Fam83e (family with sequence similarity 83, member E) - Rat Genome Database

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Gene: Fam83e (family with sequence similarity 83, member E) Mus musculus
Analyze
Symbol: Fam83e
Name: family with sequence similarity 83, member E
RGD ID: 1319598
MGI Page MGI
Description: Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. Orthologous to human FAM83E (family with sequence similarity 83 member E).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4930403C10Rik; hypothetical protein LOC73813
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,370,595 - 45,379,179 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,370,636 - 45,378,916 (+)EnsemblGRCm39 Ensembl
GRCm38745,721,171 - 45,729,755 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,721,212 - 45,729,492 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,976,590 - 52,984,862 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,589,262 - 45,592,901 (+)NCBIMGSCv36mm8
Celera741,183,761 - 41,192,041 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21873635   PMID:26073538  


Genomics

Comparative Map Data
Fam83e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,370,595 - 45,379,179 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,370,636 - 45,378,916 (+)EnsemblGRCm39 Ensembl
GRCm38745,721,171 - 45,729,755 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,721,212 - 45,729,492 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,976,590 - 52,984,862 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,589,262 - 45,592,901 (+)NCBIMGSCv36mm8
Celera741,183,761 - 41,192,041 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.46NCBI
FAM83E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,599,961 - 48,615,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,599,961 - 48,615,076 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,103,218 - 49,118,333 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,795,669 - 53,808,506 (-)NCBINCBI36Build 36hg18NCBI36
Celera1945,968,730 - 45,981,559 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,482,899 - 45,495,884 (-)NCBIHuRef
CHM1_11949,105,776 - 49,118,569 (-)NCBICHM1_1
T2T-CHM13v2.01951,594,097 - 51,609,712 (-)NCBIT2T-CHM13v2.0
Fam83e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,328,297 - 105,337,641 (+)NCBIGRCr8
mRatBN7.2196,191,581 - 96,201,182 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,191,742 - 96,201,192 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01101,703,627 - 101,712,238 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,704,746 - 101,711,379 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,782,714 - 102,790,993 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,190,389 - 96,197,390 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,268,499 - 96,275,501 (+)NCBI
Celera190,444,727 - 90,453,338 (+)NCBICelera
Cytogenetic Map1q22NCBI
Fam83e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,933,911 - 1,942,286 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,933,345 - 1,942,707 (+)NCBIChiLan1.0ChiLan1.0
FAM83E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,704,774 - 54,719,197 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,632,393 - 56,645,584 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,602,210 - 45,615,518 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,200,841 - 54,207,709 (-)NCBIpanpan1.1PanPan1.1panPan2
FAM83E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,694,963 - 107,705,303 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,696,416 - 107,705,310 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,216,404 - 107,226,730 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,218,985 - 108,229,306 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,220,587 - 108,229,313 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,885,505 - 107,895,827 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,532,795 - 107,543,122 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,368,510 - 108,378,834 (+)NCBIUU_Cfam_GSD_1.0
Fam83e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,037,527 - 21,046,430 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,656,043 - 2,663,372 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,656,043 - 2,663,372 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM83E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,963,859 - 53,974,010 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,963,543 - 53,974,207 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,711,173 - 49,721,340 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FAM83E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1641,853,953 - 41,874,212 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl641,854,253 - 41,872,125 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607321,719,949 - 21,734,768 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam83e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,259,058 - 5,267,239 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,257,934 - 5,267,760 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:824
Count of miRNA genes:531
Interacting mature miRNAs:618
Transcripts:ENSMUST00000129507, ENSMUST00000146391, ENSMUST00000156689
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse

Markers in Region
AV043694  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38745,725,277 - 45,725,397UniSTSGRCm38
MGSCv37752,980,647 - 52,980,767UniSTSGRCm37
Celera741,187,833 - 41,187,953UniSTS
Cytogenetic Map7B4UniSTS
Whitehead/MRC_RH7570.89UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000129507   ⟹   ENSMUSP00000114397
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,370,636 - 45,378,916 (+)Ensembl
GRCm38.p6 Ensembl745,721,212 - 45,729,492 (+)Ensembl
Ensembl Acc Id: ENSMUST00000210434
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,370,644 - 45,374,283 (+)Ensembl
GRCm38.p6 Ensembl745,721,220 - 45,724,859 (+)Ensembl
Ensembl Acc Id: ENSMUST00000211124
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,375,283 - 45,378,913 (+)Ensembl
GRCm38.p6 Ensembl745,725,859 - 45,729,489 (+)Ensembl
RefSeq Acc Id: NM_001033170   ⟹   NP_001028342
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,370,644 - 45,378,916 (+)NCBI
GRCm38745,721,220 - 45,729,492 (+)NCBI
MGSCv37752,976,590 - 52,984,862 (+)RGD
Celera741,183,761 - 41,192,041 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006541224   ⟹   XP_006541287
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,370,595 - 45,376,132 (+)NCBI
GRCm38745,721,171 - 45,726,708 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003946572
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,370,595 - 45,379,179 (+)NCBI
GRCm38745,721,171 - 45,729,755 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001028342 (Get FASTA)   NCBI Sequence Viewer  
  XP_006541287 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH42793 (Get FASTA)   NCBI Sequence Viewer  
  AAI39285 (Get FASTA)   NCBI Sequence Viewer  
  BAE25923 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000114397
  ENSMUSP00000114397.3
GenBank Protein Q80XS7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001028342   ⟸   NM_001033170
- UniProtKB: B9EIA0 (UniProtKB/Swiss-Prot),   Q3UN25 (UniProtKB/Swiss-Prot),   Q80XS7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006541287   ⟸   XM_006541224
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000114397   ⟸   ENSMUST00000129507

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80XS7-F1-model_v2 AlphaFold Q80XS7 1-481 view protein structure

Promoters
RGD ID:8664079
Promoter ID:EPDNEW_M10071
Type:initiation region
Name:Fam83e_1
Description:Mus musculus family with sequence similarity 83, member E , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38745,721,242 - 45,721,302EPDNEW
RGD ID:6841092
Promoter ID:MM_KWN:50455
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000067022,   OTTMUST00000084935
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36752,976,126 - 52,977,852 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921063 AgrOrtholog
Ensembl Genes ENSMUSG00000054161 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000129507 ENTREZGENE
  ENSMUST00000129507.5 UniProtKB/Swiss-Prot
Gene3D-CATH Endonuclease Chain A UniProtKB/Swiss-Prot
InterPro FAM83 UniProtKB/Swiss-Prot
  FAM83_N UniProtKB/Swiss-Prot
KEGG Report mmu:73813 UniProtKB/Swiss-Prot
MGD MGI:1921063 ENTREZGENE
NCBI Gene 73813 ENTREZGENE
PANTHER PROTEIN FAM83B-RELATED UniProtKB/Swiss-Prot
  UNCHARACTERIZED UniProtKB/Swiss-Prot
Pfam FAM83 UniProtKB/Swiss-Prot
PhenoGen Fam83e PhenoGen
Superfamily-SCOP Phospholipase D/nuclease UniProtKB/Swiss-Prot
UniProt B9EIA0 ENTREZGENE
  FA83E_MOUSE UniProtKB/Swiss-Prot
  Q3UN25 ENTREZGENE
  Q80XS7 ENTREZGENE
UniProt Secondary B9EIA0 UniProtKB/Swiss-Prot
  Q3UN25 UniProtKB/Swiss-Prot