(-)-epigallocatechin 3-gallate multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SPRED2 mRNA CTD PMID:22079256 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of SPRED2 mRNA CTD PMID:22206623 17beta-estradiol decreases expression ISO Spred2 (Rattus norvegicus) 6480464 Estradiol results in decreased expression of SPRED2 mRNA CTD PMID:20068009 and PMID:32145629 17beta-estradiol decreases expression ISO SPRED2 (Homo sapiens) 6480464 Estradiol results in decreased expression of SPRED2 mRNA CTD PMID:19167446 17beta-estradiol increases expression ISO SPRED2 (Homo sapiens) 6480464 Estradiol results in increased expression of SPRED2 mRNA CTD PMID:23019147 and PMID:31614463 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [2 more ... CTD PMID:32653021 2,3',4,4',5-Pentachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SPRED2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Spred2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of SPRED2 mRNA CTD PMID:33387578 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Spred2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:32109520 2-hydroxypropanoic acid increases expression ISO SPRED2 (Homo sapiens) 6480464 Lactic Acid results in increased expression of SPRED2 mRNA CTD PMID:30851411 2-methylcholine affects expression ISO SPRED2 (Homo sapiens) 6480464 beta-methylcholine affects the expression of SPRED2 mRNA CTD PMID:21179406 2-palmitoylglycerol increases expression ISO SPRED2 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of SPRED2 mRNA CTD PMID:37199045 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of SPRED2 mRNA CTD PMID:20713471 acetamide decreases expression ISO Spred2 (Rattus norvegicus) 6480464 acetamide results in decreased expression of SPRED2 mRNA CTD PMID:31881176 aflatoxin B1 affects expression ISO SPRED2 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of SPRED2 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO SPRED2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of SPRED2 gene CTD PMID:27153756 all-trans-retinoic acid increases expression ISO Spred2 (Rattus norvegicus) 6480464 Tretinoin results in increased expression of SPRED2 mRNA CTD PMID:20488242 atrazine decreases expression ISO SPRED2 (Homo sapiens) 6480464 Atrazine results in decreased expression of SPRED2 mRNA CTD PMID:22378314 atrazine affects methylation ISO Spred2 (Rattus norvegicus) 6480464 Atrazine affects the methylation of SPRED2 gene CTD PMID:35440735 azoxystrobin decreases expression ISO SPRED2 (Homo sapiens) 6480464 azoxystrobin results in decreased expression of SPRED2 mRNA CTD PMID:33512557 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of SPRED2 mRNA CTD PMID:19770486 benzo[a]pyrene increases expression ISO SPRED2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of SPRED2 mRNA CTD PMID:32234424 benzo[a]pyrene diol epoxide I affects expression ISO SPRED2 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 benzo[a]pyrene diol epoxide I decreases expression ISO SPRED2 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 benzoates decreases expression ISO SPRED2 (Homo sapiens) 6480464 Benzoates analog results in decreased expression of SPRED2 mRNA CTD PMID:29472718 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of SPRED2 mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of SPRED2 mRNA] CTD PMID:19850644 bisphenol A decreases expression ISO Spred2 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of SPRED2 mRNA CTD PMID:25181051 and PMID:32145629 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SPRED2 mRNA CTD PMID:32156529 bisphenol A multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SPRED2 gene CTD PMID:31601247 bisphenol A increases methylation ISO Spred2 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of SPRED2 gene CTD PMID:28505145 bisphenol F multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [bisphenol F co-treated with Fulvestrant] results in increased methylation of SPRED2 gene CTD PMID:31601247 buta-1,3-diene decreases expression EXP 6480464 1 and 3-butadiene results in decreased expression of SPRED2 mRNA CTD PMID:29038090 butanal decreases expression ISO SPRED2 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of SPRED2 mRNA CTD PMID:26079696 cadmium atom multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SPRED2 mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SPRED2 mRNA CTD PMID:35301059 caffeine increases phosphorylation ISO SPRED2 (Homo sapiens) 6480464 Caffeine results in increased phosphorylation of SPRED2 protein CTD PMID:35688186 carbamazepine affects expression ISO SPRED2 (Homo sapiens) 6480464 Carbamazepine affects the expression of SPRED2 mRNA CTD PMID:25979313 carbon nanotube decreases expression EXP 6480464 Nanotubes and Carbon results in decreased expression of SPRED2 mRNA CTD PMID:25620056 CGP 52608 multiple interactions ISO SPRED2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to SPRED2 gene] CTD PMID:28238834 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SPRED2 gene CTD PMID:20938992 coumestrol decreases expression ISO SPRED2 (Homo sapiens) 6480464 Coumestrol results in decreased expression of SPRED2 mRNA CTD PMID:19167446 coumestrol multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SPRED2 mRNA CTD PMID:19167446 crocidolite asbestos affects expression ISO SPRED2 (Homo sapiens) 6480464 Asbestos and Crocidolite affects the expression of SPRED2 mRNA CTD PMID:17331233 cyclosporin A increases expression ISO SPRED2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of SPRED2 mRNA CTD PMID:20106945 DDT decreases methylation ISO Spred2 (Rattus norvegicus) 6480464 DDT results in decreased methylation of SPRED2 gene CTD PMID:31682807 deguelin increases expression ISO SPRED2 (Homo sapiens) 6480464 deguelin results in increased expression of SPRED2 mRNA CTD PMID:33512557 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of SPRED2 mRNA CTD PMID:21266533 dicrotophos increases expression ISO SPRED2 (Homo sapiens) 6480464 dicrotophos results in increased expression of SPRED2 mRNA CTD PMID:28302478 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of SPRED2 mRNA CTD PMID:15171707 divanadium pentaoxide affects expression ISO SPRED2 (Homo sapiens) 6480464 vanadium pentoxide affects the expression of SPRED2 mRNA CTD PMID:17459161 dorsomorphin multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPRED2 mRNA CTD PMID:27188386 doxorubicin decreases expression ISO SPRED2 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of SPRED2 mRNA CTD PMID:29803840 Enterolactone multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SPRED2 mRNA CTD PMID:19167446 epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of SPRED2 mRNA CTD PMID:35436446 ethanol affects splicing EXP 6480464 Ethanol affects the splicing of SPRED2 mRNA CTD PMID:30319688 ethanol affects expression EXP 6480464 Ethanol affects the expression of SPRED2 mRNA CTD PMID:30319688 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SPRED2 gene CTD PMID:20938992 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of SPRED2 mRNA CTD PMID:25629700 formaldehyde decreases expression ISO SPRED2 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of SPRED2 mRNA CTD PMID:20655997 FR900359 decreases phosphorylation ISO SPRED2 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of SPRED2 protein CTD PMID:37730182 fulvestrant multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SPRED2 gene and [bisphenol F co-treated with Fulvestrant] results in increased methylation of SPRED2 gene CTD PMID:31601247 inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SPRED2 mRNA CTD PMID:36331819 isotretinoin increases expression ISO SPRED2 (Homo sapiens) 6480464 Isotretinoin results in increased expression of SPRED2 mRNA CTD PMID:20436886 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SPRED2 gene CTD PMID:20938992 lead(0) decreases expression ISO SPRED2 (Homo sapiens) 6480464 Lead results in decreased expression of SPRED2 mRNA CTD PMID:19921347 leflunomide increases expression ISO SPRED2 (Homo sapiens) 6480464 leflunomide results in increased expression of SPRED2 mRNA CTD PMID:28988120 methyl methanesulfonate decreases expression ISO SPRED2 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of SPRED2 mRNA CTD PMID:23649840 methylmercury chloride increases expression ISO SPRED2 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of SPRED2 mRNA CTD PMID:28001369 N,N-diethyl-m-toluamide multiple interactions ISO Spred2 (Rattus norvegicus) 6480464 [Permethrin co-treated with DEET] results in decreased methylation of SPRED2 gene CTD PMID:33148267 nitrofen decreases expression ISO Spred2 (Rattus norvegicus) 6480464 nitrofen results in decreased expression of SPRED2 mRNA CTD PMID:23982388 and PMID:26720608 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of SPRED2 mRNA CTD PMID:34911549 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of SPRED2 mRNA CTD PMID:17562736 paracetamol decreases expression ISO Spred2 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of SPRED2 mRNA CTD PMID:33387578 paracetamol increases expression ISO SPRED2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of SPRED2 mRNA CTD PMID:29067470 paracetamol decreases expression ISO SPRED2 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of SPRED2 mRNA CTD PMID:21420995 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SPRED2 mRNA CTD PMID:36331819 permethrin multiple interactions ISO Spred2 (Rattus norvegicus) 6480464 [Permethrin co-treated with DEET] results in decreased methylation of SPRED2 gene CTD PMID:33148267 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of SPRED2 mRNA CTD PMID:17950772 potassium chromate increases expression ISO SPRED2 (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of SPRED2 mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of SPRED2 mRNA CTD PMID:22079256 potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of SPRED2 mRNA CTD PMID:23608068 rac-lactic acid increases expression ISO SPRED2 (Homo sapiens) 6480464 Lactic Acid results in increased expression of SPRED2 mRNA CTD PMID:30851411 SB 431542 multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPRED2 mRNA CTD PMID:27188386 silver atom increases expression ISO SPRED2 (Homo sapiens) 6480464 Silver results in increased expression of SPRED2 mRNA CTD PMID:28959546 silver atom increases expression EXP 6480464 Silver results in increased expression of SPRED2 mRNA CTD PMID:27131904 silver(0) increases expression ISO SPRED2 (Homo sapiens) 6480464 Silver results in increased expression of SPRED2 mRNA CTD PMID:28959546 silver(0) increases expression EXP 6480464 Silver results in increased expression of SPRED2 mRNA CTD PMID:27131904 sulforaphane increases expression ISO SPRED2 (Homo sapiens) 6480464 sulforaphane results in increased expression of SPRED2 mRNA CTD PMID:31838189 sunitinib increases expression ISO SPRED2 (Homo sapiens) 6480464 Sunitinib results in increased expression of SPRED2 mRNA CTD PMID:31533062 tert-butyl hydroperoxide increases expression ISO SPRED2 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of SPRED2 mRNA CTD PMID:15336504 thifluzamide increases expression ISO SPRED2 (Homo sapiens) 6480464 thifluzamide results in increased expression of SPRED2 mRNA CTD PMID:33512557 trichostatin A decreases expression ISO SPRED2 (Homo sapiens) 6480464 trichostatin A results in decreased expression of SPRED2 mRNA CTD PMID:24935251 and PMID:26272509 trichostatin A multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPRED2 mRNA CTD PMID:27188386 trovafloxacin multiple interactions EXP 6480464 [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of SPRED2 mRNA CTD PMID:18930950 tunicamycin decreases expression ISO SPRED2 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of SPRED2 mRNA CTD PMID:29453283 urethane increases expression ISO SPRED2 (Homo sapiens) 6480464 Urethane results in increased expression of SPRED2 mRNA CTD PMID:28818685 valproic acid decreases methylation ISO SPRED2 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of SPRED2 gene CTD PMID:29154799 valproic acid increases expression ISO SPRED2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of SPRED2 mRNA CTD PMID:24935251 vinclozolin decreases expression ISO Spred2 (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of SPRED2 mRNA CTD PMID:23034163 zinc atom multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SPRED2 mRNA CTD PMID:18593933 zinc(0) multiple interactions ISO SPRED2 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SPRED2 mRNA CTD PMID:18593933