LAPTM4B (lysosomal protein transmembrane 4 beta) - Rat Genome Database

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Gene: LAPTM4B (lysosomal protein transmembrane 4 beta) Sus scrofa
Analyze
Symbol: LAPTM4B
Name: lysosomal protein transmembrane 4 beta
RGD ID: 13931252
Description: ENCODES a protein that exhibits ceramide binding (inferred); kinase binding (inferred); phosphatidylinositol bisphosphate binding (inferred); INVOLVED IN endosome organization (inferred); endosome transport via multivesicular body sorting pathway (inferred); negative regulation of lysosomal protein catabolic process (inferred); FOUND IN cell projection (inferred); early endosome (inferred); endomembrane system (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lysosomal-associated transmembrane protein 4B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl438,932,742 - 39,023,925 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1438,932,735 - 39,015,219 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2441,977,266 - 42,060,047 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LAPTM4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl438,932,742 - 39,023,925 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1438,932,735 - 39,015,219 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2441,977,266 - 42,060,047 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAPTM4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38897,775,788 - 97,853,013 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl897,775,057 - 97,853,013 (+)EnsemblGRCh38hg38GRCh38
GRCh37898,788,016 - 98,865,241 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36898,856,985 - 98,934,006 (+)NCBINCBI36Build 36hg18NCBI36
Build 34898,856,984 - 98,933,998NCBI
Celera894,973,714 - 95,050,765 (+)NCBICelera
Cytogenetic Map8q22.1NCBI
HuRef893,993,667 - 94,068,953 (+)NCBIHuRef
CHM1_1898,828,294 - 98,905,316 (+)NCBICHM1_1
T2T-CHM13v2.0898,901,267 - 98,978,513 (+)NCBIT2T-CHM13v2.0
Laptm4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391534,238,279 - 34,284,448 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1534,238,174 - 34,284,448 (+)EnsemblGRCm39 Ensembl
GRCm381534,238,026 - 34,284,295 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1534,238,028 - 34,284,302 (+)EnsemblGRCm38mm10GRCm38
MGSCv371534,167,781 - 34,214,050 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361534,182,615 - 34,228,884 (+)NCBIMGSCv36mm8
Celera1534,858,574 - 34,904,967 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1513.98NCBI
Laptm4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8767,319,438 - 67,362,547 (+)NCBIGRCr8
mRatBN7.2765,434,525 - 65,477,386 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl765,434,394 - 65,477,383 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx767,323,714 - 67,366,569 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0769,525,436 - 69,568,294 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0769,391,712 - 69,434,580 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0772,924,911 - 72,968,099 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl772,924,799 - 72,968,101 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0773,094,975 - 73,138,163 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4769,654,990 - 69,697,852 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1769,675,719 - 69,718,578 (+)NCBI
Celera762,539,514 - 62,582,361 (+)NCBICelera
Cytogenetic Map7q22NCBI
Laptm4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541713,574,721 - 13,625,313 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541713,574,493 - 13,625,669 (+)NCBIChiLan1.0ChiLan1.0
LAPTM4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27115,118,902 - 115,196,183 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1890,660,516 - 90,737,745 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0894,414,275 - 94,491,483 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1896,600,799 - 96,677,927 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl896,600,799 - 96,677,927 (+)Ensemblpanpan1.1panPan2
LAPTM4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11341,134 - 127,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1341,121 - 127,182 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1332,510 - 121,655 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.013189,696 - 275,803 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl13189,690 - 278,080 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11333,907 - 119,927 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.013141,792 - 227,784 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.013147,644 - 233,653 (+)NCBIUU_Cfam_GSD_1.0
Laptm4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530337,491,363 - 37,555,672 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647044,914,011 - 44,982,065 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647044,917,462 - 44,981,773 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAPTM4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1892,695,445 - 92,771,935 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603947,990,959 - 48,066,846 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Laptm4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247634,991,548 - 5,038,138 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247634,991,562 - 5,036,624 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LAPTM4B
3070 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000006674   ⟹   ENSSSCP00000006495
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl438,932,742 - 39,023,925 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000075100   ⟹   ENSSSCP00000060829
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl438,932,744 - 39,015,135 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000077864   ⟹   ENSSSCP00000073962
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl438,932,750 - 39,015,167 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000085396   ⟹   ENSSSCP00000068727
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl438,932,736 - 39,016,571 (-)Ensembl
RefSeq Acc Id: XM_005655356   ⟹   XP_005655413
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1438,932,735 - 39,015,219 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005655413   ⟸   XM_005655356
- UniProtKB: A0A480K595 (UniProtKB/TrEMBL),   A0A4X1U108 (UniProtKB/TrEMBL),   A0A8D0PJZ4 (UniProtKB/TrEMBL),   F1S0L9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000006495   ⟸   ENSSSCT00000006674
Ensembl Acc Id: ENSSSCP00000060829   ⟸   ENSSSCT00000075100
Ensembl Acc Id: ENSSSCP00000068727   ⟸   ENSSSCT00000085396
Ensembl Acc Id: ENSSSCP00000073962   ⟸   ENSSSCT00000077864


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006083 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015065281 UniProtKB/TrEMBL
  ENSSSCG00025070730 UniProtKB/TrEMBL
  ENSSSCG00035058821 UniProtKB/TrEMBL
  ENSSSCG00040013661 UniProtKB/TrEMBL
  ENSSSCG00045031670 UniProtKB/TrEMBL
  ENSSSCG00055021401 UniProtKB/TrEMBL
  ENSSSCG00060072455 UniProtKB/TrEMBL
  ENSSSCG00065055072 UniProtKB/TrEMBL
  ENSSSCG00070013264 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006674.4 UniProtKB/TrEMBL
  ENSSSCT00000075100.1 UniProtKB/TrEMBL
  ENSSSCT00000077864 ENTREZGENE
  ENSSSCT00000077864.1 UniProtKB/TrEMBL
  ENSSSCT00015087351.1 UniProtKB/TrEMBL
  ENSSSCT00015087387.1 UniProtKB/TrEMBL
  ENSSSCT00015087427.1 UniProtKB/TrEMBL
  ENSSSCT00015087490.1 UniProtKB/TrEMBL
  ENSSSCT00025097114.1 UniProtKB/TrEMBL
  ENSSSCT00025097232.1 UniProtKB/TrEMBL
  ENSSSCT00025097346.1 UniProtKB/TrEMBL
  ENSSSCT00035078740.1 UniProtKB/TrEMBL
  ENSSSCT00035078742.1 UniProtKB/TrEMBL
  ENSSSCT00035078747.1 UniProtKB/TrEMBL
  ENSSSCT00035078752.1 UniProtKB/TrEMBL
  ENSSSCT00040018182.1 UniProtKB/TrEMBL
  ENSSSCT00040018189.1 UniProtKB/TrEMBL
  ENSSSCT00040018202.1 UniProtKB/TrEMBL
  ENSSSCT00040018221.1 UniProtKB/TrEMBL
  ENSSSCT00045053994.1 UniProtKB/TrEMBL
  ENSSSCT00045054065.1 UniProtKB/TrEMBL
  ENSSSCT00045054133.1 UniProtKB/TrEMBL
  ENSSSCT00055042020.1 UniProtKB/TrEMBL
  ENSSSCT00055042097.1 UniProtKB/TrEMBL
  ENSSSCT00055042184.1 UniProtKB/TrEMBL
  ENSSSCT00060099029.1 UniProtKB/TrEMBL
  ENSSSCT00060099048.1 UniProtKB/TrEMBL
  ENSSSCT00060099058.1 UniProtKB/TrEMBL
  ENSSSCT00065075387.1 UniProtKB/TrEMBL
  ENSSSCT00065075395.1 UniProtKB/TrEMBL
  ENSSSCT00065075398.1 UniProtKB/TrEMBL
  ENSSSCT00070025865.1 UniProtKB/TrEMBL
InterPro LAPTM4/5 UniProtKB/TrEMBL
  LAPTM_transporter UniProtKB/TrEMBL
NCBI Gene LAPTM4B ENTREZGENE
PANTHER LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN UniProtKB/TrEMBL
  PTHR12479:SF6 UniProtKB/TrEMBL
Pfam Mtp UniProtKB/TrEMBL
UniProt A0A480K595 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U108 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QFM1_PIG UniProtKB/TrEMBL
  A0A8D0PJZ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TEC1_PIG UniProtKB/TrEMBL
  A0A8D0V089_PIG UniProtKB/TrEMBL
  A0A8D1RHU0_PIG UniProtKB/TrEMBL
  A0A8D1WPF2_PIG UniProtKB/TrEMBL
  F1S0L9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:89637 ENTREZGENE