Abcb5 (ATP binding cassette subfamily B member 5)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Abcb5 (ATP binding cassette subfamily B member 5) Rattus norvegicus

Analyze

Symbol:

Abcb5

Name:

ATP binding cassette subfamily B member 5

RGD ID:

1566342

Description:

Predicted to have ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Predicted to be involved in eye development; regulation of membrane potential; and transmembrane transport. Predicted to localize to integral component of plasma membrane. Orthologous to human ABCB5 (ATP binding cassette subfamily B member 5); INTERACTS WITH 2,4,6-tribromophenol (ortholog); aflatoxin B1 (ortholog); calcitriol (ortholog).

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

ATP-binding cassette sub-family B member 5; ATP-binding cassette, sub-family B (MDR/TAP), member 5; ATP-binding cassette, subfamily B (MDR/TAP), member 5; LOC314537; RGD1566342; similar to ATP-binding cassette, sub-family B, member 5

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ABCB5 (ATP binding cassette subfamily B member 5)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Abcb5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5)	HGNC	Treefam, EggNOG, NCBI, OMA, HomoloGene, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Abcb5 (ATP binding cassette subfamily B member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ABCB5 (ATP binding cassette subfamily B member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ABCB5 (ATP binding cassette subfamily B member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Abcb5 (ATP binding cassette subfamily B member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ABCB5 (ATP binding cassette subfamily B member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	ABCB5 (ATP binding cassette subfamily B member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Abcb5 (ATP binding cassette subfamily B member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ABCB5 (ATP binding cassette subfamily B member 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Abcb5 (ATP-binding cassette, sub-family B (MDR/TAP), member 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	abcb4 (ATP-binding cassette, sub-family B (MDR/TAP), member 4)	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	Mdr50	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	STE6	Alliance	DIOPT (InParanoid\|OrthoInspector)
Caenorhabditis elegans (roundworm):	pgp-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-6	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-7	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-8	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG10226	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Mdr49	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Mdr65	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-3	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-4	Alliance	DIOPT (Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-11	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-12	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-13	Alliance	DIOPT (OMA\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	pgp-14	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	139,836,528 - 139,932,830 (-)	NCBI
Rnor_6.0 Ensembl	6	146,805,599 - 146,902,339 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	6	146,805,481 - 146,902,339 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	155,713,932 - 155,809,554 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	146,177,114 - 146,287,478 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	6	137,483,710 - 137,579,013 (-)	NCBI		Celera
Cytogenetic Map	6	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colorectal Neoplasms (ISO)

melanoma (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,4,6-tribromophenol (ISO)

aflatoxin B1 (ISO)

calcitriol (ISO)

cisplatin (ISO)

doxorubicin (ISO)

folic acid (ISO)

hydralazine (ISO)

methotrexate (ISO)

propanal (ISO)

quinolin-8-ol (ISO)

silicon dioxide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

eye development (ISO)

regulation of membrane potential (ISO)

transmembrane transport (IBA,ISO)

Cellular Component

integral component of membrane (IBA)

integral component of plasma membrane (ISO)

Molecular Function

ATP binding (IEA)

ATPase-coupled transmembrane transporter activity (IBA)

efflux transmembrane transporter activity (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	RGD automated data pipeline
3.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12960149	PMID:25030174

Genomics

Comparative Map Data

Abcb5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	139,836,528 - 139,932,830 (-)	NCBI
Rnor_6.0 Ensembl	6	146,805,599 - 146,902,339 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	6	146,805,481 - 146,902,339 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	155,713,932 - 155,809,554 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	146,177,114 - 146,287,478 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
Celera	6	137,483,710 - 137,579,013 (-)	NCBI		Celera
Cytogenetic Map	6	q33	NCBI

ABCB5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	7	20,615,207 - 20,777,038 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	7	20,615,667 - 20,757,008 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	20,655,290 - 20,796,631 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	20,653,741 - 20,761,821 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	7	20,460,284 - 20,568,487	NCBI
Celera	7	20,639,480 - 20,782,083 (+)	NCBI
Cytogenetic Map	7	p21.1	NCBI
HuRef	7	20,544,004 - 20,681,429 (+)	NCBI		HuRef
CHM1_1	7	20,655,593 - 20,797,106 (+)	NCBI		CHM1_1
CRA_TCAGchr7v2	7	20,706,592 - 20,847,927 (+)	NCBI

Abcb5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	118,831,221 - 118,930,169 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	12	118,831,559 - 118,930,156 (-)	Ensembl
GRCm38	12	118,867,486 - 118,966,434 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	118,867,824 - 118,966,421 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	120,106,297 - 120,204,894 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	12	113,093,355 - 113,192,288 (-)	NCBI			mm8
MGSCv36	12	119,311,950 - 119,410,523 (-)	NCBI			mm8
Cytogenetic Map	12	F2	NCBI

Abcb5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	23,283,263 - 23,379,000 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955410	23,283,263 - 23,379,000 (+)	NCBI	ChiLan1.0	ChiLan1.0

ABCB5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	20,617,567 - 20,746,683 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	20,620,875 - 20,746,634 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	21,302,954 - 21,432,569 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

ABCB5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	34,645,722 - 34,760,636 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	34,637,196 - 34,760,433 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	34,141,285 - 34,303,183 (+)	NCBI
ROS_Cfam_1.0	14	34,525,456 - 34,686,254 (+)	NCBI
UMICH_Zoey_3.1	14	34,643,386 - 34,806,295 (+)	NCBI
UNSW_CanFamBas_1.0	14	34,343,924 - 34,506,781 (+)	NCBI
UU_Cfam_GSD_1.0	14	34,654,940 - 34,841,620 (+)	NCBI

Abcb5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	78,898,499 - 79,045,176 (+)	NCBI
SpeTri2.0	NW_004936546	6,573,617 - 6,720,294 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ABCB5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	89,595,284 - 89,738,368 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	89,620,783 - 89,751,876 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	98,854,311 - 99,073,375 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ABCB5
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	37,491,638 - 37,620,002 (-)	NCBI
ChlSab1.1 Ensembl	21	37,492,483 - 37,619,527 (-)	Ensembl

Abcb5
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624739	9,802,817 - 9,976,572 (-)	NCBI

Position Markers

BE107320

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	6	146,792,986 - 146,793,142	NCBI	Rnor6.0
Rnor_5.0	6	155,701,502 - 155,701,658	UniSTS	Rnor5.0
RGSC_v3.4	6	146,177,297 - 146,177,454	UniSTS	RGSC3.4
Celera	6	137,471,213 - 137,471,370	UniSTS
RH 3.4 Map	6	905.7	UniSTS
Cytogenetic Map	6	q33	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	117355600	147991367	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	68781170	147991367	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	104363890	147991367	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	68781170	147991367	Rat
2293085	Iddm29	Insulin dependent diabetes mellitus QTL 29	7.66		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	127286494	147249902	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	127286494	147991367	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	101207574	147991367	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	75
Count of miRNA genes:	64
Interacting mature miRNAs:	72
Transcripts:	ENSRNOT00000050893, ENSRNOT00000074197
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	nervous system	reproductive system
High
Medium
Low		3
Below cutoff	3	8

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_006225905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240713	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000050893 ⟹ ENSRNOP00000045152

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	146,805,599 - 146,902,339 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000074197 ⟹ ENSRNOP00000066405

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	146,826,451 - 146,861,787 (-)	Ensembl

RefSeq Acc Id:

XM_006225905 ⟹ XP_006225967

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Celera	6	137,483,710 - 137,579,013 (-)	NCBI

Sequence:

show sequence

ATGGCACATTCTGAAAGAGCCAACGGGTTGCAAGAAAGTAATCAGAGATATGGATCTCTGCAAG
AACAACTGCCTAAAGCAGGAAATCAAGCTGTCGGACCTATTGAGATATTCCGTTTTGCTGATAA
TCTGGACATTGTCCTCATGACTCTGGGAATACTAGCATCGATGATAAATGGAGCCACTGTTCCT
TTAATGTCCCTGGTTTTAGGAGAAATAAGTGACCATTTTATTAATGGATGCCTAGTCCAAACTA
ACAAAACTAAATATCAGAACTGTTCTCAGTCTCAAGAAAAGTTGAATGAAGATATCATTATGTT
GACTCTCTATTATGTTGGGATAGGAGCAGCTGCCCTCGTTTTGGGCTACGTGCAGATTTCCTTT
TGGGTCATAACCGCAGCCCGGCAAACCACAAGAATCCGAAAACAGTTTTTTCATTCGATTTTGG
CACAAGACATCAGCTGGTTTGATGGCACTGACATCTGTGAACTTAACACCCGCATGAATGGTGA
CATCAGCAAACTCTGTGATGGTATTGGAGATAAGATCCCTCTGATGTTTCAGAATATATCTGGG
TTTTCTATTGGCCTCGTGATAAGCTTGATAAAGAGCTGGAAACTCTCGCTGGCGATTCTGTCCA
CGTCTCCTCTCATAATGGCTGCATCAGCACTGTGCTCTAGGATGGTCATCTCATTGACCAGTAA
GGAGCTGGATGCCTATTCCAAAGCTGGGGCTGTAGCTGAAGAAGCTTTGTCATCAATCCGAACA
GTCACAGCCTTTGGAGCCCAAGAGAAAGAAATTCAAAGGTATACACAGAATCTAAAGGACGCCA
AGGACGCTGGCATAAAGAGGGCTATAGCTTCAAAGCTGTCTCTTGGAGCCGTCTACTTCTTTAT
GAATGGAGCCTACGGACTGGCTTTTTGGTATGGAACCTCCTTGATTTTTGGTGGAGAACCTGGT
TACACCGTCGGGACTATTCTTGCTGTTTTCTTCAGTGTGATCCACAGTAGTTACTGCATCGGGT
CTGTAGCCCCTCACTTGGAAACCTTCACTATAGCCAGAGGAGCCGCTTTTAATATCTTTCATGT
TATTGATAAGAAACCCAATATAGATAACTTTTCAACAGCTGGATATAAACCTGAATCTATAGAA
GGAAACATAGAATTTAAAAACGTTTCTTTCAGCTATCCATCAAGACCTTCTGCCAAGATTCTGA
AAGGCTTCAATCTCAAGATTAAGTCTGGAGAGACAGTAGCTTTGGTTGGTCCCAGTGGCAGTGG
CAAGACTACCACAGTCCAGCTTCTGCAGAGGCTGTATGACCCAGAAGAGGGCTGTATCACGGTA
GATGAGAATGACATCCGAACCCAAAACGTGCGACATTACCGAGAGCAAATTGGAGTGGTCAGCC
AAGAGCCGGTTTTGTTTGGTACCACCATCGGTAACAATATTAAGTTTGGCCGTGAAGGCGTGAG
TGAAGAAGAAATGGAGCAGGCAGCGAGGGAGGCAAACGCCTACGACTTCATAATGGCCTTTCCT
AAGAAATTTAATACACTAGTAGGGGAAAAAGGAGCTCAGATGAGTGGAGGCCAGAAACAGAGAA
TCGCCATTGCTCGAGCGCTAGTTCGAAACCCCAAAATTCTAATCCTAGATGAGGCTACATCTGC
CCTCGACACAGAGAGTGAGTCACTTGTTCAAGCCGCACTGGAGAAGGCAAGCAAAGGCCGGACT
ACACTTGTGGTAGCACACCGGCTCTCCACTATTCGTGGGGCAGACCTGATTGTGACGATGAAGG
ATGGCGAGGTGGTGGAGAAAGGGATCCATGCTGAACTAATGGCAAAGCAGGGACTGTACTACTC
CCTCGCTGTGGCACAGGATATTAAAAAGGTCGATGAACAAATGGAGTCAAGGACATGCTCCGCT
GCAGGGAATGCCAGCAATGGTTCTCTGTGCAATGTGAATAGCGCCAAGTCCCCCTGCACTGACC
AGTTTGAGGAAGCTGTACCCCATCAAAAGACAACTCTTCCTGAAGTTTCACTATTAAAAATATT
TAAATTAAGCAAGTCCGAGTGGCCTTTTGTGGTTCTGGGAACTTTGGCTTCTGCTTTAAATGGG
TCTGTTCACCCAGCATTTTCCATCATCTTTGGAAAATTGGTCACTATGTTCGAAGATAAAAATA
AAACTACATTAAAGCAGGATGCAGAGCTCTACTCTATGATGTTAGTCGTCTTGGGCATAGTGGC
TCTTGTCACCTACTTGATGCAGGGGTTGTTTTATGGCAGAGCAGAAGAAATTTTAGCCATGAGG
TTAAGACACTCAGCATTCAAAGCCATGCTCTATCAGGATATGGCCTGGTATGATGAGAAAGACA
ACAGCACTGGAGCCCTGACCACAACGTTAGCTGTGGACGTAGCACAGATCCGGGGTGCAGCAAC
TTCAAGGCTTGGTATCATAACACAAGATGTGACCAACATGAGTTTGTCCATCCTTATCTCCTTC
GTCTATGGATGGGAGATGACACTCCTGATTCTCAGCTTTGCACCTATACTTGCAGTGACAGGAA
TGATTCAAACTGCAGCAATGGCTGGCTTCGCCAACAAGGATAAGCAAGAGCTTAAGCGTGCCGG
GAAGATAGCAACAGAAGCTGTGGAGAACATACGTACGGTAGTGTCATTAACAAGAGAGAAAGCC
TTTGAGCACATGTATGAGGAGACGCTACGGACCCAACACAGAAATGCCTTGAAGAGAGCACATA
TCACTGGAAGCTGTTATGCGGTCAGCCATGCTTTTGTGCATTTCGCCCACGCAGCAGGTTTCCG
GTTTGGAGCCTATTTGATTCAAGCTGGACGGATGACGCCCGAAGGCATGTTCATAGTCTTTACT
GCCATTGCATATGGGGCTATGGCCATTGGAGAAACGCTTGTTTGGGCTCCTGAATATTCCAAAG
CCAAGGCTGGAGCTGCACATCTGTTTGCTTTGCTGAAAAATAAGCCAAGTATAGACAGCTGCAG
TCAAAATGGAGAAAAACCAGACGCCTGTGAAGGGAACTTAGAATTTCGAGAAGTCTCGTTCTTC
TATCCTTGTCGGCCAGAAGTTCCTGTCCTTCAAGACATGTCCCTCAGCATTGAGAAAGGGAAGA
CAGTAGCATTTGTTGGGAGCAGTGGCTGTGGGAAAAGCACGTGTGTTCAACTGCTACAAAGATT
TTATGACCCCATGAAAGGACAAGTGCTGCTTGACGGCGTCGATGTGAAAGAATTGAACGTGCAA
TGGCTGCGTTCCCAGACAGCCATCGTCTCCCAAGAGCCTGTGCTCTTCAACTGTAGCATTGCTG
AGAACATTGCCTATGGTGATAACAGCCGCATGGTGCCCTTAGAGGAGATCAAAGAGGTCGCAGA
TGCAGCCAACATCCATTCTTTCATTGAAGGGCTCCCCGGGAAATACAGCACCCAAGTGGGACTA
AGAGGCATGCACCTTTCTGGCGGCCAGAAACAAAGACTGGCTATTGCAAGGGCTCTTCTCCGGA
AGCCGAAAATTTTACTGCTGGATGAGGCCACTTCAGCCCTTGACAATGAGAGCGAGAAGATGGT
TCAACAGGCCCTCGACAAAGCCCGGAGAGGGAGGACCTGCCTAGTAGTGGCTCACAGACTCTCC
ACAATACAGAATGCAGATATGATCGTCGTTCTGCAAAATGGAAGAATCAAGGAGCAGGGGACTC
ATCAGGAGCTCCTGAGAAATGGAGAGACTTACTTTAAATTAGCAACCGCGCATTAGTAGTGGCG
CCAGCAGGTGCACTGACGCTGCCGGCCTTGCTTGCACTTGGATCTTGGCGGAATGAAGAGTACA
CAGTCATTTCTTGGCCTGCTCTAGACTCTTACTGCAATGTCAATAC

hide sequence

RefSeq Acc Id:

XM_006240713 ⟹ XP_006240775

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	139,836,528 - 139,932,830 (-)	NCBI
Rnor_6.0	6	146,805,481 - 146,902,339 (-)	NCBI
Rnor_5.0	6	155,713,932 - 155,809,554 (-)	NCBI

Sequence:

show sequence

ATGGCACATTCTGAAAGAGCCAACGGGTTGCAAGAAAGTAATCAGAGATATGGATCTCTGCAAG
AACAACTGCCTAAAGCAGGAAATCAAGCTGTCGGACCTATTGAGATATTCCGTTTTGCTGATAA
TCTGGACATTGTCCTCATGACTCTGGGAATACTAGCATCGATGATAAATGGAGCCACTGTTCCT
TTAATGTCCCTGGTTTTAGGAGAAATAAGTGACCATTTTATTAATGGATGCCTAGTCCAAACTA
ACAAAACTAAATATCAGAACTGTTCTCAGTCTCAAGAAAAGTTGAATGAAGATATCATTATGTT
GACTCTCTATTATGTTGGGATAGGAGCAGCTGCCCTCGTTTTGGGCTACGTGCAGATTTCCTTT
TGGGTCATAACCGCAGCCCGGCAAACCACAAGAATCCGAAAACAGTTTTTTCATTCGATTTTGG
CACAAGACATCAGCTGGTTTGATGGCACTGACATCTGTGAACTTAACACCCGCATGAATGGTGA
CATCAGCAAACTCTGTGATGGTATTGGAGATAAGATCCCTCTGATGTTTCAGAATATATCTGGG
TTTTCTATTGGCCTCGTGATAAGCTTGATAAAGAGCTGGAAACTCTCGCTGGCGATTCTGTCCA
CGTCTCCTCTCATAATGGCTGCATCAGCACTGTGCTCTAGGATGGTCATCTCATTGACCAGTAA
GGAGCTGGATGCCTATTCCAAAGCTGGGGCTGTAGCTGAAGAAGCTTTGTCATCAATCCGAACA
GTCACAGCCTTTGGAGCCCAAGAGAAAGAAATTCAAAGGTATACACAGAATCTAAAGGACGCCA
AGGACGCTGGCATAAAGAGGGCTATAGCTTCAAAGCTGTCTCTTGGAGCCGTCTACTTCTTTAT
GAATGGAGCCTACGGACTGGCTTTTTGGTATGGAACCTCCTTGATTTTTGGTGGAGAACCTGGT
TACACCGTCGGGACTATTCTTGCTGTTTTCTTCAGTGTGATCCACAGTAGTTACTGCATCGGGT
CTGTAGCCCCTCACTTGGAAACCTTCACTATAGCCAGAGGAGCCGCTTTTAATATCTTTCATGT
TATTGATAAGAAACCCAATATAGATAACTTTTCAACAGCTGGATATAAACCTGAATCTATAGAA
GGAAACATAGAATTTAAAAACGTTTCTTTCAGCTATCCATCAAGACCTTCTGCCAAGATTCTGA
AAGGCTTCAATCTCAAGATTAAGTCTGGAGAGACAGTAGCTTTGGTTGGTCCCAGTGGCAGTGG
CAAGACTACCACAGTCCAGCTTCTGCAGAGGCTGTATGACCCAGAAGAGGGCTGTATCACGGTA
GATGAGAATGACATCCGAACCCAAAACGTGCGACATTACCGAGAGCAAATTGGAGTGGTCAGCC
AAGAGCCGGTTTTGTTTGGTACCACCATCGGTAACAATATTAAGTTTGGCCGTGAAGGCGTGAG
TGAAGAAGAAATGGAGCAGGCAGCGAGGGAGGCAAACGCCTACGACTTCATAATGGCCTTTCCT
AAGAAATTTAATACACTAGTAGGGGAAAAAGGAGCTCAGATGAGTGGAGGCCAGAAACAGAGAA
TCGCCATTGCTCGAGCGCTAGTTCGAAACCCCAAAATTCTAATCCTAGATGAGGCTACATCTGC
CCTCGACACAGAGAGTGAGTCACTTGTTCAAGCCGCACTGGAGAAGGCAAGCAAAGGCCGGACT
ACACTTGTGGTAGCACACCGGCTCTCCACTATTCGTGGGGCAGACCTGATTGTGACGATGAAGG
ATGGCGAGGTGGTGGAGAAAGGGATCCATGCTGAACTAATGGCAAAGCAGGGACTGTACTACTC
CCTCGCTGTGGCACAGGATATTAAAAAGGTCGATGAACAAATGGAGTCAAGGACATGCTCCGCT
GCAGGGAATGCCAGCAATGGTTCTCTGTGCAATGTGAATAGCGCCAAGTCCCCCTGCACTGACC
AGTTTGAGGAAGCTGTACCCCATCAAAAGACAACTCTTCCTGAAGTTTCACTATTAAAAATATT
TAAATTAAGCAAGTCCGAGTGGCCTTTTGTGGTTCTGGGAACTTTGGCTTCTGCTTTAAATGGG
TCTGTTCACCCAGCATTTTCCATCATCTTTGGAAAATTGGTCACTATGTTCGAAGATAAAAATA
AAACTACATTAAAGCAGGATGCAGAGCTCTACTCTATGATGTTAGTCGTCTTGGGCATAGTGGC
TCTTGTCACCTACTTGATGCAGGGGTTGTTTTATGGCAGAGCAGAAGAAATTTTAGCCATGAGG
TTAAGACACTCAGCATTCAAAGCCATGCTCTATCAGGATATGGCCTGGTATGATGAGAAAGACA
ACAGCACTGGAGCCCTGACCACAACGTTAGCTGTGGACGTAGCACAGATCCGGGGTGCAGCAAC
TTCAAGGCTTGGTATCATAACACAAGATGTGACCAACATGAGTTTGTCCATCCTTATCTCCTTC
GTCTATGGATGGGAGATGACACTCCTGATTCTCAGCTTTGCACCTATACTTGCAGTGACAGGAA
TGATTCAAACTGCAGCAATGGCTGGCTTCGCCAACAAGGATAAGCAAGAGCTTAAGCGTGCCGG
GAAGATAGCAACAGAAGCTGTGGAGAACATACGTACGGTAGTGTCATTAACAAGAGAGAAAGCC
TTTGAGCACATGTATGAGGAGACGCTACGGACCCAACACAGAAATGCCTTGAAGAGAGCACATA
TCACTGGAAGCTGTTATGCGGTCAGCCATGCTTTTGTGCATTTCGCCCACGCAGCAGGTTTCCG
GTTTGGAGCCTATTTGATTCAAGCTGGACGGATGACGCCCGAAGGCATGTTCATAGTCTTTACT
GCCATTGCATATGGGGCTATGGCCATTGGAGAAACGCTTGTTTGGGCTCCTGAATATTCCAAAG
CCAAGGCTGGAGCTGCACATCTGTTTGCTTTGCTGAAAAATAAGCCAAGTATAGACAGCTGCAG
TCAAAATGGAGAAAAACCAGACGCCTGTGAAGGGAACTTAGAATTTCGAGAAGTCTCGTTCTTC
TATCCTTGTCGGCCAGAAGTTCCTGTCCTTCAAGACATGTCCCTCAGCATTGAGAAAGGGAAGA
CAGTAGCATTTGTTGGGAGCAGTGGCTGTGGGAAAAGCACGTGTGTTCAACTGCTACAAAGATT
TTATGACCCCATGAAAGGACAAGTGCTGCTTGACGGCGTCGATGTGAAAGAATTGAACGTGCAA
TGGCTGCGTTCCCAGACAGCCATCGTCTCCCAAGAGCCTGTGCTCTTCAACTGTAGCATTGCTG
AGAACATTGCCTATGGTGATAACAGCCGCATGGTGCCCTTAGAGGAGATCAAAGAGGTCGCAGA
TGCAGCCAACATCCATTCTTTCATTGAAGGGCTCCCCGGGAAATACAGCACCCAAGTGGGACTA
AGAGGCATGCACCTTTCTGGCGGCCAGAAACAAAGACTGGCTATTGCAAGGGCTCTTCTCCGGA
AGCCGAAAATTTTACTGCTGGATGAGGCCACTTCAGCCCTTGACAATGAGAGCGAGAAGATGGT
TCAACAGGCCCTCGACAAAGCCCGGAGAGGGAGGACCTGCCTAGTAGTGGCTCACAGACTCTCC
ACAATACAGAATGCAGATATGATCGTCGTTCTGCAAAATGGAAGAATCAAGGAGCAGGGGACTC
ATCAGGAGCTCCTGAGAAATGGAGAGACTTACTTTAAATTAGCAACCGCGCATTAGTAGTGGCG
CCAGCAGGTGCACTGACGCTGCCGGCCTTGCTTGCACTTGGATCTTGGCGGAATGAAGAGTACA
CAGTCATTTCTTGGCCTGCTCTAGACTCTTACTGCAATGTCAATAC

hide sequence

Protein Sequences


Protein RefSeqs	XP_006240775	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL89093	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_006225967 ⟸ XM_006225905

- Sequence:

show sequence

MAHSERANGLQESNQRYGSLQEQLPKAGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVP
LMSLVLGEISDHFINGCLVQTNKTKYQNCSQSQEKLNEDIIMLTLYYVGIGAAALVLGYVQISF
WVITAARQTTRIRKQFFHSILAQDISWFDGTDICELNTRMNGDISKLCDGIGDKIPLMFQNISG
FSIGLVISLIKSWKLSLAILSTSPLIMAASALCSRMVISLTSKELDAYSKAGAVAEEALSSIRT
VTAFGAQEKEIQRYTQNLKDAKDAGIKRAIASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPG
YTVGTILAVFFSVIHSSYCIGSVAPHLETFTIARGAAFNIFHVIDKKPNIDNFSTAGYKPESIE
GNIEFKNVSFSYPSRPSAKILKGFNLKIKSGETVALVGPSGSGKTTTVQLLQRLYDPEEGCITV
DENDIRTQNVRHYREQIGVVSQEPVLFGTTIGNNIKFGREGVSEEEMEQAAREANAYDFIMAFP
KKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQAALEKASKGRT
TLVVAHRLSTIRGADLIVTMKDGEVVEKGIHAELMAKQGLYYSLAVAQDIKKVDEQMESRTCSA
AGNASNGSLCNVNSAKSPCTDQFEEAVPHQKTTLPEVSLLKIFKLSKSEWPFVVLGTLASALNG
SVHPAFSIIFGKLVTMFEDKNKTTLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEEILAMR
LRHSAFKAMLYQDMAWYDEKDNSTGALTTTLAVDVAQIRGAATSRLGIITQDVTNMSLSILISF
VYGWEMTLLILSFAPILAVTGMIQTAAMAGFANKDKQELKRAGKIATEAVENIRTVVSLTREKA
FEHMYEETLRTQHRNALKRAHITGSCYAVSHAFVHFAHAAGFRFGAYLIQAGRMTPEGMFIVFT
AIAYGAMAIGETLVWAPEYSKAKAGAAHLFALLKNKPSIDSCSQNGEKPDACEGNLEFREVSFF
YPCRPEVPVLQDMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQVLLDGVDVKELNVQ
WLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPGKYSTQVGL
RGMHLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKMVQQALDKARRGRTCLVVAHRLS
TIQNADMIVVLQNGRIKEQGTHQELLRNGETYFKLATAH

hide sequence

RefSeq Acc Id:

XP_006240775 ⟸ XM_006240713

- UniProtKB:

D4AEL4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAHSERANGLQESNQRYGSLQEQLPKAGNQAVGPIEIFRFADNLDIVLMTLGILASMINGATVP
LMSLVLGEISDHFINGCLVQTNKTKYQNCSQSQEKLNEDIIMLTLYYVGIGAAALVLGYVQISF
WVITAARQTTRIRKQFFHSILAQDISWFDGTDICELNTRMNGDISKLCDGIGDKIPLMFQNISG
FSIGLVISLIKSWKLSLAILSTSPLIMAASALCSRMVISLTSKELDAYSKAGAVAEEALSSIRT
VTAFGAQEKEIQRYTQNLKDAKDAGIKRAIASKLSLGAVYFFMNGAYGLAFWYGTSLIFGGEPG
YTVGTILAVFFSVIHSSYCIGSVAPHLETFTIARGAAFNIFHVIDKKPNIDNFSTAGYKPESIE
GNIEFKNVSFSYPSRPSAKILKGFNLKIKSGETVALVGPSGSGKTTTVQLLQRLYDPEEGCITV
DENDIRTQNVRHYREQIGVVSQEPVLFGTTIGNNIKFGREGVSEEEMEQAAREANAYDFIMAFP
KKFNTLVGEKGAQMSGGQKQRIAIARALVRNPKILILDEATSALDTESESLVQAALEKASKGRT
TLVVAHRLSTIRGADLIVTMKDGEVVEKGIHAELMAKQGLYYSLAVAQDIKKVDEQMESRTCSA
AGNASNGSLCNVNSAKSPCTDQFEEAVPHQKTTLPEVSLLKIFKLSKSEWPFVVLGTLASALNG
SVHPAFSIIFGKLVTMFEDKNKTTLKQDAELYSMMLVVLGIVALVTYLMQGLFYGRAEEILAMR
LRHSAFKAMLYQDMAWYDEKDNSTGALTTTLAVDVAQIRGAATSRLGIITQDVTNMSLSILISF
VYGWEMTLLILSFAPILAVTGMIQTAAMAGFANKDKQELKRAGKIATEAVENIRTVVSLTREKA
FEHMYEETLRTQHRNALKRAHITGSCYAVSHAFVHFAHAAGFRFGAYLIQAGRMTPEGMFIVFT
AIAYGAMAIGETLVWAPEYSKAKAGAAHLFALLKNKPSIDSCSQNGEKPDACEGNLEFREVSFF
YPCRPEVPVLQDMSLSIEKGKTVAFVGSSGCGKSTCVQLLQRFYDPMKGQVLLDGVDVKELNVQ
WLRSQTAIVSQEPVLFNCSIAENIAYGDNSRMVPLEEIKEVADAANIHSFIEGLPGKYSTQVGL
RGMHLSGGQKQRLAIARALLRKPKILLLDEATSALDNESEKMVQQALDKARRGRTCLVVAHRLS
TIQNADMIVVLQNGRIKEQGTHQELLRNGETYFKLATAH

hide sequence

RefSeq Acc Id:

ENSRNOP00000045152 ⟸ ENSRNOT00000050893

RefSeq Acc Id:

ENSRNOP00000066405 ⟸ ENSRNOT00000074197

Protein Domains

ABC transmembrane type-1 ABC transporter

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1566342	AgrOrtholog
Ensembl Genes	ENSRNOG00000006398	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000045152	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000066405	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000050893	UniProtKB/TrEMBL
	ENSRNOT00000074197	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1560.10	UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/TrEMBL
	ABC1_TM_sf	UniProtKB/TrEMBL
	ABC_transporter-like	UniProtKB/TrEMBL
	ABC_transporter_CS	UniProtKB/TrEMBL
	ABC_transptrTM_dom_typ1	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Type_I_exporter	UniProtKB/TrEMBL
KEGG Report	rno:314537	UniProtKB/TrEMBL
NCBI Gene	314537	ENTREZGENE
PANTHER	PTHR24221	UniProtKB/TrEMBL
Pfam	ABC_membrane	UniProtKB/TrEMBL
	ABC_tran	UniProtKB/TrEMBL
PhenoGen	Abcb5	PhenoGen
PROSITE	ABC_TM1F	UniProtKB/TrEMBL
	ABC_TRANSPORTER_1	UniProtKB/TrEMBL
	ABC_TRANSPORTER_2	UniProtKB/TrEMBL
SMART	AAA	UniProtKB/TrEMBL
Superfamily-SCOP	ABC_TM_1	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	D4AEL4	ENTREZGENE, UniProtKB/TrEMBL
	M0RA64_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-09	Abcb5	ATP binding cassette subfamily B member 5	Abcb5	ATP-binding cassette, subfamily B (MDR/TAP), member 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-11-16	Abcb5	ATP-binding cassette, subfamily B (MDR/TAP), member 5	Abcb5	ATP-binding cassette, sub-family B (MDR/TAP), member 5	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Abcb5	ATP-binding cassette, sub-family B (MDR/TAP), member 5	RGD1566342_predicted	similar to ATP-binding cassette, sub-family B, member 5 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1566342_predicted	similar to ATP-binding cassette, sub-family B, member 5 (predicted)	LOC314537	similar to ATP-binding cassette, sub-family B, member 5	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC314537	similar to ATP-binding cassette, sub-family B, member 5			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD