Or2g25 (olfactory receptor family 2 subfamily G member 25) - Rat Genome Database

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Gene: Or2g25 (olfactory receptor family 2 subfamily G member 25) Rattus norvegicus
Analyze
Symbol: Or2g25
Name: olfactory receptor family 2 subfamily G member 25
RGD ID: 1333714
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be active in plasma membrane; INTERACTS WITH benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC100910859; olfactory receptor 1702; olfactory receptor 2G3-like; olfactory receptor gene Olr1702; olfactory receptor Olr1702; Olr1702
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820816,136 - 817,089 (+)NCBIGRCr8
mRatBN7.220810,880 - 811,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20807,707 - 815,510 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx20817,806 - 818,759 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.020821,252 - 822,205 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020744,661 - 745,614 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,110,773 - 1,111,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,110,773 - 1,111,726 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0201,108,083 - 1,109,036 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.420769,684 - 770,637 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.120769,683 - 770,637 (+)NCBI
Celera201,578,396 - 1,579,349 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or2g25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820816,136 - 817,089 (+)NCBIGRCr8
mRatBN7.220810,880 - 811,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20807,707 - 815,510 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx20817,806 - 818,759 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.020821,252 - 822,205 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020744,661 - 745,614 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,110,773 - 1,111,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,110,773 - 1,111,726 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0201,108,083 - 1,109,036 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.420769,684 - 770,637 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.120769,683 - 770,637 (+)NCBI
Celera201,578,396 - 1,579,349 (+)NCBICelera
Cytogenetic Map20p12NCBI
OR2G3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381247,605,586 - 247,606,515 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1247,605,586 - 247,606,515 (+)EnsemblGRCh38hg38GRCh38
GRCh371247,768,888 - 247,769,817 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361245,835,511 - 245,836,440 (+)NCBINCBI36Build 36hg18NCBI36
Build 341244,094,928 - 244,095,858NCBI
Celera1221,067,685 - 221,068,614 (+)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1218,163,051 - 218,163,980 (+)NCBIHuRef
CHM1_11249,041,244 - 249,042,173 (+)NCBICHM1_1
T2T-CHM13v2.01247,042,412 - 247,043,341 (+)NCBIT2T-CHM13v2.0

Variants

.
Variants in Or2g25
11 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:89
Count of miRNA genes:78
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000041697
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

reproductive system
High
Medium
Low 1
Below cutoff 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000041697   ⟹   ENSRNOP00000042999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,110,773 - 1,111,726 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105603   ⟹   ENSRNOP00000088799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20807,707 - 815,510 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107174   ⟹   ENSRNOP00000089679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20807,707 - 815,510 (+)Ensembl
RefSeq Acc Id: NM_001001374   ⟹   NP_001001374
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr820816,136 - 817,089 (+)NCBI
mRatBN7.220810,880 - 811,833 (+)NCBI
Rnor_6.0201,110,773 - 1,111,726 (+)NCBI
Rnor_5.0201,108,083 - 1,109,036 (+)NCBI
RGSC_v3.420769,684 - 770,637 (+)RGD
Celera201,578,396 - 1,579,349 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001001374 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000088799
  ENSRNOP00000088799.1
  ENSRNOP00000089679.1
Reference Protein Sequences
RefSeq Acc Id: NP_001001374   ⟸   NM_001001374
- UniProtKB: A0A8I6A7T2 (UniProtKB/TrEMBL),   A6KR39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000042999   ⟸   ENSRNOT00000041697
RefSeq Acc Id: ENSRNOP00000088799   ⟸   ENSRNOT00000105603
RefSeq Acc Id: ENSRNOP00000089679   ⟸   ENSRNOT00000107174
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZS89-F1-model_v2 AlphaFold D3ZS89 1-317 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333714 AgrOrtholog
BioCyc Gene G2FUF-5054 BioCyc
Ensembl Genes ENSRNOG00000050738 Ensembl
  ENSRNOG00000065757 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000105603 ENTREZGENE
  ENSRNOT00000105603.1 UniProtKB/TrEMBL
  ENSRNOT00000107174.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:294157 UniProtKB/TrEMBL
NCBI Gene 294157 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2g25 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050738 RatGTEx
  ENSRNOG00000065757 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6A7T2 ENTREZGENE, UniProtKB/TrEMBL
  A6KR39 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or2g25  olfactory receptor family 2 subfamily G member 25  Olr1702  olfactory receptor 1702  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr1702  olfactory receptor 1702  LOC100910859  olfactory receptor 2G3-like  Data merged from RGD:6496339 737654 PROVISIONAL
2012-07-05 LOC100910859  olfactory receptor 2G3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1702  olfactory receptor 1702   Olr1702_predicted  olfactory receptor 1702 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1702_predicted  olfactory receptor 1702 (predicted)      Symbol and Name status set to approved 70820 APPROVED