Symbol:
SCNN1D
Name:
sodium channel epithelial 1 subunit delta
RGD ID:
1346343
HGNC Page
HGNC:10601
Description:
Contributes to sodium channel activity. Involved in cellular response to acidic pH; intracellular sodium ion homeostasis; and sodium ion import across plasma membrane. Located in actin cytoskeleton and membrane. Part of sodium channel complex. Is active in apical plasma membrane.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
amiloride-sensitive sodium channel subunit delta; delta-ENaC; delta-NaCH; dNaCh; ENaCd; ENaCdelta; epithelial Na(+) channel subunit delta; epithelial sodium channel subunit delta; MGC149710; MGC149711; nonvoltage-gated sodium channel 1 subunit delta; SCNED; sodium channel epithelial 1 delta subunit; sodium channel, non voltage gated 1 delta subunit; sodium channel, non-voltage-gated 1, delta subunit; sodium channel, nonvoltage-gated 1, delta; sodium channel, voltage-gated, type I, delta polypeptide
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Chinchilla lanigera (long-tailed chinchilla):
Scnn1d (sodium channel epithelial 1 subunit delta) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
SCNN1D (sodium channel epithelial 1 subunit delta) NCBI
Ortholog
Canis lupus familiaris (dog):
SCNN1D (sodium channel epithelial 1 subunit delta) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Scnn1d (sodium channel epithelial 1 subunit delta) NCBI
Ortholog
Sus scrofa (pig):
SCNN1D (sodium channel epithelial 1 subunit delta) HGNC
Ensembl, NCBI, OrthoDB, Panther
Chlorocebus sabaeus (green monkey):
SCNN1D (sodium channel epithelial 1 subunit delta) NCBI
Ortholog
Heterocephalus glaber (naked mole-rat):
Scnn1d (sodium channel epithelial 1 subunit delta) NCBI
Ortholog
Alliance orthologs 3
Caenorhabditis elegans (roundworm):
del-1
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
unc-105
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
asic-1
Alliance
DIOPT (InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
mec-10
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
unc-8
Alliance
DIOPT (InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
deg-1
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
mec-4
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PhylomeDB|SonicParanoid)
Xenopus laevis (African clawed frog):
scnn1d.L
Alliance
DIOPT (Xenbase)
Xenopus tropicalis (tropical clawed frog):
scnn1d
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoFinder|PANTHER|PhylomeDB)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 1,280,436 - 1,292,025 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 1,280,436 - 1,292,029 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 1,215,816 - 1,227,405 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 1,207,439 - 1,217,272 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 1,257,498 - 1,267,332 NCBI Celera 1 1,353,752 - 1,364,767 (-) NCBI Celera Cytogenetic Map 1 p36.33 NCBI HuRef 1 487,469 - 498,615 (+) NCBI HuRef CHM1_1 1 1,202,865 - 1,213,108 (+) NCBI CHM1_1 T2T-CHM13v2.0 1 709,443 - 723,551 (+) NCBI T2T-CHM13v2.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - SMPDB
SCNN1D Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 1 1,280,436 - 1,292,025 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 1 1,280,436 - 1,292,029 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 1 1,215,816 - 1,227,405 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 1 1,207,439 - 1,217,272 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 1 1,257,498 - 1,267,332 NCBI Celera 1 1,353,752 - 1,364,767 (-) NCBI Celera Cytogenetic Map 1 p36.33 NCBI HuRef 1 487,469 - 498,615 (+) NCBI HuRef CHM1_1 1 1,202,865 - 1,213,108 (+) NCBI CHM1_1 T2T-CHM13v2.0 1 709,443 - 723,551 (+) NCBI T2T-CHM13v2.0
Scnn1d Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 NW_004955486 9,508,435 - 9,514,107 (-) NCBI ChiLan1.0 ChiLan1.0
SCNN1D Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 1 226,935,345 - 226,952,596 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 1 225,632,019 - 225,649,369 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 1 35,437 - 46,538 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 1 1,239,074 - 1,248,062 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 1 1,238,512 - 1,247,649 (+) Ensembl panpan1.1 panPan2
SCNN1D Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 5 56,455,677 - 56,466,035 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 5 56,461,939 - 56,465,595 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 5 56,532,576 - 56,542,936 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 5 56,658,510 - 56,668,872 (+) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 5 56,649,231 - 56,659,591 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 5 56,541,513 - 56,551,874 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 5 56,931,514 - 56,941,874 (+) NCBI UU_Cfam_GSD_1.0
Scnn1d
SCNN1D
SCNN1D
Scnn1d
.
Predicted Target Of
Count of predictions: 2999 Count of miRNA genes: 834 Interacting mature miRNAs: 1019 Transcripts: ENST00000325425, ENST00000338555, ENST00000379099, ENST00000379101, ENST00000379116, ENST00000400928, ENST00000467651, ENST00000470022 Prediction methods: Miranda, Rnahybrid Result types: miRGate_prediction
1298451 OSTEAR17_H Osteoarthritis QTL 17 (human) 2.4 0.0004 Joint/bone inflammation osteoarthritis 11 1 25188105 Human 407115031 GWAS764007_H platelet count QTL GWAS764007 (human) 0.000003 platelet quantity (VT:0003179) platelet count (CMO:0000029) 1 1290932 1290933 Human 1298463 BP9_H Blood pressure QTL 9 (human) 3.9 Blood pressure hypertension susceptibility 1 1 25188105 Human
SHGC-74130
Human Assembly Chr Position (strand) Source JBrowse GRCh37 1 1,226,808 - 1,226,987 UniSTS GRCh37 Build 36 1 1,216,671 - 1,216,850 RGD NCBI36 Celera 1 1,354,174 - 1,354,353 RGD Cytogenetic Map 1 p36.3-p36.2 UniSTS HuRef 1 498,014 - 498,193 UniSTS TNG Radiation Hybrid Map 1 76246.0 UniSTS GeneMap99-GB4 RH Map 1 15.89 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
entire extraembryonic component
1204
2432
2788
2242
4942
1723
2343
4
622
1929
464
2268
7265
6438
52
3708
847
1731
1610
170
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENST00000325425 ⟹ ENSP00000321594
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 1 1,282,109 - 1,292,024 (+) Ensembl
Ensembl Acc Id:
ENST00000338555 ⟹ ENSP00000339504
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 1 1,280,588 - 1,292,024 (+) Ensembl
Ensembl Acc Id:
ENST00000379099 ⟹ ENSP00000368393
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 1 1,287,109 - 1,290,943 (+) Ensembl
Ensembl Acc Id:
ENST00000379101 ⟹ ENSP00000449804
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 1 1,280,472 - 1,291,373 (+) Ensembl
Ensembl Acc Id:
ENST00000379116 ⟹ ENSP00000368411
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 1 1,280,436 - 1,292,025 (+) Ensembl
Ensembl Acc Id:
ENST00000400928 ⟹ ENSP00000383717
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 1 1,281,224 - 1,292,029 (+) Ensembl
Ensembl Acc Id:
ENST00000467651
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 1 1,282,164 - 1,285,597 (+) Ensembl
Ensembl Acc Id:
ENST00000470022 ⟹ ENSP00000420548
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 1 1,281,925 - 1,286,168 (+) Ensembl
RefSeq Acc Id:
NM_001130413 ⟹ NP_001123885
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38 1 1,280,436 - 1,292,025 (+) NCBI GRCh37 1 1,215,816 - 1,227,409 (+) ENTREZGENE HuRef 1 487,469 - 498,615 (+) ENTREZGENE CHM1_1 1 1,202,865 - 1,213,108 (+) NCBI T2T-CHM13v2.0 1 709,443 - 723,551 (+) NCBI
Sequence:
CCTGGGCGACAGCGAGACTCCATCTCAATAAATAAAAAAAAAAAAGAGTTGTTATCAGTAGAAGGGAATGTCTGGTTACAGTATGGCGTTGTGCAGATGAAGGTCTTATCGCAGATGAAGCCACCAGG
hide sequence
RefSeq Acc Id:
NR_037668
RefSeq Status:
VALIDATED
Type:
NON-CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38 1 1,280,436 - 1,292,025 (+) NCBI GRCh37 1 1,215,816 - 1,227,409 (+) ENTREZGENE HuRef 1 487,469 - 498,615 (+) ENTREZGENE CHM1_1 1 1,202,865 - 1,213,108 (+) NCBI T2T-CHM13v2.0 1 709,443 - 723,551 (+) NCBI
Sequence:
CCTGGGCGACAGCGAGACTCCATCTCAATAAATAAAAAAAAAAAAGAGTTGTTATCAGTAGAAGGGAATGTCTGGTTACAGTATGGCGTTGTGCAGATGAAGGTCTTATCGCAGATGAAGCCACCAGG
hide sequence
RefSeq Acc Id:
NP_001123885 ⟸ NM_001130413
- UniProtKB:
Q5T7L3 (UniProtKB/Swiss-Prot), Q09HT0 (UniProtKB/Swiss-Prot), Q08AQ3 (UniProtKB/Swiss-Prot), B3KSD7 (UniProtKB/Swiss-Prot), B1PS44 (UniProtKB/Swiss-Prot), A9Z1X6 (UniProtKB/Swiss-Prot), Q8NA24 (UniProtKB/Swiss-Prot), P51172 (UniProtKB/Swiss-Prot), A6NNF7 (UniProtKB/TrEMBL)
- Sequence:
MRAVLSQKTTPLPRYLWPGHLSGPRRLTWSWCSDHRTPTCRELGSPHPTPCTGPARGWPRRGGGPCGFTSAGHVLCGYPLCLLSGPIQGCGTGLGDSSMAFLSRTSPVAAASFQSRQEARGSILLQSC
hide sequence
Ensembl Acc Id:
ENSP00000383717 ⟸ ENST00000400928
Ensembl Acc Id:
ENSP00000339504 ⟸ ENST00000338555
Ensembl Acc Id:
ENSP00000321594 ⟸ ENST00000325425
Ensembl Acc Id:
ENSP00000368393 ⟸ ENST00000379099
Ensembl Acc Id:
ENSP00000449804 ⟸ ENST00000379101
Ensembl Acc Id:
ENSP00000368411 ⟸ ENST00000379116
Ensembl Acc Id:
ENSP00000420548 ⟸ ENST00000470022
RGD ID: 6786802 Promoter ID: HG_KWN:147 Type: Non-CpG SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: HeLa_S3 Transcripts: ENST00000338555, ENST00000379101, NM_001130413, NM_002978, OTTHUMT00000005803, UC001ADT.1, UC001ADU.1, UC001ADX.2 Position: Human Assembly Chr Position (strand) Source Build 36 1 1,206,911 - 1,207,411 (+) MPROMDB
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2019-12-03
SCNN1D
sodium channel epithelial 1 subunit delta
SCNN1D
sodium channel epithelial 1 delta subunit
Symbol and/or name change
5135510 APPROVED
2016-02-10
SCNN1D
sodium channel epithelial 1 delta subunit
sodium channel, non voltage gated 1 delta subunit
Symbol and/or name change
5135510 APPROVED
2015-01-20
SCNN1D
sodium channel, non voltage gated 1 delta subunit
sodium channel, non-voltage-gated 1, delta subunit
Symbol and/or name change
5135510 APPROVED
2012-03-01
SCNN1D
sodium channel, non-voltage-gated 1, delta subunit
SCNN1D
sodium channel, nonvoltage-gated 1, delta
Symbol and/or name change
5135510 APPROVED
