Carmil3 (capping protein regulator and myosin 1 linker 3) - Rat Genome Database

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Gene: Carmil3 (capping protein regulator and myosin 1 linker 3) Ictidomys tridecemlineatus
Analyze
Symbol: Carmil3
Name: capping protein regulator and myosin 1 linker 3
RGD ID: 12546026
Description: INVOLVED IN cell migration (inferred); regulation of Arp2/3 complex-mediated actin nucleation (inferred); regulation of postsynapse assembly (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); lysinuric protein intolerance (ortholog); polycystic ovary syndrome (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: capping protein regulator and myosin 1 linker 3, transcript variant X1; capping protein regulator and myosin 1 linker 3, transcript variant X2; capping protein regulator and myosin 1 linker 3, transcript variant X3; capping protein regulator and myosin 1 linker 3, transcript variant X4; capping protein, Arp2/3 and myosin-I linker protein 3; leucine-rich repeat-containing protein 16B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,908,398 - 35,925,866 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722464,240 - 480,590 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722463,791 - 480,594 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Carmil3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,908,398 - 35,925,866 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722464,240 - 480,590 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722463,791 - 480,594 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CARMIL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,052,009 - 24,069,729 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1424,052,009 - 24,069,729 (+)EnsemblGRCh38hg38GRCh38
GRCh371424,521,218 - 24,538,938 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,591,046 - 23,608,777 (+)NCBINCBI36Build 36hg18NCBI36
Celera144,385,685 - 4,403,416 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef144,636,144 - 4,653,872 (+)NCBIHuRef
CHM1_11424,519,882 - 24,537,614 (+)NCBICHM1_1
T2T-CHM13v2.01418,250,326 - 18,268,045 (+)NCBIT2T-CHM13v2.0
Carmil3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,728,108 - 55,745,729 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,728,108 - 55,745,729 (+)EnsemblGRCm39 Ensembl
GRCm381455,490,651 - 55,508,272 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,490,651 - 55,508,272 (+)EnsemblGRCm38mm10GRCm38
MGSCv371456,109,930 - 56,127,101 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,445,164 - 54,462,335 (+)NCBIMGSCv36mm8
Celera1453,296,005 - 53,313,185 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Carmil3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,948,228 - 32,965,829 (+)NCBIGRCr8
mRatBN7.21528,978,440 - 28,995,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,979,007 - 28,996,225 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,824,712 - 30,841,566 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,971,920 - 31,988,774 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01530,214,268 - 30,231,120 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01534,167,146 - 34,184,799 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,167,945 - 34,184,799 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,057,562 - 38,075,771 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,622,020 - 33,639,257 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,645,651 - 33,654,958 (+)NCBI
Celera1528,555,021 - 28,571,875 (+)NCBICelera
Cytogenetic Map15p13NCBI
Carmil3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,324,474 - 36,340,931 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,324,141 - 36,341,648 (-)NCBIChiLan1.0ChiLan1.0
CARMIL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21525,407,638 - 25,425,860 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,624,130 - 24,642,560 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,830,041 - 4,847,897 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,954,274 - 22,971,981 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,954,274 - 22,971,981 (+)Ensemblpanpan1.1panPan2
CARMIL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,059,154 - 4,076,385 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,059,133 - 4,076,396 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,981,155 - 3,998,261 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,169,943 - 4,187,054 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,169,881 - 4,187,065 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,860,706 - 3,877,810 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,922,469 - 3,939,569 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,184,546 - 4,201,662 (+)NCBIUU_Cfam_GSD_1.0
CARMIL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,222,528 - 75,241,242 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,222,528 - 75,241,243 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,492,975 - 80,511,400 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CARMIL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,034,790 - 1,053,169 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,035,947 - 1,052,844 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,717,257 - 12,735,362 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Carmil3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,459,756 - 8,477,287 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,460,032 - 8,477,298 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000007519   ⟹   ENSSTOP00000006719
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936722464,240 - 480,590 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000043228   ⟹   ENSSTOP00000029465
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936722464,240 - 479,819 (-)Ensembl
RefSeq Acc Id: XM_005338746   ⟹   XP_005338803
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864035,908,398 - 35,925,058 (+)NCBI
SpeTri2.0NW_004936722463,934 - 480,594 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735565   ⟹   XP_021591240
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864035,908,402 - 35,925,866 (+)NCBI
SpeTri2.0NW_004936722463,791 - 480,590 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735566   ⟹   XP_021591241
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864035,908,402 - 35,925,866 (+)NCBI
SpeTri2.0NW_004936722463,791 - 480,590 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735567   ⟹   XP_021591242
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864035,908,402 - 35,925,866 (+)NCBI
SpeTri2.0NW_004936722463,791 - 480,590 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040275674   ⟹   XP_040131608
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864035,908,402 - 35,925,866 (+)NCBI
RefSeq Acc Id: XM_040275675   ⟹   XP_040131609
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864035,908,402 - 35,925,866 (+)NCBI
RefSeq Acc Id: XP_005338803   ⟸   XM_005338746
- Peptide Label: isoform X6
- UniProtKB: A0A287D7E2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591242   ⟸   XM_021735567
- Peptide Label: isoform X5
- UniProtKB: A0A287D7E2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591241   ⟸   XM_021735566
- Peptide Label: isoform X3
- UniProtKB: I3M9W5 (UniProtKB/TrEMBL),   A0A287D7E2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591240   ⟸   XM_021735565
- Peptide Label: isoform X2
- UniProtKB: A0A287D7E2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040131608   ⟸   XM_040275674
- Peptide Label: isoform X1
- UniProtKB: A0A287D7E2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131609   ⟸   XM_040275675
- Peptide Label: isoform X4
- UniProtKB: A0A287D7E2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000006719   ⟸   ENSSTOT00000007519
Ensembl Acc Id: ENSSTOP00000029465   ⟸   ENSSTOT00000043228
Protein Domains
CARMIL C-terminal   CARMIL pleckstrin homology


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000007478 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007519.3 UniProtKB/TrEMBL
  ENSSTOT00000043228.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro CARMIL_C UniProtKB/TrEMBL
  CARMIL_PH UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PP1-Reg/Actin-Interact_Protein UniProtKB/TrEMBL
NCBI Gene Carmil3 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT, ISOFORM F-RELATED UniProtKB/TrEMBL
  PTHR24112:SF43 UniProtKB/TrEMBL
Pfam Carm_PH UniProtKB/TrEMBL
  CARMIL_C UniProtKB/TrEMBL
  LRR_6 UniProtKB/TrEMBL
SMART LRR_RI UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A0A287D7E2 ENTREZGENE, UniProtKB/TrEMBL
  I3M9W5 ENTREZGENE, UniProtKB/TrEMBL