CARMIL3 (capping protein regulator and myosin 1 linker 3) - Rat Genome Database

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Gene: CARMIL3 (capping protein regulator and myosin 1 linker 3) Sus scrofa
Analyze
Symbol: CARMIL3
Name: capping protein regulator and myosin 1 linker 3
RGD ID: 13849808
Description: INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); lysinuric protein intolerance (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: capping protein, Arp2/3 and myosin-I linker protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,222,528 - 75,241,242 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,222,528 - 75,241,243 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,492,975 - 80,511,400 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CARMIL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,222,528 - 75,241,242 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,222,528 - 75,241,243 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,492,975 - 80,511,400 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CARMIL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,052,009 - 24,069,729 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,052,009 - 24,069,729 (+)EnsemblGRCh38hg38GRCh38
GRCh371424,521,218 - 24,538,938 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,591,046 - 23,608,777 (+)NCBINCBI36Build 36hg18NCBI36
Celera144,385,685 - 4,403,416 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef144,636,144 - 4,653,872 (+)NCBIHuRef
CHM1_11424,519,882 - 24,537,614 (+)NCBICHM1_1
T2T-CHM13v2.01418,250,326 - 18,268,045 (+)NCBIT2T-CHM13v2.0
Carmil3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,728,108 - 55,745,729 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,728,108 - 55,745,729 (+)EnsemblGRCm39 Ensembl
GRCm381455,490,651 - 55,508,272 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,490,651 - 55,508,272 (+)EnsemblGRCm38mm10GRCm38
MGSCv371456,109,930 - 56,127,101 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,445,164 - 54,462,335 (+)NCBIMGSCv36mm8
Celera1453,296,005 - 53,313,185 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Carmil3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,948,228 - 32,965,829 (+)NCBIGRCr8
mRatBN7.21528,978,440 - 28,995,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,979,007 - 28,996,225 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,824,712 - 30,841,566 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,971,920 - 31,988,774 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,214,268 - 30,231,120 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,167,146 - 34,184,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,167,945 - 34,184,799 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,057,562 - 38,075,771 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,622,020 - 33,639,257 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,645,651 - 33,654,958 (+)NCBI
Celera1528,555,021 - 28,571,875 (+)NCBICelera
Cytogenetic Map15p13NCBI
Carmil3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,324,474 - 36,340,931 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,324,141 - 36,341,648 (-)NCBIChiLan1.0ChiLan1.0
CARMIL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,407,638 - 25,425,860 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,624,130 - 24,642,560 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,830,041 - 4,847,897 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,954,274 - 22,971,981 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,954,274 - 22,971,981 (+)Ensemblpanpan1.1panPan2
CARMIL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,059,154 - 4,076,385 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,059,133 - 4,076,396 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,981,155 - 3,998,261 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,169,943 - 4,187,054 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,169,881 - 4,187,065 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,860,706 - 3,877,810 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,922,469 - 3,939,569 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,184,546 - 4,201,662 (+)NCBIUU_Cfam_GSD_1.0
Carmil3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,908,398 - 35,925,866 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722464,240 - 480,590 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722463,791 - 480,594 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CARMIL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,034,790 - 1,053,169 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,035,947 - 1,052,844 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,717,257 - 12,735,362 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Carmil3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,459,756 - 8,477,287 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,460,032 - 8,477,298 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CARMIL3
210 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1
Low 3 22 2
Below cutoff 7 4 5 1 2 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000002251   ⟹   ENSSSCP00000002199
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl775,222,528 - 75,241,242 (-)Ensembl
RefSeq Acc Id: XM_021099222   ⟹   XP_020954881
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1775,222,528 - 75,241,243 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020954881   ⟸   XM_021099222
- UniProtKB: A0A4X1SKP8 (UniProtKB/TrEMBL),   A0A8D1TRQ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000002199   ⟸   ENSSSCT00000002251
Protein Domains
CARMIL C-terminal   CARMIL pleckstrin homology


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002012 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025074553 UniProtKB/TrEMBL
  ENSSSCG00035059379 UniProtKB/TrEMBL
  ENSSSCG00040075672 UniProtKB/TrEMBL
  ENSSSCG00045006431 UniProtKB/TrEMBL
  ENSSSCG00050077906 UniProtKB/TrEMBL
  ENSSSCG00055010225 UniProtKB/TrEMBL
  ENSSSCG00060007051 UniProtKB/TrEMBL
  ENSSSCG00065064402 UniProtKB/TrEMBL
  ENSSSCG00070001709 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000002251 ENTREZGENE
  ENSSSCT00000002251.5 UniProtKB/TrEMBL
  ENSSSCT00025102751.1 UniProtKB/TrEMBL
  ENSSSCT00025103010.1 UniProtKB/TrEMBL
  ENSSSCT00035079534.1 UniProtKB/TrEMBL
  ENSSSCT00035079542.1 UniProtKB/TrEMBL
  ENSSSCT00040105076.1 UniProtKB/TrEMBL
  ENSSSCT00040105082.1 UniProtKB/TrEMBL
  ENSSSCT00045010704.1 UniProtKB/TrEMBL
  ENSSSCT00045010731.1 UniProtKB/TrEMBL
  ENSSSCT00050107229.1 UniProtKB/TrEMBL
  ENSSSCT00050107258.1 UniProtKB/TrEMBL
  ENSSSCT00055020026.1 UniProtKB/TrEMBL
  ENSSSCT00055020095.1 UniProtKB/TrEMBL
  ENSSSCT00060008992.1 UniProtKB/TrEMBL
  ENSSSCT00060008999.1 UniProtKB/TrEMBL
  ENSSSCT00065088388.1 UniProtKB/TrEMBL
  ENSSSCT00065088400.1 UniProtKB/TrEMBL
  ENSSSCT00070003231.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro CARMIL_C UniProtKB/TrEMBL
  CARMIL_PH UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
NCBI Gene CARMIL3 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT, ISOFORM F-RELATED UniProtKB/TrEMBL
  PTHR24112:SF43 UniProtKB/TrEMBL
Pfam Carm_PH UniProtKB/TrEMBL
  CARMIL_C UniProtKB/TrEMBL
  LRR_6 UniProtKB/TrEMBL
SMART LRR_RI UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A0A4X1SKP8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TF22_PIG UniProtKB/TrEMBL
  A0A8D1Q973_PIG UniProtKB/TrEMBL
  A0A8D1TRQ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1ZSQ6_PIG UniProtKB/TrEMBL
  F1SGL5_PIG UniProtKB/TrEMBL
VGNC ID VGNC:86194 ENTREZGENE