SIGLEC11 (sialic acid binding Ig like lectin 11) - Rat Genome Database

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Gene: SIGLEC11 (sialic acid binding Ig like lectin 11) Homo sapiens
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Symbol: SIGLEC11
Name: sialic acid binding Ig like lectin 11
RGD ID: 1354413
HGNC Page HGNC:15622
Description: Enables phosphatase binding activity and sialic acid binding activity. Predicted to be involved in several processes, including negative regulation of calcium-mediated signaling; negative regulation of inflammatory response to wounding; and regulation of B cell proliferation. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: sialic acid binding Ig-like lectin 11; sialic acid-binding Ig-like lectin 11; sialic acid-binding lectin 11; siglec-11
RGD Orthologs
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,948,985 - 49,961,172 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,948,985 - 49,961,172 (-)EnsemblGRCh38hg38GRCh38
GRCh371950,452,242 - 50,464,429 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,144,062 - 55,156,241 (-)NCBINCBI36Build 36hg18NCBI36
Build 341955,144,065 - 55,156,241NCBI
Celera1947,321,746 - 47,333,926 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,828,490 - 46,840,654 (-)NCBIHuRef
CHM1_11950,454,096 - 50,466,275 (-)NCBICHM1_1
T2T-CHM13v2.01952,949,097 - 52,961,282 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (HEP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
Additional References at PubMed
PMID:11986327   PMID:12975309   PMID:16151003   PMID:18629938   PMID:20203208   PMID:20237496   PMID:21467073   PMID:21873635   PMID:25320078   PMID:28100677   PMID:32845322  


Genomics

Comparative Map Data
SIGLEC11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,948,985 - 49,961,172 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,948,985 - 49,961,172 (-)EnsemblGRCh38hg38GRCh38
GRCh371950,452,242 - 50,464,429 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,144,062 - 55,156,241 (-)NCBINCBI36Build 36hg18NCBI36
Build 341955,144,065 - 55,156,241NCBI
Celera1947,321,746 - 47,333,926 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,828,490 - 46,840,654 (-)NCBIHuRef
CHM1_11950,454,096 - 50,466,275 (-)NCBICHM1_1
T2T-CHM13v2.01952,949,097 - 52,961,282 (-)NCBIT2T-CHM13v2.0
Siglecg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39743,057,623 - 43,067,773 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl743,057,628 - 43,067,782 (+)EnsemblGRCm39 Ensembl
GRCm38743,408,192 - 43,418,349 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl743,408,204 - 43,418,358 (+)EnsemblGRCm38mm10GRCm38
MGSCv37750,663,650 - 50,673,719 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36743,276,188 - 43,286,267 (+)NCBIMGSCv36mm8
Celera738,874,487 - 38,884,555 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map728.25NCBI
SIGLEC11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22056,052,437 - 56,084,432 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,980,786 - 58,005,470 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,961,548 - 46,974,158 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,877,036 - 55,888,804 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,877,079 - 55,888,804 (-)Ensemblpanpan1.1panPan2
LOC484343
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,532,181 - 105,575,278 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1105,532,620 - 105,541,325 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1105,105,196 - 105,153,837 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01106,041,812 - 106,090,652 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1106,042,185 - 106,051,468 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11105,713,835 - 105,762,320 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,355,119 - 105,403,592 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,149,985 - 106,198,714 (+)NCBIUU_Cfam_GSD_1.0
SIGLEC10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1658,466,741 - 58,474,972 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2651,715,163 - 51,723,586 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SIGLEC11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1643,094,327 - 43,111,183 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607323,076,696 - 23,089,644 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in SIGLEC11
83 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.33-13.43(chr19:49907832-58557889)x3 copy number gain See cases [RCV000052925] Chr19:49907832..58557889 [GRCh38]
Chr19:50411089..59069256 [GRCh37]
Chr19:55102901..63761068 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47908540-58539965)x3 copy number gain See cases [RCV000052914] Chr19:47908540..58539965 [GRCh38]
Chr19:48411797..59051332 [GRCh37]
Chr19:53103609..63743144 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh38/hg38 19q13.33-13.43(chr19:47929575-58572206)x3 copy number gain See cases [RCV000052915] Chr19:47929575..58572206 [GRCh38]
Chr19:48432832..59083573 [GRCh37]
Chr19:53124644..63775385 [NCBI36]
Chr19:19q13.33-13.43		 pathogenic
GRCh37/hg19 19q13.33(chr19:50391979-50665993)x3 copy number gain See cases [RCV000446903] Chr19:50391979..50665993 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1573A>G (p.Ser525Gly) single nucleotide variant not specified [RCV004292036] Chr19:49958361 [GRCh38]
Chr19:50461618 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1615G>A (p.Gly539Arg) single nucleotide variant not specified [RCV004333105] Chr19:49958319 [GRCh38]
Chr19:50461576 [GRCh37]
Chr19:19q13.33		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q13.33(chr19:50445773-50453317)x1 copy number loss not provided [RCV000740202] Chr19:50445773..50453317 [GRCh37]
Chr19:19q13.33		 benign
NM_052884.3(SIGLEC11):c.1094C>G (p.Ala365Gly) single nucleotide variant not provided [RCV000949431] Chr19:49959041 [GRCh38]
Chr19:50462298 [GRCh37]
Chr19:19q13.33		 benign
NM_052884.3(SIGLEC11):c.793G>T (p.Ala265Ser) single nucleotide variant not provided [RCV000949432] Chr19:49959773 [GRCh38]
Chr19:50463030 [GRCh37]
Chr19:19q13.33		 benign
NM_052884.3(SIGLEC11):c.1456C>G (p.Arg486Gly) single nucleotide variant not provided [RCV000967535] Chr19:49958478 [GRCh38]
Chr19:50461735 [GRCh37]
Chr19:19q13.33		 benign
NM_052884.3(SIGLEC11):c.789G>A (p.Thr263=) single nucleotide variant not provided [RCV000947991] Chr19:49959777 [GRCh38]
Chr19:50463034 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.779A>G (p.His260Arg) single nucleotide variant not provided [RCV000947992] Chr19:49959787 [GRCh38]
Chr19:50463044 [GRCh37]
Chr19:19q13.33		 benign
NM_052884.3(SIGLEC11):c.1058-8C>T single nucleotide variant not provided [RCV000905327] Chr19:49959085 [GRCh38]
Chr19:50462342 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.469A>C (p.Lys157Gln) single nucleotide variant not provided [RCV000947993] Chr19:49960413 [GRCh38]
Chr19:50463670 [GRCh37]
Chr19:19q13.33		 benign
NM_052884.3(SIGLEC11):c.515C>T (p.Pro172Leu) single nucleotide variant not specified [RCV004293742] Chr19:49960367 [GRCh38]
Chr19:50463624 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1055A>T (p.Gln352Leu) single nucleotide variant not specified [RCV004300255] Chr19:49959362 [GRCh38]
Chr19:50462619 [GRCh37]
Chr19:19q13.33		 uncertain significance
GRCh37/hg19 19q13.33(chr19:49600909-51366070)x3 copy number gain not provided [RCV000847250] Chr19:49600909..51366070 [GRCh37]
Chr19:19q13.33		 uncertain significance
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3 copy number gain not provided [RCV001007050] Chr19:44738088..53621561 [GRCh37]
Chr19:19q13.31-13.42		 pathogenic
NM_052884.3(SIGLEC11):c.1794G>A (p.Glu598=) single nucleotide variant not provided [RCV000905268] Chr19:49951927 [GRCh38]
Chr19:50455184 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.1776C>T (p.Arg592=) single nucleotide variant not provided [RCV000954519] Chr19:49951945 [GRCh38]
Chr19:50455202 [GRCh37]
Chr19:19q13.33		 benign
GRCh37/hg19 19q13.32-13.42(chr19:47939842-54626871) copy number gain not provided [RCV001249294] Chr19:47939842..54626871 [GRCh37]
Chr19:19q13.32-13.42		 not provided
GRCh37/hg19 19q13.33-13.43(chr19:48463931-57095254)x3 copy number gain not provided [RCV001259944] Chr19:48463931..57095254 [GRCh37]
Chr19:19q13.33-13.43		 pathogenic
NM_052884.3(SIGLEC11):c.1371A>C (p.Pro457=) single nucleotide variant not provided [RCV004809202] Chr19:49958563 [GRCh38]
Chr19:50461820 [GRCh37]
Chr19:19q13.33		 likely benign
GRCh37/hg19 19q13.33(chr19:50355646-50552140) copy number gain not specified [RCV002052690] Chr19:50355646..50552140 [GRCh37]
Chr19:19q13.33		 uncertain significance
GRCh37/hg19 19q13.33-13.41(chr19:49911081-53127438) copy number gain not specified [RCV002052689] Chr19:49911081..53127438 [GRCh37]
Chr19:19q13.33-13.41		 likely pathogenic
NC_000019.9:g.(?_48618906)_(50921204_?)dup duplication Developmental and epileptic encephalopathy, 12 [RCV001939968]|not provided [RCV001916178] Chr19:48618906..50921204 [GRCh37]
Chr19:19q13.33		 uncertain significance
NC_000019.9:g.(?_50411496)_(50766697_?)dup duplication not provided [RCV003122710] Chr19:50411496..50766697 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.299G>A (p.Arg100Gln) single nucleotide variant not specified [RCV004322703] Chr19:49960713 [GRCh38]
Chr19:50463970 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1072C>G (p.Leu358Val) single nucleotide variant not specified [RCV004199543] Chr19:49959063 [GRCh38]
Chr19:50462320 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1343C>T (p.Ser448Phe) single nucleotide variant not specified [RCV004189771] Chr19:49958663 [GRCh38]
Chr19:50461920 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.361G>A (p.Ala121Thr) single nucleotide variant not specified [RCV004184916] Chr19:49960651 [GRCh38]
Chr19:50463908 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1819C>A (p.Pro607Thr) single nucleotide variant not specified [RCV004111670] Chr19:49951902 [GRCh38]
Chr19:50455159 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.284T>C (p.Val95Ala) single nucleotide variant not specified [RCV004081169] Chr19:49960728 [GRCh38]
Chr19:50463985 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1860C>G (p.Ser620Arg) single nucleotide variant not specified [RCV004213154] Chr19:49950207 [GRCh38]
Chr19:50453464 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1111G>A (p.Glu371Lys) single nucleotide variant not specified [RCV004111050] Chr19:49958895 [GRCh38]
Chr19:50462152 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1708G>A (p.Ala570Thr) single nucleotide variant not specified [RCV004092112] Chr19:49952338 [GRCh38]
Chr19:50455595 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.2018T>G (p.Ile673Ser) single nucleotide variant not specified [RCV004206574] Chr19:49950049 [GRCh38]
Chr19:50453306 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1448C>G (p.Pro483Arg) single nucleotide variant not specified [RCV004209619] Chr19:49958486 [GRCh38]
Chr19:50461743 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1664A>G (p.His555Arg) single nucleotide variant not specified [RCV004118732] Chr19:49952382 [GRCh38]
Chr19:50455639 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.727G>A (p.Val243Ile) single nucleotide variant not specified [RCV004098945] Chr19:49960155 [GRCh38]
Chr19:50463412 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.790T>A (p.Ser264Thr) single nucleotide variant not specified [RCV004154382] Chr19:49959776 [GRCh38]
Chr19:50463033 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.64G>A (p.Val22Met) single nucleotide variant not specified [RCV004075875] Chr19:49961018 [GRCh38]
Chr19:50464275 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.1973C>T (p.Ala658Val) single nucleotide variant not specified [RCV004202962] Chr19:49950094 [GRCh38]
Chr19:50453351 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1214G>A (p.Arg405Gln) single nucleotide variant not specified [RCV004225793] Chr19:49958792 [GRCh38]
Chr19:50462049 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.1304C>T (p.Thr435Ile) single nucleotide variant not specified [RCV004085764] Chr19:49958702 [GRCh38]
Chr19:50461959 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1126G>A (p.Gly376Ser) single nucleotide variant not specified [RCV004212707] Chr19:49958880 [GRCh38]
Chr19:50462137 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1741G>A (p.Val581Ile) single nucleotide variant not specified [RCV004223534] Chr19:49952305 [GRCh38]
Chr19:50455562 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.1457G>C (p.Arg486Pro) single nucleotide variant not specified [RCV004225045] Chr19:49958477 [GRCh38]
Chr19:50461734 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1281A>T (p.Gln427His) single nucleotide variant not specified [RCV004144656] Chr19:49958725 [GRCh38]
Chr19:50461982 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1510G>A (p.Glu504Lys) single nucleotide variant not specified [RCV004170587] Chr19:49958424 [GRCh38]
Chr19:50461681 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.991C>T (p.Arg331Cys) single nucleotide variant not specified [RCV004100154] Chr19:49959426 [GRCh38]
Chr19:50462683 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.514C>G (p.Pro172Ala) single nucleotide variant not specified [RCV004119050] Chr19:49960368 [GRCh38]
Chr19:50463625 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1139C>T (p.Pro380Leu) single nucleotide variant not specified [RCV004182531] Chr19:49958867 [GRCh38]
Chr19:50462124 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1516A>T (p.Thr506Ser) single nucleotide variant not specified [RCV004131673] Chr19:49958418 [GRCh38]
Chr19:50461675 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.154G>A (p.Val52Met) single nucleotide variant not specified [RCV004079653] Chr19:49960858 [GRCh38]
Chr19:50464115 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.103A>G (p.Ser35Gly) single nucleotide variant not specified [RCV004274970] Chr19:49960909 [GRCh38]
Chr19:50464166 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.965G>C (p.Arg322Pro) single nucleotide variant not specified [RCV004254379] Chr19:49959452 [GRCh38]
Chr19:50462709 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.974G>A (p.Arg325Lys) single nucleotide variant not specified [RCV004254380] Chr19:49959443 [GRCh38]
Chr19:50462700 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.1120G>A (p.Gly374Arg) single nucleotide variant not specified [RCV004253904] Chr19:49958886 [GRCh38]
Chr19:50462143 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.1531G>A (p.Gly511Arg) single nucleotide variant not specified [RCV004290959] Chr19:49958403 [GRCh38]
Chr19:50461660 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1892C>G (p.Thr631Ser) single nucleotide variant not specified [RCV004347542] Chr19:49950175 [GRCh38]
Chr19:50453432 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.317C>T (p.Thr106Ile) single nucleotide variant not specified [RCV004362055] Chr19:49960695 [GRCh38]
Chr19:50463952 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1304C>G (p.Thr435Ser) single nucleotide variant not specified [RCV004334683] Chr19:49958702 [GRCh38]
Chr19:50461959 [GRCh37]
Chr19:19q13.33		 uncertain significance
GRCh37/hg19 19q13.33-13.43(chr19:49625130-57647352)x3 copy number gain not provided [RCV003485200] Chr19:49625130..57647352 [GRCh37]
Chr19:19q13.33-13.43		 likely pathogenic
NM_052884.3(SIGLEC11):c.1275C>T (p.Pro425=) single nucleotide variant not provided [RCV003415371] Chr19:49958731 [GRCh38]
Chr19:50461988 [GRCh37]
Chr19:19q13.33		 likely benign
GRCh37/hg19 19q13.33-13.41(chr19:48905537-51614930)x3 copy number gain not specified [RCV003986127] Chr19:48905537..51614930 [GRCh37]
Chr19:19q13.33-13.41		 likely pathogenic
NM_052884.3(SIGLEC11):c.1125C>A (p.Asn375Lys) single nucleotide variant not specified [RCV004453561] Chr19:49958881 [GRCh38]
Chr19:50462138 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.324T>A (p.Asp108Glu) single nucleotide variant not specified [RCV004453576] Chr19:49960688 [GRCh38]
Chr19:50463945 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.676C>T (p.Leu226Phe) single nucleotide variant not specified [RCV004453579] Chr19:49960206 [GRCh38]
Chr19:50463463 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1316A>G (p.Gln439Arg) single nucleotide variant not specified [RCV004453565] Chr19:49958690 [GRCh38]
Chr19:50461947 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1562A>C (p.His521Pro) single nucleotide variant not specified [RCV004453567] Chr19:49958372 [GRCh38]
Chr19:50461629 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.230G>A (p.Arg77Gln) single nucleotide variant not specified [RCV004453574] Chr19:49960782 [GRCh38]
Chr19:50464039 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.415G>A (p.Val139Met) single nucleotide variant not specified [RCV004453578] Chr19:49960597 [GRCh38]
Chr19:50463854 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.737G>A (p.Arg246His) single nucleotide variant not specified [RCV004453580] Chr19:49960145 [GRCh38]
Chr19:50463402 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.851G>A (p.Arg284Gln) single nucleotide variant not specified [RCV004453581] Chr19:49959566 [GRCh38]
Chr19:50462823 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1223A>G (p.Gln408Arg) single nucleotide variant not specified [RCV004453562] Chr19:49958783 [GRCh38]
Chr19:50462040 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1367C>T (p.Pro456Leu) single nucleotide variant not specified [RCV004453566] Chr19:49958567 [GRCh38]
Chr19:50461824 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1610T>C (p.Val537Ala) single nucleotide variant not specified [RCV004453569] Chr19:49958324 [GRCh38]
Chr19:50461581 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1852G>A (p.Ala618Thr) single nucleotide variant not specified [RCV004453572] Chr19:49950215 [GRCh38]
Chr19:50453472 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.178C>T (p.Arg60Trp) single nucleotide variant not specified [RCV004453571] Chr19:49960834 [GRCh38]
Chr19:50464091 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.992G>A (p.Arg331His) single nucleotide variant not specified [RCV004453582] Chr19:49959425 [GRCh38]
Chr19:50462682 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.125T>G (p.Val42Gly) single nucleotide variant not specified [RCV004453563] Chr19:49960887 [GRCh38]
Chr19:50464144 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1291G>A (p.Glu431Lys) single nucleotide variant not specified [RCV004453564] Chr19:49958715 [GRCh38]
Chr19:50461972 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1877C>T (p.Pro626Leu) single nucleotide variant not specified [RCV004453573] Chr19:49950190 [GRCh38]
Chr19:50453447 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1093G>A (p.Ala365Thr) single nucleotide variant not specified [RCV004453560] Chr19:49959042 [GRCh38]
Chr19:50462299 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1579G>A (p.Gly527Ser) single nucleotide variant not specified [RCV004453568] Chr19:49958355 [GRCh38]
Chr19:50461612 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.290T>C (p.Met97Thr) single nucleotide variant not specified [RCV004453575] Chr19:49960722 [GRCh38]
Chr19:50463979 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.373G>A (p.Asp125Asn) single nucleotide variant not specified [RCV004453577] Chr19:49960639 [GRCh38]
Chr19:50463896 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.9G>A (p.Pro3=) single nucleotide variant not specified [RCV004453583] Chr19:49961073 [GRCh38]
Chr19:50464330 [GRCh37]
Chr19:19q13.33		 likely benign
NM_052884.3(SIGLEC11):c.154G>C (p.Val52Leu) single nucleotide variant not specified [RCV004676418] Chr19:49960858 [GRCh38]
Chr19:50464115 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.68T>C (p.Leu23Pro) single nucleotide variant not specified [RCV004669814] Chr19:49961014 [GRCh38]
Chr19:50464271 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1357G>C (p.Val453Leu) single nucleotide variant not specified [RCV004669815] Chr19:49958649 [GRCh38]
Chr19:50461906 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.2042G>A (p.Gly681Asp) single nucleotide variant not specified [RCV004669816] Chr19:49950025 [GRCh38]
Chr19:50453282 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1417T>C (p.Cys473Arg) single nucleotide variant not specified [RCV004669817] Chr19:49958517 [GRCh38]
Chr19:50461774 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1339G>A (p.Val447Ile) single nucleotide variant not specified [RCV004669818] Chr19:49958667 [GRCh38]
Chr19:50461924 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1702G>A (p.Gly568Ser) single nucleotide variant not specified [RCV004669819] Chr19:49952344 [GRCh38]
Chr19:50455601 [GRCh37]
Chr19:19q13.33		 uncertain significance
NM_052884.3(SIGLEC11):c.1118T>G (p.Leu373Arg) single nucleotide variant not specified [RCV004669820] Chr19:49958888 [GRCh38]
Chr19:50462145 [GRCh37]
Chr19:19q13.33		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1237
Count of miRNA genes:523
Interacting mature miRNAs:582
Transcripts:ENST00000426296, ENST00000426971, ENST00000447370
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
597303656GWAS1399730_HAlzheimer disease QTL GWAS1399730 (human)5e-09Alzheimer disease194995006049950061Human
597340252GWAS1436326_HAlzheimer disease QTL GWAS1436326 (human)0.000004Alzheimer disease194995006049950061Human
597138511GWAS1234585_Hplatelet measurement QTL GWAS1234585 (human)7e-13platelet measurementplatelet measurement (CMO:0000921)194995109149951092Human
597069391GWAS1165465_Hlung carcinoma QTL GWAS1165465 (human)0.000005lung carcinoma194995429449954295Human
596966382GWAS1085901_HAlzheimer disease QTL GWAS1085901 (human)0.000007Alzheimer disease194995006049950061Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human
597268564GWAS1364638_HAlzheimer disease QTL GWAS1364638 (human)0.000007Alzheimer disease194995006049950061Human

Markers in Region
D7S3207  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map7q36UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map8p11UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map8p21UniSTS
Cytogenetic Map13q12.11UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map9q33.2UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map4p13UniSTS
Cytogenetic Map3p21.1-p14.2UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map2p24.2UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map10p12.31UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map18q11.1UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map2q31.2-q33.1UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1203 2356 2708 2216 4719 1707 2241 3 614 1511 454 2116 6679 5982 33 3628 785 1667 1522 166

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_030323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_052884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005258476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005258477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054319699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_243888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB072038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC011452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF337818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY358135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000426296   ⟹   ENSP00000407387
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,949,670 - 49,958,458 (-)Ensembl
Ensembl Acc Id: ENST00000426971   ⟹   ENSP00000398891
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,949,300 - 49,961,081 (-)Ensembl
Ensembl Acc Id: ENST00000447370   ⟹   ENSP00000412361
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1949,948,985 - 49,961,172 (-)Ensembl
RefSeq Acc Id: NM_001135163   ⟹   NP_001128635
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,948,993 - 49,961,172 (-)NCBI
GRCh371950,452,250 - 50,464,439 (-)NCBI
Celera1947,321,746 - 47,333,926 (-)RGD
HuRef1946,828,490 - 46,840,654 (-)ENTREZGENE
CHM1_11950,454,096 - 50,466,275 (-)NCBI
T2T-CHM13v2.01952,949,105 - 52,961,282 (-)NCBI
Sequence:
RefSeq Acc Id: NM_052884   ⟹   NP_443116
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,948,985 - 49,961,172 (-)NCBI
GRCh371950,452,250 - 50,464,439 (-)NCBI
Build 361955,144,062 - 55,156,241 (-)NCBI Archive
Celera1947,321,746 - 47,333,926 (-)RGD
HuRef1946,828,490 - 46,840,654 (-)ENTREZGENE
CHM1_11950,454,096 - 50,466,275 (-)NCBI
T2T-CHM13v2.01952,949,097 - 52,961,282 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005258476   ⟹   XP_005258533
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,948,985 - 49,961,172 (-)NCBI
GRCh371950,452,250 - 50,464,439 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005258477   ⟹   XP_005258534
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,951,890 - 49,961,172 (-)NCBI
GRCh371950,452,250 - 50,464,439 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047438122   ⟹   XP_047294078
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,951,889 - 49,961,172 (-)NCBI
RefSeq Acc Id: XM_054319697   ⟹   XP_054175672
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,949,097 - 52,961,282 (-)NCBI
RefSeq Acc Id: XM_054319698   ⟹   XP_054175673
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,952,001 - 52,961,282 (-)NCBI
RefSeq Acc Id: XM_054319699   ⟹   XP_054175674
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01952,952,002 - 52,961,282 (-)NCBI
RefSeq Acc Id: NP_443116   ⟸   NM_052884
- Peptide Label: isoform 1 precursor
- UniProtKB: Q96RL6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001128635   ⟸   NM_001135163
- Peptide Label: isoform 2 precursor
- UniProtKB: Q96RL6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005258533   ⟸   XM_005258476
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005258534   ⟸   XM_005258477
- Peptide Label: isoform X3
- UniProtKB: I1VSB5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000407387   ⟸   ENST00000426296
Ensembl Acc Id: ENSP00000398891   ⟸   ENST00000426971
Ensembl Acc Id: ENSP00000412361   ⟸   ENST00000447370
RefSeq Acc Id: XP_047294078   ⟸   XM_047438122
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054175672   ⟸   XM_054319697
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054175673   ⟸   XM_054319698
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054175674   ⟸   XM_054319699
- Peptide Label: isoform X3
- UniProtKB: I1VSB5 (UniProtKB/TrEMBL)
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q96RL6-F1-model_v2 AlphaFold Q96RL6 1-698 view protein structure

Promoters
RGD ID:13205225
Promoter ID:EPDNEW_H26193
Type:initiation region
Name:SIGLEC11_2
Description:sialic acid binding Ig like lectin 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26194  EPDNEW_H26195  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,952,337 - 49,952,397EPDNEW
RGD ID:13205227
Promoter ID:EPDNEW_H26194
Type:initiation region
Name:SIGLEC11_3
Description:sialic acid binding Ig like lectin 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26193  EPDNEW_H26195  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,958,391 - 49,958,451EPDNEW
RGD ID:13205229
Promoter ID:EPDNEW_H26195
Type:initiation region
Name:SIGLEC11_1
Description:sialic acid binding Ig like lectin 11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26193  EPDNEW_H26194  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381949,961,083 - 49,961,143EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:15622 AgrOrtholog
COSMIC SIGLEC11 COSMIC
Ensembl Genes ENSG00000161640 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000426296.1 UniProtKB/TrEMBL
  ENST00000426971 ENTREZGENE
  ENST00000426971.2 UniProtKB/Swiss-Prot
  ENST00000447370 ENTREZGENE
  ENST00000447370.6 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000161640 GTEx
HGNC ID HGNC:15622 ENTREZGENE
Human Proteome Map SIGLEC11 Human Proteome Map
InterPro Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig/MHC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIGLEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:114132 UniProtKB/Swiss-Prot
NCBI Gene 114132 ENTREZGENE
OMIM 607157 OMIM
PANTHER SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SIALIC ACID-BINDING IG-LIKE LECTIN 11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA38005 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_MHC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Immunoglobulin UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt H7C2S0_HUMAN UniProtKB/TrEMBL
  I1VSB5 ENTREZGENE, UniProtKB/TrEMBL
  Q96RL6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-26 SIGLEC11  sialic acid binding Ig like lectin 11    sialic acid binding Ig-like lectin 11  Symbol and/or name change 5135510 APPROVED