TrEMBL
Pfam CFC UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
UniProt F1SHY4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-13 CFC1B  cryptic, EGF-CFC family member 1B  CFC1B  cripto, FRL-1, cryptic family 1B  Symbol and/or name change 5135510 APPROVED