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Gene: Spred2 (sprouty-related EVH1 domain containing 2) Mus musculus

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Symbol:

Spred2

Name:

sprouty-related EVH1 domain containing 2

RGD ID:

1319581

MGI Page

MGI

Description:

Enables protein kinase binding activity; protein serine/threonine kinase inhibitor activity; and stem cell factor receptor binding activity. Involved in negative regulation of cell differentiation and regulation of signal transduction. Acts upstream of or within negative regulation of MAPK cascade. Located in cytoplasmic vesicle and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; heart; and sensory organ. Used to study achondroplasia. Human ortholog(s) of this gene implicated in Noonan syndrome. Orthologous to human SPRED2 (sprouty related EVH1 domain containing 2).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

C79158; Spre; sprouty protein with EVH-1 domain 2, related sequence; sprouty-related, EVH1 domain containing 2; sprouty-related, EVH1 domain-containing protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Related Pseudogenes:

Gm14612

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	19,874,442 - 19,974,026 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	19,874,375 - 19,974,026 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	19,924,442 - 20,024,026 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	19,924,375 - 20,024,026 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	19,824,445 - 19,922,600 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	19,824,445 - 19,922,600 (+)	NCBI		MGSCv36	mm8
Celera	11	22,066,219 - 22,164,240 (+)	NCBI		Celera
Cytogenetic Map	11	A3.1	NCBI
cM Map	11	12.79	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	Noonan syndrome		ISO	RGD:1319580	8554872	ClinVar Annotator: match by term: Noonan syndrome	ClinVar	PMID:25741868\|PMID:34626534
Spred2	Mouse	Noonan Syndrome 14		ISO	RGD:1319580	8554872	ClinVar Annotator: match by term: Noonan syndrome 14	ClinVar	PMID:25741868\|PMID:34626534

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	Alzheimer's disease		ISO	RGD:1319580	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:33589840
Spred2	Mouse	rheumatoid arthritis		ISO	RGD:1319580	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:20453842\|PMID:23143596

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	achondroplasia		IAGP		13592920	OMIM:100800	MouseDO

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	Noonan Syndrome 14		ISO	RGD:1319580	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	(-)-epigallocatechin 3-gallate	multiple interactions	ISO	RGD:1319580	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SPRED2 mRNA	CTD	PMID:22079256
Spred2	Mouse	1,2-dimethylhydrazine	decreases expression	EXP		6480464	1,2-Dimethylhydrazine results in decreased expression of SPRED2 mRNA	CTD	PMID:22206623
Spred2	Mouse	17beta-estradiol	decreases expression	ISO	RGD:1309304	6480464	Estradiol results in decreased expression of SPRED2 mRNA	CTD	PMID:20068009\|PMID:32145629
Spred2	Mouse	17beta-estradiol	decreases expression	ISO	RGD:1319580	6480464	Estradiol results in decreased expression of SPRED2 mRNA	CTD	PMID:19167446
Spred2	Mouse	17beta-estradiol	increases expression	ISO	RGD:1319580	6480464	Estradiol results in increased expression of SPRED2 mRNA	CTD	PMID:23019147\|PMID:31614463
Spred2	Mouse	2,2',4,4'-Tetrabromodiphenyl ether	multiple interactions	ISO	RGD:1319580	6480464	[2,2',4,4'-tetrabromodiphenyl ether affects the methylation of SPRED2 gene] which affects the expression of SPRED2 mRNA	CTD	PMID:32653021
Spred2	Mouse	2,3',4,4',5-Pentachlorobiphenyl	increases expression	EXP		6480464	2,3',4,4',5-pentachlorobiphenyl results in increased expression of SPRED2 mRNA	CTD	PMID:31388691
Spred2	Mouse	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of SPRED2 mRNA	CTD	PMID:21570461
Spred2	Mouse	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:1309304	6480464	Tetrachlorodibenzodioxin results in decreased expression of SPRED2 mRNA	CTD	PMID:33387578
Spred2	Mouse	2,3,7,8-Tetrachlorodibenzofuran	decreases expression	ISO	RGD:1309304	6480464	2,3,7,8-tetrachlorodibenzofuran results in decreased expression of SPRED2 mRNA	CTD	PMID:32109520
Spred2	Mouse	2-hydroxypropanoic acid	increases expression	ISO	RGD:1319580	6480464	Lactic Acid results in increased expression of SPRED2 mRNA	CTD	PMID:30851411
Spred2	Mouse	2-methylcholine	affects expression	ISO	RGD:1319580	6480464	beta-methylcholine affects the expression of SPRED2 mRNA	CTD	PMID:21179406
Spred2	Mouse	2-palmitoylglycerol	increases expression	ISO	RGD:1319580	6480464	2-palmitoylglycerol results in increased expression of SPRED2 mRNA	CTD	PMID:37199045
Spred2	Mouse	3-methylcholanthrene	increases expression	EXP		6480464	Methylcholanthrene results in increased expression of SPRED2 mRNA	CTD	PMID:20713471
Spred2	Mouse	4,4'-sulfonyldiphenol	decreases expression	EXP		6480464	bisphenol S results in decreased expression of SPRED2 mRNA	CTD	PMID:39298647
Spred2	Mouse	acetamide	decreases expression	ISO	RGD:1309304	6480464	acetamide results in decreased expression of SPRED2 mRNA	CTD	PMID:31881176
Spred2	Mouse	aflatoxin B1	affects expression	ISO	RGD:1319580	6480464	Aflatoxin B1 affects the expression of SPRED2 protein	CTD	PMID:20106945
Spred2	Mouse	aflatoxin B1	decreases methylation	ISO	RGD:1319580	6480464	Aflatoxin B1 results in decreased methylation of SPRED2 gene	CTD	PMID:27153756
Spred2	Mouse	all-trans-retinoic acid	increases expression	ISO	RGD:1309304	6480464	Tretinoin results in increased expression of SPRED2 mRNA	CTD	PMID:20488242
Spred2	Mouse	atrazine	decreases expression	ISO	RGD:1319580	6480464	Atrazine results in decreased expression of SPRED2 mRNA	CTD	PMID:22378314
Spred2	Mouse	atrazine	affects methylation	ISO	RGD:1309304	6480464	Atrazine affects the methylation of SPRED2 gene	CTD	PMID:35440735
Spred2	Mouse	azoxystrobin	decreases expression	ISO	RGD:1319580	6480464	azoxystrobin results in decreased expression of SPRED2 mRNA	CTD	PMID:33512557
Spred2	Mouse	benzo[a]pyrene	decreases expression	EXP		6480464	Benzo(a)pyrene results in decreased expression of SPRED2 mRNA	CTD	PMID:19770486
Spred2	Mouse	benzo[a]pyrene	increases expression	ISO	RGD:1319580	6480464	Benzo(a)pyrene results in increased expression of SPRED2 mRNA	CTD	PMID:32234424
Spred2	Mouse	benzo[a]pyrene diol epoxide I	affects expression	ISO	RGD:1319580	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SPRED2 mRNA	CTD	PMID:20382639
Spred2	Mouse	benzo[a]pyrene diol epoxide I	decreases expression	ISO	RGD:1319580	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SPRED2 mRNA	CTD	PMID:19150397
Spred2	Mouse	benzoates	decreases expression	ISO	RGD:1319580	6480464	Benzoates analog results in decreased expression of SPRED2 mRNA	CTD	PMID:29472718
Spred2	Mouse	bis(2-ethylhexyl) phthalate	decreases expression	EXP		6480464	Diethylhexyl Phthalate results in decreased expression of SPRED2 mRNA	CTD	PMID:19850644
Spred2	Mouse	bis(2-ethylhexyl) phthalate	multiple interactions	EXP		6480464	PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SPRED2 mRNA]	CTD	PMID:19850644
Spred2	Mouse	bisphenol A	decreases expression	ISO	RGD:1309304	6480464	bisphenol A results in decreased expression of SPRED2 mRNA	CTD	PMID:25181051\|PMID:32145629
Spred2	Mouse	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of SPRED2 mRNA	CTD	PMID:32156529
Spred2	Mouse	bisphenol A	multiple interactions	ISO	RGD:1319580	6480464	[bisphenol A co-treated with Fulvestrant] results in decreased methylation of SPRED2 gene	CTD	PMID:31601247
Spred2	Mouse	bisphenol A	increases methylation	ISO	RGD:1309304	6480464	bisphenol A results in increased methylation of SPRED2 gene	CTD	PMID:28505145
Spred2	Mouse	bisphenol F	increases expression	EXP		6480464	bisphenol F results in increased expression of SPRED2 mRNA	CTD	PMID:38685157
Spred2	Mouse	bisphenol F	multiple interactions	ISO	RGD:1319580	6480464	[bisphenol F co-treated with Fulvestrant] results in increased methylation of SPRED2 gene	CTD	PMID:31601247
Spred2	Mouse	buta-1,3-diene	decreases expression	EXP		6480464	1,3-butadiene results in decreased expression of SPRED2 mRNA	CTD	PMID:29038090
Spred2	Mouse	butanal	decreases expression	ISO	RGD:1319580	6480464	butyraldehyde results in decreased expression of SPRED2 mRNA	CTD	PMID:26079696
Spred2	Mouse	cadmium atom	multiple interactions	ISO	RGD:1319580	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SPRED2 more ...	CTD	PMID:35301059
Spred2	Mouse	cadmium dichloride	increases expression	ISO	RGD:1319580	6480464	Cadmium Chloride results in increased expression of SPRED2 mRNA	CTD	PMID:38382870
Spred2	Mouse	cadmium dichloride	multiple interactions	ISO	RGD:1319580	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SPRED2 more ...	CTD	PMID:35301059
Spred2	Mouse	cadmium dichloride	decreases expression	ISO	RGD:1319580	6480464	Cadmium Chloride results in decreased expression of SPRED2 mRNA	CTD	PMID:38568856
Spred2	Mouse	caffeine	increases phosphorylation	ISO	RGD:1319580	6480464	Caffeine results in increased phosphorylation of SPRED2 protein	CTD	PMID:35688186
Spred2	Mouse	carbamazepine	affects expression	ISO	RGD:1319580	6480464	Carbamazepine affects the expression of SPRED2 mRNA	CTD	PMID:25979313
Spred2	Mouse	carbon nanotube	decreases expression	EXP		6480464	Nanotubes, Carbon results in decreased expression of SPRED2 mRNA	CTD	PMID:25620056
Spred2	Mouse	CGP 52608	multiple interactions	ISO	RGD:1319580	6480464	CGP 52608 promotes the reaction [RORA protein binds to SPRED2 gene]	CTD	PMID:28238834
Spred2	Mouse	choline	multiple interactions	EXP		6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ...	CTD	PMID:20938992
Spred2	Mouse	coumestrol	decreases expression	ISO	RGD:1319580	6480464	Coumestrol results in decreased expression of SPRED2 mRNA	CTD	PMID:19167446
Spred2	Mouse	coumestrol	multiple interactions	ISO	RGD:1319580	6480464	[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SPRED2 mRNA	CTD	PMID:19167446
Spred2	Mouse	crocidolite asbestos	affects expression	ISO	RGD:1319580	6480464	Asbestos, Crocidolite affects the expression of SPRED2 mRNA	CTD	PMID:17331233
Spred2	Mouse	cyclosporin A	increases expression	ISO	RGD:1319580	6480464	Cyclosporine results in increased expression of SPRED2 mRNA	CTD	PMID:20106945
Spred2	Mouse	DDT	decreases methylation	ISO	RGD:1309304	6480464	DDT results in decreased methylation of SPRED2 gene	CTD	PMID:31682807
Spred2	Mouse	deguelin	increases expression	ISO	RGD:1319580	6480464	deguelin results in increased expression of SPRED2 mRNA	CTD	PMID:33512557
Spred2	Mouse	dibutyl phthalate	increases expression	EXP		6480464	Dibutyl Phthalate results in increased expression of SPRED2 mRNA	CTD	PMID:21266533
Spred2	Mouse	dicrotophos	increases expression	ISO	RGD:1319580	6480464	dicrotophos results in increased expression of SPRED2 mRNA	CTD	PMID:28302478
Spred2	Mouse	diethylstilbestrol	decreases expression	EXP		6480464	Diethylstilbestrol results in decreased expression of SPRED2 mRNA	CTD	PMID:15171707
Spred2	Mouse	divanadium pentaoxide	affects expression	ISO	RGD:1319580	6480464	vanadium pentoxide affects the expression of SPRED2 mRNA	CTD	PMID:17459161
Spred2	Mouse	dorsomorphin	multiple interactions	ISO	RGD:1319580	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Spred2	Mouse	doxorubicin	decreases expression	ISO	RGD:1319580	6480464	Doxorubicin results in decreased expression of SPRED2 mRNA	CTD	PMID:29803840
Spred2	Mouse	Enterolactone	multiple interactions	ISO	RGD:1319580	6480464	[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SPRED2 mRNA	CTD	PMID:19167446
Spred2	Mouse	epoxiconazole	increases expression	EXP		6480464	epoxiconazole results in increased expression of SPRED2 mRNA	CTD	PMID:35436446
Spred2	Mouse	ethanol	affects splicing	EXP		6480464	Ethanol affects the splicing of SPRED2 mRNA	CTD	PMID:30319688
Spred2	Mouse	ethanol	affects expression	EXP		6480464	Ethanol affects the expression of SPRED2 mRNA	CTD	PMID:30319688
Spred2	Mouse	folic acid	multiple interactions	EXP		6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ...	CTD	PMID:20938992
Spred2	Mouse	folic acid	decreases expression	EXP		6480464	Folic Acid results in decreased expression of SPRED2 mRNA	CTD	PMID:25629700
Spred2	Mouse	formaldehyde	decreases expression	ISO	RGD:1319580	6480464	Formaldehyde results in decreased expression of SPRED2 mRNA	CTD	PMID:20655997
Spred2	Mouse	FR900359	decreases phosphorylation	ISO	RGD:1319580	6480464	FR900359 results in decreased phosphorylation of SPRED2 protein	CTD	PMID:37730182
Spred2	Mouse	fulvestrant	multiple interactions	ISO	RGD:1319580	6480464	[bisphenol A co-treated with Fulvestrant] results in decreased methylation of SPRED2 gene; [bisphenol F co-treated more ...	CTD	PMID:31601247
Spred2	Mouse	inulin	multiple interactions	EXP		6480464	[perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SPRED2 mRNA	CTD	PMID:36331819
Spred2	Mouse	isotretinoin	increases expression	ISO	RGD:1319580	6480464	Isotretinoin results in increased expression of SPRED2 mRNA	CTD	PMID:20436886
Spred2	Mouse	L-methionine	multiple interactions	EXP		6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ...	CTD	PMID:20938992
Spred2	Mouse	lead(0)	decreases expression	ISO	RGD:1319580	6480464	Lead results in decreased expression of SPRED2 mRNA	CTD	PMID:19921347
Spred2	Mouse	leflunomide	increases expression	ISO	RGD:1319580	6480464	leflunomide results in increased expression of SPRED2 mRNA	CTD	PMID:28988120
Spred2	Mouse	methyl methanesulfonate	decreases expression	ISO	RGD:1319580	6480464	Methyl Methanesulfonate results in decreased expression of SPRED2 mRNA	CTD	PMID:23649840
Spred2	Mouse	methylmercury chloride	increases expression	ISO	RGD:1319580	6480464	methylmercuric chloride results in increased expression of SPRED2 mRNA	CTD	PMID:28001369
Spred2	Mouse	N,N-diethyl-m-toluamide	multiple interactions	ISO	RGD:1309304	6480464	[Permethrin co-treated with DEET] results in decreased methylation of SPRED2 gene	CTD	PMID:33148267
Spred2	Mouse	nitrofen	decreases expression	ISO	RGD:1309304	6480464	nitrofen results in decreased expression of SPRED2 mRNA	CTD	PMID:23982388\|PMID:26720608
Spred2	Mouse	ozone	multiple interactions	EXP		6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ...	CTD	PMID:34911549
Spred2	Mouse	paracetamol	affects expression	EXP		6480464	Acetaminophen affects the expression of SPRED2 mRNA	CTD	PMID:17562736
Spred2	Mouse	paracetamol	decreases expression	ISO	RGD:1309304	6480464	Acetaminophen results in decreased expression of SPRED2 mRNA	CTD	PMID:33387578
Spred2	Mouse	paracetamol	increases expression	ISO	RGD:1319580	6480464	Acetaminophen results in increased expression of SPRED2 mRNA	CTD	PMID:29067470
Spred2	Mouse	paracetamol	decreases expression	ISO	RGD:1319580	6480464	Acetaminophen results in decreased expression of SPRED2 mRNA	CTD	PMID:21420995
Spred2	Mouse	perfluorooctane-1-sulfonic acid	multiple interactions	EXP		6480464	[perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SPRED2 mRNA	CTD	PMID:36331819
Spred2	Mouse	permethrin	multiple interactions	ISO	RGD:1309304	6480464	[Permethrin co-treated with DEET] results in decreased methylation of SPRED2 gene	CTD	PMID:33148267
Spred2	Mouse	pirinixic acid	decreases expression	EXP		6480464	pirinixic acid results in decreased expression of SPRED2 mRNA	CTD	PMID:17950772
Spred2	Mouse	potassium chromate	increases expression	ISO	RGD:1319580	6480464	potassium chromate(VI) results in increased expression of SPRED2 mRNA	CTD	PMID:22079256
Spred2	Mouse	potassium chromate	multiple interactions	ISO	RGD:1319580	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SPRED2 mRNA	CTD	PMID:22079256
Spred2	Mouse	potassium dichromate	decreases expression	EXP		6480464	Potassium Dichromate results in decreased expression of SPRED2 mRNA	CTD	PMID:23608068
Spred2	Mouse	rac-lactic acid	increases expression	ISO	RGD:1319580	6480464	Lactic Acid results in increased expression of SPRED2 mRNA	CTD	PMID:30851411
Spred2	Mouse	SB 431542	multiple interactions	ISO	RGD:1319580	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Spred2	Mouse	silver atom	increases expression	ISO	RGD:1319580	6480464	Silver results in increased expression of SPRED2 mRNA	CTD	PMID:28959546
Spred2	Mouse	silver atom	increases expression	EXP		6480464	Silver results in increased expression of SPRED2 mRNA	CTD	PMID:27131904
Spred2	Mouse	silver(0)	increases expression	ISO	RGD:1319580	6480464	Silver results in increased expression of SPRED2 mRNA	CTD	PMID:28959546
Spred2	Mouse	silver(0)	increases expression	EXP		6480464	Silver results in increased expression of SPRED2 mRNA	CTD	PMID:27131904
Spred2	Mouse	sodium arsenite	increases expression	ISO	RGD:1319580	6480464	sodium arsenite results in increased expression of SPRED2 mRNA	CTD	PMID:38568856
Spred2	Mouse	sulforaphane	increases expression	ISO	RGD:1319580	6480464	sulforaphane results in increased expression of SPRED2 mRNA	CTD	PMID:31838189
Spred2	Mouse	sunitinib	increases expression	ISO	RGD:1319580	6480464	Sunitinib results in increased expression of SPRED2 mRNA	CTD	PMID:31533062
Spred2	Mouse	tert-butyl hydroperoxide	increases expression	ISO	RGD:1319580	6480464	tert-Butylhydroperoxide results in increased expression of SPRED2 mRNA	CTD	PMID:15336504
Spred2	Mouse	thifluzamide	increases expression	ISO	RGD:1319580	6480464	thifluzamide results in increased expression of SPRED2 mRNA	CTD	PMID:33512557
Spred2	Mouse	thiram	increases expression	ISO	RGD:1319580	6480464	Thiram results in increased expression of SPRED2 mRNA	CTD	PMID:38568856
Spred2	Mouse	titanium dioxide	decreases methylation	EXP		6480464	titanium dioxide results in decreased methylation of SPRED2 gene; titanium dioxide results in decreased methylation more ...	CTD	PMID:35295148
Spred2	Mouse	titanium dioxide	increases methylation	EXP		6480464	titanium dioxide results in increased methylation of SPRED2 gene	CTD	PMID:35295148
Spred2	Mouse	trichostatin A	decreases expression	ISO	RGD:1319580	6480464	trichostatin A results in decreased expression of SPRED2 mRNA	CTD	PMID:24935251\|PMID:26272509
Spred2	Mouse	trichostatin A	multiple interactions	ISO	RGD:1319580	6480464	[NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Spred2	Mouse	trovafloxacin	multiple interactions	EXP		6480464	[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of SPRED2 mRNA	CTD	PMID:18930950
Spred2	Mouse	tunicamycin	decreases expression	ISO	RGD:1319580	6480464	Tunicamycin results in decreased expression of SPRED2 mRNA	CTD	PMID:29453283
Spred2	Mouse	urethane	increases expression	ISO	RGD:1319580	6480464	Urethane results in increased expression of SPRED2 mRNA	CTD	PMID:28818685
Spred2	Mouse	valproic acid	decreases methylation	ISO	RGD:1319580	6480464	Valproic Acid results in decreased methylation of SPRED2 gene	CTD	PMID:29154799
Spred2	Mouse	valproic acid	increases expression	ISO	RGD:1319580	6480464	Valproic Acid results in increased expression of SPRED2 mRNA	CTD	PMID:24935251
Spred2	Mouse	vinclozolin	decreases expression	ISO	RGD:1309304	6480464	vinclozolin results in decreased expression of SPRED2 mRNA	CTD	PMID:23034163
Spred2	Mouse	zinc atom	multiple interactions	ISO	RGD:1319580	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of SPRED2 mRNA	CTD	PMID:18593933
Spred2	Mouse	zinc(0)	multiple interactions	ISO	RGD:1319580	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of SPRED2 mRNA	CTD	PMID:18593933

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	negative regulation of epithelial to mesenchymal transition	involved_in	IDA		2290270	PMID:25576668	UniProt	PMID:25576668
Spred2	Mouse	negative regulation of ERK1 and ERK2 cascade	involved_in	IBA	PANTHER:PTN000128438\|MGI:2150016\|MGI:2150019\|FB:FBgn0020767\|MGI:2142186	2290270		GO_Central	GO_REF:0000033
Spred2	Mouse	negative regulation of ERK1 and ERK2 cascade	involved_in	IDA		2290270	PMID:29501879	UniProt	PMID:29501879
Spred2	Mouse	negative regulation of intracellular signal transduction	involved_in	IDA		2290270	PMID:20736167	BHF-UCL	PMID:20736167
Spred2	Mouse	negative regulation of lens fiber cell differentiation	involved_in	IDA		2290270	PMID:29501879	UniProt	PMID:29501879
Spred2	Mouse	negative regulation of MAPK cascade	acts_upstream_of_or_within	IMP		2290270	PMID:12646235	MGI	PMID:12646235
Spred2	Mouse	negative regulation of peptidyl-threonine phosphorylation	involved_in	ISO	UniProtKB:Q7Z698	2290270		GO_Central	GO_REF:0000119
Spred2	Mouse	negative regulation of transforming growth factor beta receptor signaling pathway	involved_in	IDA		2290270	PMID:25576668	UniProt	PMID:25576668
Spred2	Mouse	positive regulation of DNA damage response, signal transduction by p53 class mediator	involved_in	IDA		2290270	PMID:20736167	BHF-UCL	PMID:20736167

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	cytoplasmic vesicle	located_in	IDA		2290270	PMID:15580519	MGI	PMID:15580519
Spred2	Mouse	plasma membrane	is_active_in	IBA	PANTHER:PTN002598102\|UniProtKB:P50552\|RGD:1308735\|MGI:2142186\|MGI:2150019\|dictyBase:DDB_G0289541\|UniProtKB:Q8N8S7	2290270		GO_Central	GO_REF:0000033
Spred2	Mouse	plasma membrane	located_in	IDA		2290270	PMID:12646235	MGI	PMID:12646235
Spred2	Mouse	transport vesicle membrane	located_in	IEA	UniProtKB-SubCell:SL-0245	2290270		UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	protein binding	enables	IPI	UniProtKB:Q14596	2290270	PMID:19822672	UniProt	PMID:19822672
Spred2	Mouse	protein binding	enables	IPI	PR:P05532	2290270	PMID:12646235	MGI	PMID:12646235
Spred2	Mouse	protein binding	enables	IPI	UniProtKB:Q63572	2290270	PMID:17974561	UniProt	PMID:17974561
Spred2	Mouse	protein kinase binding	enables	IBA	PANTHER:PTN000128438\|UniProtKB:Q7Z699\|MGI:2150019\|UniProtKB:Q7Z698\|MGI:2150016	2290270		GO_Central	GO_REF:0000033
Spred2	Mouse	protein kinase binding	enables	ISO	UniProtKB:Q7Z698	2290270		GO_Central	GO_REF:0000119
Spred2	Mouse	protein kinase binding	enables	IPI	UniProtKB:Q61214	2290270	PMID:20736167	BHF-UCL	PMID:20736167
Spred2	Mouse	protein serine/threonine kinase inhibitor activity	enables	IDA		2290270	PMID:20736167	BHF-UCL	PMID:20736167
Spred2	Mouse	stem cell factor receptor binding	enables	IPI	PR:P05532	2290270	PMID:12646235	MGI	PMID:12646235

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	Jak-Stat signaling pathway		IEA		6907045		KEGG	mmu:04630

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Spred2	Mouse	abnormal definitive hematopoiesis		IAGP		5509061		MGI	PMID:14981116
Spred2	Mouse	abnormal kidney morphology		IEA		5509061		MGI
Spred2	Mouse	abnormal liver morphology		IEA		5509061		MGI
Spred2	Mouse	abnormal retina morphology		IEA		5509061		MGI
Spred2	Mouse	abnormal skin morphology		IEA		5509061		MGI
Spred2	Mouse	abnormal vitreous body morphology		IEA		5509061		MGI
Spred2	Mouse	cataract		IEA		5509061		MGI
Spred2	Mouse	decreased body length		IAGP		5509061		MGI	PMID:15946934
Spred2	Mouse	decreased body weight		IAGP		5509061		MGI	PMID:15946934
Spred2	Mouse	decreased litter size		IAGP		5509061		MGI	PMID:15946934
Spred2	Mouse	decreased long bone epiphyseal plate size		IAGP		5509061		MGI	PMID:15946934
Spred2	Mouse	decreased mean corpuscular volume		IEA		5509061		MGI
Spred2	Mouse	decreased width of hypertrophic chondrocyte zone		IAGP		5509061		MGI	PMID:15946934
Spred2	Mouse	disproportionate dwarf		IAGP		5509061		MGI	PMID:15946934
Spred2	Mouse	enlarged kidney		IEA		5509061		MGI
Spred2	Mouse	enlarged lymph nodes		IEA		5509061		MGI
Spred2	Mouse	enlarged spleen		IEA		5509061		MGI
Spred2	Mouse	enlarged stomach		IEA		5509061		MGI
Spred2	Mouse	increased brain size		IEA		5509061		MGI
Spred2	Mouse	increased circulating bilirubin level		IEA		5509061		MGI
Spred2	Mouse	increased megakaryocyte cell number		IAGP		5509061		MGI	PMID:14981116
Spred2	Mouse	increased megakaryocyte cell number		IAGP		5509061		MGI	PMID:15946934
Spred2	Mouse	increased red blood cell distribution width		IEA		5509061		MGI
Spred2	Mouse	short tibia		IAGP		5509061		MGI	PMID:15946934

#	Reference Title	Reference Citation
1.	Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.	Ko MS, etal., Development 2000 Apr;127(8):1737-49.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	MGD IEA	MGD IEA
4.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:8889548	PMID:10349636	PMID:10512203	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11493923	PMID:12477932	PMID:12520002	PMID:12646235	PMID:12904583
PMID:14610273	PMID:14981116	PMID:15184877	PMID:15489334	PMID:15580519	PMID:15683364	PMID:15840001	PMID:15946934	PMID:16141072	PMID:16141073	PMID:16378760	PMID:16919269
PMID:17438136	PMID:17967808	PMID:17974561	PMID:18287559	PMID:18799693	PMID:18799725	PMID:19521500	PMID:19822672	PMID:20736167	PMID:20882678	PMID:20934536	PMID:21199868
PMID:21267068	PMID:21873635	PMID:22868447	PMID:25275324	PMID:25576668	PMID:25690936	PMID:26075267	PMID:26362256	PMID:26496610	PMID:27869219	PMID:28070119	PMID:28489004
PMID:28705898	PMID:28993690	PMID:29317674	PMID:29501879	PMID:29706577	PMID:30022248	PMID:30723473	PMID:30771306	PMID:31923414	PMID:32325033	PMID:32452519	PMID:32554809
PMID:32841583	PMID:33020583	PMID:34626534	PMID:36704943	PMID:38355793	PMID:38391903	PMID:38892460

Spred2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	19,874,442 - 19,974,026 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	19,874,375 - 19,974,026 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	19,924,442 - 20,024,026 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	19,924,375 - 20,024,026 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	19,824,445 - 19,922,600 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	19,824,445 - 19,922,600 (+)	NCBI		MGSCv36	mm8
Celera	11	22,066,219 - 22,164,240 (+)	NCBI		Celera
Cytogenetic Map	11	A3.1	NCBI
cM Map	11	12.79	NCBI

SPRED2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	65,307,175 - 65,432,599 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	65,310,851 - 65,432,637 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	65,537,985 - 65,659,733 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	65,391,489 - 65,512,815 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	65,449,636 - 65,570,961	NCBI
Celera	2	65,384,626 - 65,506,328 (-)	NCBI		Celera
Cytogenetic Map	2	p14	NCBI
HuRef	2	65,272,227 - 65,393,668 (-)	NCBI		HuRef
CHM1_1	2	65,469,340 - 65,590,964 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	65,316,846 - 65,442,268 (-)	NCBI		T2T-CHM13v2.0

Spred2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	98,350,577 - 98,452,143 (+)	NCBI		GRCr8
mRatBN7.2	14	94,149,210 - 94,250,787 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	94,148,837 - 94,249,162 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	98,490,319 - 98,591,853 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	99,730,616 - 99,832,149 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	96,197,976 - 96,299,521 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	104,268,362 - 104,290,206 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	104,191,517 - 104,290,456 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	104,002,472 - 104,024,316 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	100,775,869 - 100,797,717 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	100,717,198 - 100,818,203 (+)	NCBI
Celera	14	93,246,801 - 93,268,145 (+)	NCBI		Celera
Cytogenetic Map	14	q22	NCBI

Spred2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	19,133,568 - 19,250,118 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	19,133,568 - 19,250,118 (+)	NCBI	ChiLan1.0	ChiLan1.0

SPRED2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	60,961,140 - 61,083,663 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	60,965,098 - 61,087,614 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	65,380,608 - 65,503,139 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	66,503,260 - 66,624,840 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	66,503,260 - 66,624,840 (-)	Ensembl	panpan1.1		panPan2

SPRED2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	64,764,275 - 64,815,937 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	64,764,311 - 64,867,009 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	64,648,640 - 64,763,412 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	65,771,737 - 65,886,366 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	65,773,399 - 65,886,224 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	65,450,264 - 65,564,843 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	65,758,109 - 65,872,866 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	66,053,709 - 66,168,347 (-)	NCBI		UU_Cfam_GSD_1.0

Spred2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	18,400,544 - 18,517,746 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936491	10,053,545 - 10,170,976 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936491	10,053,546 - 10,170,950 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SPRED2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	76,523,589 - 76,649,651 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	76,527,646 - 76,649,652 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	80,324,906 - 80,445,715 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SPRED2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	41,574,244 - 41,699,897 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	41,640,758 - 41,700,009 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	70,192,808 - 70,318,539 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Spred2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624762	8,109,157 - 8,240,543 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624762	8,109,159 - 8,240,543 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Spred2
3457 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	1397
Count of miRNA genes:	589
Interacting mature miRNAs:	677
Transcripts:	ENSMUST00000093298, ENSMUST00000093299, ENSMUST00000123036
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1302171	Pgia28_m	proteoglycan induced arthritis 28 (mouse)			Not determined		11	8906097	42906218	Mouse
1357720	Kidpq1_m	kidney weight percentage QTL 1 (mouse)			Not determined		11	12268637	68500330	Mouse
1357722	Vtbt11_m	vertebral trabecular bone trait 11 (mouse)			Not determined		11	1	23880487	Mouse
1357851	Scfq3_m	subcutaneous fat pad weight QTL 3 (mouse)			Not determined		11	12268637	68500330	Mouse
27226762	Feml21_m	femur length 21, 16 week (mouse)					11	11750000	65990826	Mouse
1301765	Skull15_m	skull morphology 15 (mouse)			Not determined		11	1	25976374	Mouse
4141470	Egq4_m	early growth QTL 4 (mouse)			Not determined			12268637	68500330	Mouse
13524844	Ppiq9_m	prepulse inhibition QTL 9 (mouse)					11	9049997	35077325	Mouse
4142109	W10q2_m	weight 10 weeks QTL 2 (mouse)			Not determined			12268637	68500330	Mouse
1300661	Lmr6_m	leishmaniasis resistance 6 (mouse)			Not determined		11	1	25976374	Mouse
13208559	Wght10_m	weight 10 (mouse)					11	3950000	88890826	Mouse
10412216	Eae44_m	experimental allergic encephalomyelitis susceptibility 44 (mouse)			Not determined		11	12268637	39950840	Mouse
13208558	Lgth12_m	body length 12 (mouse)					11	3950000	94890826	Mouse
26884401	Huml4_m	humerus length 4, 10 week (mouse)					11	11550000	68490826	Mouse
10053687	Eae6_m	susceptibility to experimental allergic encephalomyelitis 6 (mouse)			Not determined		11	17781966	68500330	Mouse
27226798	Scvln18_m	sacral vertebrae length 2, 16 week (mouse)					11	3250000	60690826	Mouse
4141582	Lgaq1_m	late growth adjusted QTL 1 (mouse)			Not determined			12268637	68500330	Mouse
4141966	Tailq1_m	tail length QTL 1 (mouse)			Not determined			12268637	68500330	Mouse
1300768	Tshp9_m	tooth shape 9 (mouse)			Not determined		11	1	25976374	Mouse
10053676	Eae44a_m	experimental allergic encephalomyelitis susceptibility 44a (mouse)			Not determined		11	4507896	21379532	Mouse
1558945	Orgwq8_m	organ weight QTL 8 (mouse)			Not determined		11	17056175	67078411	Mouse
4142216	Lgq1_m	late growth QTL 1 (mouse)			Not determined			12268637	68500330	Mouse
1300905	Scc6_m	colon tumor susceptibility 6 (mouse)			Not determined		11	6880277	89019734	Mouse
14746971	Manh70_m	mandible shape 70 (mouse)					11	19905890	53905890	Mouse
39128214	Lwq20_m	liver weight QTL 20 (mouse)					11	12268637	118022724	Mouse
26884446	Sklq10_m	skull length QTL 10, 10 week (mouse)					11	3250000	62890826	Mouse
4141047	Nilac1_m	nicotine induced locomotor activity 1 (mouse)			Not determined		11	9011780	43011942	Mouse
1559002	Lmrq4_m	Leishmania major resistance QTL 4 (mouse)			Not determined		11	12268637	69684947	Mouse
1300938	Bulb3_m	bulb size 3 (mouse)			Not determined		11	18578616	52578716	Mouse
1357518	Tgyl1_m	triglyceride level 1 (mouse)			Not determined		11	6880277	33916219	Mouse
4142308	W6q3_m	weight 6 weeks QTL 3 (mouse)			Not determined		11	12268637	68500330	Mouse
1357640	Orq2_m	ovulation rate QTL 2 (mouse)			Not determined		11	12268637	68500330	Mouse
1300599	Cocrb11_m	cocaine related behavior 11 (mouse)			Not determined		11	2670355	36671472	Mouse
1357437	Epfq4_m	epididymal fat pad weight QTL 4 (mouse)			Not determined		11	12268637	68500330	Mouse
27226741	Metcl5_m	metatarsal-calcaneal length 5, 5 week (mouse)					11	4650000	46290827	Mouse
1300990	Bits3_m	bitterness sensitivity 3 (mouse)			Not determined		11	8372121	42372260	Mouse
27226738	Metcl11_m	metatarsal-calcaneal length 11, 10 week (mouse)					11	8850000	61390826	Mouse
27226735	Metcl16_m	metatarsal-calcaneal length 16, 16 week (mouse)					11	5250000	35090827	Mouse
12801459	Leuf1_m	leukocyte filtration 1 (mouse)					11	18578616	52578716	Mouse
1300579	Thypr1_m	thymocyte proliferative response 1 (mouse)			Not determined		11	19282577	53282715	Mouse
10044008	Hbnr15_m	Heligmosomoides bakeri nematode resistance 15 (mouse)			Not determined		11	227052	34227232	Mouse
12801457	Intmrm2_m	intima/media ratio modifier 2 (mouse)					11	18578616	52578716	Mouse
12801460	Intim2_m	intima modifier 2 (mouse)					11	18578616	52578716	Mouse
27095909	Scvln6_m	sacral vertebrae length 2, 5 week (mouse)					11	3250000	44090827	Mouse
4141127	W3q4_m	weight 3 weeks QTL 4 (mouse)			Not determined			12268637	68500330	Mouse
4141894	Nidd6k_m	Nidd6 on KK-A (mouse)			Not determined			19124204	96897826	Mouse
13463479	Mchq19_m	mean corpuscular hemoglobin QTL 19 (mouse)					11	10951232	44951464	Mouse
27095904	Scvln12_m	sacral vertebrae length 2, 10 week (mouse)					11	3250000	34495048	Mouse
13463472	Mcvq15_m	mean corpuscular volume QTL 15 (mouse)					11	10951232	44951464	Mouse
26884453	Sklq16_m	skull length QTL 16, 16 week (mouse)					11	3250000	72690826	Mouse

RH126620

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	11	20,023,715 - 20,023,940	UniSTS	GRCm38
MGSCv37	11	19,923,718 - 19,923,943	UniSTS	GRCm37
Celera	11	22,165,357 - 22,165,582	UniSTS
Cytogenetic Map	11	A3.2	UniSTS
Whitehead/MRC_RH	11	374.99	UniSTS

C79158

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	50,376,134 - 50,376,294	UniSTS	GRCm38
GRCm38	11	20,023,639 - 20,023,799	UniSTS	GRCm38
MGSCv37	11	19,923,642 - 19,923,802	UniSTS	GRCm37
MGSCv37	X	47,729,311 - 47,729,471	UniSTS	GRCm37
Celera	11	22,165,281 - 22,165,441	UniSTS
Celera	X	37,809,635 - 37,809,795	UniSTS
Cytogenetic Map	11	A3.2	UniSTS

Spred2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	11	20,021,450 - 20,022,419	UniSTS	GRCm38
MGSCv37	11	19,921,453 - 19,922,422	UniSTS	GRCm37
Celera	11	22,163,093 - 22,164,062	UniSTS
Cytogenetic Map	11	A3.2	UniSTS
cM Map	11		UniSTS

Spred2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	11	A3.2	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	NM_033523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006514456	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006514457	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006514458	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_036156236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB063496	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK032859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK036430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK153700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK157817	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL645609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL672084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC030460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC040462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC051247	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC066013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000093298 ⟹ ENSMUSP00000090987

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	19,874,442 - 19,972,577 (+)	Ensembl
GRCm38.p6 Ensembl	11	19,924,442 - 20,022,577 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000093299 ⟹ ENSMUSP00000090988

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	19,874,375 - 19,974,026 (+)	Ensembl
GRCm38.p6 Ensembl	11	19,924,375 - 20,024,026 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000123036 ⟹ ENSMUSP00000115103

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	19,904,570 - 19,968,133 (+)	Ensembl
GRCm38.p6 Ensembl	11	19,954,570 - 20,018,133 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000249881 ⟹ ENSMUSP00000159978

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	11	19,929,570 - 19,974,026 (+)	Ensembl

RefSeq Acc Id:

NM_033523 ⟹ NP_277058

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	19,874,442 - 19,972,597 (+)	NCBI
GRCm38	11	19,924,442 - 20,022,597 (+)	NCBI
MGSCv37	11	19,824,445 - 19,922,600 (+)	RGD
Celera	11	22,066,219 - 22,164,240 (+)	RGD
cM Map	11		ENTREZGENE

Sequence:

show sequence

AATATGGAGTAAATCGGTGGAGTGGCGAGATGGGGCTCGGACGGGGCGCCCTGCACCGCCTCCCAGGCGCATCTCCCCCGGCCGCCGAGCACTACCCGGAACCCTGATTGGCCCGGTCCCCGGGGGCG
ACCCCGGCCCGGCCCCAGCGCAGCCGACTGCCCGCCCGCCGCCCGGAGCGTGCTTGTTTTTCTGCTGCTCTCCCCCTCCGGGTCCCCTTCCCAAATCTCGCCTCTGCACCCCCTCAGAGCCCCGGGGC
CGTGCCCGGCCGGCCCACGGCGTCCGCTGCCTGGTGTGCCCCTTCCCAGACCTCGCCCTGATCTCGGGGCTCTCCATTTCCCCGCCTGCCTCGGCGCCCCCTTCATCTCTAGCTCCCCCCCTCCACCA
CCAAATCAGGAGATGTCGGAGATGTGAAGAAGGGGGGCGAGCGCACAGGAAGATGAAGGGAGCCAGGCTGCATGCCGCGGGACAGGCGTCTAGGTGAACAAGAAAATGACCGAAGAAACACACCCGGA
CGATGACAGCTATATTGTGCGTGTCAAGGCTGTGGTTATGACCAGAGATGACTCCAGCGGGGGATGGTTCCCACAGGAAGGAGGCGGGATCAGTCGCGTCGGCGTGTGTAAGGTCATGCACCCTGAAG
GCAACGGACGAAGCGGCTTTCTCATCCATGGCGAGCGACAGAAAGACAAACTGGTGGTATTGGAATGCTATGTCAGAAAGGACTTGGTCTACACCAAAGCCAATCCGACGTTTCATCATTGGAAGGTT
GATAACAGGAAGTTTGGACTTACTTTCCAAAGTCCTGCAGATGCACGAGCCTTTGACAGGGGCGTGAGAAAAGCCATTGAAGACCTTATAGAAGGTTCAACGACCTCCTCTTCCACTCTCCATAACGA
AGCTGAGCTCGGAGACGATGACGTTTTCACGACAGCTACGGACAGTTCTTCTAATTCCTCGCAGAAGAGGGAGCCGACTACGAGGACAATCTCCTCCCCCACGTCCTGTGAGCACCGGAAGATTTATA
CCCTTGACCCATACCCCATGGACCATTACCACCCTGACCAGCGGTTGCCGCGGTCCTACCCCCAGGTCACCTTCCCAGAAGATGATGAAGAAATTGTACGCATCAACCCCCGAGAGAAGATCTGGATG
ACCGGTTATGAAGACTACCGGCACGCGCCGGTTCGCGGCAAATACTTAGACACCACAGAAGACGCGGACTCCTACGTGCGCTTCGCCAAGGGCGAAGTCCCCAAACACGAATATACCTATCCCTATGT
TGATTCTTCGGACTTCGGCTTCGGGGAGGATCCCAAAGGTAGTGTGATCAAGACACAGCCGCCCAGGGCCAAGTCCCGTCGGCGGAAGGAGAACGGCGAACGGTCGCGGTGTGTGTACTGCAGGGATA
TGTTTAATCACGAAGAGAACCGAAGGGGCCACTGCCAAGACGCGCCCGACGCCGTGAGAACTTGCATTCGCCGGGTGAGCTGTATGTGGTGCGCGGACAGCATGCTGTACCACTGTATGTCCGACCCC
GAGGGAGACTACACTGACCCTTGTTCGTGTGACACAAGCGATGAGAAGTTTTGCCTCCGGTGGATGGCTCTAATTGCCTTGTCTTTCCTGGCCCCTTGTATGTGCTGTTACCTGCCCCTCCGGGCCTG
CCACCGCTGTGGAGTGATGTGCAGGTGCTGTGGTGGGAAGCACAAAGCCGCCGCGTGACTCGGTTCCCCTACTTTCTGCTTCTCCATCCACGGCCACGGGCAACTTGTCTCTTGCGCACTCCCCCATC
CTCTCCCTGGTTCCCTTCCAACTCCAAAAGGCTAGGCCAATAAGAGGAGGCCAGGCTCTGTGGTCCCTTGGTGACATCATTCCAAACCTGGGGTAGCTGCCGCCCCCTGTGTCAGCCACATACCCCCT
CTCGCAGTGTTCTGAGGAAAGGAGCCTTCGGCATAGACTCGTGTATTTTACCAGCCTATAATCGTGCTGAGTGTTGGTTTCCTGCCCCTCCTTCCCACCTTTCTGGTTCTGCAGACTTGGAGGGGTTT
ATTGACTCTCCCCCCCCCTCCCCCGCTCTGTGACTTTTTTTTTTTTCTTCTCCCCATTGGGTTTGCCTGTCGCTAACTAGCATAGGTCCCACAGAGATGTGACAGAATGATGAAGCCGGCACCACAGC
ATGTTGTTATGTGAGGAGGCAATCTGGATAGCAAGCATGTACCACAAAACAGTAGTACTTTAACCCCTAATGCCACGTCTCCCCATCAGCTGCCGGTTTTGTCTTTAACCTGCTATCATCTCTTCTCC
TGCCCCTCCCTCCCCATGAATTAATTCACTAATGCAAAACAATCACTTTTTAAATGACTTTTTGAGCCTTAAATCCATATTCACTTGTGAGAATCAGGAAAGAATTCCTCGAGTTGCTTTGCATCCTC
TTGGACCAGGGCTTGCAAGGCGATTTGGGTTTCTGTGAGCTTGCCCAGTTGACCCGAAAAATAGGACTTTTTAGAATTGCATTGCCACTTCTAAAATCCTAGCAATACTTAGAATAACACATCAGTGA
GATAAATTTTACTCAATTATTTTACAAACCAAATTGAGTTATTCAAACACAAGCCAGTATTCTGTGAACAAGTTCCAGATGAAAAACACAGAAGTTGTGAATGAAGTTGTAGCCATTCCCTGCCCTGC
ACTATATTTTTCAGGGTGCATTTTAAATACTATTGATTCAAACAGTGGTGGCTTGCGTTTTTTTAGGTATATATTTTTGGTTAGTTTTTTGGGGGGGGTTGTTTTGTTTTTTTAATTTGAGGCTCAAT
TCTTCATTTATACTTGAAAAAAACAAGGCCATATGTAAAGAAAAAAAAAAACCCTC

hide sequence

RefSeq Acc Id:

XM_006514456 ⟹ XP_006514519

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	19,897,044 - 19,974,026 (+)	NCBI
GRCm38	11	19,947,045 - 20,024,026 (+)	NCBI

Sequence:

show sequence

TCTCTCTCTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTAGTTTTTCGAGACAGGGTTTCTCTGT
GTAGTCCTGGCTGTCCTGGAACTCACTTTGTAGACCAGGCTGGCCTCGAACTCAGAAATCCGCCTGTCTCTGCCTCCCGAGTGCTCCTGATTGTCTAACCCAGCTCCCCTTTGGCCTCTTGATGGTGC
TCCCCCTCCAAGCTGCATGCCTAGCTTTCCCTCCTGCCTGCTTTTTATTTGTATTTTGGATACTGGCTCAAGTTTCATAGCCCAGGCTAGACATAGCCCAGGCTAGACTCAGACTTGGATTCTTCCTG
CTGTCTTCACCTCTAGAGTCCCCACGTGTCAGGATTTCATGTTTTGCAGATCTCACTAATTGCCTTGAACTTGTAATTCTCCTGCATTGGCTTCAAGTGTGCCGCCATGCCCAGCTAACTCCTGTGGT
TACATGGTGACACTGAGATTTTGTTTTGACTTATTACAATGTCAGTTCTGTAAGGACTGGAACATTCTACCGAGGCTTAGCCTGCCCCTTTCTCCCGGCTGGCCTGGGTGCTATCCTGCCCCTGTCTT
TACTGACTGTGTGCGTGTACCCTTCAGTCTGACTTCTCCAGCTTGGCCTTTGCCAGGACTCAAGGTTTCTATGGTGACTCCACATGGGTGTGTGACAAGCACTTGGAGTGTTCCACCTAACTCCCAGC
CTTGCCACATGGGTGTGTGACAAGCATCTGATGCGTTCCACCTAACTACCAGCCTTGGCAGATGGCACTACCATTCTTTACTGTCACCCAGGTCCCAAATGTGTGCTATCTTTGCCATCCCACCCCCA
CTCCGTGTTGCCATGGACACCCTAGGCACTGTCTGCTGAGCTACATCCCCATCCCTTTGGGCGTCCATCTTCCCTGTATGGCCTTTTCATGCATAGTCATCCAGCTGAGGTATCTTGTTCCTCCACAG
CACACCCCAGACTTGCTTTCCTTGCCACTGGCCCTCTTGGCCAGGCTCCCAAAGTTTCTCATGTGAGCTTTGGCCGGAGGAGCACTGGGACGCCACGTCACTCTTGTCCTTGAGTACTTTTCTGCAGA
CTAGCCCCCAAGAATCCTTATGGAAATCACATCGCTCACCTCTCTTGTTGTTTAAAACTGGATAGGCATTTCCTGTGGGACTCAGCAGTGGCCGGAGTCATCACTAACTCCCAGTCTTCCTGGCTTGT
GTTGCACAGGCTCTCCTGTCTTCTGTGTAAGTCTGTGCCTCTCTTGCCTCAGGATTTTCACAGTTATCGTTGCTTCAGAAAGGGATACCGTTTCTCTGTTTGCCCTGTCAACTCCTCTCAGGTACCTG
TGCTGACCCTAGCCACCCTCTCTTATGTCACTAGACGTAAATATGTCTGGTCTGTTGGCTTATGTGTTCATGCTTGGTCTCTCTCTATATGAACAGGAGCATCTTTTGTGTATTTGTGCTCAGAAAGT
GCCTGGATGTAGTTAGTAGGTTGGGAAGCGTTGGCGAGGTGAGCAACGTAAGGAAGTTCAGAGCTGTCACCCCTGCTCACTCTCCTTTCTGACTAAAGGTCAAACTGCCTGTTGCTCCCAAAGATTTT
TGCATTCTAAGAAGCCATTTCCAGAGACCATGAGGAAACGAGGCCCTGCCAGGACAAGCTGAGTAAAAGCCCCTGGTCCTTTTTTGAGATGCCAGGTTCCTGTGAAAGCCTTTCCTCTGCCCATTCAG
TCACCCCAGAACAAACACTGCTGATGCGCTTAAAGTGGAAGTGACAAAACTGCTCCCCCTGAGTCCCCACTGTTAGTCTTTACTGTACTGGGGGTGGGGGGTGACACAGCACTGACCTTGTGGTTCTT
TGTAAACACTGACTCTGGCTTCTAGTTAAATGTAGTAAACTGGGCAGATGTGTGTATCTCTGCTGCTACGGCCCAACTCTAGCAAAATGGCAGAAAGGTGTAAAGTATGTAGCAACCAAAACCAAAGG
ACCAAAGGAGAAAGAGAATTCCCCAGAATAGTATCCCATACAGGAGGGAAGAAAGAGGCCCCAACTCCACAGCCACACATGGGAGCCCTGAGAGAGGACCAGTATTCCTAGAAGTATTAGCATGAACA
GCAAAGGATGCTCTTGACCCAAATCACAGAATGTTCCAGCCAGCTCTGGTCCCCATTTGTGGCTTAAACAATAAATTCATCATAGGAAGCAGCAAAAATAACCAAGGTTTTGTTGGTTTTTCTCCATA
CTGAGGATCTAACCCAGGACCTCCCATGGGCTAGGTAAATACTTAATTACTGAGGTAAGACTGCAGGCCACCTGGGTTTTGTTGTTGTTGTTTTCGGAGAAGGGTGCTTGGGATGGTGATATGAGGCT
GTCCTTGAACTCTTGATTCTCCTGCCTGTGCCTCCCACGTCCTGGGATCACAAGGATGTTGAGGTTTGGCTTTTGCTGTATATTGTAATGCTGAGTGTGGCTCCCAAAACCTGGTTGCCCCAGAGACG
AAATAGCCTGCCTGCACTTAGACCCAAATGACTATGTGACCTTGCCACCAAATTATTTCTGATTAGTAAATAAAGTGCCAACAGCCAGTAGCCGGGGAGAAGAGATGTAGGTGGGTTTTAGGGTTCCT
GAGCTTGGGGGTTGGAGAATGACCAGGGAGAAAAAGGTAAAAGAAAAAATGTCATCATAGGTCAGGAGTTAAAAAACATGGCCCCAAGGGCTGGCCAATCGAAGATTTTAATAACATAGAGGGTAGCT
ATCTGCCCAGCTCTAGTGCTGATCTAGAATGGGTTACCTTGTTGTAAATGAATGAATAGCCTCTCCCCAATTGCTGTCCAAAACACGCCACAGGAAGTTGGTGCAGAGACAGGCTGGTTCATCTTGGT
TTAGGCAGCTGAAGAAAAACTTTCCATTAGAGCAGAGAACTGACTCTCACTATAGATACTTAGTGTAGGGTTTAGTCTAAAGGAGACGTGTTCCAGGTCACAACCCGCTCAAGTTGCTATGGAGAAGT
CAGCATTGATTCCCTTATGTGGGCCGGAGTCATTACTTGTTGCTGTCTTGGCCAGTTTCTGATAGGCTTGGATCATTTTCAGGGTGTTCATGGGTAAATGCTTGAGGCTAGGGGCCGTGAGTCCCAGT
ACTATCACGGCCTGATGTCAAACCAAGGTGTTCTCATTCAAAACAAGGAGAGAGAAGTCACGTCTTTTTTTCCTCTTTCAGTTTTCTGAGGGCTGTGACTAAAACATCCTGGCCTGAACAGTTTCTTG
CATTCTTACTTAAAAGAAGACTCTGGCGCACAGCAGACCTCTTCTAGCTATCTTTAGTGGGCTGTGGGGTGTATGTGACTAGGAATTCAGCTGTGCTTACTACCACGGCTGCATAGCATACACGCTTG
GGTAGGACTTTAGAATAGCCTCCTGGGGCTCGGAGATCTAATTTTTCAAGTACATGGTATGTAAGAGTCTCTCCTCAGGTCCGTGCGCCTCCAGGACTTCTTGCACCAGAGGCCTGGAACTTCTTTGT
TTAAAAGCCACCACCCTCGGCCCTGGAAAGACAGCCGTGCCTTGCTTGGAGCAGACAGAAGGCTGACTTCCTTTCAGTCTTGTGTAGTTTGGCCTTAGCGTGCCTTTGGATTCTTTACTTCTCGAGTG
TGGCCCTGCACAGATCCATCTCTGTCTGGAGACTCAGCTGTGTGGTAGAACTGCCTCTTCCGTGTTTAAAACTTGGAGCTGCCTTTTGCCTTTGCTCAGAAAGTTGTGTTTTTTCCTCAGCTAATGTT
TTTTAGGGTTTCTGTCATTTACGGGCCCATACGGAGCTCAAAGCTGCATCCGATTCGGGAATGTCCACAGCCGGCGGCAGCCAGGTATACAGACCCGTGCGCCAAAGTTTGTCTTTTAGATAAGAATG
CAAGAACTGTTCTGGCAATACAAGTTTAGTCAAAGAAAGCCCTAGGGAAAGTGAAAGAAGAAAAAGATGTGACTTTCCTCTCCCTGTTTTGAACAGAAACACTAAGATGTGAGGAGGGCCAGCGGGTC
CGGGAGCTACAGTGTCTCTAGGCCTCTAGGCGTTTCTTGGCAGGGAGGAGGTTAGTTAGGTGGGTAGAATTCTGGGAACTCCTGGTGGAGAAAGGGGCGCCTCCCTCATCTTAAAGGACAGCAGGTTT
GGGTGTATGGGTATAGCATACACACCCATGTGGGCCAGGGGGAGAAACAGGAGTATTCACACTGCATGTTTTGTGTGTGCCTGTCACTTGCCCGAGGACTTGATCACATCATCCCATTCAATCCTCTT
AGTAACTTTTTTCCTATTGGGAGGAAAACCAAGTTAAGCTCTAAAACGTACTGAACCCAGGGCAATCTGACTTCAAGGCTCTAGGCCTGAGTGGGCTTTTCCCTCCACTAGAGCAAATGGATACTTGA
AGTGGGGAGGAGTAACGTGAAGAGGTAAAGTTTAGGGGGAAATGTGGCTTGGGACAGATGGGGAAAAGGATGCATCCGAGTGCTGAGCTAACTGCTCTGGACGCTTCAGGAAGCCATTGACAGTTTTT
AATGGGGGGTGACATGACCACAGCAGGTCTTCCAGCTGTACCTGTAAAAACATCTGAGTTCATCACTCCGTGCCAGACACTGTCCCCTGAGCCTGGCACCCTCATTCTAGCCTGTGAGGTAGGTGCTG
TGGATATCCGCTGTACCTGTTAATGAAAGTCAGTGGAAGTTTAGAGAGGGTAGAGGACAGAAGGAAACTGAGTATTGCTATGGGAGGTGAACTTGAGGTCAAAGGCAAAAAGGTCACTGGCGAAATCC
CTGAGCAATAATGAAGGCGGGAGTAGGGGGCTAGCAGGATAAGTGAGAGGCTGGGGTGTAGCTGAGGAGGCTGGGAGAGTCCGATGGCAGAGGCTTCAGATCTCCACCCTGTAAGATGCTAGTATTGA
TAAAAGTGGAAGAAGGGACAATTTCCTCCTTGGTACCTTCTCAACAAAATTGAAGAATCAGGCTGGAATGTTTTGCTCAAAGGTCAGACCGACAACTTTGAGTTAAGGGCAGTTGTCAGAGAGATTTA
CTCAGGATTCAACTTTAGACAGAAAATGTATGTGATGGCCGGGCAAAGGCGGGATACCTGGGGACTACAGAGCACTCTAATTCAAGGCTGAATAGAGTTCTAGATGTTTCGGCTGGTGATAGGGTCTG
GTTTTAATTAATTAATTAATTAATTTACTTATTTATTTTTCTAGCAATGATCAAAGAATAAATGTTTGCTTATTGACACTTCTAAAGGCCGAAAGGTTCAAGATCAGGTGGCGGAGTCCGGGAAGGAT
CTTACTGCTGCAAGTCAGTGCAGGGTACCACATGTCAAGACAGATGGCTAGCTCAGGTCTCTCCTGCTTTTATAAATCTCTAATGCACCCTGGGGTTCCTTTCCACTCCCTACCTTCAGATACCCTCG
CTTGTGACTTTGGGAATTAAATGTCTAGTAGTTGATAATCTGGAGAACACGCCGAGATGGTAGCAGAGGGACAGCTGGATAGGTGGTGGGTGACCTGAATTCTTGAAAGAGCTGAATGACGGAGAGAA
ATTACTGGGTCCCTGGGCATCTCTGTACACTTAAGATTGTCACTCGGGCCAACCAGCTTCGGCCTGACAGCCTTCCATTTTCCCCATTCAGGAAACAATTCAAATCACTATGGTTTTGGCTCAGGATG
TGGCTTAATTTTTGCCTAGCATCCATAAAACACTGAGTTTGACTTCCAGCAGTACATAAACCAGACACATAACTGGAATTGCAGTCCTTGGGAAGTGGAGGCAGAAATATGAGTTCAAGGTAATCTCT
GGTTATGTGGTGAGTGAGTTTGGAGCCTGCCAGGCTGCATACTACCCTGTCTAAAAACCAACATCAAAGCCCATCATGTAGTTGCCACGGAGTTTCCTGAGAAAGCCAGAAGTAGAGCAAGGTGAAAA
TACAACACGTGTTTTAAGTTTCTCCCGGTTTTAGTTGGTGCCTGGATTCATCCACTCACTGCTTCGCAGCATCTTTGTGTCTCTGCGTCTTTGTGGCTCTGCGGGGTCCCAGGGTGATAGCCAAACTT
AACAGTGGGAACCGTGGCACTCAGTAGGGCCAGGGCTGGCTGCCGGCAAGGGAGGTGTTTAACTTCCCCAGGGCTTAGGTAAAGGAAGCAGGCACTGATAAGAAAGCGTGTGAGTCTCAGCTTTAGCT
TTTTATGGGGGTCACTGTGAGAGGGAAGGTCCATTCACAAGCCTCCAGCCTTCACTCTGACAGTGGCTTCCTGCAGGGCCCCAGCCATCCTCTAAAAGCTGTGACCCCAGCCTGAGGAAGATGCAGGC
TGCAGCTCCTACACTCTCCTCTTAAGACTTGCTCAGTTACAGAGCTGTGTGGTTGGCGCTTGTTGGTCAGTTATTTGTTTGTTATTTTTTGTTGACAGAGGCTACCTGAGAGGAAATGAGAATTTTTA
GGTGAGCTCTTTTTTTTTGTTGTTTTGTTTTTTCGAGACAGGATTTTCTCTGTATAGCCCCGGCTGTCCTGGAACTCACTCTGTAGACCAGGCTGGCCTCGAACTCAGAAATCTGCCTGCCTCTGCCT
CCCGAGTGCTGGGATCAAAGGCGTGTGCCACCACGCCTGGCTAGGAAATGAGAATTTTAATTTTTTTTCTGCTTTTTTTGGTATTTTGAGACCTGGCCTTACTGTGTAAGTCCAGGCTGGCCTGAAAC
CTGCTCTACCTCCCAAGCCCTGGGATTAACCAGCCATGGCCATCATTTGATGCACGTTAGAAAACAAAACCAAGAAATGTTTCTGTGAGGGACACATCTCATCTTTAAGTTCATAAGACACGGGGAAA
GCCTTTTCCCAGATGTAGCCTTATTTACTGTTTATTTTTTAAAATTAAGAAAATTGGGGGTATTTTTAAATTTGTGTCACATGGGTGTTTGCCTGCATGTATGCTTGTGCACCATGGAGTGCCCACAG
AGGACGGAAGAGAGCGTTGGACTGTCTGGAACTGCAGTTACAGATGCTTGCCGTGTGGGTGCTAGGAATGGACCCTGGGTCTTACGTAAGAGCGGCCAGTGCCCTTGACCATTGAGCCATCTCTCCAG
CTCCTTACTGATTTTTTTTTTTTTTTTTTTTTTTTTTTTAAGATCAGTCTCACTTAAAACATTCGCCTGTCTATGTTAGGGATGAGAAATACAGGCTCGGAGAGTGATGCCACACCTTCCTGCTTCTT
GTCTGCAGTGGGCCAGGAGTGGACAAGAGGCATGAATGGATGAAGGGAGGTTTCGGAAAGAACAGTTCTGTACTGCATACTGTGTTTCTGTTGGCATGCCCATATGCAGCAGTGATCGATAAGATTAT
AGTGTAATTGAAAAAAAATCTCCATTACCAAGAAATGCTACCAGTCAGACCATACTTTGGGTAATGCTGGTGTAACCAAACCAACTCTAGTGCCAGTCACATAGAACTTTTAACACAGTATGCTGCAT
GTTACCAGGTGACCATGAAGACATGACTCATGGCGTCCTTTTGAGAAGAAAGTCTTCTCCCGGGACGCTTAGCTCTTGTTTCTGTTTGCTGACAAATGGCTATGCTTTGTATCTTCGCTTGTCTGAGA
GATTATTTGGGATATTCTTCAATATGCTTGCAAAAGGGAACCATAGACCAGGAAGCACCAGTAACGTTTCCTTATTTCTGGTAAGTCTCTTTATTTATAATAACTATTAAGGTAAAGGTTAAATGATT
AGTCAACAAATAGGTATTGGGTAAAATCACGCCTTTCAGCTTGGAGTTTGTGGGAAAGCGGTCAGGTGCAGGTGGACGGGGGAGCGGGACAGGCAGTTATAGTTCCCACCTCAGTTGTCCCTTTATCT
ATGTTAAGAGTTCTAAACGTGCTTGAGGGCTGGTGAGGTAGCTCAGCGAGCAGCTTAATGTCCTAGTGACCTGAGGGGGACCTCAGAGAAGGCTGGAAGGAGAGAAAGATCCCTGCAAGCGGTCCCTG
ACCTCCACATGCACTAAACAACCATATGGTTTAAAACACTTGCAATATAAAGGTGGTTGGTTCTGAGCAGGGTGGTGTTTATAACGTGCTCCTTCGTTTCCCTTGTTTCTGTGTCTGTTGCAATGACT
TTCTACAAGAAAAGCTACTAGCTGCCTGACCTTTGCCTTCTGAAAAGGAGCCGGGAAGGATCCCGTTTGAACTTGTGACATCTTGCCTACTGCAGGTAGAGCTGGTAGAATGACAAGTGACTCCTCCC
TGCTCCGAGCTGACCTGTGTTCACTTTCCTCCTCCTTTCCACTCCATGCCCGGCAGTCTACTAAACAACCCTCATGAGGATGAGAACTTGAGACTGTTCCTGGCTGGCTACTGAGCAGAGCTTGGTAA
TGAGTGGCTTCGTTCCGGAGAGTGGATCTCACGCAGACATCCAGTTTGTATCCTGGGGTTTGACTGTGATAGTTTTCCTCATTTCACCACACCACACTGGAGCCTACACTCAGGATTTCCTGCTAATG
GAGAACCTCCCCTCACATCTTCAGAGTAAACTTACTATGGGTATTTTAACTCGGCTTGGAAGGAAGCAGAATTGTCTGCACCTCCGAGTACCAGGAAAAAACTCAACAGAGGAATTACTGAGTTTCCC
CTAGCTTGACTGTATACAGCATCACAGAGAAGCTTAGCAAACAAGCAATGAAAAGGTGAATTTCGGGTATGATACATGAAGAGTTAATCTAAAACTATGAATTTGGGGACTTATAGAAGAGACATTAG
ACAGCCAATAGCAAAACAAACAGTTCCTTTTTTTGTTTGTGTGCGTGTGCATGCGGAAGTCAGGGCAGCTCTGAGCAGTTAGTTAGCTCATGCCTTCCACCTTGTCCAGGCAAGATCTCTCCTGTGGT
TTCTGGTGCTGCTCTGTACTGTGCCGAGCCCTTCAGGCTCGCTCCTAGCCCCCAACCCATGCTCCAGGCAGTTCCGACTACCTTCCATCTTGCAGTAGCAGTACTAGGGTTGCTGCTGAACACCACTG
CACCAGGCTTTATAAAGTGAGTTCCAGAAATAAAAGTCAGGCTTTTATAGCTACTGTCTTACCTGCTGAGCCATCTTCCAGGCCACCACTACCACGGCCTCTTCCTCCTCCTCCCCGCTTTAAATAGC
ATGCTAACTGATTAAAAGAGAAAATCATAGCTAGGACAAAATAGCTAACAACTGACTGGATCCAACTTTCTGTCCAATGGAAAAATATTGTAAGATTGTGGCTTGGGTAAGAAATATTTCTCATGCAC
AGTTGTTGGAAGCATCCTCTTTCTGGGAAGCAGTTTAGTTGTTTGTGTTCCTTACCCTCCCCTACTATGAGAATTTCTTCTGGAAAGGTAAAGATAAAATAATTCGGTTATATGAAGGACCCACGTAC
TGTGTAGCCATGGAAAAGGGGGCTGTCAGGGAACTGGTGTTGTGAGCTGTGATGTTGTGTTACGTTTTGCTTTGTTGTTTGAGACAAGGTCTCACTCTGTAGCCCAGGCTTGTCTTGAACTCACAGAG
ATATACATGCTGCCTCCTGAGTGCTAGGATTGAAGGTGTGTGCCACCATGCCCTGCTGGGGTGTTTGTTTTGTTTTAAGGATTTTGTTTTAATTATTTGTATGTCTCTGTGTGAGTTTGTGCTGCTGA
GTATTTTGTATAGAGGTCAGAGAAGGGCATTAGGTCCCCTGAACCTAGAGTTACCAGCAGTTGTAAACCACTGAAAGTAGGTTCTGAGAACCAAACTTGGGTCCTTTCCAAAAACAGTGTGTGCCCTT
AAGAGCTGCGTCATCTCACCAGCTCTTCAGGGAATTGTTGGTAATACAGAAATACAATATTGGGGTCAAAGAAAAGAAGATATGGAACTCTACCTGCGTGACAGGATCCAATGTGTATCACAAAATGT
GTATCACAAAAACATATCTGGAATATGGTGTTAGCACTGGCCATTGTCATCTGAGTGTTGTGTTGGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGCACCTGTGTGAGTATGATTA
CATGCTTGTGTGTAAATAATTTAAAATGCTATTCTGGAAAATTTATCACTGCCATATGGTATGTATGTATGTATGTATGTATGTATGATATATATACTGAAATGAGGTTTTGTCACTTAGCAAGAAGG
GCCACGCTACCAGAATTAACAAGGTCTAGTTGGGATGGTATATTGTATTAACTTGTGATGATAAAATTAATGCTTTCTTTTAGAAACCATAAAGGGGACCTATGCAAAACTTTAAGTAGTGCCCGTAT
AAGGACCATGCTGTCTTTGATGTGATCATGCCCCTGAAACTAGGCAGCTGAGACATCTCATTTGCAGGGTCATAAAGAGACTGGGCAGTTCATTCAGGATCAAAAAACTCACAGCAGAGGGTGGATTT
GAACTCAAGCAGTCTGGATCTAGTGTCCAGGCTATTAAGCCCCAGCATTTGATTCTGTTCATTGTGTGAACAGCAGTATCATTTCTGACCCGACTCAGCTTTACCTGAGCCGCTCTGCTGTGTACAGG
GAAGAGCTTTGACCCTGACAACAGGGAACCGGTCTCTGGGTATATAGAGCCGTTTTAGTTTTGTAAGATAGGCTTGTGGGAGGGTCCCGGGGAAGCCTTGCTATTTCTGAAAGCCCTTGCCTTTCCTG
GATTTTGCTGAGACTGGCTCTTGTTCATTCTCCCTGAAACGTTTCTGCCCAGCCCACCAGGCATTTCTGTAGGTTTGTAATCTTGCATGAGGCTTCTAGACCTAAGGCCTTAGAGGGGAATCCAAGCA
TGGGAAGGCAGTGACAGGAACCTGGGTACCCCCCAGCTCAACTAAGATCCCCACAATAAATATATCATTACCCCAAATGCTTGTGACTGGAAATGCTTTACTGTCTGGAAAAAATTGTATACATTGTA
TAATGTGATCATGGGGATGCATTGAGCCTGGTGTGGCCTTGGTGGGGACAGAGGGACATGGTTTTGTCTCTGGAACAGGGCCCAGTGTGAGTATGAGTATTACTGGCTGTTATGGGAGTAGGCTTGTT
TGTATAATAATAATTTTGAGGGATGTCTTTGTTAACATTAATGACTTTATGATAATTAGAAACAGTAAGAGTCTAGGAGTTGAGGGTATGGCTATGTCTTAGCAAAATGGTAAACATTGGGATGCCTA
GGACTTCCCTTAAGGCTGTAGAAAGAACTCTTAACACGACGGGCAGTGGTGGTGCACGCCTTTAATTGGGACTTCAGAGTCCAAGGCCAGCCTGGTCTACAGAGTGAGACAAGGACTAGGACTATACA
GAGAAACCGTGTGTGTGTGTGTGGGGGGGGCTCTTAACACATGAGTTTGAAAATATATAATTTTTAGTTATAAAAAAATAAAGATATATAAATTATATGAGGGGCTTTATAAATCTAAAAGAACAAAA
ATCGTCATTCTGTGAGTCATCTTGTTAGAAAATTCTTAAGGGAGGAGATAAAGAGATTTAGGGAGTGTAGATCATAGGTGATCTTATTTAGTTAAGTATTTTATTTATGTTTATAAAGAGGTGAATTT
TTAAGTTTAGGGTCAGCCTAAGACAGACTAAGGTTAGACTTAGGCGTGATGAAATGATAATTTCAGGACAGGGCCTCACTTAACTAGTTTATTGTCTGTCTTAATAAAGGTAGACGGATCTTTAAATT
TTTTTATAATGTTAAAAATGTATATTTGTTGTCATGGGTCATGGGATAGTGATTTATAAGATAATAAAAAAACTAGAGTAAATGACTAGATTGGTATGTAATGCTTAAAGAATTGACACAAGCAAGCA
GGACATGCAGAGAGATCTCTTAGAATAACAAACAAAATATAGACAGAAAAATCTCCGGAGGGGGGGGGGGGACAACAGAGAGAGAAGCAGACTGGAAAAGCTGTATTAAATAGAACACAGGTCTTCAG
CTTATACCCATGATTCGACTTGAAATCGTTCTTTTCTCTGCTCCCAGACACCCTTCTCTCAGAAGCCCTCTCTAAGCTGGGAGGCTGGTTGGTTCTTGGCAGGGATGGCTCTCAAATCTAAACTCAAG
AGTTGTTTCATACACACCTTATACCCATAGCCTAAGGCTAGCTTATGTAACATTTAAAATACTTTTCTACATTAAGCAGGGCATGATGGCTCACACCTAAGATCCTAACACTCTGGAGTTGAAAGCAG
GAGGATTGGAAATCCAAGGTCACCCTTGGCTACATAGCAGTTTGAGGCTAGCCTGTACCTGTTCTCAAACAGCAACAATAATAATTTTTTTTAGAACTTCCCACTTATGGTATGCCGTCAGTACTCAG
AAGGTTTCTGATTTTGAAGTGTACTGAGTTTGGAGTTTTCTTTTTTAGGAAAGTAAAGAGTTTCAACCCAGGGATTCAAGTTCTATAGTGAGAGACATTTCCAGACCCTTGAGTCTTGTCATCAGCCC
ACCTATGCTTACTGGTTTTGTTTGCCCACCTGATTGGTTGGTTGGTTGGTTGGGCTTTTGTTGTTGTGTTAGTTTAGTTTGTTTTTTCTTTTAATTTGATCTTAGTAGTCCTGGGTCTCTGATCCAGG
CCCGTATGAATGCTAAGCAAACTCTGTATCATTGACCCACACACTGTGGCCTCTAGCTTAACACATGGTTTCTTTAATAAACTTGCTTTGTTTAACAGGATTTAAAAGTGTACTTAATACAGTTTTAC
TCTATCTGTAGATTTGCTAGTTTCTTCAAAATCCATGTGTGGCAAAGACCTTCCAATGATTCAAGTTAGAGCAGTTCCATTTTTGTATCAAAAAGAAACACCGTCAGTGGCTGTCTGGACATGTACCT
TGCTGGGGATGGTGCCAGAGCCTGGGTAACCGCCTGGACTTCAATGAAGGGGGGTGGGGGGGCGCATTGCATTCCTCAGTGGGGAGGTGGAGGCCTAGAATCAACTTTCTAACATTTTTAAATGGATG
GGGGTTGGGACAAGGCAGAGCACAGGTACATACATGCCACAGGGTGTGTGTGGGTGGCAGGGGACAGCTTGTGAGAATCTGTTCTCTCCTTTCACCATGTGGGCCCAGGAGATCAAGCCCAGGCTGAC
AGGCTTGGAGTCAGCACCGAGCCATCTTGCTAGCTAGCGCCTCCATCTTTTCCTTAGGTATGAGAGAACCTTAGAAATCCATATTTGACAAGATTGACTCGTAGGCACTTTCTCATGGCTGCTGTTTC
ATTTAAAGCAAAGCTGACGTTGGGACCTTCTGTAAATTCTTCACAGATTAAAACAAAAAAAACAAAAGCAAATGTTTGTACAAGTGCACAAGAGGTGGGGTGGATTGGATATAGGATGCTTTTAGAAT
TAAGTCGGGTGTTTCAGAGGGTGCGGAGGAAAGAGGTGGGAAAGAGAAGAGATAGTGTAGTGCATCTTTTTATTGCTGTGTCTCAGGAAAGAGGATGAAGCAGCTCTTGGGTTGTTCTCCGGTCTGGC
CAGGTAAATTTTCTTAGTTACAGCAGAGTTAAGTCCCCCCACCCCCACCCAAAAAAAAGCGGAGAACTGGGACATCACAAGCCAGAGCCATGTGGACAGGCTGGCCAAGCCAGAAGACCTAGAGCTTC
AGTGGCCACTGGGCCTTCTACTAGGCCAGTAAACTGCAGAGTGAGCCCCCTCAGCCCATCTGCTGAGCCTGCTGAATGGTAGCAGCTGCTCCACTTTGCCTGTAGATGTTGGCTAAATTGGAGGCTTG
TGTTGACTGGCCAGGAGGGCAAAATTTACCTCTAAGCCAAGGAGCACTGGGAATATTGGGGTAGTCTGAGAAGCAGGACTGTCTGCTAATGAATGGATTGTATACTCAGGAGAAGTTCGTGAGTCCAA
TGGGAACGTGTTGACACATGTGAGTGCATATGTTAGAGAAAAATCACTCCCATCTCTGTGTTGCTGTAGTTGTTGGAGATCAAGAGACATCCCACAGATAAGAGCCCATGCTATAAGCCGTCTGTGGA
CAGACCTCCCCATGCCTTCACAGAAATGCATGGTAGAGGTGCTTCCTGGCTCCTTTCTGGCTTAAGAAGTCACCAGACATGGGGCTGTAAGCCTGTGGACCTGGCCATTTTACAGGGCACCAGGCTGG
GTGAAGAAACCTGGCCCACAGGGTCGTGTTGCCCCAACATCGTTTGTTGGACACAGATAATGTTTTTGTCCCCGCCCCAATGGGAGACACTCAATCTCTACCTCAAGGGCTTGGATTGAGTTTCGCAA
GCTTTATATTAGTAGGTGATTGAAACACTTGGCTGGATCGCAGCAGCCGTAGTGTGGTAACCTGTGTGGCACAAGCCTCCTGGGTGAGTCATAGTTAATGGTGGTTAGAGACTTACTGTCCTAGCTTT
TCAGTATTGGTGAAGCATATGTCTATATAGTTGTTTTTAGCTTGACAACCTAGATCTAAATAGGAGATATGGTGGTTTGGTTTGGTTTGGTTTTTTTCAAAACAGGGTTTCTCTGTATAGCCCTGGCC
GTCCTGGAACTCACTCTGTAGACCAGGCTGGCCTCGAATTTAGAAATCCGCCTGCCTCTGCCTCCCAAGTGCTGGGATTAAAGGCGTGTGCCACCACCTCCCGGCTCTGAATTTGTTTTAATCAAGTA
CTGTAGTGACCCCCTCCATTCAATGTGCTCGCAAATGTCTTGCACTCCGTGAGATTTTGTTAGGTTCAGAAATAACTTAGAAGCATTTATGGTATATTTTACATTTTTCGTGTAAGTTTTCTTTTATA
GGCCCCATATTGAGCATGTTTGCCTGTCGCTCTCTAGTATATAAACCGGGAACTGGGTGGACTTAACCATTTCTTTGTGCAAAAGCCAGCAATTCAGTCAGGCCTTCTTGTCATTAGCCGTGGAAAAT
GAGATACTTCTGGCAGGAGTCCATGCTGTGGAGGGATGGCCAACCCCACCAAAGAGAAAGCAACCACAGAAGCCGTGGTCTGGAGACGAAGCCTGCCCCTTCACCTGAAGGAGTCTCATCTGTAAAAT
GGGGACGATACTGTTTGGATAAGGCTGATGGACATTTGACAAGTGCCAGCTTACTCACACTGCCACGTGGGTCTCCATCTCAGTCACAAGCGACCTTGTTTTTTAAAGGGAGACTCTGAAGTACGGGT
GGAAATGGAGAAACAAGGGGAGCATGGATTTCACAAGTGCCTTCGGAGAAGACAGAATAAGTCACCGACCCTGATCCAGTGTCTGTCCAACATCTCAGATGTCAGCTGCTGTTACAATGATGGTATGC
CTGTTGAAGTCAAAGGGTCCTTCATTCAGTACGGTGAAGACCTGATACTAGAGGCACACTGCTTGCAGATATATAATACCACCCCGTGCCATCTGATATGGGGACAGACAGTCCACACTCATTGAATT
ACTGGAAAAATCAACTTTGCCTACATAGTTAGGAAGCTATTTGGAACCTCCAGTGTTTTTCTTTCTCTTAAACAAATAATGAAGCAAGCTTTGTATGGGGACCACACCTGTAATGCCAGCAGTCAGCA
AAAAGACCACTGCAAGTTCAAGGCCAGCCAGTGCTTCGTATTGGGTTCAAGCTACACCTGTAGACTAGTGCTACTAGTGAGCAGACATCTGCCGTTTAGGGAGGTGATGCTCTTCTGACCCCCAAGCT
TCCTCCCTCGCTGTCTCTGCTCAGAACAAGCGTTTTCCCAGTAAAGCTCACCCATTGCCGAGAAGACGAGAGCTCACTGCAGGCATCTCTCCTACTTTAATGGCTGAGGCAGAGAAATCCATCATTAA
CTCAAGCTCTTCCCCTGGGGTCAGCATGCTATCGTGGAGGAAGGGCAGAGAGCAACGCAGACTCCTCATCCCAGTCTCTCCACCCACTGTGCTGTGCTATGCTGTGCTGTGCTGTTCTGTGCACCCGT
GAAACGGCTATCAGAGTCAACAGCACAGCTAGTGTCTGGCAGCTGGCTTCGTCTAGTGGCTGATGGGAGGAGTTTCCTTTCAAGACCTCTGCTGCTCTAGAGGACAGGCCCTTTCCTCCTAAGTAAAA
GGAAAATGCCAGGTAGATTCTTATTTTCCCTTTGTGGGTTTACCTGCCAAGGTCATAGGAGACTCTACAGGTGAGAGGAGTGGAGAGCAAAATTCCTCCTGACTGTTGAGTAGAAGTCACAACAAGCC
TACTGTGTGCCTGGTGGTTTCTTTGGCAGGTGGAGGAGAGAGCATAGTGATGGCTAAGCAGTGGGGCCCTGGGGCACTTGGTCTAATGAGGTGAGAGGCATGAGAGGTAAATAATAAAACAGCTCTAA
ACCAGTGCTCCCGACAGTAGCACCCCCTCAACCCCCACTCCCACCAAGAGGGAGCCATGGGCGAGGGCCCGGGTGTAAGCTGTGCTGTCACATTCGGCCTTGCACCTGGTGTAATGCTCTTTTGTGAT
CTTGAAATTCTTATTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGGGGCTGAAACTCTTGAGTGTAAAACAGGATAGGTTACCAGTCTGCTGAGGGCAGCTGAGGCC
ATCACGCTGCAACACTGGGAGGATACCAACCATTAGCAATTCATTGACAGCCTTGCAGAGATAGTCTGTTTCGGCTAGCTGGGGCTGGGGTGGGTGAGGTTTTGCCTGAGCTAGAGATCTTGTAGGAC
TACGGGGCTGCTGGAGAGGAGTCCTGAGCCAGGGGCAGTGAGGCAGATATGCAGGAGTGAGGCAAGGCCCTCTGTGGAGCCACGGAGCGCAGCCGCTCAGCTGCAGCGGACGACCTGCGGATCAAGGT
TCTTGTCAGCGTCGAGAGCGAGCGTCACTAGAACAAATATTCATCCAAAAATAAACTTCCTGCTCTTCCTGTTTTTATAACTTGCCTATTTCCTCTGAGTTTGAGGCTGGTCTCCTGTTCCGTGGGTG
TTAATCTTCAGAGGATCAAGACCTCTATAGAAGCATTTCCTGTACATGTTTATCCACCCAGCCTGAAATTATTTTCTCCAAATGATAAGAGAATTTTTTTCCATCCTGGTATGTCAGCCTTTGAAAGG
TTTTCAGTTGGGAATCCCAGGGATGAAGGCTCCAGCCAAGTCATAGGAGACCCAGACAGTGACAGCTATATTGTGCGTGTCAAGGCTGTGGTTATGACCAGAGATGACTCCAGCGGGGGATGGTTCCC
ACAGGAAGGAGGCGGGATCAGTCGCGTCGGCGTGTGTAAGGTCATGCACCCTGAAGGCAACGGACGAAGCGGCTTTCTCATCCATGGCGAGCGACAGAAAGACAAACTGGTGGTATTGGAATGCTATG
TCAGAAAGGACTTGGTCTACACCAAAGCCAATCCGACGTTTCATCATTGGAAGGTTGATAACAGGAAGTTTGGACTTACTTTCCAAAGTCCTGCAGATGCACGAGCCTTTGACAGGGGCGTGAGAAAA
GCCATTGAAGACCTTATAGAAGGTTCAACGACCTCCTCTTCCACTCTCCATAACGAAGCTGAGCTCGGAGACGATGACGTTTTCACGACAGCTACGGACAGTTCTTCTAATTCCTCGCAGAAGAGGGA
GCCGACTACGAGGACAATCTCCTCCCCCACGTCCTGTGAGCACCGGAAGATTTATACCCTTGACCCATACCCCATGGACCATTACCACCCTGACCAGCGGTTGCCGCGGTCCTACCCCCAGGTCACCT
TCCCAGAAGATGATGAAGAAATTGTACGCATCAACCCCCGAGAGAAGATCTGGATGACCGGTTATGAAGACTACCGGCACGCGCCGGTTCGCGGCAAATACTTAGACACCACAGAAGACGCGGACTCC
TACGTGCGCTTCGCCAAGGGCGAAGTCCCCAAACACGAATATACCTATCCCTATGTTGATTCTTCGGACTTCGGCTTCGGGGAGGATCCCAAAGGTAGTGTGATCAAGACACAGCCGCCCAGGGCCAA
GTCCCGTCGGCGGAAGGAGAACGGCGAACGGTCGCGGTGTGTGTACTGCAGGGATATGTTTAATCACGAAGAGAACCGAAGGGGCCACTGCCAAGACGCGCCCGACGCCGTGAGAACTTGCATTCGCC
GGGTGAGCTGTATGTGGTGCGCGGACAGCATGCTGTACCACTGTATGTCCGACCCCGAGGGAGACTACACTGACCCTTGTTCGTGTGACACAAGCGATGAGAAGTTTTGCCTCCGGTGGATGGCTCTA
ATTGCCTTGTCTTTCCTGGCCCCTTGTATGTGCTGTTACCTGCCCCTCCGGGCCTGCCACCGCTGTGGAGTGATGTGCAGGTGCTGTGGTGGGAAGCACAAAGCCGCCGCGTGACTCGGTTCCCCTAC
TTTCTGCTTCTCCATCCACGGCCACGGGCAACTTGTCTCTTGCGCACTCCCCCATCCTCTCCCTGGTTCCCTTCCAACTCCAAAAGGCTAGGCCAATAAGAGGAGGCCAGGCTCTGTGGTCCCTTGGT
GACATCATTCCAAACCTGGGGTAGCTGCCGCCCCCTGTGTCAGCCACATACCCCCTCTCGCAGTGTTCTGAGGAAAGGAGCCTTCGGCATAGACTCGTGTATTTTACCAGCCTATAATCGTGCTGAGT
GTTGGTTTCCTGCCCCTCCTTCCCACCTTTCTGGTTCTGCAGACTTGGAGGGGTTTATTGACTCTCCCCCCCCCTCCCCCGCTCTGTGACTTTTTTTTTTTTCTTCTCCCCATTGGGTTTGCCTGTCG
CTAACTAGCATAGGTCCCACAGAGATGTGACAGAATGATGAAGCCGGCACCACAGCATGTTGTTATGTGAGGAGGCAATCTGGATAGCAAGCATGTACCACAAAACAGTAGTACTTTAACCCCTAATG
CCACGTCTCCCCATCAGCTGCCGGTTTTGTCTTTAACCTGCTATCATCTCTTCTCCTGCCCCTCCCTCCCCATGAATTAATTCACTAATGCAAAACAATCACTTTTTAAATGACTTTTTGAGCCTTAA
ATCCATATTCACTTGTGAGAATCAGGAAAGAATTCCTCGAGTTGCTTTGCATCCTCTTGGACCAGGGCTTGCAAGGCGATTTGGGTTTCTGTGAGCTTGCCCAGTTGACCCGAAAAATAGGACTTTTT
AGAATTGCATTGCCACTTCTAAAATCCTAGCAATACTTAGAATAACACATCAGTGAGATAAATTTTACTCAATTATTTTACAAACCAAATTGAGTTATTCAAACACAAGCCAGTATTCTGTGAACAAG
TTCCAGATGAAAAACACAGAAGTTGTGAATGAAGTTGTAGCCATTCCCTGCCCTGCACTATATTTTTCAGGGTGCATTTTAAATACTATTGATTCAAACAGTGGTGGCTTGCGTTTTTTTAGGTATAT
ATTTTTGGTTAGTTTTTTGGGGGGGGTTGTTTTGTTTTTTTAATTTGAGGCTCAATTCTTCATTTATACTTGAAAAAAACAAGGCCATATGTAAAGAAAAAAAAAAACCCTCTTTCAATGCCTAAGTG
TCTTCTTCTATCACTCCACACCCACAGTTGCCACTTGGGGTGCACAGATAAGGGTAGGTCACCAACTGATTATGCCTGTCTCTGAGCCATGCAAGAGGCTCCTAATGTGCTGGGGGGGGGAGCACATA
TGCATATATATATATGAGAATAGCCAACTTCTACAGAAAAAAGACAAGTGGAAGTGGTTTACCAATACCTAGCATGGTACAATCAGAGCTCCGTGGGGACTGTAGGGAGCAGGGTGTTACTACTGGCC
GTTCTTCCCACAGTGATTAACGGTAGAGATCAAGCTCAGTCCCCTTTATCCCCCCCCCCCCCCAAGCTCAGTCCCCTTTAGTCCTTCTTCCCCTCCCCCCTCCCCCATTGCACACAGACATCCGTCTT
TAAAGGAAAAGGCCTTTTTTCCAGTCAATCAGTCAGTCAGTCAGTCAGTCAGTCATACTGGGAGAAGCTAGCCTTGCATCCCTAGCACTGTCTCTTCCTGGCAGTGCTTTCTGCTCGCCCGACAGACA
GCCTGTCGTGTCTCTTTGGACAGACGGACCATCAGTGTAGATAATCAGCATGCTTGTGCATTACGTGGAGGTTGGAGGTGTCATCTTTGTTGGGATGACTGATTGGGGCTATCTGTTGTCAACAAGCG
TCGTCTCCACCATTGTGGATGGAGGGGGTCTCTGTGCTAGGAGACTCTATAGACTGCCTCCAGCCGCCCTCCAGTGCTGTGGAGAGACTGTCCCCAGCCTGAGGGACTCTCCTCGGGCCCTCGCCTCT
CTACCAAGCACAACACTAATCCTGTTTCCTTAAACCTCCGTTCAAGTGCCCCTATTTATTTCAGTGAGAATGCGTGTCCGGTTGCCTCTGTCCCTGTTTGTGCGTCCTTCCTCCCAGCCGGTTCCCAC
CCTCCTAAGGGTTATGCCAGTGGATCTCACGCCTCTGTGCATCACCTATCTTTGGTTTGTGAAGGCAGCAGTTAAGGGCACAAAGACAGCCATGGGGACATTTATGTAAATATGTTTAATTGCCACAC
TGCAGCTGAACGGTGTGTAGTATTTTCCCAGTCAGCTTTGCCATACTGACGTCAATCATTTGAGAGAAATTATTCAGATTTTATTTTTATATCCATGGTAACAGAACCTAACCAAAAGGTTTCCCGTT
CAGAAGTTTCCTTAGCTCTCGTCCCAAGCTATTCGCTCACATTAACAAGTCAAAGTGCCTGAAGCATAACTCATTTACCTGTATACTAAAACCCCTGTTGTACTGATTTTTTTTTATAATAAGCCTTT
TTACCTCTGTAAAAATATATATATATACAAGTGTATGATGTACATTTTAGTTCTTAACTTTTTTATGGTTTCTAATATGTATGACCAATGTAGCCATTGCTTTGAAATGTAAATATAAACACGTCCTA
TCCGA

hide sequence

RefSeq Acc Id:

XM_006514457 ⟹ XP_006514520

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	19,941,347 - 19,974,026 (+)	NCBI
GRCm38	11	19,991,335 - 20,024,026 (+)	NCBI

Sequence:

show sequence

AGAAGATAAAAGCGGTCAGCTCTGTGTTAGGACCCCTTGGGTGGTAAGTCAGAAGCTCTGCGTG
GCACAGTTACCAGCAGGGGTTTAGAGACGTAGGGATGGGCATGGTGAAGTAGGCACGGAGCCTGCTGTTTCTCAGAATGGCTCTGTGCCTGGGCACCGAGTTCCAGCTGACGGATTGGGCCTGTTCAA
ATACACAGACCTTTTACTCCCAGATACTGGGGACGGGCAATTTCATAGGTGGCTCCTGGGTTCCTTTTTGTGATTGGCCTCACTGGTCAGAAATATCTCCAGGCCAGCGTTTTTCTGAAGTGATTTTA
GCCCACTTTTCAGCTTCCCTTACCGACATTAGGGACATAGTTTCTCTTATGACGCAAAGGATTAATGTTGACAAAGGGACCCAAATGTTTCACATCAGTGCCTGAGAGGAGAGTTGACTGCCCTCCCA
GACAGGCCCCATGCCAGAAATGGCGTCTTTGCAACTAAATCTTCTATCCAACAGGAGGTTTTTCTTAAAACTGTTTTCCATAATGAGCTACTAACCAGACATGTAGTAACCACTTAAGTAATGGAGCT
AGAGGCCTTATTTCCTATGCATATAAGCGTGCAGAGCAAATGTTTTCTCCCTTGGATGCCTTGTACAGAGCAAAATACCCTGTAACTACCATTCAGAAAACCACATGGATAACTTTTCTAGCCCATCG
AGTTTGATTTATGATTATGAAAATCAAATATATGATTTATTTTTAAACCAGGGCGGTCATTTTTTTTATGACATTTTAGGTAATTGACACTTAGGAACACTTGAAAAAGCGACAGGAGTGGACTGTGA
CCAGCGCCTTCGGCTTCTCACCGTGTTTGACTTTGCCATAGCGTCTCGATGATTGGTTTTACAGAGCTCACTAGTGACAGCTATATTGTGCGTGTCAAGGCTGTGGTTATGACCAGAGATGACTCCAG
CGGGGGATGGTTCCCACAGGAAGGAGGCGGGATCAGTCGCGTCGGCGTGTGTAAGGTCATGCACCCTGAAGGCAACGGACGAAGCGGCTTTCTCATCCATGGCGAGCGACAGAAAGACAAACTGGTGG
TATTGGAATGCTATGTCAGAAAGGACTTGGTCTACACCAAAGCCAATCCGACGTTTCATCATTGGAAGGTTGATAACAGGAAGTTTGGACTTACTTTCCAAAGTCCTGCAGATGCACGAGCCTTTGAC
AGGGGCGTGAGAAAAGCCATTGAAGACCTTATAGAAGGTTCAACGACCTCCTCTTCCACTCTCCATAACGAAGCTGAGCTCGGAGACGATGACGTTTTCACGACAGCTACGGACAGTTCTTCTAATTC
CTCGCAGAAGAGGGAGCCGACTACGAGGACAATCTCCTCCCCCACGTCCTGTGAGCACCGGAAGATTTATACCCTTGACCCATACCCCATGGACCATTACCACCCTGACCAGCGGTTGCCGCGGTCCT
ACCCCCAGGTCACCTTCCCAGAAGATGATGAAGAAATTGTACGCATCAACCCCCGAGAGAAGATCTGGATGACCGGTTATGAAGACTACCGGCACGCGCCGGTTCGCGGCAAATACTTAGACACCACA
GAAGACGCGGACTCCTACGTGCGCTTCGCCAAGGGCGAAGTCCCCAAACACGAATATACCTATCCCTATGTTGATTCTTCGGACTTCGGCTTCGGGGAGGATCCCAAAGGTAGTGTGATCAAGACACA
GCCGCCCAGGGCCAAGTCCCGTCGGCGGAAGGAGAACGGCGAACGGTCGCGGTGTGTGTACTGCAGGGATATGTTTAATCACGAAGAGAACCGAAGGGGCCACTGCCAAGACGCGCCCGACGCCGTGA
GAACTTGCATTCGCCGGGTGAGCTGTATGTGGTGCGCGGACAGCATGCTGTACCACTGTATGTCCGACCCCGAGGGAGACTACACTGACCCTTGTTCGTGTGACACAAGCGATGAGAAGTTTTGCCTC
CGGTGGATGGCTCTAATTGCCTTGTCTTTCCTGGCCCCTTGTATGTGCTGTTACCTGCCCCTCCGGGCCTGCCACCGCTGTGGAGTGATGTGCAGGTGCTGTGGTGGGAAGCACAAAGCCGCCGCGTG
ACTCGGTTCCCCTACTTTCTGCTTCTCCATCCACGGCCACGGGCAACTTGTCTCTTGCGCACTCCCCCATCCTCTCCCTGGTTCCCTTCCAACTCCAAAAGGCTAGGCCAATAAGAGGAGGCCAGGCT
CTGTGGTCCCTTGGTGACATCATTCCAAACCTGGGGTAGCTGCCGCCCCCTGTGTCAGCCACATACCCCCTCTCGCAGTGTTCTGAGGAAAGGAGCCTTCGGCATAGACTCGTGTATTTTACCAGCCT
ATAATCGTGCTGAGTGTTGGTTTCCTGCCCCTCCTTCCCACCTTTCTGGTTCTGCAGACTTGGAGGGGTTTATTGACTCTCCCCCCCCCTCCCCCGCTCTGTGACTTTTTTTTTTTTCTTCTCCCCAT
TGGGTTTGCCTGTCGCTAACTAGCATAGGTCCCACAGAGATGTGACAGAATGATGAAGCCGGCACCACAGCATGTTGTTATGTGAGGAGGCAATCTGGATAGCAAGCATGTACCACAAAACAGTAGTA
CTTTAACCCCTAATGCCACGTCTCCCCATCAGCTGCCGGTTTTGTCTTTAACCTGCTATCATCTCTTCTCCTGCCCCTCCCTCCCCATGAATTAATTCACTAATGCAAAACAATCACTTTTTAAATGA
CTTTTTGAGCCTTAAATCCATATTCACTTGTGAGAATCAGGAAAGAATTCCTCGAGTTGCTTTGCATCCTCTTGGACCAGGGCTTGCAAGGCGATTTGGGTTTCTGTGAGCTTGCCCAGTTGACCCGA
AAAATAGGACTTTTTAGAATTGCATTGCCACTTCTAAAATCCTAGCAATACTTAGAATAACACATCAGTGAGATAAATTTTACTCAATTATTTTACAAACCAAATTGAGTTATTCAAACACAAGCCAG
TATTCTGTGAACAAGTTCCAGATGAAAAACACAGAAGTTGTGAATGAAGTTGTAGCCATTCCCTGCCCTGCACTATATTTTTCAGGGTGCATTTTAAATACTATTGATTCAAACAGTGGTGGCTTGCG
TTTTTTTAGGTATATATTTTTGGTTAGTTTTTTGGGGGGGGTTGTTTTGTTTTTTTAATTTGAGGCTCAATTCTTCATTTATACTTGAAAAAAACAAGGCCATATGTAAAGAAAAAAAAAAACCCTCT
TTCAATGCCTAAGTGTCTTCTTCTATCACTCCACACCCACAGTTGCCACTTGGGGTGCACAGATAAGGGTAGGTCACCAACTGATTATGCCTGTCTCTGAGCCATGCAAGAGGCTCCTAATGTGCTGG
GGGGGGGAGCACATATGCATATATATATATGAGAATAGCCAACTTCTACAGAAAAAAGACAAGTGGAAGTGGTTTACCAATACCTAGCATGGTACAATCAGAGCTCCGTGGGGACTGTAGGGAGCAGG
GTGTTACTACTGGCCGTTCTTCCCACAGTGATTAACGGTAGAGATCAAGCTCAGTCCCCTTTATCCCCCCCCCCCCCCAAGCTCAGTCCCCTTTAGTCCTTCTTCCCCTCCCCCCTCCCCCATTGCAC
ACAGACATCCGTCTTTAAAGGAAAAGGCCTTTTTTCCAGTCAATCAGTCAGTCAGTCAGTCAGTCAGTCATACTGGGAGAAGCTAGCCTTGCATCCCTAGCACTGTCTCTTCCTGGCAGTGCTTTCTG
CTCGCCCGACAGACAGCCTGTCGTGTCTCTTTGGACAGACGGACCATCAGTGTAGATAATCAGCATGCTTGTGCATTACGTGGAGGTTGGAGGTGTCATCTTTGTTGGGATGACTGATTGGGGCTATC
TGTTGTCAACAAGCGTCGTCTCCACCATTGTGGATGGAGGGGGTCTCTGTGCTAGGAGACTCTATAGACTGCCTCCAGCCGCCCTCCAGTGCTGTGGAGAGACTGTCCCCAGCCTGAGGGACTCTCCT
CGGGCCCTCGCCTCTCTACCAAGCACAACACTAATCCTGTTTCCTTAAACCTCCGTTCAAGTGCCCCTATTTATTTCAGTGAGAATGCGTGTCCGGTTGCCTCTGTCCCTGTTTGTGCGTCCTTCCTC
CCAGCCGGTTCCCACCCTCCTAAGGGTTATGCCAGTGGATCTCACGCCTCTGTGCATCACCTATCTTTGGTTTGTGAAGGCAGCAGTTAAGGGCACAAAGACAGCCATGGGGACATTTATGTAAATAT
GTTTAATTGCCACACTGCAGCTGAACGGTGTGTAGTATTTTCCCAGTCAGCTTTGCCATACTGACGTCAATCATTTGAGAGAAATTATTCAGATTTTATTTTTATATCCATGGTAACAGAACCTAACC
AAAAGGTTTCCCGTTCAGAAGTTTCCTTAGCTCTCGTCCCAAGCTATTCGCTCACATTAACAAGTCAAAGTGCCTGAAGCATAACTCATTTACCTGTATACTAAAACCCCTGTTGTACTGATTTTTTT
TTATAATAAGCCTTTTTACCTCTGTAAAAATATATATATATACAAGTGTATGATGTACATTTTAGTTCTTAACTTTTTTATGGTTTCTAATATGTATGACCAATGTAGCCATTGCTTTGAAATGTAAA
TATAAACACGTCCTATCCGA

hide sequence

RefSeq Acc Id:

XM_006514458 ⟹ XP_006514521

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	19,914,233 - 19,974,026 (+)	NCBI
GRCm38	11	19,968,235 - 20,024,026 (+)	NCBI

Sequence:

show sequence

GGGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTATAAGTATGCACATA
GAAGTCAGAGGAAAAGTGAAGAGTTGGGGATGAGGGGACGGGACAAATAGCCTTAGTGTTTTTAACTCCTTGGCCCTGGAACACCTACCCCTGAGAGTCTCCCTTGCTTTTTATGCTTAGAAATCCCA
AGCCAGCATTCCAGTGAGTACTTTAAAATACAAATTTCCTTGACTGAGTCTGACAGACAGAGGCTGAGGTGACCTGACTGGTGCCACAGTGGAACCTGGAGGGAGGCCAGCTGCCTTTCTTTGAGGCC
TTAGGTGGGCCTGGGGCAGCCACATTTTCTAAACGCTACCGCCACGTGCCACCACCTCTCCTATCAGAGACCCAGGTGACACCATTGGGAGTGACTGCCCCCAGACCACTGACCAAGTCTGTGGCCAC
TAGTCATTTGGGTTCTGAGCCCTTAAAACAAGCCATCGTGGGCTGAGAGGTGGTGTGATTTCATTACCTTATTACAATACATGCTAGACACCCTACTAGTAATTATTTTGATTGCTGTGGGAACAAAA
CTATTTTAGATATATTGAGTTATGACAACTCTAAGGAAAAAAATTCAAATTGTGGATATGGCTTGTTCCATTTCTGTGTGGTGTGGTGCATTCACAGGTACACAGTCTCTGGGCTGTCTCCCTATTGG
CCTAGCTGAGTGGTGACCTATCCCTAAACCTAGACTTTCCTAGGACAGTGGTTGGGACAGCGATTCCTGTAGGCTGACAGTTAATTCTCACACACATACACACACACACACACACACACACACGCACA
CGCACAGAGTTGTTTTGGTTTTCCTTTGTCAGCCTTGCTGATCAGTCTCCTTCCTGGAAACCTTTTTTCAGAGCCTACGGTCTTCCTGCGCTCCTGCCCCCGGGTCAGACTCTACGGCTGGTTACCTT
TGATCCGTTCACTGCAGGCTGGTTGTCTAGAAACTCAGTGCTCAGTTGAACCCTGAAACCACTGTTGCAGAGCAAATTGTGTGTGGTGGGTCCCCAGTCCTTTTGTGTCCCATTGTATGTTATTCCTG
GTCCCCATCCTACTCCACCCCACCCTCATCTGCCCATACGTGCCGGCGCGCCTTTGGAGTGAATGAGCATGCGCTGGGGAAACACAGGGTAGACGTGAGGCCTGGGAAACTCCTGCTGTGGGAAGTAC
AGAAGTCCCTTCGCTGGGCTCACCCTCCTCAGTCTGCCGGCATTTCTGGAACAAGGGGAAGTTCAGCTGCTGGCTGAAGCCCCAGATAATTCCCTGCTGCAAATGAAGAGCTCCATATTGACCCAGAG
TCCAGGAGAACGTGTTTACAGGGCAAACCCTGTTCTGCTGACCCGTACAGTACCCCTGTACCAACTACATTTTTGCCCCCACTTTGTGGTCTGTTTTATATTTAACCTTTTTTTTTTTAAATCTCAGC
TAGATGGGAGCAGGCATGTGTTGAATGATTGGGGTATACAAGCATGGCACAAAGTTAATTAACAGAACAAACGCCAAGATACCCAAGTAGCCACTGTTATTTCCCTGTTTGTAGACAAAGCACCTACC
CGCAAATGAGTTTCCCCACAATGAAGCAGGATGTGGGCACACAGTGTAGGGCTAACTCGAGTCCTGTATTTGAGCAAATCAAAGGTTGTACCTTCAGGTTCACTAGGGAAGGTAGAGTGGTCAAGCAA
CCTTTGGGTTCTTTCCTGTGAGTGGAAAGAGGTGCCATGTTCAGACCTTCCTGAAGGTTGGGTCTAAGGATTGGGCACATGGCTTTGGCGTTTGGTTGGATCTGGTTCAACCATTGTATTGATTCAGT
CATAGTAAACTAACCCAAGGTTGCCTGGGCCTCACTCCTCTCTGTGAAAGGGGGACATTCGTCCACGTTCTGTGTTGTTTTCTGTGTTGTTGTAAAAGTTTTGTCTATATTAACATAGAAAGTACCTC
AACAGACACATCTCTCCAAAGCCCCGAGGACGACACTAGATGTAACCACAAGAAAGTGGGCAGAGGCTCACAGCTGTCCATCAAAATATGATACCCACAGGAGCTCACAGTCCCTTGTGTTGTGAAGC
TTGTTGACCCAAGGGAATTGCTTGCTCCTCTCTACCTGAATAAGGCCAGCTCTTAGGCTGCTATAGCTATTGGATGTTTATAGCCCTTCAGCCAGTTAAAACAGGACCTTATCTGTCCAGGCCTGGGC
TGATCTCCACCAGACACACTTTGACACTTAATGCGCATGTAAGCAGGAGGGGTGTGGAGCCAGTGGAATGTGGATCTAGAGTAGGCCTGACTTCTGGCTTTATTCAGTCCACCAACTCCCTAGTTTGT
ACTGAGCTCTAGTGTTTATCCCTCCTGGCCTCAGTAATTCAAAGGAGCTGGCCCAGATCTCAGTCCCGGGGTCCTGGCCTCAGGAAGCCAGTGTCCAGCCACCAATGTCCTTTCAACATGCCCCCACT
TCTTACTGAGTCCCAACAGGTTCTCACAGCACTGATACCTAACTACCGCAGTACATCGGCATTACCCAGGAGCTTTGAAAAGGCAGGGAGCCAGGCTGTACCCCAAACTATATACCACCTAAAAAAAA
AACAAAACAAAACAAAAAAAACAACAGAAGCCTGCCATGCCACCACCATGTGTAGCTGAGACTAAGAACTAGCAGCTTTGTTGGTGGGAGAAAAAAGTTTAGTTGCTGAGGAAAGTGAATATGTGGTC
TTGGGAGCATATAGCCATTTTAAAGTGCAGATGTCATATGTAAATACTTCTGTGTGTATCCCTAAGACCTAGGGTAAGAGCCGCTGTACCATCAATCCAAATAACAAATCCGTTCCGTTTCCTCCAGT
TGGACTAAAGATACCTTTACAATATTGGGGTTTTTTTTTCTAACTAGAACCCCAGAAATATAACTAATTTCAATCATTTGACTTTGACTCTGGGGTCAGGGCATTGTAGTGATGCACATGTAGGTGAT
AATGGGTGTGCATTTCTGGAAAGTGGTGTCGTCTAAGGCACCTGGCCTGACTGATGCTTACAGGATGGTTCCCTGCCTTCCTGAGTCCTTCTGGAGGCAACCTCCCTAATGCTGCCACCCTTTAATAT
AGTTCCTCATGTTGTGATGACCCCCCCCCCAACCATAAAATGATTTTTGTTGCTGCTTCATAATTGCCATTTTGCTACAGTTATGAATTTTAATGTAAATATCTGATATGTAGAATGCCTGCTATGTG
AAGCCTGTAAAAGAGTCTTTTGACCACCAAAGGGCTAGTAACCCACAGGTTGAGAACCACAGTTCTAGAGGAAAGCCTCATCTAGGCCCCAGATGTAGCATATATGCAGTGCTTAGGCCTGAAGGCAG
GCTTCTTTTGTAAATTCCAGATGCTATAAGGATGCCAGAGTTTTGAAAAGACTGGGTTTCGAATGGGGATGTATATGTAGCTCAAAGAGAGAGTGTTTGCCTAAAATACAGGGATTTCTAGGTTCCTT
TGATCCACAGCATTCCACAAACCAGGCATAATGGTGTACCCCTGTAGTCCCAGCATTTGGGAGGTAGAGACGGGAGAATCAGAAAAAGCTCAAGGCCAGCCTGAACCACACACACACAAAAGACAGTG
GGGTCCATTCTGTATACAGTTTCCATGTTCTTTGCTGGAAGCTGTAGCTAACTAAGAAGGGATGGTCTCCTGGGCTCTAAGGAGTTCTCCTTTGAAAGTTCCCCAGGCACTGGCTGACACTTGTGCTC
CTGTGGAGGGGAAGTCCAGCCTGGCTCCCCGGCAGTGGCCCTTGTGTTGACCTCCAACTATGTCTCTGGCTTCTGGTGGATGCTATGATGGACGATGGCACCAGACCGGTTGCAGTCTTTCTTTGTAA
AGTTTACTTGTTTCGTTGTTCATTGCTGTGAGTCAGGGTCTTCCTGTGTAACCTAGACTCAGGAAGCTCCACACCAGGTGCTGAGGTACTGGTCTGTTTTTTTTTTTTTTTTTAAAGATTTATTTATT
TATTTATTTATTTATTTATTTATTTATTTATTTATTTATTTATTATATGTAAGTACATTGTAGCTGTCTTCAGACACTCAGAAGAGGGGGTCAGATCTTGTTACGGATGGTTGTGAGCCACCATGTGG
TTGCTGGGATTTGAACTCTGGACCTTCGGAAGAGCAGTCGGGTGCTCTAACCCACTGAGCCATCTCACCAGCCCGGTACTGGTCTGTTTCCTCACCACATCCAGACAGAACTTTTTAAAGTGACAGAT
ATCAGGATAGCTCCCGATTGGATGGAGAGGTGGGGAGGGTAGTCAGCAGGAAGAGGGTACACATGGGGATGGAGGACAGACACCCCGCAATTGAACCCTCATTCCTTCCTCAAAAGTTCTGTTGAGCA
TCTTTGACACACTTTATAGCCCAGCAAATCAGACTTTCCCCAAGGGCTCTGTCTTGGGTCAGGATGGGTTTGCAGCTGCTGAGGTTTTTTTTTTCTTTCTCTTTCTGTATCACAGTCAGGTGGTTAAC
AGCAGTAAGCACACATCTTGGTATTTAAAGACATCTCTAATGTTATTCATCGCATGACTGATCTTGCAAAAAGGTTAGGAGGACGCAAATGCTCTTTGCTAATGTGGGAATGGGGTTGTAGCTCATAG
GCAGTTCATTTGACCCTGCGTAGGCTCTGGGTCTCATGTGTCTAGCTCCACAAAGACAAATAGTCGCTAAACAAAATCATGGTGTGTCCTTATCGTAGTGGGCAGATGTGAAAAAATTGGCTGGGTGG
TTTGTGTTCTAGTTTAGAAAGACCAAAGGGATAAAAATCAAGGTCCAGGAGCTAGAGAGGTGGCTCAGAGCTTAAGAGCATCATCGGCTTGTTCCAGGCGACCCAGGTTCAATTGCTAGCACATGAGT
GGTAGGTCACAACCATCTGTGATTTTAGTTCCAGGAGACCCAATAACTTCTTTTGACCTCCTCACATGGTGCAAAGATATGCCAATGCACATAAAACAATCAACTTCTTAAAGTCAAGGTCCGAAGAC
TATGAAAGGTATGCTTTCTGTGTTTGTGCGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCGTGCGTGTGTGGTTCACAAGCCCTCCCCTTTCCACTTCAGTGCTGGGACCACAGGCATGTGCCACCACA
CCTGGGCTTGTGTCACCCTGGGGAAGATTGTTCCCATGGCTTCTTGCTTGCTGCTCAGGTGTTCTACCAACTAAGCTATATCTCAGCCTACCAAAAAACATGTAAGATGGCTCCTGTAGTCTTGATGG
TGAGAGAAGGGATACGATTATAGACTGTGATAGCATACACCTTCTTAAACGTTGACTTATGAATTGGAGAGCAATCAGCTAAAACAATCCATCTGTGTTTATGTTGCCAGATAAATTGGTGGCTTTAT
TATGTCCCAGTTAATCTGTGTTATAAGTTCTGACTGTTGCTTGTTAAAACACCTTAGGAATCTGCCCTCCTGTGACCCCAGCAAGGCTATGATCAGGATCAGCCAATGGAATGTGACTCCTGTTCTTC
CCATAATGCCCGCCCCGGCCACAGATGATAAATTTCTGTCTGAAGCCCTGGAACATTTCCCTTCCTCACCCTGAAGCACAAATGGGGCCAAGAGCATCTGGACGTTAACGCTAGGGGACAGGGAAGGC
ACAGAGCTGAGCCCTGCAGTGTGGCTAGCTGAGGTTTTCAGGGGGCTGTGGCCTTTGCATGGGGACTGTCTGGCTGCTTATCTGGTTGGCATTCTGTCCACCAAATTGATAGTATGTTTGTGTTTGTT
TCCAGCTTCTGAGTGGCAGGAAAATGGGACCCGGCCTGGTAGTTTGGAATGTTCAAATGTTGAGACTTGTCCTTCACACTGGGTTCATTCCTAAAGGCAGGGCTCACAGGAAGCAAACAGATGAAATC
TGGGGAAGCGTTCCTCCCTCCCGAGCTGAGAAAGAAGAGCAGAGAGGAGCCTGGGGCATTAGAAACAAGAACCTTGGTCAGAAGTTTTCTGGAAGACAAACTCAAGTACACACAGCCCAGGCCCAAGA
GCATATCTTGTAATGTCTCCATTCATGCTCTATCTTCCTAATCCTAGCTGGAGTGGGTGGCGTCCACATTAGTTCTCCATTCTCCCTTTCTTGCTTAGTACCTGATATTTTTGTGGAAGCGGGTGAGC
TGCCTCTCCACCATAACCCCTTAAATAAGTGCCGCACCAGGTTCGTTCTGATTGCACACTGACCAGTTTTCTCAGCAACATCAGCCTCTTTTGTACAGAGTTGGACATGGGGTGGAACTCACCCTTGC
TGGTGGCTCTTGAAGCCTGGTGGCAACAACTGAATACAATCCAAATAGGCCACACTCTGTCACATGTATGCAGTGCTGGGACAGGCCAGTACAGATGCGCAGCACGCTGACATTTAGGAGCTGTGCTG
GATGAGCTTGCACTGTGCCTTTCTGTACAAAGTCAAGGTCACGTGAGCAGGTGTGGAAGACACTGGCATTTGACTATCTTCAGTCTCTTGTTCTCTTCTGAGTGTGTTGAATTTGCAAGTTGTGTGTG
AGGCCCATCTTGACTGCCACACTGAACTCCCTCGCTCCCCTTCTCTTTATTCTTGTACTGGAAATCCATAGACCCTCACAAGAGCCATCCCAGCCGTCTACCACTGAGCTTCATCTCCATCCCCAACA
AGGTTCTTTGTTTCTTACTTGTTTATAGGTAGGGAGCAAGGGTGAGCACATGTGGAGGTCAGAAGACACCTTTCAGGGAATTACTTTTCTTCCATTATATGTATGGGCCAGGTGGTTGGCTTGATTGA
CAGCAAAGGCCTGTACCTTGTGAGCCATTGTTTTGGTTCTTAAGGGGATGGATAGGGTTTGAACTCAGAGATCTGTGTACTTGCCTCTGCCTCTTGAGTACTGGCATTAAAGGCATGAACTACCACCT
TACACCAGCCTATTTGTGTTTTTAAATAAACAGGCTCTCTAGTACAGGATGGTGGGAAACTCACTCTATTATCCAGGCTGCCTTCAAATTGGAAGCATTCCTCCGCAGCCTGGGGCTTGAAGGTGTGC
ACCACCTAATTTAAGATTATTGACTATTGGTTTTTTGTAAAGTTGGAACACAACTCTCACATGTATTGTGTGCCACCCCCACCCCCCATTCTCCAGTTGTTGTTGTTCTCCTCCTTCTTCTTCCTCCT
CTGTCTCTGTCTCTGTCTCTCTCTCTCTCTCTCTCTCTCTGTCGCTCTCTCCTGTCAGTCTGTCTTCCTTACCTATACTCATATTACACATAGCTGATGCCAAAGCCCAGCCTGACCACTGCTCATAA
GATGAACTTTCAGGCCTTTTAATCCCGTGAATTGTATGTTGCTTATACAGATAAATTATTAAGGTGCATTGCTGAGAATTCCCAGAAGAGACTGGCCGAATATCTGTCTAGCCATTTGACAAAGATGG
CTTCCTCATGGAAGGTTCATTCCATGAGGAGGTCACCGGAGTATTGGATAATGTTTTATGGTGACTGGTCTCAAATAGGGCAGTAGATTTTTCTCCAGAAGAGGGTTTTTTTTTTTTTTTTTTTTAAA
TTCATTTGTTTTGAGACAGGATGTCACCTTGTAGCCCTGGCTGGCCTGGAACTTGCTGTGTAGACCAGGCTGGCCTCAAATTCAGAGACCTGCCTGCTTCTGCCTCCCTAGTGCTGGGATTAAAGTGT
ACACCACCATAACTTCCCCCTCCTTTTCAAGGAGGGGACATGTGTAGGAGGAGTCAGAGGACAGCCTTGAGGAGTCATTTCTCTCCTTCCATTATGTGAATCCTGGGGATGAAACTCTGGTCACGAGA
CTTGGCAGCAAGCATCTTTATTCAGTGAACCATTTCACCAGCCCTGTTCCTGGACTTGCGCAACTCATGAGCAGCTTCAGGTGTCTTTATGGCTTAGAGTGAAGACACTGAGCGCCTATACCCATATT
ACACATAGCTAGTGACAGAGCCCAACCTGACCGCTGCTCATAAGATGAACTTTCAGGGCTGGTCTGATTAGAATGGCATTTGGTACAGCACCAGTTTGTGATCCCTGGTGCCTCTATATGCCTTTCCA
GGCTCTGAGCCTGCCCCACCCCTTTAACTTGATATTTCAGCCCTAGATACAGGTTTGGTTTGTCTTGAGTCCAGATCCCAGGAGGATTCAGGCTTGGCCCTGATTGGCCCTCTGCATGCCTACTCTAG
ACTTGAAGAGGAAGGAAATTGGTTCTCTCAGATATCTGACCCCCAAGCTGAGCCTAGAAGCAGCACTTTGAATACAGGCTTTTTTTCTTGCTAATTTAGCCCTTGGTTCCTCCTGTGGTTTTCCAGAG
TGACTTGTCAAAGCCCTTATGTATAGTGCTCTGTGCCACAGACCCTGTAGAGGGCATCAGTGCACCAAGGCAGCCCATGTCTGCTCCATGCCAACTAGGAACCAAATTTATAAACAAAATGCTATAAC
CCTATAGAGTGGACATGGGATAAATGTGGGTTCCCTTTGCCTTTTCCTAGGGACAGCTGGGACACAGTCCTGTCTCGCATCTGTGTCATAGGGTCTCATGAAAGGGAAACAAATACAACCGTTCAGCG
CAGTTAGCTCATATGCATCTGATCAGCACAGGCCTCAGATTGTGGCAAATCCAAACTCTGCGTGAGATGAACCACAGAGAGCCAGGTAGACAGAAGTCAGTACCACAGAATACTGAATTTGCCTGAAG
TTGTTCATCACAGTGCCAACATATCTGACTCTTCTCTCAGGAGGTAACCATATAAATCTATACCTCTAAGCTGCCATCCCTGCCCCTGGGCTGTCCTGGCTATTCTCTGTTGGATTCACTTTGTTGGG
AAAGCAGCACATGACCACCAGGAAGACAGCTATCCTCATATACCCCAGATTTCATCTGTGTCCTAGCAGCTGGCCAAGACTTTGTTTTCAAAAGAACATAAGTGAAGGCCAGAGAATGGTTTCTTTTG
TTCAGATTTCCCCTCTCAGAGACTCGTCCCAGGGGTCCCTTCACCTGCATTATCCATTAATCCTGAGGATTCATTTTCCCCCAAATAAACAAGTTTTCTTGCCAAGGAAAATTTGTATGGTAAGTGGA
TGCAGTGCTTTCTCGGGGCCATCTTCTGAGGCATGCTTTTCATCTCCCTGGGTTGGCACCCAGCTCTCTGTTATGGGCAACAGTGTTGTGCAGCCCAAGTTTCCTAAGGCCCTTGGCAGCTTTCACAT
GGCCACCCAGCCTCCTAGAAAGCAGCACCCACTCCTGTTCGCTCAGTTTCCTGAGGGCTCCTTTCCGATCATCTTTCACCTCTTGCTTCACGCTCCTGGGACACATGCAGTTTCTGTAAACTGCACAG
ATGTGCTGGGGGAGGGAGGCATGGCTGTGACCTTATACACTACATCTGATGGACTATAAACTCCAAAGTAGGGAGGGGACTCTCTGAGCAAGCAAGTCAGGGTGCAAGAGCAACGGGCTTTCGTTTCC
ACCCTGTGGGAAGACAGAGTGGGCTGTTCCCGTTGAACTCTATAGCTCATGAGTTGCACAGGACCATAGATAACATTTGAGTATCTGATTCTAGATTGGAATGTTAAGCAATAAGGGACCAATAAATG
ACAGACACTTTGGGGTGGGGAGTATGAGACAGTGTTTCTCTGTGTAGCCCAGGCTGTCCTGGAGCTTGCTCAGCAGACCAGGCTGTCCTACCTCTGGCTAAAGGCTTAAAGGCTTAAAGGTGTGCAAC
ACCACTGCTTGGTATTTTTTTTTTTTTTTGTATTTGTATGTTTTGCTGACAGACACAGGCGCGCACACACACAAAGGAGTCATCAGACTGGATCTTAGTGAGGGGGTCACTTAATCTGTCACAGCTGC
TCAACTCTTAAGTTTGCACCTCTGGAGCACAGAGGAGTGTGGTGGCTCAGCTGGCCCACCCCGGAGAGTGGAATTCACACACACTGTGAACATCCTCATCACTGTGTGTGTGTGAGCTGAAGAGCCAG
ATCCCGTGCTAAGCCCTAATGGAAGCGGGCACACTTACCCATTCAGTCCAGCACTGCATGAGGAAGTCAGGGTCAGCCGCTACTGCTTATTATGACAGGAGAAACCTGTTCTTGTTTTCTGATCCCTA
CTCTGAGTTTGTCCCCTAAGCACCTGGCTTGCTCCTATAACATTTTATGCAGGCAGTCTGTTAAACACTGGTTTTAATGTGCGGTAACTATTAGAATGGGCCATTGACAGCTATGCCCAAGTCCTCCC
CTCCCATGTGTTTTTTTCTATGTAGTTCTTTCCTTAATAATATATACATTTGAGCAAAATTTTGTTTCATATATTTGAGAACTACAGGATAAAGTGAACATTTTATGGAGTTTGTATTTTTCATACTC
AAGATGAAAATAAGGTTTGGGGCTGGAGAGATGGCTCAGCAGTTAAGAGCACTGACTGCTCTTCCAGAGGTCCTGAGTTCAAATCCCAGCACCCACATCGTGGCTCACAACCATCTGTAATGAGATCT
GACGCCCTCTTCTGGTGTGTCTGAAGACAGCTACAGTGTACTTACATATAATAAATAAATCTTGAAAGAAAATAAGATTTGGTTTTCTTTAGTTTTTGATTAGTCCATTCTCCCAGCCTCCACCTCTA
CCCCACCTCCCAGCCCCCTTGAGGCATTCCTGTAACCAGGCTGGCCAAGGCTGAGCTTCAACTCCTGATCCTCCTGCCCCAGCCTCCAGAGTGCTGGGATTAAGCATGTGGTACTACACTCAGCGAGG
AATTAAGTTTTAAATAAACATACCATTTTACCTGAGAAAGGATAGCTTTATGAGTTATCCATAATATAAACTCACTTTACAGTAAGGAGAAAGGTTTTGAGAAGACAACATAAGCCTGGGTTTTGAGC
CAAGACACCTGGGTTCTGAGTGCATTTTGTTTTTACCTTAGAGTATTTATTACAGTGCCTTGTTACCCATGATAACTTTCAGATCTTGACATTGGCTTGTATTTGTTTTTAAAAAACAGAATACAATA
TAACGACTTAGAAGAAGAAAAAACTTGACAAATTCAAACATGGCAAGAGCCTTAAACTAAGGCTTTGTGGGGCTGGAGAGTTGACGGCAGCCAAGAACATCTCGTGAAGGACCCAGGTTAAGTCCCAG
CACCAACATGGTGGCCCAGAGCCACTTGTAACTCCAGTTCCAAGGGATGTGATGACCTCCACTGGCACTGCACAGAGACAGGGCACAAACACTCAGCAGGCAGAGGCAGGAGGATCTTTGTAAGTTAA
GGCCAGCTTGGTCTACAGATTGAGGTATAGGATAGCCAAAGCTACACAGAAAAACCCTGTCTCAAAACAAACAATAAACAAACAAAAAGAAGTCTATTAGGAAAATCAAAGAAACCAGGGGCCAGGGG
CTGGAGAGATGGCTCAGCAGTTAAAAGCACTGGCTGCTCTTCCAGAGGATCCAGGTTCAATTCCCAACATCTCCATAGCAGTGCACAACTGTTTGTAACTCCTGTTCCAGGGGATCTGACACTCTCAC
TCAGATATACATGCAGTCAAAACACCAATGTGCATAGAATAAAAATAAATCTGAAAAGAAACCAGAGGCCAATTTGCTGTGTTTTTCCTGGCTGGTTTGACTTCCATGCTAGAAAATGAACATGTGAA
GGTATGGGAGCCCAGAGGCCAAAAATACCTACTGATCTCTGTGGTCCCAGATCCAGTGTTCCTGCACCATAAATGGCCACTTCAGGGCCAGTTCACTTGTCAGAATGTCAGCATTGACTTGGACTTCT
GCATTATTCTATATTAGTTACTTTTTGTTGCTGTGATAAAATTCTATAACCAAAAGCAACTTACAGGAGAGTTGATTATGCTCTGGTTCCAGGGGTGAGCCAACAAGGTAGGCATGGCAACAGGCATC
CATCCGGGTGGAAGTTGGCTTCACATTTCTGTTCATATGATCTTCCTACACAGCACCATCAGCTAGGGACCAAATGCTCAAATAACCAAACCAGTGGAGAATATTTCCCATACAAACCTCTCCAGCTG
CCAACCCATCCTCCTCCTCCTCACAGCTTTTGGTGGTGGCATGGACCACTCTAGACCGTCAGGTGAGAATGGATAATTGCTAAGTTAGAGGTGGATGGTGAGGGTGTGGGGTGGGGTTGCTGAAGGTC
CAGGTTCTGTAGCCGTATACACTTAGGGGGTGCGTTTAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGATTGTTACCCATGGAGATCAGAAGAGGGCATAGTATCCTATATAGCTGGAGTT
ACAGGGTATTGTGCACTACCTGAAGTGGTTGCTGGGAATTGAACTCATGACCTCTGGGAGAGCAGTTGGTGCTCTTAACCACTGAGCCATCTCTCCAGCCCCTATTGTGATTATTATATCCATAGTTT
TGTTAGATATTTTCTTTTGTGTGTTTAATTTTATTTTGAAGTATTTCATACTTGTAGGAAAATGGCCAGAGTGATGTAAACACTCCCTCTTCCTGTGCCCAATGACTACAGTTCTGATTTACCCTGTA
TTCTTTCTCTCTGTGGACACACACATTTACTGCTGGGTTTGTTTATTTTTATTTTGGTTTTCCTGGGTGTGTGTGCCTGTATGTGGGCATGTAGGTACTAGTGTTTATGTATGTTGGGGCTGGAGGGC
AACCTCCTGTGTGTTCCACGACTCTGTCCAGCTTATTTTTAATGATTTTGAGATGGGGCTTTTCACCTGGGGCTCACCTGTGGGCCAGGTGGCAGCCTCTGCGATGTCACAGTTCCTGAGCTTGCTTC
CCTTGCCCCCTGCCCTGGGGTTACTAGCACACACTGCAGTACCTGGCTTCCCCCCCAGCCCCCAAGCCCCACACAGGGTTTCTCTGTGTATCAGAGCTGGCTGTTCTGGAACTCCCCTTGTAGACCAG
GCTATCCTCAAACTCACAGAGATCCTCCTGCCTCCTCTGCCTCTGCCTCTATTTCTGTTGTTTCAATTACTGAATTCTGACTTACAAAAGCCCCACCCCACCCCCCTTCTCCACTAGTGTCTCATAGA
GCCCAGGCTAGCCTCAGTATGTAACTGAAGGTGATCTTGAACTTCCTGCCTCCTTCCCCGGTGCTGAGCTTATAAGTGTGCTACATTCTATTATTATAATAGTGTTATATTCCTGGGGGTGGAATCCA
GGGTTTATGTGTGCCAGGCAAACACTCTTCCAGCTAAGCTGCATTCCTAGCCCCTAATTTATAAAACTCCTTAAAGAGCTATAGGTTTGTTTCTTTAAAATGCATAATAGACTCCTTTTATTAGAGAG
GTATGGGCCTCCATCTTGCATTAGAGCTACTGTATCCAAAGTCAGGTACTGTGAGGAAGGGTCTGGCCAAGCTTAAGTGTCCTTAAGTCCCACACTCCATCCTAATCATTCTGGGTTAGTGAGGTTTG
GTGTGGCATGGGGCTGCCCTACCTCTGGTGGCCAGTTTGCAGTCCATTAGACAACATCCTTTGAAACCTGGAGTTGGTGATTGGCTGAGGTGGCTGTCAGTTTCAGGACTTGAGGGAGGGATCTGGGA
CTTAGTAGAGCATCTGTTTCCTAGAGTGACTTTGCCCACTTTCACAGTTGGTCCACATGGAGAGGATTTGAAACGAAGGTTGGTTTCCGTCTAGTTTTGTTTAGCATGCAAACAAAACCACTAGACTT
TTTTTTCTCAGCTATGAGATCAAAAGCCTTCTTTTCCAGATGACTAGAGCATGAAGTAAGTTGAGCCAACACTGCCACCTTACATAGGGCTTTGTTGGTATAAGGAACTCGGGATGTGACTTACATAC
ATTCTCAGGGAACATTGCCAAAGCCATGTAAGGAATCTGGGAATGGACGCCTCTCCCTCATAGTGTTACAGCTGAGCTCATGAACATGGCTTCAGAGCACAAGGAAGCTCTCATCATCCAGAGAGGAA
TACCAACCGCTCATTCCAGGGATTGATGGAGCCTTCACAGTGGCCTAAGGGCATGTGGTTCCTCCCAGCTGGAAGACTTACTGAGCCTCAGCCTCAGCTCCCACACCCACAAGGTATCAGGCTGCAGG
TATCTCTCCCCACCCCCGTTTCCATGCACGGCAGCTCCATGCCCAAGTAAAAACGGACCTTGTTCTGGTTCACACGGCATCCTAGGAGGTGAAGAAAACATGCGTGTAAAGATTACAAACTTTTCAAG
ATACCCAGAAGACAAAAATAAAGTCTCAGATGCAGCAGTTTATCCAAGTTTTGCTGTTTCTTTACCTCCTGCCTTTATACTACTTATTGTGTGTGGGGGGGGGGGGAGCATAAAATATTTATAACAAA
TCTCATATCATTTCATATCACCCCTGACATACTTTAGTAATTGTAACTTTTGAGACAGGTCTGACCTGGCGCTCTCTGGGGCTGTGGTTGACCTTGAACTCCTATACTCTACCTACCTTCCTAGTGCT
GAGGAATGGGCCACCACACCTGGGTTTTTGCAGTGTGGAGAACTGAACTGGGGGCTTAGGCATGCTTTGTAAGCACTCTCCCAACAGAGCGCATTCCCAGCTCCCTGTGTGGTCATTACTGATTTATT
TTGGAGAAAAGGTCTCACTGTGTAACCCAGGCCTCTCGCTCTTGTCCTGTGTCAGCAGCTTCCTGAGGGCTAGAGGGCCACAGGAGTGTGTTACTATGCCCACCTCCAAAATCATTTTTATGTATAGG
TTTTTATAATTCCTGTAATTGGTAATCCTACAACCCAAGAATCAAGCTGAACATGGTCACATCCACTTGTAATACCAGCATTAGGGAAGCTGAGGCAGGAGAATGGTGATTTTGAGGTCAGGCCGGAT
TGGACATGAAAGCAACACAGGAATCAACAAAGCCCCAACCAGACGCTTTAGAGAGACAGATCTGAACAAAGTTCCGTGGCTTGGCAGGGCAACAATCGGCTCACACTTGTGGGTCTACAGACTGGAAT
CGCAGCACGCTGTGTGTGTGAGCTCGCAGCTCGTTGTGTGTGAGCTCGGCTTCCTGTGCATTTCGGACGTCTGTCAATGACTGATCATTGTAACTTACAGGAATTTTTTAAACAATTTTTTAATTGAA
AAATCCCAGCCTCTGTCAGCTGCCAGCCTCCCAGCTTCTACTTCTGAGGAGCAGGAAGTGGGTGGGTAATGACAACGGGCCTGTAAACTGCGGACTCTAACCCGCCGATGACTCATCCGGTACAATGC
AGTATATTTGTCAAGGAGACTGAATCATATATGGGGGAAACTACTGCTCAGCAGCCAGCTGGTTCGCAGGTCAGCCTGAGAGGATCCATTTTTATCGGAAGCTTTATCGTAGCGATGATGCTAACGGG
CAGCCCTTGGACTCCACAATGTAGAGGAAATGGCATCTCCGGGCAGTGACAGCTATATTGTGCGTGTCAAGGCTGTGGTTATGACCAGAGATGACTCCAGCGGGGGATGGTTCCCACAGGAAGGAGGC
GGGATCAGTCGCGTCGGCGTGTGTAAGGTCATGCACCCTGAAGGCAACGGACGAAGCGGCTTTCTCATCCATGGCGAGCGACAGAAAGACAAACTGGTGGTATTGGAATGCTATGTCAGAAAGGACTT
GGTCTACACCAAAGCCAATCCGACGTTTCATCATTGGAAGGTTGATAACAGGAAGTTTGGACTTACTTTCCAAAGTCCTGCAGATGCACGAGCCTTTGACAGGGGCGTGAGAAAAGCCATTGAAGACC
TTATAGAAGGTTCAACGACCTCCTCTTCCACTCTCCATAACGAAGCTGAGCTCGGAGACGATGACGTTTTCACGACAGCTACGGACAGTTCTTCTAATTCCTCGCAGAAGAGGGAGCCGACTACGAGG
ACAATCTCCTCCCCCACGTCCTGTGAGCACCGGAAGATTTATACCCTTGACCCATACCCCATGGACCATTACCACCCTGACCAGCGGTTGCCGCGGTCCTACCCCCAGGTCACCTTCCCAGAAGATGA
TGAAGAAATTGTACGCATCAACCCCCGAGAGAAGATCTGGATGACCGGTTATGAAGACTACCGGCACGCGCCGGTTCGCGGCAAATACTTAGACACCACAGAAGACGCGGACTCCTACGTGCGCTTCG
CCAAGGGCGAAGTCCCCAAACACGAATATACCTATCCCTATGTTGATTCTTCGGACTTCGGCTTCGGGGAGGATCCCAAAGGTAGTGTGATCAAGACACAGCCGCCCAGGGCCAAGTCCCGTCGGCGG
AAGGAGAACGGCGAACGGTCGCGGTGTGTGTACTGCAGGGATATGTTTAATCACGAAGAGAACCGAAGGGGCCACTGCCAAGACGCGCCCGACGCCGTGAGAACTTGCATTCGCCGGGTGAGCTGTAT
GTGGTGCGCGGACAGCATGCTGTACCACTGTATGTCCGACCCCGAGGGAGACTACACTGACCCTTGTTCGTGTGACACAAGCGATGAGAAGTTTTGCCTCCGGTGGATGGCTCTAATTGCCTTGTCTT
TCCTGGCCCCTTGTATGTGCTGTTACCTGCCCCTCCGGGCCTGCCACCGCTGTGGAGTGATGTGCAGGTGCTGTGGTGGGAAGCACAAAGCCGCCGCGTGACTCGGTTCCCCTACTTTCTGCTTCTCC
ATCCACGGCCACGGGCAACTTGTCTCTTGCGCACTCCCCCATCCTCTCCCTGGTTCCCTTCCAACTCCAAAAGGCTAGGCCAATAAGAGGAGGCCAGGCTCTGTGGTCCCTTGGTGACATCATTCCAA
ACCTGGGGTAGCTGCCGCCCCCTGTGTCAGCCACATACCCCCTCTCGCAGTGTTCTGAGGAAAGGAGCCTTCGGCATAGACTCGTGTATTTTACCAGCCTATAATCGTGCTGAGTGTTGGTTTCCTGC
CCCTCCTTCCCACCTTTCTGGTTCTGCAGACTTGGAGGGGTTTATTGACTCTCCCCCCCCCTCCCCCGCTCTGTGACTTTTTTTTTTTTCTTCTCCCCATTGGGTTTGCCTGTCGCTAACTAGCATAG
GTCCCACAGAGATGTGACAGAATGATGAAGCCGGCACCACAGCATGTTGTTATGTGAGGAGGCAATCTGGATAGCAAGCATGTACCACAAAACAGTAGTACTTTAACCCCTAATGCCACGTCTCCCCA
TCAGCTGCCGGTTTTGTCTTTAACCTGCTATCATCTCTTCTCCTGCCCCTCCCTCCCCATGAATTAATTCACTAATGCAAAACAATCACTTTTTAAATGACTTTTTGAGCCTTAAATCCATATTCACT
TGTGAGAATCAGGAAAGAATTCCTCGAGTTGCTTTGCATCCTCTTGGACCAGGGCTTGCAAGGCGATTTGGGTTTCTGTGAGCTTGCCCAGTTGACCCGAAAAATAGGACTTTTTAGAATTGCATTGC
CACTTCTAAAATCCTAGCAATACTTAGAATAACACATCAGTGAGATAAATTTTACTCAATTATTTTACAAACCAAATTGAGTTATTCAAACACAAGCCAGTATTCTGTGAACAAGTTCCAGATGAAAA
ACACAGAAGTTGTGAATGAAGTTGTAGCCATTCCCTGCCCTGCACTATATTTTTCAGGGTGCATTTTAAATACTATTGATTCAAACAGTGGTGGCTTGCGTTTTTTTAGGTATATATTTTTGGTTAGT
TTTTTGGGGGGGGTTGTTTTGTTTTTTTAATTTGAGGCTCAATTCTTCATTTATACTTGAAAAAAACAAGGCCATATGTAAAGAAAAAAAAAAACCCTCTTTCAATGCCTAAGTGTCTTCTTCTATCA
CTCCACACCCACAGTTGCCACTTGGGGTGCACAGATAAGGGTAGGTCACCAACTGATTATGCCTGTCTCTGAGCCATGCAAGAGGCTCCTAATGTGCTGGGGGGGGGAGCACATATGCATATATATAT
ATGAGAATAGCCAACTTCTACAGAAAAAAGACAAGTGGAAGTGGTTTACCAATACCTAGCATGGTACAATCAGAGCTCCGTGGGGACTGTAGGGAGCAGGGTGTTACTACTGGCCGTTCTTCCCACAG
TGATTAACGGTAGAGATCAAGCTCAGTCCCCTTTATCCCCCCCCCCCCCCAAGCTCAGTCCCCTTTAGTCCTTCTTCCCCTCCCCCCTCCCCCATTGCACACAGACATCCGTCTTTAAAGGAAAAGGC
CTTTTTTCCAGTCAATCAGTCAGTCAGTCAGTCAGTCAGTCATACTGGGAGAAGCTAGCCTTGCATCCCTAGCACTGTCTCTTCCTGGCAGTGCTTTCTGCTCGCCCGACAGACAGCCTGTCGTGTCT
CTTTGGACAGACGGACCATCAGTGTAGATAATCAGCATGCTTGTGCATTACGTGGAGGTTGGAGGTGTCATCTTTGTTGGGATGACTGATTGGGGCTATCTGTTGTCAACAAGCGTCGTCTCCACCAT
TGTGGATGGAGGGGGTCTCTGTGCTAGGAGACTCTATAGACTGCCTCCAGCCGCCCTCCAGTGCTGTGGAGAGACTGTCCCCAGCCTGAGGGACTCTCCTCGGGCCCTCGCCTCTCTACCAAGCACAA
CACTAATCCTGTTTCCTTAAACCTCCGTTCAAGTGCCCCTATTTATTTCAGTGAGAATGCGTGTCCGGTTGCCTCTGTCCCTGTTTGTGCGTCCTTCCTCCCAGCCGGTTCCCACCCTCCTAAGGGTT
ATGCCAGTGGATCTCACGCCTCTGTGCATCACCTATCTTTGGTTTGTGAAGGCAGCAGTTAAGGGCACAAAGACAGCCATGGGGACATTTATGTAAATATGTTTAATTGCCACACTGCAGCTGAACGG
TGTGTAGTATTTTCCCAGTCAGCTTTGCCATACTGACGTCAATCATTTGAGAGAAATTATTCAGATTTTATTTTTATATCCATGGTAACAGAACCTAACCAAAAGGTTTCCCGTTCAGAAGTTTCCTT
AGCTCTCGTCCCAAGCTATTCGCTCACATTAACAAGTCAAAGTGCCTGAAGCATAACTCATTTACCTGTATACTAAAACCCCTGTTGTACTGATTTTTTTTTATAATAAGCCTTTTTACCTCTGTAAA
AATATATATATATACAAGTGTATGATGTACATTTTAGTTCTTAACTTTTTTATGGTTTCTAATATGTATGACCAATGTAGCCATTGCTTTGAAATGTAAATATAAACACGTCCTATCCGA

hide sequence

RefSeq Acc Id:

XM_036156236 ⟹ XP_036012129

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	11	19,931,989 - 19,974,026 (+)	NCBI

Sequence:

show sequence

GACTAGCCCAGGTGAGGACCAGTTCTTCCAGATCTCGGAGCTTTGTACATGAGCTGTGGCTGCTGCTCCCAGGGTGACCGTTGATGATGAACACCGTGAACCGTCAGCCCAGGTGACAGCTATATTGT
GCGTGTCAAGGCTGTGGTTATGACCAGAGATGACTCCAGCGGGGGATGGTTCCCACAGGAAGGAGGCGGGATCAGTCGCGTCGGCGTGTGTAAGGTCATGCACCCTGAAGGCAACGGACGAAGCGGCT
TTCTCATCCATGGCGAGCGACAGAAAGACAAACTGGTGGTATTGGAATGCTATGTCAGAAAGGACTTGGTCTACACCAAAGCCAATCCGACGTTTCATCATTGGAAGGTTGATAACAGGAAGTTTGGA
CTTACTTTCCAAAGTCCTGCAGATGCACGAGCCTTTGACAGGGGCGTGAGAAAAGCCATTGAAGACCTTATAGAAGGTTCAACGACCTCCTCTTCCACTCTCCATAACGAAGCTGAGCTCGGAGACGA
TGACGTTTTCACGACAGCTACGGACAGTTCTTCTAATTCCTCGCAGAAGAGGGAGCCGACTACGAGGACAATCTCCTCCCCCACGTCCTGTGAGCACCGGAAGATTTATACCCTTGACCCATACCCCA
TGGACCATTACCACCCTGACCAGCGGTTGCCGCGGTCCTACCCCCAGGTCACCTTCCCAGAAGATGATGAAGAAATTGTACGCATCAACCCCCGAGAGAAGATCTGGATGACCGGTTATGAAGACTAC
CGGCACGCGCCGGTTCGCGGCAAATACTTAGACACCACAGAAGACGCGGACTCCTACGTGCGCTTCGCCAAGGGCGAAGTCCCCAAACACGAATATACCTATCCCTATGTTGATTCTTCGGACTTCGG
CTTCGGGGAGGATCCCAAAGGTAGTGTGATCAAGACACAGCCGCCCAGGGCCAAGTCCCGTCGGCGGAAGGAGAACGGCGAACGGTCGCGGTGTGTGTACTGCAGGGATATGTTTAATCACGAAGAGA
ACCGAAGGGGCCACTGCCAAGACGCGCCCGACGCCGTGAGAACTTGCATTCGCCGGGTGAGCTGTATGTGGTGCGCGGACAGCATGCTGTACCACTGTATGTCCGACCCCGAGGGAGACTACACTGAC
CCTTGTTCGTGTGACACAAGCGATGAGAAGTTTTGCCTCCGGTGGATGGCTCTAATTGCCTTGTCTTTCCTGGCCCCTTGTATGTGCTGTTACCTGCCCCTCCGGGCCTGCCACCGCTGTGGAGTGAT
GTGCAGGTGCTGTGGTGGGAAGCACAAAGCCGCCGCGTGACTCGGTTCCCCTACTTTCTGCTTCTCCATCCACGGCCACGGGCAACTTGTCTCTTGCGCACTCCCCCATCCTCTCCCTGGTTCCCTTC
CAACTCCAAAAGGCTAGGCCAATAAGAGGAGGCCAGGCTCTGTGGTCCCTTGGTGACATCATTCCAAACCTGGGGTAGCTGCCGCCCCCTGTGTCAGCCACATACCCCCTCTCGCAGTGTTCTGAGGA
AAGGAGCCTTCGGCATAGACTCGTGTATTTTACCAGCCTATAATCGTGCTGAGTGTTGGTTTCCTGCCCCTCCTTCCCACCTTTCTGGTTCTGCAGACTTGGAGGGGTTTATTGACTCTCCCCCCCCC
TCCCCCGCTCTGTGACTTTTTTTTTTTTCTTCTCCCCATTGGGTTTGCCTGTCGCTAACTAGCATAGGTCCCACAGAGATGTGACAGAATGATGAAGCCGGCACCACAGCATGTTGTTATGTGAGGAG
GCAATCTGGATAGCAAGCATGTACCACAAAACAGTAGTACTTTAACCCCTAATGCCACGTCTCCCCATCAGCTGCCGGTTTTGTCTTTAACCTGCTATCATCTCTTCTCCTGCCCCTCCCTCCCCATG
AATTAATTCACTAATGCAAAACAATCACTTTTTAAATGACTTTTTGAGCCTTAAATCCATATTCACTTGTGAGAATCAGGAAAGAATTCCTCGAGTTGCTTTGCATCCTCTTGGACCAGGGCTTGCAA
GGCGATTTGGGTTTCTGTGAGCTTGCCCAGTTGACCCGAAAAATAGGACTTTTTAGAATTGCATTGCCACTTCTAAAATCCTAGCAATACTTAGAATAACACATCAGTGAGATAAATTTTACTCAATT
ATTTTACAAACCAAATTGAGTTATTCAAACACAAGCCAGTATTCTGTGAACAAGTTCCAGATGAAAAACACAGAAGTTGTGAATGAAGTTGTAGCCATTCCCTGCCCTGCACTATATTTTTCAGGGTG
CATTTTAAATACTATTGATTCAAACAGTGGTGGCTTGCGTTTTTTTAGGTATATATTTTTGGTTAGTTTTTTGGGGGGGGTTGTTTTGTTTTTTTAATTTGAGGCTCAATTCTTCATTTATACTTGAA
AAAAACAAGGCCATATGTAAAGAAAAAAAAAAACCCTCTTTCAATGCCTAAGTGTCTTCTTCTATCACTCCACACCCACAGTTGCCACTTGGGGTGCACAGATAAGGGTAGGTCACCAACTGATTATG
CCTGTCTCTGAGCCATGCAAGAGGCTCCTAATGTGCTGGGGGGGGGAGCACATATGCATATATATATATGAGAATAGCCAACTTCTACAGAAAAAAGACAAGTGGAAGTGGTTTACCAATACCTAGCA
TGGTACAATCAGAGCTCCGTGGGGACTGTAGGGAGCAGGGTGTTACTACTGGCCGTTCTTCCCACAGTGATTAACGGTAGAGATCAAGCTCAGTCCCCTTTATCCCCCCCCCCCCCCAAGCTCAGTCC
CCTTTAGTCCTTCTTCCCCTCCCCCCTCCCCCATTGCACACAGACATCCGTCTTTAAAGGAAAAGGCCTTTTTTCCAGTCAATCAGTCAGTCAGTCAGTCAGTCAGTCATACTGGGAGAAGCTAGCCT
TGCATCCCTAGCACTGTCTCTTCCTGGCAGTGCTTTCTGCTCGCCCGACAGACAGCCTGTCGTGTCTCTTTGGACAGACGGACCATCAGTGTAGATAATCAGCATGCTTGTGCATTACGTGGAGGTTG
GAGGTGTCATCTTTGTTGGGATGACTGATTGGGGCTATCTGTTGTCAACAAGCGTCGTCTCCACCATTGTGGATGGAGGGGGTCTCTGTGCTAGGAGACTCTATAGACTGCCTCCAGCCGCCCTCCAG
TGCTGTGGAGAGACTGTCCCCAGCCTGAGGGACTCTCCTCGGGCCCTCGCCTCTCTACCAAGCACAACACTAATCCTGTTTCCTTAAACCTCCGTTCAAGTGCCCCTATTTATTTCAGTGAGAATGCG
TGTCCGGTTGCCTCTGTCCCTGTTTGTGCGTCCTTCCTCCCAGCCGGTTCCCACCCTCCTAAGGGTTATGCCAGTGGATCTCACGCCTCTGTGCATCACCTATCTTTGGTTTGTGAAGGCAGCAGTTA
AGGGCACAAAGACAGCCATGGGGACATTTATGTAAATATGTTTAATTGCCACACTGCAGCTGAACGGTGTGTAGTATTTTCCCAGTCAGCTTTGCCATACTGACGTCAATCATTTGAGAGAAATTATT
CAGATTTTATTTTTATATCCATGGTAACAGAACCTAACCAAAAGGTTTCCCGTTCAGAAGTTTCCTTAGCTCTCGTCCCAAGCTATTCGCTCACATTAACAAGTCAAAGTGCCTGAAGCATAACTCAT
TTACCTGTATACTAAAACCCCTGTTGTACTGATTTTTTTTTATAATAAGCCTTTTTACCTCTGTAAAAATATATATATATACAAGTGTATGATGTACATTTTAGTTCTTAACTTTTTTATGGTTTCTA
ATATGTATGACCAATGTAGCCATTGCTTTGAAATGTAAATATAAACACGTCCTATCCGA

hide sequence


Protein RefSeqs	NP_277058	(Get FASTA)	NCBI Sequence Viewer
	XP_006514519	(Get FASTA)	NCBI Sequence Viewer
	XP_006514520	(Get FASTA)	NCBI Sequence Viewer
	XP_006514521	(Get FASTA)	NCBI Sequence Viewer
	XP_036012129	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH30460	(Get FASTA)	NCBI Sequence Viewer
	AAH66013	(Get FASTA)	NCBI Sequence Viewer
	BAB62849	(Get FASTA)	NCBI Sequence Viewer
	BAC29425	(Get FASTA)	NCBI Sequence Viewer
	EDL07825	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000090987
	ENSMUSP00000090987.6
	ENSMUSP00000159978
GenBank Protein	Q924S7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_277058 ⟸ NM_033523

- UniProtKB:

Q924S7 (UniProtKB/Swiss-Prot), Q5SRF8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTT
SSSTLHNEAELGDDDVFTTATDSSSNSSQKREPTTRTISSPTSCEHRKIYTLDPYPMDHYHPDQRLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDTTEDADSYVRFAKGEVPK
HEYTYPYVDSSDFGFGEDPKGSVIKTQPPRAKSRRRKENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMC
CYLPLRACHRCGVMCRCCGGKHKAAA

hide sequence

RefSeq Acc Id:	XP_006514519 ⟸ XM_006514456
- Peptide Label:	isoform X1
- UniProtKB:	Q5SRF8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSAFERFSVGNPRDEGSSQVIGDPDSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVM HPEGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTLHNEAELGDDDVFTTATDSSSNSSQKREPTTRTISSPTSCEHR KIYTLDPYPMDHYHPDQRLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDTTEDADSYVRFAKGEVPKHEYTYPYVDSSDFGFGEDPKGSVIKTQPPRAKSRRRKENGERSRCVY CRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHRCGVMCRCCGGKHKAAA hide sequence

RefSeq Acc Id:	XP_006514521 ⟸ XM_006514458
- Peptide Label:	isoform X3
- UniProtKB:	Q5SRF8 (UniProtKB/TrEMBL), A0AAQ4VMS6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASPGSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSS TLHNEAELGDDDVFTTATDSSSNSSQKREPTTRTISSPTSCEHRKIYTLDPYPMDHYHPDQRLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDTTEDADSYVRFAKGEVPKHEY TYPYVDSSDFGFGEDPKGSVIKTQPPRAKSRRRKENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYL PLRACHRCGVMCRCCGGKHKAAA hide sequence

RefSeq Acc Id:	XP_006514520 ⟸ XM_006514457
- Peptide Label:	isoform X2
- UniProtKB:	Q5SRF8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIGFTELTSDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQ KDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTLHNEAELGDDDVFTTATDSSSNSSQKREPTTRTISSPTSCEHRKIYTLDPYPMDHYHPDQ RLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDTTEDADSYVRFAKGEVPKHEYTYPYVDSSDFGFGEDPKGSVIKTQPPRAKSRRRKENGERSRCVYCRDMFNHEENRRGHCQD APDAVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHRCGVMCRCCGGKHKAAA hide sequence

Ensembl Acc Id:

ENSMUSP00000090988 ⟸ ENSMUST00000093299

Protein Domains

KBD SPR WH1

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q924S7-F1-model_v2	AlphaFold	Q924S7	1-410	view protein structure

RGD ID:

6822238

Promoter ID:

MM_KWN:6555

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day1, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6

Transcripts:

NM_033523, OTTMUST00000011644, UC007ICQ.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	19,824,181 - 19,824,832 (+)	MPROMDB

RGD ID:

6846911

Promoter ID:

MM_ACW:6831

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Kidney

Transcripts:

SPRED2.FSEP07, SPRED2.ISEP07-UNSPLICED

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	11	19,897,941 - 19,898,441 (+)	MPROMDB

RGD ID:

8674044

Promoter ID:

EPDNEW_M15052

Type:

initiation region

Name:

Spred2_1

Description:

Mus musculus sprouty-related, EVH1 domain containing 2 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	11	19,924,417 - 19,924,477	EPDNEW

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000045671	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000093298	ENTREZGENE
	ENSMUST00000093298.12	UniProtKB/Swiss-Prot
	ENSMUST00000249881	ENTREZGENE
Gene3D-CATH	2.30.29.30	UniProtKB/Swiss-Prot
InterPro	KBD	UniProtKB/Swiss-Prot
	PH-like_dom_sf	UniProtKB/Swiss-Prot
	SPRE_EVH1	UniProtKB/Swiss-Prot
	Sprouty	UniProtKB/Swiss-Prot
	WH1/EVH1_dom	UniProtKB/Swiss-Prot
KEGG Report	mmu:114716	UniProtKB/Swiss-Prot
MGD	MGI:2150019	ENTREZGENE
NCBI Gene	114716	ENTREZGENE
PANTHER	SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2	UniProtKB/Swiss-Prot
	SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER	UniProtKB/Swiss-Prot
Pfam	Sprouty	UniProtKB/Swiss-Prot
	WH1	UniProtKB/Swiss-Prot
PhenoGen	Spred2	PhenoGen
PROSITE	KBD	UniProtKB/Swiss-Prot
	SPR	UniProtKB/Swiss-Prot
	WH1	UniProtKB/Swiss-Prot
SMART	WH1	UniProtKB/Swiss-Prot
Superfamily-SCOP	PH domain-like	UniProtKB/Swiss-Prot
UniProt	A0AAQ4VMS6	ENTREZGENE, UniProtKB/TrEMBL
	Q5SRF8	ENTREZGENE, UniProtKB/TrEMBL
	Q5SRF9_MOUSE	UniProtKB/TrEMBL
	Q8K2N1_MOUSE	UniProtKB/TrEMBL
	Q924S7	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-03-26	Spred2	sprouty-related EVH1 domain containing 2		sprouty-related, EVH1 domain containing 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Mammalian Phenotype