RPAP2 (RNA polymerase II associated protein 2) - Rat Genome Database

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Gene: RPAP2 (RNA polymerase II associated protein 2) Sus scrofa
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Symbol: RPAP2
Name: RNA polymerase II associated protein 2
RGD ID: 13906249
Description: ENCODES a protein that exhibits calmodulin-dependent protein phosphatase activity (inferred); histone H2AXS140 phosphatase activity (inferred); MAP kinase serine/threonine phosphatase activity (inferred); INVOLVED IN chromatin remodeling (inferred); PERK-mediated unfolded protein response (inferred); regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH Diamond-Blackfan anemia (ortholog); severe congenital neutropenia 2 (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4124,690,317 - 124,773,887 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14124,691,655 - 124,773,914 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24136,360,271 - 136,442,510 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
RPAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4124,690,317 - 124,773,887 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14124,691,655 - 124,773,914 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24136,360,271 - 136,442,510 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RPAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38192,299,059 - 92,402,056 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl192,299,059 - 92,402,056 (+)EnsemblGRCh38hg38GRCh38
GRCh37192,764,616 - 92,867,613 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,537,193 - 92,626,317 (+)NCBINCBI36Build 36hg18NCBI36
Celera191,010,952 - 91,106,077 (+)NCBICelera
Cytogenetic Map1p22.1NCBI
HuRef190,884,969 - 90,974,879 (+)NCBIHuRef
CHM1_1192,879,299 - 92,968,461 (+)NCBICHM1_1
T2T-CHM13v2.0192,143,968 - 92,246,943 (+)NCBIT2T-CHM13v2.0
Rpap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395107,745,239 - 107,809,719 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5107,745,239 - 107,809,704 (+)EnsemblGRCm39 Ensembl
GRCm385107,597,373 - 107,661,853 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5107,597,373 - 107,661,838 (+)EnsemblGRCm38mm10GRCm38
MGSCv375108,026,399 - 108,090,857 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365107,838,037 - 107,902,138 (+)NCBIMGSCv36mm8
Celera5104,709,740 - 104,774,242 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map552.23NCBI
Rpap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8142,253,966 - 2,332,251 (-)NCBIGRCr8
mRatBN7.2142,109,044 - 2,187,343 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl142,109,053 - 2,187,350 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx141,987,484 - 2,065,871 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0143,289,301 - 3,367,686 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0141,985,869 - 2,064,466 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0143,125,595 - 3,204,590 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl143,124,622 - 3,204,588 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0143,126,061 - 3,205,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,664,860 - 2,744,461 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,664,860 - 2,744,461 (-)NCBI
Celera142,127,947 - 2,207,709 (-)NCBICelera
Cytogenetic Map14p22NCBI
Rpap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554232,101,780 - 2,195,390 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554232,062,163 - 2,195,351 (-)NCBIChiLan1.0ChiLan1.0
RPAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21134,634,757 - 134,722,997 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11133,774,458 - 133,877,685 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0194,962,964 - 95,102,307 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,701,765 - 93,790,323 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,701,765 - 93,790,323 (+)Ensemblpanpan1.1panPan2
RPAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1656,564,310 - 56,644,382 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha659,264,179 - 59,343,537 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0656,941,722 - 57,021,916 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl656,873,999 - 57,021,872 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1656,621,561 - 56,701,635 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0656,600,482 - 56,680,323 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0657,060,629 - 57,140,708 (-)NCBIUU_Cfam_GSD_1.0
Rpap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058102,169,688 - 102,255,994 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365376,692,000 - 6,778,275 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12040,863,401 - 40,950,981 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2040,863,719 - 40,950,879 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603377,056,891 - 77,145,495 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247425,338,997 - 5,434,936 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RPAP2
2994 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000007559   ⟹   ENSSSCP00000007359
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4124,690,309 - 124,773,887 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000038115   ⟹   ENSSSCP00000039251
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4124,719,333 - 124,773,861 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000042637   ⟹   ENSSSCP00000038558
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4124,691,658 - 124,773,843 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000043396   ⟹   ENSSSCP00000036550
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4124,691,806 - 124,773,847 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000046391   ⟹   ENSSSCP00000040970
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4124,717,612 - 124,773,861 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000067382   ⟹   ENSSSCP00000059842
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4124,690,317 - 124,773,887 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000082015   ⟹   ENSSSCP00000072173
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl4124,690,317 - 124,773,887 (-)Ensembl
RefSeq Acc Id: XM_003125906   ⟹   XP_003125954
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.14124,691,655 - 124,773,914 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003125954 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000038558.2
  ENSSSCP00000059842
  ENSSSCP00000059842.1
  ENSSSCP00000072173.1
  ENSSSCP00065038595.1
  ENSSSCP00070022763.1
RefSeq Acc Id: XP_003125954   ⟸   XM_003125906
- UniProtKB: A0A481APA8 (UniProtKB/TrEMBL),   A0A480LYN8 (UniProtKB/TrEMBL),   A0A480M400 (UniProtKB/TrEMBL),   A0A4X1U4K3 (UniProtKB/TrEMBL),   A0A8D1ZMQ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000038558   ⟸   ENSSSCT00000042637
Ensembl Acc Id: ENSSSCP00000040970   ⟸   ENSSSCT00000046391
Ensembl Acc Id: ENSSSCP00000007359   ⟸   ENSSSCT00000007559
Ensembl Acc Id: ENSSSCP00000039251   ⟸   ENSSSCT00000038115
Ensembl Acc Id: ENSSSCP00000072173   ⟸   ENSSSCT00000082015
Ensembl Acc Id: ENSSSCP00000059842   ⟸   ENSSSCT00000067382
Ensembl Acc Id: ENSSSCP00000036550   ⟸   ENSSSCT00000043396
Protein Domains
RTR1-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006903 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00065064257 UniProtKB/TrEMBL
  ENSSSCG00070013949 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000042637.2 UniProtKB/TrEMBL
  ENSSSCT00000067382 ENTREZGENE
  ENSSSCT00000067382.2 UniProtKB/TrEMBL
  ENSSSCT00000082015.2 UniProtKB/TrEMBL
  ENSSSCT00065088212.1 UniProtKB/TrEMBL
  ENSSSCT00070027370.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.820 UniProtKB/TrEMBL
InterPro Rtr1/RPAP2 UniProtKB/TrEMBL
  Rtr1/RPAP2_dom UniProtKB/TrEMBL
  Rtr1/RPAP2_sf UniProtKB/TrEMBL
NCBI Gene RPAP2 ENTREZGENE
PANTHER PTHR14732 UniProtKB/TrEMBL
  RNA POLYMERASE II SUBUNIT B1 CTD PHOSPHATASE RPAP2-RELATED UniProtKB/TrEMBL
Pfam RPAP2_Rtr1 UniProtKB/TrEMBL
PROSITE ZF_RTR1 UniProtKB/TrEMBL
UniProt A0A287A3M8_PIG UniProtKB/TrEMBL
  A0A480LYN8 ENTREZGENE, UniProtKB/TrEMBL
  A0A480M400 ENTREZGENE, UniProtKB/TrEMBL
  A0A481APA8 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U4K3 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2R4N4_PIG UniProtKB/TrEMBL
  A0A8D1ZMQ4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:92418 ENTREZGENE