Tmeff2 (transmembrane protein with EGF-like and two follistatin-like domains 2) - Rat Genome Database

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Gene: Tmeff2 (transmembrane protein with EGF-like and two follistatin-like domains 2) Mus musculus
Analyze
Symbol: Tmeff2
Name: transmembrane protein with EGF-like and two follistatin-like domains 2
RGD ID: 1318844
MGI Page MGI
Description: Predicted to be involved in cell differentiation. Predicted to act upstream of or within negative regulation of cell migration; negative regulation of cellular component organization; and wound healing, spreading of cells. Predicted to be located in membrane. Predicted to be active in extracellular region. Is expressed in several structures, including gut; nervous system; prostate gland; vibrissa; and white fat. Human ortholog(s) of this gene implicated in prostate cancer and urinary bladder cancer. Orthologous to human TMEFF2 (transmembrane protein with EGF like and two follistatin like domains 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4832418D20Rik; 7630402F16Rik; RIKEN cDNA 7630402F16 gene; tomoregulin-2; TR-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39150,951,946 - 51,226,429 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl150,939,806 - 51,226,429 (+)EnsemblGRCm39 Ensembl
GRCm38150,900,683 - 51,187,270 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl150,900,647 - 51,187,270 (+)EnsemblGRCm38mm10GRCm38
MGSCv37150,984,367 - 51,244,114 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36150,872,068 - 51,131,815 (+)NCBIMGSCv36mm8
Celera151,227,901 - 51,485,691 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map125.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmeff2MouseBreast Neoplasms  ISOTMEFF2 (Homo sapiens)2290489DNA:hypermethylation:promoterRGD 
Tmeff2Mouseprostate cancer  ISOTMEFF2 (Homo sapiens)2290486DNA:hypermethylationRGD 
Tmeff2Mouseprostate cancer disease_progressionISOTMEFF2 (Homo sapiens)2290485 RGD 
Tmeff2Mouseprostate cancer  ISOTMEFF2 (Homo sapiens)2290490 RGD 
Tmeff2Mouseurinary bladder cancer  ISOTMEFF2 (Homo sapiens)2290489DNA:hypermethylation:promoterRGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmeff2MouseNeurodevelopmental Disorders  ISOTMEFF2 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmeff2Mousepolycystic ovary syndrome  ISOTMEFF2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21411543
Tmeff2MouseProstatic Neoplasms  ISOTMEFF2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23405127

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmeff2Mouse1-naphthyl isothiocyanate decreases expressionISOTmeff2 (Rattus norvegicus)64804641-Naphthylisothiocyanate results in decreased expression of TMEFF2 mRNACTDPMID:30723492
Tmeff2Mouse17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of TMEFF2 mRNACTDPMID:19484750
Tmeff2Mouse17beta-hydroxy-5alpha-androstan-3-one increases expressionISOTMEFF2 (Homo sapiens)6480464Dihydrotestosterone results in increased expression of TMEFF2 mRNA and Dihydrotestosterone results in increased expression of TMEFF2 proteinCTDPMID:23405127 and PMID:29581250
Tmeff2Mouse17beta-hydroxy-5alpha-androstan-3-one multiple interactionsISOTMEFF2 (Homo sapiens)6480464AR protein affects the reaction [Dihydrotestosterone results in increased expression of TMEFF2 protein] more ...CTDPMID:23405127
Tmeff2Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of TMEFF2 mRNACTDPMID:26290441
Tmeff2Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionISOTMEFF2 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of TMEFF2 mRNACTDPMID:29704546
Tmeff2Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of TMEFF2 mRNACTDPMID:32553695
Tmeff2Mouse2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionEXP 64804642 more ...CTDPMID:38648751
Tmeff2Mouse6-propyl-2-thiouracil decreases expressionISOTmeff2 (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of TMEFF2 mRNACTDPMID:30047161
Tmeff2Mouse7,12-dimethyltetraphene increases expressionEXP 64804649 more ...CTDPMID:32553695
Tmeff2Mouseactinomycin D multiple interactionsISOTMEFF2 (Homo sapiens)6480464Dactinomycin inhibits the reaction [Dihydrotestosterone results in increased expression of TMEFF2 mRNA]CTDPMID:23405127
Tmeff2Mouseaflatoxin B1 decreases methylationISOTMEFF2 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of TMEFF2 geneCTDPMID:27153756
Tmeff2Mouseall-trans-retinoic acid increases expressionEXP 6480464Tretinoin results in increased expression of TMEFF2 mRNACTDPMID:16604517
Tmeff2Mouseall-trans-retinoic acid multiple interactionsEXP 6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of TMEFF2 mRNACTDPMID:36189433
Tmeff2Mouseall-trans-retinoic acid increases expressionISOTMEFF2 (Homo sapiens)6480464Tretinoin results in increased expression of TMEFF2 mRNACTDPMID:21934132 and PMID:33167477
Tmeff2Mouseamitrole decreases expressionISOTmeff2 (Rattus norvegicus)6480464Amitrole results in decreased expression of TMEFF2 mRNACTDPMID:30047161
Tmeff2Mousearsane affects methylationISOTMEFF2 (Homo sapiens)6480464Arsenic affects the methylation of TMEFF2 geneCTDPMID:25304211
Tmeff2Mousearsane multiple interactionsISOTMEFF2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of TMEFF2 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TMEFF2 mRNACTDPMID:39836092
Tmeff2Mousearsenic atom affects methylationISOTMEFF2 (Homo sapiens)6480464Arsenic affects the methylation of TMEFF2 geneCTDPMID:25304211
Tmeff2Mousearsenic atom multiple interactionsISOTMEFF2 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of TMEFF2 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of TMEFF2 mRNACTDPMID:39836092

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Biological Process

  

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tmeff2Mouseextracellular region is_active_inIBAPANTHER:PTN000099217 more ...2290270 GO_CentralGO_REF:0000033
Tmeff2Mousemembrane located_inIEAUniProtKB-SubCell:SL-01622290270 UniProtGO_REF:0000044

Molecular Function

  


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Reference Title
Reference Citation
1. Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer. Afar DE, etal., Mol Cancer Ther. 2004 Aug;3(8):921-32.
2. Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo. Chen Q, etal., Cancer Lett. 2006 Dec 8;244(2):274-88. Epub 2006 Feb 23.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers. Suzuki M, etal., Br J Cancer. 2005 Oct 31;93(9):1029-37.
9. Methylation of apoptosis related genes in the pathogenesis and prognosis of prostate cancer. Suzuki M, etal., Cancer Lett. 2006 Oct 28;242(2):222-30. Epub 2006 Feb 3.
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PMID:10349636   PMID:10600548   PMID:10903839   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12878679   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16632597  
PMID:17698011   PMID:20562862   PMID:21267068   PMID:21677750   PMID:21862448   PMID:21873635   PMID:22828515   PMID:24632071   PMID:26402097   PMID:28336932   PMID:33795231  



Tmeff2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39150,951,946 - 51,226,429 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl150,939,806 - 51,226,429 (+)EnsemblGRCm39 Ensembl
GRCm38150,900,683 - 51,187,270 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl150,900,647 - 51,187,270 (+)EnsemblGRCm38mm10GRCm38
MGSCv37150,984,367 - 51,244,114 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36150,872,068 - 51,131,815 (+)NCBIMGSCv36mm8
Celera151,227,901 - 51,485,691 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map125.95NCBI
TMEFF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382191,949,046 - 192,194,933 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2191,949,043 - 192,194,933 (-)EnsemblGRCh38hg38GRCh38
GRCh372192,813,772 - 193,059,659 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362192,522,988 - 192,767,889 (-)NCBINCBI36Build 36hg18NCBI36
Build 342192,640,254 - 192,885,150NCBI
Celera2186,409,789 - 186,655,054 (-)NCBICelera
Cytogenetic Map2q32.3NCBI
HuRef2184,672,895 - 184,920,068 (-)NCBIHuRef
CHM1_12192,820,711 - 193,065,780 (-)NCBICHM1_1
T2T-CHM13v2.02192,437,261 - 192,683,624 (-)NCBIT2T-CHM13v2.0
Tmeff2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8957,937,873 - 58,225,372 (-)NCBIGRCr8
mRatBN7.2950,445,947 - 50,733,473 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl950,436,079 - 50,733,475 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx958,992,474 - 59,279,503 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0964,115,319 - 64,402,348 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0962,411,281 - 62,698,306 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0955,379,130 - 55,673,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl955,384,100 - 55,673,829 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0955,079,810 - 55,369,414 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4947,519,306 - 47,811,472 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1947,522,306 - 47,812,884 (-)NCBI
Celera948,081,045 - 48,369,704 (-)NCBICelera
Cytogenetic Map9q22NCBI
Tmeff2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554037,121,834 - 7,354,908 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554037,122,019 - 7,353,769 (+)NCBIChiLan1.0ChiLan1.0
TMEFF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21394,623,048 - 94,863,209 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B94,638,032 - 94,878,190 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B79,242,825 - 79,489,113 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B197,157,426 - 197,397,439 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B197,158,689 - 197,396,254 (-)Ensemblpanpan1.1panPan2
TMEFF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1372,414,208 - 2,635,283 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl372,414,440 - 2,635,431 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha373,361,937 - 3,582,835 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0372,303,017 - 2,524,548 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl372,303,191 - 2,524,547 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1372,312,184 - 2,533,428 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0372,279,821 - 2,500,794 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0372,292,309 - 2,514,442 (-)NCBIUU_Cfam_GSD_1.0
Tmeff2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303150,461,820 - 150,724,361 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365066,114,108 - 6,355,200 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365066,113,521 - 6,375,986 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEFF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1596,594,970 - 96,855,743 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11596,594,901 - 96,856,848 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215108,167,977 - 108,396,883 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEFF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11077,491,041 - 77,735,890 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1077,490,095 - 77,735,849 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040121,733,118 - 121,975,654 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmeff2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248544,021,094 - 4,250,812 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248544,021,022 - 4,249,757 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Tmeff2
13132 total Variants

Predicted Target Of
Summary Value
Count of predictions:630
Count of miRNA genes:376
Interacting mature miRNAs:459
Transcripts:ENSMUST00000081851, ENSMUST00000114565, ENSMUST00000139157
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 40 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357524W6q14_mweight 6 weeks QTL 14 (mouse)Not determined13476013873976915Mouse
12910788Pwgrq9_mpost-weaning growth rate QTL 9 (mouse)14086800867270256Mouse
1301714Vertcling_mvertical clinging (mouse)Not determined14293803176938167Mouse
1301073Orch5_mautoimmune orchitis resistance 5 (mouse)Not determined11906535153065454Mouse
18182931Metl1_mmetabolite locus 1, pyridoxate (mouse)14127539975275399Mouse
1357651Lgq5_mlate growth QTL 5 (mouse)Not determined13476013873976915Mouse
12910786Pwgrq10_mpost-weaning growth rate QTL 10 (mouse)14086800867270256Mouse
11100001Col4a1m1_mcollagen, type IV, alpha 1 modifier 1 (mouse)12555019162946882Mouse
1301211Bbaa11_mB.burgdorferi-associated arthritis 11 (mouse)Not determined14888900682889210Mouse

1 to 10 of 40 rows






Ensembl Acc Id: ENSMUST00000081851   ⟹   ENSMUSP00000080533
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl150,966,678 - 51,226,429 (+)Ensembl
GRCm38.p6 Ensembl150,927,519 - 51,187,270 (+)Ensembl
Ensembl Acc Id: ENSMUST00000114565   ⟹   ENSMUSP00000110212
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl150,949,121 - 51,019,079 (+)Ensembl
GRCm38.p6 Ensembl150,909,962 - 50,979,920 (+)Ensembl
Ensembl Acc Id: ENSMUST00000139157
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl150,939,806 - 50,954,589 (+)Ensembl
GRCm38.p6 Ensembl150,900,647 - 50,915,430 (+)Ensembl
Ensembl Acc Id: ENSMUST00000186103
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl150,939,806 - 50,953,084 (+)Ensembl
GRCm38.p6 Ensembl150,900,647 - 50,913,925 (+)Ensembl
RefSeq Acc Id: NM_019790   ⟹   NP_062764
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39150,966,682 - 51,226,429 (+)NCBI
GRCm38150,927,523 - 51,187,270 (+)NCBI
MGSCv37150,984,367 - 51,244,114 (+)RGD
Celera151,227,901 - 51,485,691 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030255650   ⟹   XP_030111510
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39150,951,946 - 51,226,063 (+)NCBI
GRCm38150,900,683 - 51,186,904 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152485   ⟹   XP_036008378
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39150,951,946 - 51,226,063 (+)NCBI
Sequence:
RefSeq Acc Id: NP_062764   ⟸   NM_019790
- Peptide Label: precursor
- UniProtKB: Q8CDH1 (UniProtKB/Swiss-Prot),   Q3UY20 (UniProtKB/Swiss-Prot),   Q9JJE3 (UniProtKB/Swiss-Prot),   Q9QYM9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030111510   ⟸   XM_030255650
- Peptide Label: isoform X1
- UniProtKB: Q9QYM9 (UniProtKB/Swiss-Prot),   Q8CDH1 (UniProtKB/Swiss-Prot),   Q3UY20 (UniProtKB/Swiss-Prot),   Q9JJE3 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000080533   ⟸   ENSMUST00000081851
Ensembl Acc Id: ENSMUSP00000110212   ⟸   ENSMUST00000114565
RefSeq Acc Id: XP_036008378   ⟸   XM_036152485
- Peptide Label: isoform X2
EGF-like   Kazal-like

Name Modeler Protein Id AA Range Protein Structure
AF-Q9QYM9-F1-model_v2 AlphaFold Q9QYM9 1-374 view protein structure

RGD ID:6873652
Promoter ID:EPDNEW_M277
Type:multiple initiation site
Name:Tmeff2_1
Description:Mus musculus transmembrane protein with EGF-like and two follistatin-likedomains 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38150,927,536 - 50,927,596EPDNEW
RGD ID:6818593
Promoter ID:MM_KWN:672
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   ES_Cell,   MEF_B4
Transcripts:ENSMUST00000114567,   OTTMUST00000053512
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36150,984,076 - 50,984,576 (+)MPROMDB


1 to 30 of 30 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000026109 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000081851 ENTREZGENE
  ENSMUST00000081851.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.60.30 UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
InterPro EGF-like_dom UniProtKB/Swiss-Prot
  Kazal_dom UniProtKB/Swiss-Prot
  Kazal_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:56363 UniProtKB/Swiss-Prot
MGD MGI:1861735 ENTREZGENE
NCBI Gene 56363 ENTREZGENE
PANTHER TRANSMEMBRANE PROTEIN WITH EGF LIKE AND TWO FOLLISTATIN LIKE DOMAINS 2 UniProtKB/Swiss-Prot
  UNCHARACTERIZED UniProtKB/Swiss-Prot
Pfam Kazal_2 UniProtKB/Swiss-Prot
PhenoGen Tmeff2 PhenoGen
PROSITE EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  KAZAL_2 UniProtKB/Swiss-Prot
SMART KAZAL UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
  SSF100895 UniProtKB/Swiss-Prot
UniProt A0A0R4J1J9_MOUSE UniProtKB/TrEMBL
  Q3UY20 ENTREZGENE
  Q8CDH1 ENTREZGENE
  Q9JJE3 ENTREZGENE
  Q9QYM9 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3UY20 UniProtKB/Swiss-Prot
  Q8CDH1 UniProtKB/Swiss-Prot
  Q9JJE3 UniProtKB/Swiss-Prot
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 Tmeff2  transmembrane protein with EGF-like and two follistatin-like domains 2  7630402f16rik  RIKEN cDNA 7630402F16 gene  Data merged from RGD:1609130 737654 PROVISIONAL