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Gene: Adamdec1 (ADAM-like, decysin 1) Mus musculus

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Symbol:

Adamdec1

Name:

ADAM-like, decysin 1

RGD ID:

1320431

MGI Page

MGI

Description:

Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Is expressed in foregut-midgut junction; hindgut; large intestine; midgut; and stomach. Orthologous to human ADAMDEC1 (ADAM like decysin 1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

2210414L24Rik; a disintegrin and metalloproteinase domain-like protein decysin 1; a disintegrin and metalloproteinase domain-like protein decysin-1; ADAM DEC1; ADAM-like protein decysin 1; ADAM-like protein decysin-1; AI574231; Dc; Dcsn; decysin; disintegrin metalloprotease (decysin)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADAMDEC1 (ADAM like decysin 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Adamdec1 (ADAM-like, decysin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Adamdec1 (ADAM like decysin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADAMDEC1 (ADAM like decysin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ADAMDEC1 (ADAM like decysin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Adamdec1 (ADAM like decysin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ADAMDEC1 (ADAM like decysin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ADAMDEC1 (ADAM like decysin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Adamdec1 (ADAM like decysin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Adamdec1 (ADAM-like, decysin 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ADAMDEC1 (ADAM like decysin 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	adam28 (ADAM metallopeptidase domain 28)	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	tag-275	Alliance	DIOPT (InParanoid\|PANTHER)
Caenorhabditis elegans (roundworm):	F27D9.7	Alliance	DIOPT (InParanoid\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	adam28.2	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	adam28.1	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	68,800,829 - 68,819,535 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	68,800,829 - 68,819,544 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	68,563,387 - 68,582,072 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	68,563,380 - 68,582,095 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	69,181,444 - 69,200,129 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	67,516,717 - 67,535,402 (-)	NCBI		MGSCv36	mm8
Celera	14	66,331,214 - 66,349,962 (-)	NCBI		Celera
Cytogenetic Map	14	D1	NCBI
cM Map	14	35.69	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adamdec1	Mouse	1,2-dimethylhydrazine	multiple interactions	EXP		6480464	[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:22206623
Adamdec1	Mouse	17beta-estradiol	decreases expression	EXP		6480464	Estradiol results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:39298647
Adamdec1	Mouse	17beta-estradiol	decreases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	Estradiol results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:35192832
Adamdec1	Mouse	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	EXP		6480464	AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of ADAMDEC1 mRNA]	CTD	PMID:16891777
Adamdec1	Mouse	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of ADAMDEC1 mRNA	CTD	PMID:16891777 more ...
Adamdec1	Mouse	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of ADAMDEC1 mRNA	CTD	PMID:21570461 and PMID:26377647
Adamdec1	Mouse	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	Tetrachlorodibenzodioxin affects the expression of ADAMDEC1 mRNA	CTD	PMID:22298810
Adamdec1	Mouse	2,4-dibromophenyl 2,4,5-tribromophenyl ether	affects expression	EXP		6480464	2 more ...	CTD	PMID:38648751
Adamdec1	Mouse	4,4'-diaminodiphenylmethane	increases expression	EXP		6480464	4 and 4'-diaminodiphenylmethane results in increased expression of ADAMDEC1 mRNA	CTD	PMID:18648102
Adamdec1	Mouse	4,4'-sulfonyldiphenol	decreases expression	EXP		6480464	bisphenol S results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:39298647
Adamdec1	Mouse	4-hydroxyphenyl retinamide	increases expression	EXP		6480464	Fenretinide results in increased expression of ADAMDEC1 mRNA	CTD	PMID:28973697
Adamdec1	Mouse	5-aza-2'-deoxycytidine	increases expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	Decitabine results in increased expression of ADAMDEC1 mRNA	CTD	PMID:21856257
Adamdec1	Mouse	6-propyl-2-thiouracil	decreases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	Propylthiouracil results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:24780913
Adamdec1	Mouse	all-trans-retinoic acid	increases expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	Tretinoin results in increased expression of ADAMDEC1 mRNA	CTD	PMID:33167477
Adamdec1	Mouse	antirheumatic drug	decreases expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	Antirheumatic Agents results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:24449571
Adamdec1	Mouse	arsenous acid	increases expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	Arsenic Trioxide results in increased expression of ADAMDEC1 mRNA	CTD	PMID:20458559
Adamdec1	Mouse	benzo[a]pyrene	increases expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased expression of ADAMDEC1 mRNA	CTD	PMID:20064835
Adamdec1	Mouse	benzo[a]pyrene	decreases methylation	ISO	ADAMDEC1 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of ADAMDEC1 5' UTR and Benzo(a)pyrene results in decreased methylation of ADAMDEC1 promoter	CTD	PMID:27901495
Adamdec1	Mouse	benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of ADAMDEC1 mRNA	CTD	PMID:21964900 and PMID:32417428
Adamdec1	Mouse	benzo[b]fluoranthene	increases expression	EXP		6480464	benzo(b)fluoranthene results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26377693
Adamdec1	Mouse	Benzo[k]fluoranthene	increases expression	EXP		6480464	benzo(k)fluoranthene results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26377693
Adamdec1	Mouse	beta-naphthoflavone	increases expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	beta-Naphthoflavone results in increased expression of ADAMDEC1 mRNA	CTD	PMID:32858204
Adamdec1	Mouse	bisphenol A	increases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	bisphenol A results in increased expression of ADAMDEC1 mRNA	CTD	PMID:27178563 and PMID:35192832
Adamdec1	Mouse	bisphenol A	decreases methylation	ISO	ADAMDEC1 (Homo sapiens)	6480464	bisphenol A results in decreased methylation of ADAMDEC1 gene	CTD	PMID:31601247
Adamdec1	Mouse	bisphenol A	decreases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	bisphenol A results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:25181051
Adamdec1	Mouse	bisphenol A	multiple interactions	ISO	Adamdec1 (Rattus norvegicus)	6480464	[bisphenol A co-treated with Testosterone] results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26496021
Adamdec1	Mouse	carbon nanotube	decreases expression	EXP		6480464	Nanotubes more ...	CTD	PMID:25554681 and PMID:25620056
Adamdec1	Mouse	chrysene	increases expression	EXP		6480464	chrysene results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26377693
Adamdec1	Mouse	copper atom	multiple interactions	ISO	Adamdec1 (Rattus norvegicus)	6480464	[Copper co-treated with Dietary Sucrose] results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26033743
Adamdec1	Mouse	copper atom	increases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	Copper deficiency results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26033743
Adamdec1	Mouse	copper(0)	multiple interactions	ISO	Adamdec1 (Rattus norvegicus)	6480464	[Copper co-treated with Dietary Sucrose] results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26033743
Adamdec1	Mouse	copper(0)	increases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	Copper deficiency results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26033743
Adamdec1	Mouse	diarsenic trioxide	increases expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	Arsenic Trioxide results in increased expression of ADAMDEC1 mRNA	CTD	PMID:20458559
Adamdec1	Mouse	dibenz[a,h]anthracene	increases expression	EXP		6480464	1 more ...	CTD	PMID:26377693
Adamdec1	Mouse	dibenzofurans	increases expression	EXP		6480464	Dibenzofurans results in increased expression of ADAMDEC1 mRNA	CTD	PMID:34254344
Adamdec1	Mouse	diclofenac	increases expression	EXP		6480464	Diclofenac results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26934552
Adamdec1	Mouse	epoxiconazole	increases expression	EXP		6480464	epoxiconazole results in increased expression of ADAMDEC1 mRNA	CTD	PMID:35436446
Adamdec1	Mouse	folic acid	multiple interactions	EXP		6480464	[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:22206623
Adamdec1	Mouse	formaldehyde	increases expression	ISO	ADAMDEC1 (Homo sapiens)	6480464	Formaldehyde results in increased expression of ADAMDEC1 mRNA	CTD	PMID:23649840
Adamdec1	Mouse	genistein	decreases expression	EXP		6480464	Genistein results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:32186404
Adamdec1	Mouse	inulin	multiple interactions	EXP		6480464	[perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ADAMDEC1 mRNA	CTD	PMID:36331819
Adamdec1	Mouse	N-nitrosodiethylamine	multiple interactions	EXP		6480464	[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:24535843
Adamdec1	Mouse	N-nitrosodiethylamine	decreases expression	EXP		6480464	Diethylnitrosamine results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:24535843
Adamdec1	Mouse	perfluorooctane-1-sulfonic acid	multiple interactions	EXP		6480464	[perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ADAMDEC1 mRNA	CTD	PMID:36331819
Adamdec1	Mouse	phenobarbital	multiple interactions	EXP		6480464	[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ADAMDEC1 mRNA and NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ADAMDEC1 mRNA]	CTD	PMID:19482888 and PMID:24535843
Adamdec1	Mouse	phenobarbital	affects expression	EXP		6480464	Phenobarbital affects the expression of ADAMDEC1 mRNA	CTD	PMID:23091169
Adamdec1	Mouse	phenobarbital	decreases expression	EXP		6480464	Phenobarbital results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:19482888
Adamdec1	Mouse	pravastatin	increases expression	EXP		6480464	Pravastatin results in increased expression of ADAMDEC1 mRNA	CTD	PMID:27225895
Adamdec1	Mouse	pravastatin	increases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	Pravastatin results in increased expression of ADAMDEC1 mRNA	CTD	PMID:27225895
Adamdec1	Mouse	silicon dioxide	decreases expression	EXP		6480464	Silicon Dioxide results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:23221170
Adamdec1	Mouse	testosterone	multiple interactions	ISO	Adamdec1 (Rattus norvegicus)	6480464	[bisphenol A co-treated with Testosterone] results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26496021
Adamdec1	Mouse	tetraphene	increases expression	EXP		6480464	benz(a)anthracene results in increased expression of ADAMDEC1 mRNA	CTD	PMID:26377693
Adamdec1	Mouse	thioacetamide	increases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	Thioacetamide results in increased expression of ADAMDEC1 mRNA	CTD	PMID:23411599
Adamdec1	Mouse	titanium dioxide	decreases expression	EXP		6480464	titanium dioxide results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:23557971
Adamdec1	Mouse	Tributyltin oxide	increases expression	EXP		6480464	bis(tri-n-butyltin)oxide results in increased expression of ADAMDEC1 mRNA	CTD	PMID:18958704
Adamdec1	Mouse	trichloroethene	decreases methylation	ISO	Adamdec1 (Rattus norvegicus)	6480464	Trichloroethylene results in decreased methylation of ADAMDEC1 gene	CTD	PMID:27618143
Adamdec1	Mouse	valproic acid	decreases methylation	ISO	ADAMDEC1 (Homo sapiens)	6480464	Valproic Acid results in decreased methylation of ADAMDEC1 gene	CTD	PMID:29154799
Adamdec1	Mouse	zaragozic acid A	affects expression	EXP		6480464	squalestatin 1 affects the expression of ADAMDEC1 mRNA	CTD	PMID:27225895
Adamdec1	Mouse	zaragozic acid A	decreases expression	ISO	Adamdec1 (Rattus norvegicus)	6480464	squalestatin 1 results in decreased expression of ADAMDEC1 mRNA	CTD	PMID:27225895

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adamdec1	Mouse	proteolysis	involved_in	IBA	PANTHER:PTN000224844 more ...	2290270		GO_Central	GO_REF:0000033
Adamdec1	Mouse	proteolysis	involved_in	IEA	UniProtKB-KW:KW-0645	2290270		UniProt	GO_REF:0000043

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adamdec1	Mouse	cellular_component	is_active_in	ND		2290270		MGI	GO_REF:0000015
Adamdec1	Mouse	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	2290270		UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adamdec1	Mouse	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	2290270		UniProt	GO_REF:0000043
Adamdec1	Mouse	metalloendopeptidase activity	enables	IEA	InterPro:IPR001590	2290270		InterPro	GO_REF:0000002
Adamdec1	Mouse	metalloendopeptidase activity	enables	IBA	PANTHER:PTN000224844 more ...	2290270		GO_Central	GO_REF:0000033

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Adamdec1	Mouse	decreased circulating interleukin-10 level		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	decreased colon length		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	increased circulating interleukin-1 beta level		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	increased circulating interleukin-6 level		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	increased neutrophil cell number		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	increased susceptibility to bacterial infection		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	increased susceptibility to bacterial infection induced morbidity/mortality		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	increased susceptibility to colitis induced morbidity/mortality		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	increased susceptibility to induced colitis		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	increased susceptibility to weight loss		IAGP		5509061		MGI	PMID:27226416
Adamdec1	Mouse	intestinal inflammation		IAGP		5509061		MGI	PMID:27226416

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:10349636	PMID:11042159	PMID:11076861	PMID:11673514	PMID:12037602	PMID:12477932	PMID:12606478	PMID:15489334	PMID:16141072	PMID:16141073	PMID:17268172	PMID:18477666
PMID:21267068	PMID:21677750	PMID:21873635	PMID:23892084	PMID:27226416	PMID:27480124	PMID:35085231	PMID:35563399	PMID:35830795	PMID:38063920	PMID:38355799

Adamdec1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	68,800,829 - 68,819,535 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	68,800,829 - 68,819,544 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	68,563,387 - 68,582,072 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	68,563,380 - 68,582,095 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	69,181,444 - 69,200,129 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	67,516,717 - 67,535,402 (-)	NCBI		MGSCv36	mm8
Celera	14	66,331,214 - 66,349,962 (-)	NCBI		Celera
Cytogenetic Map	14	D1	NCBI
cM Map	14	35.69	NCBI

ADAMDEC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	24,384,285 - 24,406,013 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	24,384,285 - 24,406,013 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	24,241,798 - 24,263,526 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	24,297,916 - 24,319,471 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	24,297,915 - 24,319,471	NCBI
Celera	8	23,205,384 - 23,227,107 (+)	NCBI		Celera
Cytogenetic Map	8	p21.2	NCBI
HuRef	8	22,786,429 - 22,808,152 (+)	NCBI		HuRef
CHM1_1	8	24,443,956 - 24,465,678 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	24,659,416 - 24,681,139 (+)	NCBI		T2T-CHM13v2.0

Adamdec1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	47,076,011 - 47,097,065 (-)	NCBI		GRCr8
mRatBN7.2	15	42,900,629 - 42,921,684 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	42,900,636 - 42,921,712 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	44,765,281 - 44,786,328 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	45,915,508 - 45,936,555 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	44,360,879 - 44,381,942 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	49,485,604 - 49,521,638 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	49,485,611 - 49,505,553 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	53,218,715 - 53,238,690 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	48,250,970 - 48,272,395 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	48,267,607 - 48,288,140 (-)	NCBI
Celera	15	42,534,343 - 42,555,121 (-)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

Adamdec1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955403	47,421,102 - 47,439,501 (+)	NCBI	ChiLan1.0	ChiLan1.0

ADAMDEC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	42,892,991 - 42,914,657 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	18,627,118 - 18,648,797 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	23,653,257 - 23,674,893 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	20,570,606 - 20,590,177 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	20,570,606 - 20,591,383 (+)	Ensembl	panpan1.1		panPan2

ADAMDEC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	33,046,404 - 33,061,512 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	33,046,312 - 33,061,731 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	33,630,692 - 33,646,155 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	33,252,217 - 33,267,658 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	33,252,441 - 33,267,811 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	33,200,387 - 33,215,843 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	33,056,965 - 33,072,405 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	33,215,149 - 33,230,607 (-)	NCBI		UU_Cfam_GSD_1.0

Adamdec1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	10,873,411 - 10,883,718 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	7,686,841 - 7,697,078 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936555	7,686,841 - 7,697,084 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADAMDEC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	8,456,134 - 8,471,088 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	8,455,964 - 8,483,308 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	9,498,092 - 9,512,852 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADAMDEC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	22,516,511 - 22,537,706 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	22,516,639 - 22,537,731 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	19,647,053 - 19,668,264 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adamdec1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	19,519,526 - 19,534,259 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	19,519,526 - 19,534,409 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Adamdec1
508 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	323
Count of miRNA genes:	254
Interacting mature miRNAs:	277
Transcripts:	ENSMUST00000022641
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357589	Kdnw2_m	kidney weight 2 (mouse)			Not determined		14	20887473	121269804	Mouse
1301777	Bglq15_m	body growth late QTL 15 (mouse)			Not determined		14	42962416	76962593	Mouse
1301489	Lbm10_m	lean body mass 10 (mouse)			Not determined		14	53761296	87761529	Mouse
1357527	Epfpq1_m	epididymal fat percentage QTL 1 (mouse)			Not determined		14	21062450	71885801	Mouse
1301424	Skull21_m	skull morphology 21 (mouse)			Not determined		14	42962416	76962593	Mouse
4142364	Pbwg18_m	postnatal body weight growth 18 (mouse)			Not determined		14	52281984	86282125	Mouse
4141400	Nilac8_m	nicotine induced locomotor activity 8 (mouse)			Not determined		14	43065847	77066045	Mouse
10043889	Cia52_m	collagen induced arthritis QTL 52 (mouse)			Not determined		14	56082381	90082509	Mouse
27226774	Tibl15_m	tibia length 15, 10 week (mouse)					14	30321957	87937436	Mouse
1301562	Hwq1_m	heart weight quantitative locus 1 (mouse)			Not determined		14	56546745	90546941	Mouse
1357565	wrmod1_m	wobbler modifier 1 (mouse)			Not determined		14	58179640	101859473	Mouse
1300666	Fembm2_m	femoral bone morphometry 2 (mouse)			Not determined		14	62397460	96397680	Mouse
4142419	Tgq26_m	triglyceride QTL 26 (mouse)			Not determined			40337319	74337319	Mouse
1300605	El5_m	epilepsy 5 (mouse)			Not determined		14	49455425	83455556	Mouse
11039527	Ccc2_m	colitis susceptibility in the Collaborative Cross 2 (mouse)					14	59918612	94138217	Mouse
1301091	Bbaa21_m	B.burgdorferi-associated arthritis 21 (mouse)			Not determined		14	43065847	77066045	Mouse
12880432	Fgf23lq3_m	FGF23 serum level QTL 3 (mouse)					14	53937440	87937440	Mouse
10043887	Cia50_m	collagen induced arthritis QTL 50 (mouse)			Not determined		14	37430185	71430320	Mouse
1300805	Mors3_m	modifier of obesity related sterility 3 (mouse)			Not determined		14	43037270	77037418	Mouse

AI574231

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	14	68,563,563 - 68,563,695	UniSTS	GRCm38
MGSCv37	14	69,181,620 - 69,181,752	UniSTS	GRCm37
Celera	14	66,331,390 - 66,331,522	UniSTS
Cytogenetic Map	14	D2	UniSTS
Whitehead/MRC_RH	14	778.43	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	NM_021475	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC154706	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ242912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK008929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK156586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC026542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC046324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CT025563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000022641 ⟹ ENSMUSP00000022641

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	14	68,800,829 - 68,819,544 (-)	Ensembl
GRCm38.p6 Ensembl	14	68,563,380 - 68,582,095 (-)	Ensembl

RefSeq Acc Id:

NM_021475 ⟹ NP_067450

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	14	68,800,829 - 68,819,535 (-)	NCBI
GRCm38	14	68,563,387 - 68,582,072 (-)	ENTREZGENE
MGSCv37	14	69,181,444 - 69,200,129 (-)	RGD
Celera	14	66,331,214 - 66,349,962 (-)	RGD
cM Map	14		ENTREZGENE

Sequence:

show sequence

CTGGCCACTGGAGAGACCATAGCTGTATGCTGCCTGGGACTTCTCGGCTACCCACAGAAGCCAGCATGTCTTGGGTCCTGCTTTCAGTCCTGTGGCTTATCATTCAAATCCAAGTGATAGATGCAACG
TTAACCCCCGAGTTAAAGCCTCACGAAATAGTTCGTCCTAAAAAACTACCCATTTCACAGAAAAGAGGGCTTGAGAACAACCAGACAGAGAGATATGGCAAAGAGGAAAAATATGCACCAGAAGTTCA
ATATCAGATCATACTAAATGGAGAAGAAATTGTTTTTCACCTAAAGAGAACCAAGCATCTTCTGGGGCCAGACTACACTGAAACATCTTACTCACCCAGAGGAGAAGAGAGCACCAGACACTCTCAGG
ATGTGAAACCCTGCTACTATGAAGGCCACATCCAAAATGCAAGGGGCTCTCTGGCCAGGATCAGTACCTGTGATGGGTTGAGAGGGTACTTCACACATCGTGATCAGAGATATCAAATAAAGCCTCTA
CAAAGCACAGATGAGGGAGAGCATGCTGTTCTCCCATACAGCTGGAAGGGACAAGACACAGTTCATGACAAGGATGCTGAGAAGCAAGTTGTCAGGAAACGAAGCCATCTTCGAACTTCCAGGTCACT
CAAAAACCCAAATGAAGACTTACTTCAAGGACAGAAGTACATTGGTCTCTTTTTGGTGCTGGATAATGCCTATTATAAGCTGTATAATGGGAATGTGACTCAGATGAGAACCTTTCTGTTCAAGGTGC
TGAATCTGCTCAATATGATTTATAAAACCATAAATATTCAAGTGTCTTTGGTGGGCATGGAGATCTGGTCTGACCAGGACAAGATAAAGGTGGAGCCCAACCTTGGTGCCACGTTCACACACTTCATG
AGATGGCATTATTCTAACCTGGGGAAAAGGATCCATAACCACGCCCAGCTTCTCAGTGGAGCTAGCTTCCGCCATGGACGTGTGGGAATGGCAGCTGGGAATTCCTTTTGTACTACATCGTCTGTGTC
TGTAATTGAGGCTAAAAAAAAGAATAATGTGGCTCTTGTTGCACTGATGTCACATGAGTTGGGCCACGCCCTTGGTATGAAGGATGTTCCATATTATACCAAGTGTCCCTCTGGCAGCTGTGTGATGA
ATCAGTACCTGAGTTCAAAATTCCCCAAGGATTTCAGTACCGTCAGCCGTTCTCATTTTCAAGGGTTTCTCTCATCTAGAAATGCAAGGTGTCTGCTGCTGGCACCTGACCCTAAAAACATAATAAAA
CCAACATGTGGGAACCAAGTCCTGGATGTGGGAGAAGAGTGTGACTGTGGCTCTCCTGAGGAATGTACCAATCTTTGCTGTGAGCCCCTGACATGTAGGCTGAAATCTCAACCTGACTGCAGTGAAGC
ATCCAACCACATCACAGAATGATCCAGTGTCTAATTCACAGAGAAGCTACTTTGCCAGGACAGAAGTCCAGACCCTGCCTCTGCCAGGAAGCCCGCCTATCCTGTGCACCTATACAGACAAACCTATC
TCTGTGTGCCATGTTCTCTGTGAACCCATGACTTCAATCACTGAAGAAGAAGAATGCCCCAAAATACGACTTGTACCTGTCATGAATATGTAGGCATTTTCTCCTCAGTACTCCATAAATAATAGAGT
ATAACAGCTATTTGTATAGCGTTTTTGTAGATTAAGTTTTAGAAGTAGTCTAGAGATGACAAGATACTTAGAAGAATTTTAGTAGTTGTATGCAAACATACTCCAGGTCTAGAAAGACTGTTAGTCCT
GAGATTTGGGAATCTGTGTAATCATGGAGCCGAATCCTGGTGAACAATGAAGGAAGATCTTTGCTTTTCTCTTTCCTTTCTACTTTATGTGTTTCTACCAGTCCAGTCAACAGGTCAATAGACATGCT
AAGGTGATGCTGTCTGTTCATTCAGGTCTTATCTATAGTGTGAGTGTGAGGAGCCTGAAAGTGTGGTTTTAGTTTCACTTTTTGGAGGACAAAATAGATGAACCTTTGCAGAACTTCTCAACGTACTC
CACAGAATTGTTGAGTTAATCCCAAACTGCAAAGTGACTAGTAATTTAACCCTAAATCTCTTTGTTCCTGAGGCGTAGGAATCAAAGCCTGCCACCTGCTGAGGGAGGGAGCTGGCAGAAAGAACAGA
GCCCCAGCCCCTTCCTGTCTCTGGGCAGCCAGTTTGTCTTACATCCTGTAAACTTCCCGGATTTTCTGGCTCGTGGGAATATTGGTTACATTCAAACACTTTTCATTTGAGCAAATAGAGTTTCTCAC
ACCATCATGTATAAGAATTATTTTTGAGAAGTCTGTGTGGCTTATTTCTTAGTGGAAATGGAAAAGTAAGGCTTCATTCATTGGTTTTTGTAATAAACTATGCTATCA

hide sequence


Protein RefSeqs	NP_067450	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH46324	(Get FASTA)	NCBI Sequence Viewer
	BAE33767	(Get FASTA)	NCBI Sequence Viewer
	CAB54557	(Get FASTA)	NCBI Sequence Viewer
	EDL35959	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000022641
	ENSMUSP00000022641.8
GenBank Protein	Q9R0X2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_067450 ⟸ NM_021475
- Peptide Label:	precursor
- UniProtKB:	Q9R0X2 (UniProtKB/Swiss-Prot), Q3U0T4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLPGTSRLPTEASMSWVLLSVLWLIIQIQVIDATLTPELKPHEIVRPKKLPISQKRGLENNQTERYGKEEKYAPEVQYQIILNGEEIVFHLKRTKHLLGPDYTETSYSPRGEESTRHSQDVKPCYYEG HIQNARGSLARISTCDGLRGYFTHRDQRYQIKPLQSTDEGEHAVLPYSWKGQDTVHDKDAEKQVVRKRSHLRTSRSLKNPNEDLLQGQKYIGLFLVLDNAYYKLYNGNVTQMRTFLFKVLNLLNMIYK TINIQVSLVGMEIWSDQDKIKVEPNLGATFTHFMRWHYSNLGKRIHNHAQLLSGASFRHGRVGMAAGNSFCTTSSVSVIEAKKKNNVALVALMSHELGHALGMKDVPYYTKCPSGSCVMNQYLSSKFP KDFSTVSRSHFQGFLSSRNARCLLLAPDPKNIIKPTCGNQVLDVGEECDCGSPEECTNLCCEPLTCRLKSQPDCSEASNHITE hide sequence

Ensembl Acc Id:

ENSMUSP00000022641 ⟸ ENSMUST00000022641

Protein Domains

Disintegrin Peptidase M12B

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9R0X2-F1-model_v2	AlphaFold	Q9R0X2	1-467	view protein structure

RGD ID:

8682836

Promoter ID:

EPDNEW_M19449

Type:

initiation region

Name:

Adamdec1_1

Description:

Mus musculus ADAM-like, decysin 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	14	68,582,086 - 68,582,146	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000022057	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000022641	ENTREZGENE
	ENSMUST00000022641.9	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.390.10	UniProtKB/Swiss-Prot
	4.10.70.10	UniProtKB/Swiss-Prot
InterPro	Disintegrin_dom	UniProtKB/Swiss-Prot
	Disintegrin_dom_sf	UniProtKB/Swiss-Prot
	MetalloPept_cat_dom_sf	UniProtKB/Swiss-Prot
	Peptidase_M12B	UniProtKB/Swiss-Prot
	Peptidase_M12B_N	UniProtKB/Swiss-Prot
	Reprolysin_adamalysin	UniProtKB/Swiss-Prot
KEGG Report	mmu:58860	UniProtKB/Swiss-Prot
MGD	MGI:1917650	ENTREZGENE
NCBI Gene	Adamdec1	ENTREZGENE
PANTHER	ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN	UniProtKB/Swiss-Prot
	PTHR11905:SF125	UniProtKB/Swiss-Prot
Pfam	Pep_M12B_propep	UniProtKB/Swiss-Prot
	Reprolysin	UniProtKB/Swiss-Prot
PhenoGen	Adamdec1	PhenoGen
PROSITE	ADAM_MEPRO	UniProtKB/Swiss-Prot
	DISINTEGRIN_2	UniProtKB/Swiss-Prot
	ZINC_PROTEASE	UniProtKB/Swiss-Prot
SMART	DISIN	UniProtKB/Swiss-Prot
Superfamily-SCOP	Metalloproteases ('zincins'), catalytic domain	UniProtKB/Swiss-Prot
UniProt	ADEC1_MOUSE	UniProtKB/Swiss-Prot
	Q3U0T4	ENTREZGENE, UniProtKB/TrEMBL
	Q9R0X2	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-08-26	Adamdec1	ADAM-like, decysin 1	2210414L24Rik	RIKEN cDNA 2210414L24 gene	Symbol and/or name updated	27372883	PROVISIONAL
2024-08-21	2210414L24Rik	RIKEN cDNA 2210414L24 gene	Adamdec1	ADAM-like, decysin 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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