MTFR2 (mitochondrial fission regulator 2) - Rat Genome Database

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Gene: MTFR2 (mitochondrial fission regulator 2) Sus scrofa
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Symbol: MTFR2
Name: mitochondrial fission regulator 2
RGD ID: 13992666
Description: INVOLVED IN aerobic respiration (inferred); mitochondrial fission (inferred); mitochondrion organization (inferred); ASSOCIATED WITH Familial Behcet-Like Autoinflammatory Syndrome (ortholog); immunodeficiency 27A (ortholog); Peroxisome biogenesis disorder 9B (ortholog); FOUND IN mitochondrion (inferred)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DUF729 domain containing 1; FAM54A; family with sequence similarity 54, member A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl127,908,824 - 28,015,101 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1127,906,162 - 27,998,861 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2131,398,310 - 31,486,257 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MTFR2PigFamilial Behcet-Like Autoinflammatory Syndrome  ISOMTFR2 (Homo sapiens)8554872ClinVar Annotator: match by term: Autoinflammatory syndrome more ...ClinVarPMID:25741868
MTFR2Pigimmunodeficiency 27A  ISOMTFR2 (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 27AClinVarPMID:28492532
MTFR2PigPeroxisome biogenesis disorder 9B  ISOMTFR2 (Homo sapiens)8554872ClinVar Annotator: match by term: Peroxisome biogenesis disorder 9BClinVarPMID:12325024 more ...


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MTFR2Pigaerobic respiration involved_inIBAMGI:1914722 more ...150520179 GO_CentralGO_REF:0000033
MTFR2Pigaerobic respiration involved_inIEAUniRule:UR001693760150520179 UniProtGO_REF:0000104
MTFR2Pigaerobic respiration involved_inIEAUniProtKB:Q8VED8 and ensembl:ENSMUSP00000129315150520179 EnsemblGO_REF:0000107
MTFR2Pigmitochondrial fission involved_inIBAMGI:1919054 more ...150520179 GO_CentralGO_REF:0000033
MTFR2Pigmitochondrial fission involved_inIEAUniRule:UR001693760150520179 UniProtGO_REF:0000104
MTFR2Pigmitochondrial fission involved_inIEAUniProtKB:Q8VED8 and ensembl:ENSMUSP00000129315150520179 EnsemblGO_REF:0000107
MTFR2Pigmitochondrion organization involved_inIEAUniProtKB:Q8VED8 and ensembl:ENSMUSP00000129315150520179 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MTFR2Pigmitochondrion is_active_inIBAMGI:1919054 more ...150520179 GO_CentralGO_REF:0000033
MTFR2Pigmitochondrion located_inIEAUniProtKB-KW:KW-0496150520179 UniProtGO_REF:0000043
MTFR2Pigmitochondrion located_inIEAUniRule:UR001693760150520179 UniProtGO_REF:0000104
MTFR2Pigmitochondrion located_inIEAUniProtKB-SubCell:SL-0173150520179 UniProtGO_REF:0000044
MTFR2Pigmitochondrion located_inIEAUniProtKB:Q8VED8 and ensembl:ENSMUSP00000129315150520179 EnsemblGO_REF:0000107

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MTFR2Pigprotein binding enablesISOUniProtKB:P13196 more ...9068941 PMID:25416956IntActPMID:25416956

PMID:14681463   PMID:17145712   PMID:30032202  



MTFR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl127,908,824 - 28,015,101 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1127,906,162 - 27,998,861 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2131,398,310 - 31,486,257 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTFR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386136,231,034 - 136,250,311 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6136,231,024 - 136,250,335 (-)EnsemblGRCh38hg38GRCh38
GRCh376136,552,172 - 136,571,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366136,593,861 - 136,613,142 (-)NCBINCBI36Build 36hg18NCBI36
Build 346136,593,860 - 136,613,142NCBI
Celera6137,292,609 - 137,311,889 (-)NCBICelera
Cytogenetic Map6q23.3NCBI
HuRef6134,116,804 - 134,136,084 (-)NCBIHuRef
CHM1_16136,814,686 - 136,833,971 (-)NCBICHM1_1
T2T-CHM13v2.06137,419,143 - 137,438,419 (-)NCBIT2T-CHM13v2.0
Mtfr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391020,223,491 - 20,237,415 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1020,223,516 - 20,237,050 (+)EnsemblGRCm39 Ensembl
GRCm381020,344,653 - 20,361,669 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1020,347,770 - 20,361,304 (+)EnsemblGRCm38mm10GRCm38
MGSCv371020,067,625 - 20,081,475 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361020,037,241 - 20,050,735 (+)NCBIMGSCv36mm8
Celera1020,236,666 - 20,250,342 (+)NCBICelera
Cytogenetic Map10A3NCBI
cM Map109.75NCBI
Mtfr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8116,942,814 - 16,958,218 (+)NCBIGRCr8
mRatBN7.2115,123,232 - 15,138,632 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl115,070,894 - 15,148,832 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx114,877,372 - 14,892,479 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0120,879,304 - 20,894,408 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0115,103,132 - 15,118,478 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0115,834,779 - 15,850,424 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl115,782,477 - 15,860,624 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0117,379,823 - 17,394,566 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera113,553,856 - 13,569,459 (+)NCBICelera
Cytogenetic Map1p12NCBI
Mtfr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955439646,432 - 663,033 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955439643,289 - 662,921 (+)NCBIChiLan1.0ChiLan1.0
MTFR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25156,201,929 - 156,226,277 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16154,100,726 - 154,124,456 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06133,995,679 - 134,014,947 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16138,085,517 - 138,104,764 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6138,084,908 - 138,104,740 (-)Ensemblpanpan1.1panPan2
MTFR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1128,830,818 - 28,844,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl128,830,867 - 28,844,710 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha129,708,976 - 29,723,038 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0128,986,198 - 29,000,267 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl128,984,794 - 29,000,115 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1128,872,409 - 28,886,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0128,755,384 - 28,769,446 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0129,056,087 - 29,070,152 (-)NCBIUU_Cfam_GSD_1.0
Mtfr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946123,881,482 - 123,893,809 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365603,660,705 - 3,671,917 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365603,656,639 - 3,670,923 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTFR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11337,173,430 - 37,192,734 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1337,174,438 - 37,192,790 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660409,361,104 - 9,383,691 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtfr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248861,434,253 - 1,444,462 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248861,431,171 - 1,446,007 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in MTFR2
3158 total Variants



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 14 1 2 5 12 11 14 2 4 3



Ensembl Acc Id: ENSSSCT00000004603   ⟹   ENSSSCP00000004500
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl127,908,824 - 28,015,101 (+)Ensembl
RefSeq Acc Id: NM_001190176   ⟹   NP_001177105
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1127,908,789 - 27,923,634 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005654380   ⟹   XP_005654437
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1127,906,162 - 27,927,481 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013984860   ⟹   XP_013840314
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1127,906,162 - 27,998,861 (+)NCBI
Sequence:
RefSeq Acc Id: XP_013840314   ⟸   XM_013984860
- Peptide Label: isoform X1
- UniProtKB: F1S3R9 (UniProtKB/TrEMBL),   A0A8D1Y5F9 (UniProtKB/TrEMBL),   A0A480JPD4 (UniProtKB/TrEMBL),   A0A4X1VKM6 (UniProtKB/TrEMBL),   A0A8D0XBW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005654437   ⟸   XM_005654380
- Peptide Label: isoform X1
- UniProtKB: F1S3R9 (UniProtKB/TrEMBL),   A0A8D1Y5F9 (UniProtKB/TrEMBL),   A0A480JPD4 (UniProtKB/TrEMBL),   A0A4X1VKM6 (UniProtKB/TrEMBL),   A0A8D0XBW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001177105   ⟸   NM_001190176
- UniProtKB: A0A8D1ABJ1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000004500   ⟸   ENSSSCT00000004603



1 to 33 of 33 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSSCG00000004164 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015053795 UniProtKB/TrEMBL
  ENSSSCG00030053254 UniProtKB/TrEMBL
  ENSSSCG00035051236 UniProtKB/TrEMBL
  ENSSSCG00040017462 UniProtKB/TrEMBL
  ENSSSCG00050077120 UniProtKB/TrEMBL
  ENSSSCG00055024671 UniProtKB/TrEMBL
  ENSSSCG00065028315 UniProtKB/TrEMBL
  ENSSSCG00070024885 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004603 ENTREZGENE
  ENSSSCT00000004603.4 UniProtKB/TrEMBL
  ENSSSCT00015071641.1 UniProtKB/TrEMBL
  ENSSSCT00030074296.1 UniProtKB/TrEMBL
  ENSSSCT00035068242.1 UniProtKB/TrEMBL
  ENSSSCT00040023553.1 UniProtKB/TrEMBL
  ENSSSCT00050106113.1 UniProtKB/TrEMBL
  ENSSSCT00055048616.1 UniProtKB/TrEMBL
  ENSSSCT00065038185.1 UniProtKB/TrEMBL
  ENSSSCT00065038188.1 UniProtKB/TrEMBL
  ENSSSCT00070049746.1 UniProtKB/TrEMBL
InterPro Mtfr1 UniProtKB/TrEMBL
NCBI Gene MTFR2 ENTREZGENE
PANTHER MITOCHONDRIAL FISSION REGULATOR 2 UniProtKB/TrEMBL
  PTHR14215 UniProtKB/TrEMBL
Pfam Mito_fiss_reg UniProtKB/TrEMBL
UniProt A0A480JPD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VKM6 ENTREZGENE
  A0A8D0XBW4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1ABJ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Y5F9 ENTREZGENE, UniProtKB/TrEMBL
  F1S3R9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1VKM6 UniProtKB/TrEMBL
VGNC ID VGNC:90449 ENTREZGENE
1 to 33 of 33 rows