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Gene: Rtl1 (retrotransposon Gaglike 1) Mus musculus

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Symbol:

Rtl1

Name:

retrotransposon Gaglike 1

RGD ID:

1316561

MGI Page

MGI

Description:

Involved in several processes, including placenta development; skeletal muscle satellite cell proliferation; and skeletal muscle tissue development. Acts upstream of or within angiogenesis and labyrinthine layer development. Is active in Z disc. Is expressed in several structures, including diaphragm; genitourinary system; immune system; musculature; and neocortex layer. Orthologous to human RTL1 (retrotransposon Gag like 1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

6430411K18Rik; M; mammalian retrotransposon derived protein 1; Mar; Mart1; Mo; Mor1; paternally expressed gene 11 protein; Peg11; retrotransposon-derived protein PEG11; retrotransposon-like 1; retrotransposon-like protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RTL1 (retrotransposon Gag like 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OrthoDB, Treefam
Rattus norvegicus (Norway rat):	Rtl1 (retrotransposon-like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rtl1 (retrotransposon Gag like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RTL1 (retrotransposon Gag like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RTL1 (retrotransposon Gag like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rtl1 (retrotransposon Gag like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RTL1 (retrotransposon Gag like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RTL1 (retrotransposon Gag like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rtl1 (retrotransposon Gag like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	RTL1 (retrotransposon Gag like 1)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	109,531,141 - 109,570,852 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	109,555,627 - 109,566,764 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	109,564,900 - 109,604,418 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	109,589,193 - 109,600,330 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	110,828,379 - 110,833,613 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	110,037,976 - 110,043,210 (-)	NCBI		MGSCv36	mm8
Celera	12	110,784,688 - 110,790,104 (-)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	60.38	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rtl1	Mouse	Kagami-Ogata syndrome		ISO	RTL1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Paternal uniparental disomy 14	ClinVar	PMID:18176563

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rtl1	Mouse	(-)-alpha-phellandrene	decreases expression	ISO	RTL1 (Homo sapiens)	6480464	alpha phellandrene results in decreased expression of RTL1 mRNA	CTD	PMID:25075043
Rtl1	Mouse	3,4-methylenedioxymethamphetamine	decreases expression	EXP		6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of RTL1 mRNA	CTD	PMID:20188158
Rtl1	Mouse	3,7-dihydropurine-6-thione	decreases expression	ISO	Rtl1 (Rattus norvegicus)	6480464	Mercaptopurine results in decreased expression of RTL1 mRNA	CTD	PMID:23358152
Rtl1	Mouse	alpha-phellandrene	decreases expression	ISO	RTL1 (Homo sapiens)	6480464	alpha phellandrene results in decreased expression of RTL1 mRNA	CTD	PMID:25075043
Rtl1	Mouse	benzo[a]pyrene	decreases expression	EXP		6480464	Benzo(a)pyrene results in decreased expression of RTL1 mRNA	CTD	PMID:27195522
Rtl1	Mouse	benzo[a]pyrene	affects methylation	ISO	RTL1 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of RTL1 promoter	CTD	PMID:27901495
Rtl1	Mouse	bis(2-ethylhexyl) phthalate	affects expression	EXP		6480464	Diethylhexyl Phthalate affects the expression of RTL1 mRNA and Diethylhexyl Phthalate affects the expression of RTL1 mRNA alternative form	CTD	PMID:21636974
Rtl1	Mouse	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of RTL1 mRNA and bisphenol A affects the expression of RTL1 mRNA alternative form	CTD	PMID:21636974
Rtl1	Mouse	bisphenol A	decreases methylation	EXP		6480464	bisphenol A results in decreased methylation of RTL1 promoter	CTD	PMID:27312807
Rtl1	Mouse	bisphenol A	decreases expression	ISO	Rtl1 (Rattus norvegicus)	6480464	bisphenol A results in decreased expression of RTL1 mRNA	CTD	PMID:25181051
Rtl1	Mouse	chlorpyrifos	increases expression	EXP		6480464	Chlorpyrifos results in increased expression of RTL1 mRNA	CTD	PMID:37019170
Rtl1	Mouse	ethylparaben	decreases expression	ISO	RTL1 (Homo sapiens)	6480464	ethyl-p-hydroxybenzoate results in decreased expression of RTL1 mRNA	CTD	PMID:37690743
Rtl1	Mouse	mercaptopurine	decreases expression	ISO	Rtl1 (Rattus norvegicus)	6480464	Mercaptopurine results in decreased expression of RTL1 mRNA	CTD	PMID:23358152
Rtl1	Mouse	paraquat	decreases expression	ISO	Rtl1 (Rattus norvegicus)	6480464	Paraquat results in decreased expression of RTL1 mRNA	CTD	PMID:32680482
Rtl1	Mouse	phenobarbital	increases expression	EXP		6480464	Phenobarbital results in increased expression of RTL1 mRNA and Phenobarbital results in increased expression of RTL1 mRNA alternative form	CTD	PMID:23091169 and PMID:28541575
Rtl1	Mouse	phenobarbital	increases expression	ISO	RTL1 (Homo sapiens)	6480464	Phenobarbital results in increased expression of RTL1 mRNA alternative form	CTD	PMID:28541575
Rtl1	Mouse	purine-6-thiol	decreases expression	ISO	Rtl1 (Rattus norvegicus)	6480464	Mercaptopurine results in decreased expression of RTL1 mRNA	CTD	PMID:23358152
Rtl1	Mouse	valproic acid	increases methylation	ISO	RTL1 (Homo sapiens)	6480464	Valproic Acid results in increased methylation of RTL1 gene	CTD	PMID:29154799

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rtl1	Mouse	angiogenesis	acts_upstream_of_or_within	IMP	MGI:3776873	2290270	PMID:28111885	MGI	PMID:28111885
Rtl1	Mouse	embryonic placenta development	acts_upstream_of_or_within	IMP		2290270	PMID:26138477	MGI	PMID:26138477
Rtl1	Mouse	embryonic placenta development	acts_upstream_of_or_within	IMP	MGI:3776873	2290270	PMID:28111885	MGI	PMID:28111885
Rtl1	Mouse	gene expression	involved_in	IMP	MGI:3776873	2290270	PMID:32878913	MGI	PMID:32878913
Rtl1	Mouse	labyrinthine layer development	acts_upstream_of_or_within	IMP	MGI:3776873	2290270	PMID:28111885	MGI	PMID:28111885
Rtl1	Mouse	labyrinthine layer development	acts_upstream_of_or_within	IMP		2290270	PMID:26138477	MGI	PMID:26138477
Rtl1	Mouse	placenta development	involved_in	IDA		2290270	PMID:32878913	MGI	PMID:32878913
Rtl1	Mouse	placenta development	involved_in	IMP	MGI:3776873	2290270	PMID:32878913	MGI	PMID:32878913
Rtl1	Mouse	skeletal muscle satellite cell proliferation	involved_in	IMP	MGI:3776873	2290270	PMID:32878913	MGI	PMID:32878913
Rtl1	Mouse	skeletal muscle satellite cell proliferation	acts_upstream_of_or_within	IMP	MGI:3776873	2290270	PMID:32878913	MGI	PMID:32878913
Rtl1	Mouse	skeletal muscle tissue development	involved_in	IMP	MGI:3776873	2290270	PMID:32878913	MGI	PMID:32878913
Rtl1	Mouse	skeletal muscle tissue development	involved_in	IDA		2290270	PMID:32878913	MGI	PMID:32878913
Rtl1	Mouse	skeletal muscle tissue development	acts_upstream_of_or_within	IMP	MGI:3776873	2290270	PMID:32878913	MGI	PMID:32878913

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rtl1	Mouse	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	2290270		UniProt	GO_REF:0000044
Rtl1	Mouse	Z disc	is_active_in	IDA		2290270	PMID:32878913	MGI	PMID:32878913
Rtl1	Mouse	Z disc	located_in	IDA		2290270	PMID:32878913	MGI	PMID:32878913

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rtl1	Mouse	molecular_function	enables	ND		2290270		MGI	GO_REF:0000015

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Rtl1	Mouse	abnormal basement membrane morphology		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	abnormal placenta development		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	abnormal placenta labyrinth morphology		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	abnormal placenta size		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	abnormal trophoblast layer morphology		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	decreased placenta weight		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	decreased survivor rate		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	enlarged placenta		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	fetal growth retardation		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	impaired placental function		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	increased placenta weight		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	lethality throughout fetal growth and development, incomplete penetrance		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	neonatal lethality, complete penetrance		IAGP		5509061		MGI	PMID:18176565
Rtl1	Mouse	neonatal lethality, incomplete penetrance		IAGP		5509061		MGI	PMID:18176565

#	Reference Title	Reference Citation
1.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:8889548	PMID:12796779	PMID:12937418	PMID:15716091	PMID:16093683	PMID:16309881	PMID:16575173	PMID:16575184	PMID:16602821	PMID:17216273	PMID:17901046	PMID:18176565
PMID:18854139	PMID:19126398	PMID:19194500	PMID:19264764	PMID:19762426	PMID:20610486	PMID:22326222	PMID:23085235	PMID:23139813	PMID:23195472	PMID:26138477	PMID:26487685
PMID:27904015	PMID:28111885	PMID:28378742	PMID:28934383	PMID:29931170	PMID:31301299	PMID:31686651	PMID:31882978	PMID:32878913	PMID:33484574	PMID:35513363	PMID:35567414
PMID:37372444	PMID:38521877	PMID:39382697

Rtl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	109,531,141 - 109,570,852 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	109,555,627 - 109,566,764 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	109,564,900 - 109,604,418 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	109,589,193 - 109,600,330 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	110,828,379 - 110,833,613 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	110,037,976 - 110,043,210 (-)	NCBI		MGSCv36	mm8
Celera	12	110,784,688 - 110,790,104 (-)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	60.38	NCBI

RTL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	100,879,753 - 100,903,722 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	100,879,753 - 100,903,722 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	101,346,090 - 101,370,059 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	100,416,802 - 100,420,878 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	81,400,811 - 81,405,006 (-)	NCBI		Celera
Cytogenetic Map	14	q32.2-q32.31	NCBI
HuRef	14	81,528,723 - 81,532,918 (-)	NCBI		HuRef
CHM1_1	14	101,285,181 - 101,289,375 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	95,115,189 - 95,139,155 (-)	NCBI		T2T-CHM13v2.0

Rtl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	134,325,231 - 134,335,780 (-)	NCBI		GRCr8
mRatBN7.2	6	128,543,904 - 128,549,384 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	128,543,939 - 128,549,182 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	6	133,710,207 - 133,721,191 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	133,711,154 - 133,716,847 (-)	NCBI	Rnor6.0		rn6	Rnor6.0
Cytogenetic Map	6	q32	NCBI

Rtl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955538	176,998 - 181,184 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955538	177,078 - 181,557 (-)	NCBI	ChiLan1.0	ChiLan1.0

RTL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	102,031,676 - 102,058,137 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	101,246,821 - 101,262,055 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	81,498,463 - 81,529,551 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	100,811,749 - 100,816,359 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	100,812,227 - 100,816,306 (-)	Ensembl	panpan1.1		panPan2

RTL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	69,102,081 - 69,126,209 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	69,102,644 - 69,106,687 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	68,619,982 - 68,646,853 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	69,385,732 - 69,412,597 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	69,386,134 - 69,390,177 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	69,047,435 - 69,074,288 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	69,113,293 - 69,140,165 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	69,511,471 - 69,534,272 (-)	NCBI		UU_Cfam_GSD_1.0

Rtl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	5,411,964 - 5,434,210 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936604	4,648,928 - 4,655,418 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RTL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	121,707,122 - 121,711,414 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	121,706,955 - 121,720,472 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	132,097,039 - 132,100,222 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RTL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	78,840,599 - 78,865,282 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	78,842,440 - 78,846,519 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	65,999,877 - 66,028,159 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rtl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624734	3,219,270 - 3,227,154 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Rtl1
197 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	355
Count of miRNA genes:	277
Interacting mature miRNAs:	297
Transcripts:	ENSMUST00000149046
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
39128213	Lwq23_m	liver weight QTL 10 (mouse)					12	80956708	113383533	Mouse
1300883	Ath21_m	atherosclerosis 21 (mouse)			Not determined		12	85961579	119961683	Mouse
12910532	Nrq10a_m	noise-induced hearing loss resistant QTL 10a (mouse)					12	92750025	120092757	Mouse
12910533	Nrq10_m	noise-induced hearing loss resistant QTL 10 (mouse)					12	92750025	120092757	Mouse
1357463	Vtbt14_m	vertebral trabecular bone trait 14 (mouse)			Not determined		12	92936097	120092757	Mouse
1301269	Sluc12_m	susceptibility to lung cancer 12 (mouse)			Not determined		12	96860337	120092757	Mouse
4142007	Chlq17_m	circulating hormone level QTL 17 (mouse)			Not determined		12	88052874	120092757	Mouse
4142002	Tbqt3_m	tibia bone quality traits 3 (mouse)			Not determined		12	35285496	109936243	Mouse
11039526	Ccc1_m	colitis susceptibility in the Collaborative Cross 1 (mouse)					12	93528334	111028223	Mouse
4141297	Plyid_m	Polymeric IgA dominance (mouse)			Not determined			109183385	115885122	Mouse
1300545	Lifespan3_m	life span 3 (mouse)			Not determined		12	88052874	120092757	Mouse
4141610	Tailaq1_m	tail length adjusted QTL 1 (mouse)			Not determined			80956708	113383533	Mouse
1301836	Heal5_m	wound healing/regeneration 5 (mouse)			Not determined		12	89939031	120092757	Mouse
13524846	Ppiq11_m	prepulse inhibition QTL 11 (mouse)					12	82666396	116666396	Mouse
10412156	Nociq3_m	nociceptive sensitivity inflammatory QTL 3 (mouse)			Not determined		12	86396075	114831653	Mouse
13524842	Ppiq10a_m	prepulse inhibition QTL 10a (mouse)					12	77512220	111512220	Mouse
1301879	Insq10_m	insulin QTL 10 (mouse)			Not determined		12	83532075	117532224	Mouse
10402491	Dipa4_m	drug induced psychomotor activation 4 (mouse)			Not determined		12	91222515	120092757	Mouse
1301492	Dbsty3_m	diabesity 3 (mouse)			Not determined		12	83532075	117532224	Mouse
4141335	W6q10_m	weight 6 weeks QTL 10 (mouse)			Not determined			80956708	113383533	Mouse
5491194	Mobq3_m	multigenic obesity QTL 3 (mouse)			Not determined		12	89664071	120092757	Mouse
1302138	Im6_m	immunoregulatory 6 (mouse)			Not determined		12	96860337	120092757	Mouse
1301308	Prdt4_m	prion disease incubation time 4 (mouse)			Not determined		12	88308354	120092757	Mouse
1301922	Bbaa6_m	B.burgdorferi-associated arthritis 6 (mouse)			Not determined		12	90308268	120092757	Mouse
1302177	Dps2_m	delta power in slow-wave sleep 2 (mouse)			Not determined		12	94146064	120092757	Mouse
10412075	Nils1_m	neointima lesion size 1 (mouse)			Not determined		12	102024665	120092757	Mouse
27226793	Feml10_m	femur length 10, 5 week (mouse)					12	68346774	113363620	Mouse
4142401	Egq10_m	early growth QTL 10 (mouse)			Not determined			80956708	113383533	Mouse
1300973	Abmm_m	antibody mediated myocarditis (mouse)			Not determined		12	93264461	120092757	Mouse
13524849	Ppiq11a_m	prepulse inhibition QTL 11a (mouse)					12	80989143	114989143	Mouse

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	NM_184109	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_030246797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC152063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BK001261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU434913	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU434918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000149046 ⟹ ENSMUSP00000115957

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	12	109,555,627 - 109,566,764 (-)	Ensembl
GRCm38.p6 Ensembl	12	109,589,193 - 109,600,330 (-)	Ensembl

RefSeq Acc Id:

NM_184109 ⟹ NP_908998

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	12	109,555,627 - 109,566,764 (-)	NCBI
GRCm38	12	109,589,193 - 109,600,330 (-)	NCBI
MGSCv37	12	110,828,379 - 110,833,613 (-)	RGD
Celera	12	110,784,688 - 110,790,104 (-)	RGD
cM Map	12		ENTREZGENE

Sequence:

show sequence

GCTCAGAGGCAATCAAGGAGCTAACGTGACCAAGTCTCGCTCTCGGGCAGGCGCTAACAGTGGTTTTGGTCTCCACAGTTGCGGTCTCTGACCACACACATCACAATCTTACCAGTCTTCAGAGCACA
CTCCTTTCCAACCGACGACATGATAGAACCCTCTGAAGACTCATTTGAGACGATGATGGAGCTTAAGAATCCATCATCAAAACAAATGGAGTCCTCCGAGGGCTCATCCAACACCGTTGAAGAGACAC
CAGGCAGCAGTGGAGCCCAGGCGGGGGCCCAGGCAGGGGCCCAGGCGGAGGCCCAGGCGGAGACCCAGGTGGAGGCCCAGGCGGAGGCTCAGGCTGAAGCCCAGGTTGAGGCCCAGGTTGAGGCCCAG
GCGGGCTCAGATAGTGGCCCAGCCCAGGAAGAAAAGGAGCCACCCAGTGGCCCCCTCAAGGAAATGCAAGAGCTGCCCACTAATCTACTCCAAGAAGTGGAGGAGCCATCCAGTGGCCCCCACCAGGA
AATGCAAGAGCTGCCCACTGATCTACTCCAAGAAGTGGAGGAGCCATCCAGTGGCCCCCACCAGGAAATGCAAGAGCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGTGGCCCCTACC
AGGAAATGCAAGAGCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGTGGCCCCTACCAGGAAATGCAAGAGCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGTGGCCCC
TACCAGGAAATGCAAGAGCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGTGGCCCCTACCAGGAAATGCAAGAGCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGCGA
CCCCTGTGAGGCATCATCTAACGATCTACCCCAAGACATGGAGGAATCAAGTGATGATGGTTCGAACCAGGAGTCGAGTGATGGTTCAAACCACGAATTAAGTAATGGTTCAAACCATGAGTCGAGCT
TTGGTTCAAACCCAGAGTCGAGCGATGTTTCCAACCTGGAGTCAAGCGGTGGTTCAAACCAGGAGTCCAGCGATGGTTCACAAAAGGAGTCAAGCTATGATTCAAACCCGGAGTTAAGTGATAATTCA
AACCAGGAGTTAAGCGATAATTCGAACCAGGAGTCAAGCGACAGTTCAAACCAGTCAAGTGATATTTCAAACCAGGAAGGGTCGGAACCACTCAGTGAGGCATCCGATTATAGCATGGATGAAACAAT
CAACTCATCCGAGACCCAGTCAGACCAAGATGATACTGACCTGGGAGATGACGAGGAAGAGGAGGAAGAGGAAGGTGGTGAAGAGGAAGGTCAGCCCAAGAACTCTCCAGAAGAAGTCGTGGCCACCA
TGGGGAACGTCATCTCGCTGTTCCTCCGGATGCAAGACCTAAAAGAACAACAGAGAGTGGCAGAAAGGCTCATGATGCAGGCTATCAACGAAGGTCGCCTGCCCTCCCTCAGGCCCTTCTCTGGAGAT
CGCAGAGACTACCATGAGTTTGTCGTGCTCTGCCAGATGACAATGCAGAACTACCCAAGTATGCTATACAATGATGAGCTGCGGGTGAAATTCGTCATCCGCCACCTGACTGACCTAGCCTTGGAATG
GGCCAACGACCTCGTAGAGCAGAACAGCCCAGTGATAAACAACTTCTCAGCCTTCCTGGAGGCCATGTCAGAAAAGTTTGAGTATCGGCAGACCCTGCGTGTGGCGGAAGACGCCATGTTCAACATCA
GGCAGGGGAACCGCTGTGCGGCCGATTACATCAATGAGTTCCGGGGTCTGATACCCACCTTAGGCTGGCCAGATGAAGTCCTGCAGGCCCACCTGTGCCAGGGGCTCAACGAAGAGATCAGGCACTAT
CTGTTCCGGATCCCTCAGCCGAATTCCCTAGACAACCTGATTGTACTTGTCCTGCAACTTGAAGAAAAGCTGGCAGAGAGAAGAGCATTACTCAGGCTGCCACCTGAGTCGCGCCCAAGAAGCGTAGC
CTGGATGGATGCTCCCGCCCCAGAGAAGTGGAGGGTAAGCAGCTGGCTGCCCAATGAGTTCCACCCAGACATTGATCGCGATCACCTCTTCTTACTGCTCTTGGTGAGAGTGGACCCCTACCACAGTG
TCGCAGTGCGGGCCCTGGTGGACTCAGGAGCAGAAGGGAACTACATGGATGAGAGGTTTGCCCAGGAACACTATGTGGAACTCTATGAGAAGCCTTATCCACAGATAATCCAAGGTGTGGATGGCATC
CCAATTGGCAATGAACCCGTCTGGCTGTGCACCGAGCCCCTGGTATGTGTCCACCAGAAGCATTATGAGTACATCGAATTTGACATCTTACCTTCGCCCAACTTCTCCATCGTCTTAGGCATGAAGTG
GCTCCGAACCCATGCCCCTGAAGTCGACTGGATGAGAGGCCGGTGTACCTTCCACTCTCCCTACTGTCTGCGGAATTGCTTCACCCCACCTCCACCATGCATCGCACTAGAGACATACAGCATAAGCC
TACTGCCCGGATTGCCACACACATACTCAGACCTGGCCGACGTGTTTAACCCGAGGGAGGCAGATGATGAGACTTCCGACCAGCCAAGCTCAGACGGATCCGATGATCTTTCTGAATCAGAGCCCTCT
GAGCTTCAGCAGGCTGGAGACAGTGATCAAAGCGGCGTCTTTTACGAGTCTGGGGCCCGAGAGACTTTGGAACCTGTGAGCGCCAGGATGCAAGAGAAAGCCAGGCAGCAAGAGAAAGCCAGGGAGCA
AGAGGAATACTGGATACTGTATGACATGCTGACTGACAGACAAGACTACACGCAGATGGTACCAGAGCTATTCGACCAGCTACATGGAGCGGCATGGTTCACAAAACTGGAGCTGCTTGGGATTAAGG
AAAGTGAGATGAGGCACACGGTCACACACACGGAAGACACTTGGAGAGCATCGTTCGGTTTCGGCCTTCACCAGATGAGATGCTACCGGCCCTTCACAATGAACTCATACTCTGACGAAGGGAACAAC
ATTGTTCACTTCATCCTAAAAGACATCCTAGGGTTGTTTGTGATTTGCCATGGCAGAGAGGTCCTGGTCTACTCAATGAGCCAGGAGGAACACTCCCAGCATGTCCGCCAAGTCCTGGTCCGCTTTCG
GTATCACAACATCTACTGTTCACTGGACAAAACTCAGTTCCATCGCCAGACCGCTGAAATCTTGGGCTTCAACATATCCCCCAAAGGGGTGAAACTGAACAAGAACCTTATGAACCTCATCGTGGGGT
GCCCTGTCCCTGGCAGCAGGAGGTGTCTTCAAAGTGTGATTGACCTTGTCTATCCCTATCGCCACTTCGTGGAGAACTTCGCTGTCATCGCAGCACCCCTAGTGAGACAACTGCTGAGTTCAGAGCCC
TACTACTGGGGAGAAGAGGAGCAGGAGGCCTTGGAATCCCTGAAGAGGGCTTTCCGCAAGTCGCCCGTTCTCTATCACCCTAAGCCTCAGAACCCATTCTACTTGGAAACAGACATCACTGGGTCATT
CCTGTCTGCCTCCCTGGTCCAAACCGACGACGAAACTGGCAAGAAATCTACCTGTGCTTTCTATTCAAGACCCCTCTCTACAATGGAGGTGGAGTACCCTCGAGTGGAGATGAGGATCCTTCCAATCC
GGGCTGCCTTCATGGTGTGGTGCCGCTACCTGGAGAACACCGAGGAGCCCATCATGATCCTTCTCAACACAGAGGATCTAGCCTCTCTGAATAATGACAGGCTCACCGTACTTCTCCCCGGGCATTGG
GTCTTCTTCTTCTCACACTTCAATTTTGGTGTTATGGAGATGCCAGCTGAAGGTGACACACAAGCACTCTTCCGCAGATGTTGGAACCAGAGAGGCTTCAGAGCAAGGTTTCTGCGCCCACTGCTGCT
TATGTCCATTAGGGCAAATCTAAGGTACTTTGACAGATCCTCTGAGACTGAGGATAAAGAGGATGATGAAGAAGAGGAGGAGGAAGATGGTGAAGAAGAAGAAGGGGAGGAGGAGGAAGATGGTGAAG
AAGAAGAAGGGGAGGAGGAGGAAGATGGTGAAGAAGAAGAGGAGGAGGAGGAAGATGATGAAGAAGAAGAAGGGGAGGAGGAGGAAGATGGTGAAGAAGAAGAAGGGGAGGAGGAGGAAGATGGTGAA
GAAGAAGAAGGGGAGGAGGAGGAAGATGGTGAAGAAGAAGAAGGGGAGGAGGAGGGAGAGGAGGAGGAAGAAGGAGAGGAGGAAGAGGAGGAAGAAGAGGATGAGGAGGAAGAGGAGGAGGAAGAGGA
AGAGGAGGAAGAAGAGGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAAGAAGAGGAGGAGGAAGATGAGGAAGAAGAGGATGAGGAGGAAGAAGATGAGGAGGTGCCCAGCATGGTGCGGGAGCTAC
TGGCTGCCATCCCGATGGACCATATCCTCAATGGCTTACTGGCTCACTTCAGTGTGGCCCAGATCCGGGCCGTTGTCCTAAACTTCTTCCGTGGCCTGCTCTACTGGAAGAGTCTCCTGGGTGTGGCA
GCTGTCCTGGTGATGTTGAGAGCAAGGCAGCCCCTCTCCCCAGTGCCTGCCCCTAATTTGGAAGTGGCCAGGCCTCAGCACCGGCACACACTCCGACTCATCCTGGACTCGACCCTCATTGCGAGTAG
TGGCATGGCCACAGCCATCGCTCAGTTGCTCAGCCAGATGCCCCCTCTAGTGGGTGCCAACACCCTCCCAGCTCGAGAGCTGGCTGAGCTTTTCCTGGGCCCAAGGTGCTGGCATCGGAATGCTCTGC
ATTCCCAGCCTCCACGGGGGATGCGCTTCACCCCTGGGTTCTGGTTGACCCTGTGTGAGTTCTTTGGGGTCAGAGTCAACCCTGAGGATGACGTCTTTCCTGACCCTTACCAGCACCGGTACTTGGAA
CTGCACGTCGTTGGGGATGAAGATGTCGTCTTGCGAGAAGCCCTGCAAGACGACCTGCAACGTTACCGTCAGTGTGGCCTGCATGACGGCCTGCAAGACACCTCGCAGGACGCGCAGGACAACGACGT
GCAAGAGGACCTGTTTGGCGACCAGGAAGCGGTCACCTTCAGACCACGAAATCTTTTGGACCCAGAGGTCCTAGATTTCCTCAACAACCGGCTACTCTACACCCTGGGCACCGATGGCCGCCTTACTC
TGCTTAGCAGAGATCAGGTGGCCCAGGCCCTCACACGATTCCTGGCCATGGCCTCCAGAATGGCGCTGCCTTCCCCAGCCAGGGAACAGGCAAGGCTAGAAGAGCTATCAGACTCAGATGATGAACTT
GACTGAAAACACACCAAGTCACTGTCATTTTCCCTTGTGCCTCGGCCAGCTTCGCTCAGATCCAGCACACCCTCTTGCTACTCCTAACCCAAGGGGAACCCACTTGTGAAGGGCCACAACTTCATCAA
CCAGCAACATCATCTGTGCTAAAGAACTAGCCAACTATCAGCGTCCCAGAACCAGCCAAGACTGTGTAACCCTAACTGTCCTAACTGTCCGGGCCCCAGGCCCACAAAAGGGAGTGAGACCAATGAGG
AGAGAGCAGTGATGAGCAACAGTGACCCCGTCACCCCAGGCCAGATGCAGAGCAGATACAGCAGGTGCAGCCAAGCAAGCAGATGCCAGTGACCCCACCACCACCCCCTGAGTGGCAGGCGGCCACCT
GTGCATCCTGGGACACTGACCTTGGGTGCTCCACGGACTTCTACCTCTACACCGGTGCTCCGACTCCCCTGGACACGCCCCTACTCCCTCCCAGTCTCCCAAGGTGCTGTGGTTCCATGCTTTCCACA
ACCCCAGCCCACCCTGCAAGCAAGTCCACCCCCCCCCCCACAACCCACCCACCCACTACCGGTCTGGTCCGGCTCCATTGACACCTCATCTGACCCTGAACTCTGATCTTACCTGGGCAGAACTGCTC
CAAGGAGCATTCGACGTACCAGTGTGACTTACCAGATGGACTGATCCACCCTGAAGGTCCCTGAGACTCAGAGGACCCAAGAAAGGGTGGTAGCAACCAAGTGGGGCTCCCTTTTCCCTCCCCAAATG
GACATATGGACAGTGCAGGGGACAGAGACCTTCCATAAAGGAGGGAGCCCCCAAGAGACACTGGTGAAGCCCCAGATACCCAGAGTACTGTGCCAAGGAGCCAAGAGTGCTCTGACCAGACCCACTGC
TCACTGCCACAGGAAGGAGAGGTCCTTCCATTGCTTTCCCAACTCATACCTGCTTTTGCCCCATGAATAAAGAGAAGAAAAGATTA

hide sequence

RefSeq Acc Id:

XM_030246797 ⟹ XP_030102657

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	12	109,531,141 - 109,570,852 (-)	NCBI
GRCm38	12	109,564,900 - 109,604,418 (-)	NCBI

Sequence:

show sequence

CAAACAGCCACCTTTGCAAGGGGCAAGGACTCTCCCTCTCCACCAGCTTCTAAGGAAGAGGCAGGAACCGAGCAGGACCATCGGAGATCCACTTGGACACTTGAAGCCAAGGTTTTGGTCTCCACAGT
TGCGGTCTCTGACCACACACATCACAATCTTACCAGTCTTCAGAGCACACTCCTTTCCAACCGACGACATGATAGAACCCTCTGAAGACTCATTTGAGACGATGATGGAGCTTAAGAATCCATCATCA
AAACAAATGGAGTCCTCCGAGGGCTCATCCAACACCGTTGAAGAGACACCAGGCAGCAGTGGAGCCCAGGCGGGGGCCCAGGCAGGGGCCCAGGCGGAGGCCCAGGCGGAGACCCAGGTGGAGGCCCA
GGCGGAGGCTCAGGCTGAAGCCCAGGTTGAGGCCCAGGTTGAGGCCCAGGCGGGCTCAGATAGTGGCCCAGCCCAGGAAGAAAAGGAGCCACCCAGTGGCCCCCTCAAGGAAATGCAAGAGCTGCCCA
CTAATCTACTCCAAGAAGTGGAGGAGCCATCCAGTGGCCCCCACCAGGAAATGCAAGAGCTGCCCACTGATCTACTCCAAGAAGTGGAGGAGCCATCCAGTGGCCCCCACCAGGAAATGCAAGAGCTA
CCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGTGGCCCCTACCAGGAAATGCAAGAGCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGTGGCCCCTACCAGGAAATGCAAGA
GCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGTGGCCCCTACCAGGAAATGCAAGAGCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGTGGCCCCTACCAGGAAATGC
AAGAGCTACCCACTGATCTACTCCGGGAAGTGGAGGAGCCATCCAGCGACCCCTGTGAGGCATCATCTAACGATCTACCCCAAGACATGGAGGAATCAAGTGATGATGGTTCGAACCAGGAGTCGAGT
GATGGTTCAAACCACGAATTAAGTAATGGTTCAAACCATGAGTCGAGCTTTGGTTCAAACCCAGAGTCGAGCGATGTTTCCAACCTGGAGTCAAGCGGTGGTTCAAACCAGGAGTCCAGCGATGGTTC
ACAAAAGGAGTCAAGCTATGATTCAAACCCGGAGTTAAGTGATAATTCAAACCAGGAGTTAAGCGATAATTCGAACCAGGAGTCAAGCGACAGTTCAAACCAGTCAAGTGATATTTCAAACCAGGAAG
GGTCGGAACCACTCAGTGAGGCATCCGATTATAGCATGGATGAAACAATCAACTCATCCGAGACCCAGTCAGACCAAGATGATACTGACCTGGGAGATGACGAGGAAGAGGAGGAAGAGGAAGGTGGT
GAAGAGGAAGGTCAGCCCAAGAACTCTCCAGAAGAAGTCGTGGCCACCATGGGGAACGTCATCTCGCTGTTCCTCCGGATGCAAGACCTAAAAGAACAACAGAGAGTGGCAGAAAGGCTCATGATGCA
GGCTATCAACGAAGGTCGCCTGCCCTCCCTCAGGCCCTTCTCTGGAGATCGCAGAGACTACCATGAGTTTGTCGTGCTCTGCCAGATGACAATGCAGAACTACCCAAGTATGCTATACAATGATGAGC
TGCGGGTGAAATTCGTCATCCGCCACCTGACTGACCTAGCCTTGGAATGGGCCAACGACCTCGTAGAGCAGAACAGCCCAGTGATAAACAACTTCTCAGCCTTCCTGGAGGCCATGTCAGAAAAGTTT
GAGTATCGGCAGACCCTGCGTGTGGCGGAAGACGCCATGTTCAACATCAGGCAGGGGAACCGCTGTGCGGCCGATTACATCAATGAGTTCCGGGGTCTGATACCCACCTTAGGCTGGCCAGATGAAGT
CCTGCAGGCCCACCTGTGCCAGGGGCTCAACGAAGAGATCAGGCACTATCTGTTCCGGATCCCTCAGCCGAATTCCCTAGACAACCTGATTGTACTTGTCCTGCAACTTGAAGAAAAGCTGGCAGAGA
GAAGAGCATTACTCAGGCTGCCACCTGAGTCGCGCCCAAGAAGCGTAGCCTGGATGGATGCTCCCGCCCCAGAGAAGTGGAGGGTAAGCAGCTGGCTGCCCAATGAGTTCCACCCAGACATTGATCGC
GATCACCTCTTCTTACTGCTCTTGGTGAGAGTGGACCCCTACCACAGTGTCGCAGTGCGGGCCCTGGTGGACTCAGGAGCAGAAGGGAACTACATGGATGAGAGGTTTGCCCAGGAACACTATGTGGA
ACTCTATGAGAAGCCTTATCCACAGATAATCCAAGGTGTGGATGGCATCCCAATTGGCAATGAACCCGTCTGGCTGTGCACCGAGCCCCTGGTATGTGTCCACCAGAAGCATTATGAGTACATCGAAT
TTGACATCTTACCTTCGCCCAACTTCTCCATCGTCTTAGGCATGAAGTGGCTCCGAACCCATGCCCCTGAAGTCGACTGGATGAGAGGCCGGTGTACCTTCCACTCTCCCTACTGTCTGCGGAATTGC
TTCACCCCACCTCCACCATGCATCGCACTAGAGACATACAGCATAAGCCTACTGCCCGGATTGCCACACACATACTCAGACCTGGCCGACGTGTTTAACCCGAGGGAGGCAGATGATGAGACTTCCGA
CCAGCCAAGCTCAGACGGATCCGATGATCTTTCTGAATCAGAGCCCTCTGAGCTTCAGCAGGCTGGAGACAGTGATCAAAGCGGCGTCTTTTACGAGTCTGGGGCCCGAGAGACTTTGGAACCTGTGA
GCGCCAGGATGCAAGAGAAAGCCAGGCAGCAAGAGAAAGCCAGGGAGCAAGAGGAATACTGGATACTGTATGACATGCTGACTGACAGACAAGACTACACGCAGATGGTACCAGAGCTATTCGACCAG
CTACATGGAGCGGCATGGTTCACAAAACTGGAGCTGCTTGGGATTAAGGAAAGTGAGATGAGGCACACGGTCACACACACGGAAGACACTTGGAGAGCATCGTTCGGTTTCGGCCTTCACCAGATGAG
ATGCTACCGGCCCTTCACAATGAACTCATACTCTGACGAAGGGAACAACATTGTTCACTTCATCCTAAAAGACATCCTAGGGTTGTTTGTGATTTGCCATGGCAGAGAGGTCCTGGTCTACTCAATGA
GCCAGGAGGAACACTCCCAGCATGTCCGCCAAGTCCTGGTCCGCTTTCGGTATCACAACATCTACTGTTCACTGGACAAAACTCAGTTCCATCGCCAGACCGCTGAAATCTTGGGCTTCAACATATCC
CCCAAAGGGGTGAAACTGAACAAGAACCTTATGAACCTCATCGTGGGGTGCCCTGTCCCTGGCAGCAGGAGGTGTCTTCAAAGTGTGATTGACCTTGTCTATCCCTATCGCCACTTCGTGGAGAACTT
CGCTGTCATCGCAGCACCCCTAGTGAGACAACTGCTGAGTTCAGAGCCCTACTACTGGGGAGAAGAGGAGCAGGAGGCCTTGGAATCCCTGAAGAGGGCTTTCCGCAAGTCGCCCGTTCTCTATCACC
CTAAGCCTCAGAACCCATTCTACTTGGAAACAGACATCACTGGGTCATTCCTGTCTGCCTCCCTGGTCCAAACCGACGACGAAACTGGCAAGAAATCTACCTGTGCTTTCTATTCAAGACCCCTCTCT
ACAATGGAGGTGGAGTACCCTCGAGTGGAGATGAGGATCCTTCCAATCCGGGCTGCCTTCATGGTGTGGTGCCGCTACCTGGAGAACACCGAGGAGCCCATCATGATCCTTCTCAACACAGAGGATCT
AGCCTCTCTGAATAATGACAGGCTCACCGTACTTCTCCCCGGGCATTGGGTCTTCTTCTTCTCACACTTCAATTTTGGTGTTATGGAGATGCCAGCTGAAGGTGACACACAAGCACTCTTCCGCAGAT
GTTGGAACCAGAGAGGCTTCAGAGCAAGGTTTCTGCGCCCACTGCTGCTTATGTCCATTAGGGCAAATCTAAGGTACTTTGACAGATCCTCTGAGACTGAGGATAAAGAGGATGATGAAGAAGAGGAG
GAGGAAGATGGTGAAGAAGAAGAAGGGGAGGAGGAGGAAGATGGTGAAGAAGAAGAAGGGGAGGAGGAGGAAGATGGTGAAGAAGAAGAGGAGGAGGAGGAAGATGATGAAGAAGAAGAAGGGGAGGA
GGAGGAAGATGGTGAAGAAGAAGAAGGGGAGGAGGAGGAAGATGGTGAAGAAGAAGAAGGGGAGGAGGAGGAAGATGGTGAAGAAGAAGAAGGGGAGGAGGAGGGAGAGGAGGAGGAAGAAGGAGAGG
AGGAAGAGGAGGAAGAAGAGGATGAGGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGAAGAAGAGGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAAGAAGAGGAGGAGGAAGATGAGGAAGAAGAG
GATGAGGAGGAAGAAGATGAGGAGGTGCCCAGCATGGTGCGGGAGCTACTGGCTGCCATCCCGATGGACCATATCCTCAATGGCTTACTGGCTCACTTCAGTGTGGCCCAGATCCGGGCCGTTGTCCT
AAACTTCTTCCGTGGCCTGCTCTACTGGAAGAGTCTCCTGGGTGTGGCAGCTGTCCTGGTGATGTTGAGAGCAAGGCAGCCCCTCTCCCCAGTGCCTGCCCCTAATTTGGAAGTGGCCAGGCCTCAGC
ACCGGCACACACTCCGACTCATCCTGGACTCGACCCTCATTGCGAGTAGTGGCATGGCCACAGCCATCGCTCAGTTGCTCAGCCAGATGCCCCCTCTAGTGGGTGCCAACACCCTCCCAGCTCGAGAG
CTGGCTGAGCTTTTCCTGGGCCCAAGGTGCTGGCATCGGAATGCTCTGCATTCCCAGCCTCCACGGGGGATGCGCTTCACCCCTGGGTTCTGGTTGACCCTGTGTGAGTTCTTTGGGGTCAGAGTCAA
CCCTGAGGATGACGTCTTTCCTGACCCTTACCAGCACCGGTACTTGGAACTGCACGTCGTTGGGGATGAAGATGTCGTCTTGCGAGAAGCCCTGCAAGACGACCTGCAACGTTACCGTCAGTGTGGCC
TGCATGACGGCCTGCAAGACACCTCGCAGGACGCGCAGGACAACGACGTGCAAGAGGACCTGTTTGGCGACCAGGAAGCGGTCACCTTCAGACCACGAAATCTTTTGGACCCAGAGGTCCTAGATTTC
CTCAACAACCGGCTACTCTACACCCTGGGCACCGATGGCCGCCTTACTCTGCTTAGCAGAGATCAGGTGGCCCAGGCCCTCACACGATTCCTGGCCATGGCCTCCAGAATGGCGCTGCCTTCCCCAGC
CAGGGAACAGGCAAGGCTAGAAGAGCTATCAGACTCAGATGATGAACTTGACTGAAAACACACCAAGTCACTGTCATTTTCCCTTGTGCCTCGGCCAGCTTCGCTCAGATCCAGCACACCCTCTTGCT
ACTCCTAACCCAAGGGGAACCCACTTGTGAAGGGCCACAACTTCATCAACCAGCAACATCATCTGTGCTAAAGAACTAGCCAACTATCAGCGTCCCAGAACCAGCCAAGACTGTGTAACCCTAACTGT
CCTAACTGTCCGGGCCCCAGGCCCACAAAAGGGAGTGAGACCAATGAGGAGAGAGCAGTGATGAGCAACAGTGACCCCGTCACCCCAGGCCAGATGCAGAGCAGATACAGCAGGTGCAGCCAAGCAAG
CAGATGCCAGTGACCCCACCACCACCCCCTGAGTGGCAGGCGGCCACCTGTGCATCCTGGGACACTGACCTTGGGTGCTCCACGGACTTCTACCTCTACACCGGTGCTCCGACTCCCCTGGACACGCC
CCTACTCCCTCCCAGTCTCCCAAGGTGCTGTGGTTCCATGCTTTCCACAACCCCAGCCCACCCTGCAAGCAAGTCCACCCCCCCCCCCACAACCCACCCACCCACTACCGGTCTGGTCCGGCTCCATT
GACACCTCATCTGACCCTGAACTCTGATCTTACCTGGGCAGAACTGCTCCAAGGAGCATTCGACGTACCAGTGTGACTTACCAGATGGACTGATCCACCCTGAAGGTCCCTGAGACTCAGAGGACCCA
AGAAAGGGTGGTAGCAACCAAGTGGGGCTCCCTTTTCCCTCCCCAAATGGACATATGGACAGTGCAGGGGACAGAGACCTTCCATAAAGGAGGGAGCCCCCAAGAGACACTGGTGAAGCCCCAGATAC
CCAGAGTACTGTGCCAAGGAGCCAAGAGTGCTCTGACCAGACCCACTGCTCACTGCCACAGGAAGGAGAGGTCCTTCCATTGCTTTCCCAACTCATACCTGCTTTTGCCCCATGAATAAAGAGAAGAA
AAGATTATCTGACTTTGTGGTTTGTTCTAAAAGGGAGAGGGTGGATAGTAGGAGGCAGGACTGGAGAACATGGAGCATGGGGTCAGAAAGGATGGAGTGTGAAGAGAGGGTTGGGATGGGCAAGGGCA
AGGGTGGGAGGGGCAGGGATAGGAGGGCTTGACTCTCCAGAAACAGCTCATGAAGACATGGAGCAACAGGCCTCCTGTCTTCTCCTAAAGGGAGGGAAGTCAATTCACTCTCAAAACTTTGGGCTCCT
CTGGGAAATGGACCAAGGGTTTCATGGGGCAGAAGGAGGGTACCCAGAATTCCCAGCCCTCATCTGGTCCCAGCCCTCTAGTCACATGAGAAATGAGGAATGGCCAGACTGTGCTCAATGCCCACAGC
TGAGGAGGGTCAACAGGCAGGATGTTTGAGCTTGGATCCCAGAAAAACAGTTCTTAGAACCCAAGACTGCATCCCTCCACGCCCCCTCCAGCCTGCACTGGGGTCACTGTGCCCTTATGGGTCCTAAG
GGGCCTCATGACAAGGAATCTACCCCTGACCATAGCACCAGAAGATCATGGGGAGGATCCCAGGTTCAAGGTCAGGGGCTCAGCCTCACTCAGCACTTCCTCCTGTTGCTAAGGAGGCTCCAGTGGCC
CCCCACTGGAACCATTCCCACAGTTGGCCCCTGAGATCCTTGCCTTAAAAAAAGCTATCTTGAGGGATACTCTGGGATGGGGAAGGAGCTCCTAGGGGTAGAGGGAAATTGAGCAAATAGTCCCTTAC
TCACAAACTCTATACTTCCTACCCAGAAAATCTGCACACAAGCTAGGAGTATAAAAACAAGGGCCCCCTCCCACTGTGACCTCAAAGATAGTGGGCAGGTGCAATGAGCAGGGCCCTCACGCCCAAGG
GCCCTTTCTTAACTCTGCCCTTTATATCTTGCCTGGAAATGTACCCCTGAGTTAACCTCAAGGGGCCCTCTTTGGCCTGAGAATGTGTCAGACCCCTGGATACCCAGCATGACACCTCCCCCTACCTG
CTTTCAGCTCTTTGATCCCATCTATACAGGATCTATAAGCTTGGGTCCCAGAAAAACCCTACTTAGAACGCAAGATTGCATCCCTCCACGCCCCCTCCAGCCTGCACTGGGGTCACTGTGTCCTTATG
GGTCCTAAGGGGCCTCATGACAAGGAATCTACCCCTGACGGTAGCACCAGGAGATCATGGATAGGATCCCAGGTTCAAGGTCAGGGGCTCAGCCTCACTCAGCACTTCCTCCTGTTCCTAAGGAGCGT
CCATAACCTTAAGGTGGGACTGGGGTCCTATTGGAGGAGAACAAACGTACCAGTCCTGTACCCTCACTTAGTTTACCTGGGCACCTCCAACAAAACTGGGCCTCAAAACAAAACAAAACAATCCTGTC
CCTGCTTGGTGAGGACTTCTCTGGCCCAGTGAATGCAGAGATGACTTAGGTCAGGACTACTGCCAGGGGCCCCAAGGCCCTGAGGGCCCCAAGCAAGTGAGAGTGAAGGAGAACTCAGTGAGCCAGCA
GCCCGCCAAGAGGCTGCCAGTGATGTTGACTGCAGAGGTGCGTTTACCCACAGCCCGCACGAACACAGACCATAAAGGACAATAAAGGCCCGCAGGCCTACCAATCTACCCAGCAGGGATTTGTCCCC
ATTAACAGCAAAAGGAGGTGGTCCGGACTGTGAAGAGAGCTGGTGACGTGCTAAAACGTGCTAAAACGGTAGGTTATCAGGTTATCGGCGGAGCCACTTATAGAGATTGAAAAACACAACACAAACCT
TTTTTTTTCTCCTGGGGAAGAGAAAAGAAAAGAAAGAAATTGGTGTGAAAGTTCCTGCTAGGGGATGATAACATCACTTCCAACCCTGTCAAGGTGAAAACCAGAGGCCAGGCCCTGGCTGCAGACTC
CACCCACCAAGGAGCTGCCCCCACTTCCCAGCTTCAGTCCCCAACCAGAGAGCTCTGACAGCATCCAGGAACAAAGAGGAGCAGGGGCCCTCCCTTGCCCACCTTCCCTGTCCTCTCCATTGCTTCCC
CTTATAAGATGTCCCTGCAGGTACCAGAGCCAGTGACAGCACACACACAGGACCCTGAGTCCAGAGTTTTACCAGCTCCTCACCAGGCTGGAGCAGAGATCTCCACATGCCTGGGTAACCTGGGCTAA
CTTGGGCTACCCCCATAGTAAGAAAAGGAAAAGAAAATATTACCCACCCCTCAACTGTCCCATACACCTTAAGCCCTGGTGCTGGGCCCAGGGGACCACATCGTTAGACACGATCTGAGACCTGAGCA
GCAAACCTCATCTGGACTTTGATCCACCTGTGTGAGCTGAGAGACACGCATGACCATCTTGCCACCAAGACCGTGCAGGAGCACAAGTAGGAAGAAGGAGATTGGGGGCAGAGGGGGGGACAGGGAAG
GGAGAGACAGTGGTGAAGGGGAGGGGGACTGGGTGTGGCCTGGGTCCTCCCTGTCCTGCCCTCAAATCCTTTCACAGCTTCCAGGCTATTCACTCAGGGTGCTCCTGTGTGCCGGGGCTGGCTGCCAT
AGCTGGTAAATGCAGTTAATAATGGTGGTGTTGTGGGGATGGAGATGGGCCCTGTATGCATGCAATGACCTAGGTATTGGGGTTCAGACTCTACGCCAGCTGCTCATTGTGCTACTGAAGTGTCTGTG
GGCACCCGGCCTGGGAGGAGGATGAACAGGGATCTTCTGCACTCCTTAGGGGATCCAGAGTTTGAACTGAATGAGGTGAGACGTCTCCAGAAGGGCTCAAGGAGAGAGTAAGAGGCCGCCTGTAAGGG
ACCTCAGCCTCCTGGTCATAAAAACATAATCCTGGATAGAGGCAGAGGCCCCTCAAGGAGACCCTGTTCTGGGAGCACTGGTAATGCTCAGCCCTGCCCTGTCTCAGCCCTGTGCCCTGCTCTAGTAA
CAAAGACCCCATCTCTCAAGGATCCACCCTTTCTGCTAGGAGCTGGGTCCCCTCAGAGGACCTCCAGGAGAGAACGGCTCCTGGAATCCCAGTGGGAGGAGCCCCAGAGTAGGCCCAGGATCGACCTC
TGACCTGTCTACCCTTGGCCACAGAGTCAGAGGGTGACCCTTGGCCCAGCCCCAGGGAATGTCCCACCAGGGGTATAGCTCCCCCGCCAAGGAATGATCTCAGGTATGGCCCAGCCCCGGGTATTCCC
CTCCAGGAACTGTGGAGAATGGCGAGAAAGCATGCCAGGGGAAAAGAGCGAGCTGAAGACGCGTCCCTAAGCGGCCCAAGGTGCGCGGAGGAGGGTCCGGAGGCCTCACGCGGTTGAAGGGGGTGAAG
AAAGGCATCATATAGGAGCTGAATGGCTGTGCAATCAACTCCTGCATGACGCCGTTCCCACCCCCCAACTTCTCACTACACTGGGACCCTCCTCTCCTGAAAAAGCAAGGCAAGAAGCACAGACAACA
GGTAGGACAGACTCCCAGGGCTTAGTGTTAGAGGAAGGAAACCAAAGGCCAGCCAGCCCTAGGGCACCTGCAGCACAGTGGAAGCATCTACCCTCCTTGCCCAACCTCACTTCTTATAAACTCTCATG
GAGTGACTGGAGCCAATCCAGGGGATGAGGAGGGGGGAGAGGGAGCAGAGGGATGGGAGGGAGAGAGGAGGGGCAAGGGAGCACTGAAGGAGGGGTGGGGAAGCGGAGAGGGAAGGAAGGGTGACTGT
GGTCACAGGAGTGTCCTGCTAAGGTCCATCCCGAGTATCCAGTGGGTTCCTCTGCAGACCTAGAAGGGACTCATGGGAACCAGCAGGAGCTTAGACGCCCCAGATGGATCCCCCAAAAAGATGCATGG
GTTAAAAGCTACTCAGTGTGGTGAGGGGACAAACTGCAGGTACAGCTAACAACCGCTCCCCAGGTTCTTTGAGTGTCAACTTGAGTTACACTCCTCCATGAATAACTAAAAACCACAAACTGCTTTTG
CTTGCCTGTTAGTTTTTTTGTTTGTTTGTTTGTTTTTGAAACAGGATCTGTGTAATCCAGAGTGGATCCCGACTTCTCCATCTTCCTGCCTCAGGCTTCCAAGTGTGGCTATGATTGACAGGCCTCTG
TCACCATGGCCAGCTTGAATGGCACATGTGTATCACCTTACATATGAATAAAGTAAAAAAAAAAAATCTTTCCTGACTTGTGCTCTTCTCTTCCTTGTCTGGCACACCCACCAACTGCCAACAAACAC
TTGTCCCAGCATAGTCTCAGAGAGCAGGGTATAAAGAGGTAGTATGGGGGTGGGAGGGAGTAGTAAGGATGGGAGGCCAGAAGACAGGTGAACACAGGTGGGGAAGGGAGGACTCGGTGTTAAGCCAG
GGAGGAAGGGAGCTGCACACGACATGTGAATGACAAAGGGTTAAGGCAGCTCAATGCTGTGGTAAGATGCTGCAGATGTCAGTGGGGCAGGGGAGAGAGAGAAGGGGGGCTCAGGGCAGCATGTGGAA
CACAGCTGCACATCATCCAGGGCAGAAGAGGGTTGCAAAGGGACATGTATGTGTATGGGAGCATAGGGACATGGCTCACGGGAAGCAGGAGGGTCTCAGGGTGACGTATGTCACAAGGGAGAGATGAA
GGATATGATATCCCACGCAAAGAGGGGGTCTTCATGTCATAAAGAAAAGAACAGGGACATCCCATGATGCCTACCTACACAGGGGGGTGTCAGTAACATATGGAGAGATTAAGGGATTAAATCTAGCG
GATGGGGAGTGGTCCAAGGCTATACATGGGGGAGAGAATCCATGGTACAGGGGAGAAAAAATGTAAATGTGATGTGCAGAGGAGGGGTAACATGACACATAAAAAGAGGAGGGGCTCAGTATGACTCT
TGTACAGGAGAGCCTATGACTCCTGAGAAAGAGACTGGGCTGCATGTGGGACATAAGGAGGAGGGGCTCTGATAGAGGAAATAGGGGCTCGGTGTGACATCTGTCAAGGAAAGTGTTCATCACAAGTG
GGGAGAAGGACTAGATGTGACACCTATGAGTTGCTTTGTGACCTGGAGGACATGCACGTCACAGTGTGGTATGTGTAGAGGCAGAGCGCTCCATGTCACAAGGCAAGGGGTGGATGTCTCAACGTGCT
GCGTGCAGAGGTGGGGCTTCCCAACATGAAGAGAGAGCGAGAGGAGAAGAGTTCCGTGTACCGCATCTGGAGCACCAGCAGGGTTTGTGGTGACTAAAAGGAACGAGGGCTATGGGACACATGATTTA
GGGGCCCTCTCACGATGGAGGAGCTCAGAGTCAGGGAGGGGCCTAAGGTGAATGGGGAGTAAGTGGGATGAAGCTCGGGTGCACAGGGCACACGGGTGGGGCTAGGCTAAGCATGACACACGTGGGGA
GAGGTGTTCTCTCTCTAGGACACATGGGTAGAACTCAGGTGACCACGACAGGTGTGAGAGGGGGCATACAGAACGTAGGAAGGGTTAGGCTAAGCATGACACATGTAGAGGAATGGTGCTCTTCAGGA
CATATGGGTGGAGCTAGGCAAAGCGTGCCCCATTATGGAATTTTCTCTTTAAGACACATGGCTGACAATAGCCTAACCCTAACACAGGATGACAAGAGGAGAGGACTCAGTGTGAGGCCAGCAATAAG
ACATAAGAAATGTTAACACATGAACACAGAGGGTCTTGGAAGTGCAGCCTGATGGGAGGGGTCTGTCCAAGACAAAGCAGGTGTAGTGGGAAACCATGTAAAGATAGGGAAGAGAAACTTACTCTGAC
CCAGGTAGGGGAGTGGAGCTGAATGTGATACCCGTGGAGAGATGAGACGCAGTGTGACTCAGGACCCTTGTTGTGATTCATGGGTGGTGGGAGGGGCTCTGTGTGTGACATAGGTGTAGAAAGTTTTG
ACATGTAATGGGGTCTAGATGAGAAACACTTGGAAAAGAGACACAAATGTCTTGTGCGAGGGTAGAGAGCTCATAACTCTGAGTGCCACTGTTGAAAAGGGACTTAGCCTAACACAAAGGAGAATTGA
GGAACTGTGGGACACACGGCCAAGGAAAGACTTAGGATAGCACAGTGAGGACCAGTTTGATACCTAGGTGGCATGACCCCATGTGATGAACAGAAGGAGAACGGTTCTGTGAGAAAGGTGTGACAGGT
GACCGAGGGGAGTCTGTGTGAGAGGAAAGGGGTTCAGTGTGTCACAGGAAAAGAGCATGTGAGGCAGGAGTAGAGAGACACAAGGAGGCAAGACTCCAGGTGTCAGGAGAGGTGGATTGTGCTCATGG
TAAGAAGCATGGAGAATCTTTTCTGTTTGAGGCACATAGGCTGGAGCATGGTATGACAAATGGGGATGAGAGGTTCAAAGTGACACAGGGGAGGACACACAGGAAGGTAGTGCTTCATGTGGCACATG
GGTACAAAAGGGGCTCGGCATGACACACGCATGGGTGTGACACCTGGTGGCAGAGGGGGAATTGGTGTGAAACACAAAAGGGGAGGGGACTATGCAATTCACAAGCATGAGGTCAACATGACCCATGA
AGAGGAGAGGACCTCAAGAGAGCAAGAGGGCTGTGCTTTAGGTAAAACCAGAGGGGCAGGCGGGGTTCTACATGCCTGAAGAGCAAGGGTGAACACTGAGGGGAGGGGGGAGGGGGACTCAGTGTCAC
AGGGGAGGGTAACAGACTTGGTCTAGCACACAAATTGAGAAGTCCATGACTCAGTGGCTGTGTAAGTGAGGAGAGAGACTCCAGGTGACAGGGGTGGAGGCAGGATTCAATGTCACTTAGGTGTGGGG
GCTATGGATGATACATCCCAGCGGTGGGCGTTTGGTGTGACACACAGGGGCTTGTGTGACACATGAATGGAGGAACTTTGTGTGACACGTGTTTCTTACTGACAGGGAGGTGGGAGAAACTCTGCACT
TGGCCTGGCAGGAGTTTGCATTAGTAGCACAGAGAGGAGTGGCTACCTAAAACGTGGGAGAGGGTGGTGTGTGGGCGAAGGAAGAGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGACACATGAGGA
GACAGGGCAGAGCTCAGATAAGGGACAGCTGCATGAGCCTAGGTGGGACACTAAGGAGGAGAGTGGGCTTGGTGTGACATTAGTAGACTCAGCCTGAAGCACTGAAACAACACAAGATACAGAAGATA
CCAGCTTTTACTGAACTACTTGTGTGGTCACTGTGGGGAGAGCTTTGTGTGACTTCTGGATGCAGGAGGATGTCTATGTGACAGTCCAGTGTGGAGCAACTTGGGGTGACATGGAGGTGGGGCAGGGA
CTAAAGGGGTAGGGGAGGAGTTCGAGGTGATATCAAAAGAGGAGGTGGGTCCATGTCACATACAGTAGGGTCACAGATTGTGACACATGACTAGATAGAGATTTATAGGTTAGTAAATGGCTCTGTGT
GATACTAGAATAGAAGCATAGTTCAATGTGACCCAGGAATGAGGGCAGAGGACCCAAGTAATAATTCGGTGGAGGGGTACTTAGTAGGACATAAAAGGGGGACTTTGTTATGGCATTGGAAGACGAGA
TAGTCAGGACACATTAGACTCAATTTAGGTTGGGGGTTCATATGATAACTGGAGGGGAGTTCATGAGACACAGAGTGGAAAAGGGGTCAGGATAGGACACACCTGAAAGAGGGGTTTGGTCAAGTACC
CCGTACTGTGTCTCAGGTAAAGGAAGAAGACACAGTAGCCAGGAGGGCGGTCTGACAAGAGTGAGAGAACCTCAGGAGGCTCAGTTCACACGTGGAGGCAGCTTGGCATGAGTCACAGAGGGATTCGG
TGTGATGAAAGGGTAGATAGAGAGGGATTCATTGTGGTAGGAGGAAGCCTGTGATCTGTGACCAGATATCGGACCTAGTGTAACACAGAGGTGACAGAGGTTAAGTGTGACAATGAGAGCCTGAACAT
CACACATGGGTAGAAGGAGGGACTGAAGGGGATCTGTGAGCGGGGAAGCATCTCAGGTAGACAGAAACTTCAGGTGACTCAGGTAAGGAGGTGAGACACATGGTTGTGACATGGGGAGGGGGCGGTAG
GGTCACATCACTGGTGGGGTTTGGGCTCTCCTCCTTAAGCATCTAGAGATTGATGTCCCTCTACCTCAGCCCTGTAGGCACCAAGGCATTAACATAGCCAACCCCATTCCAGTTCCAAATCTAAAAAA
AAAAAAAAAAAAAAAAAAAACCACACATTTAATTGAACATCCTGAAATGTATAAATAGATTCATTGCAACAATACATTCCTGAGAGCCCTGGTATAGGCCTGAGGGCCACCACAGTACCCAAATGTCA
AGTACGTGTCAAACCTTAAGGGAACCTTTAAGTCCCATTACCCACCCTCAAAGAAAACTGACAGGTTTCTCAGAACCAGGAACTCCCAACATAGTAGTTTAACAGCATATGATCAAGAAAAAATGATT
AATAACAGCAGACAGAGAGATCCCACACCCTCCCCCCACCCAGAGCCCCAAAGTGCACAGAAAATAGGCCAGGGATCAATCTCCAACAAAGCAGACTCCTGGGTTTGCTGACCCAGAGACCTGGGTGT
AGATGATAGGGAAACAAGGCTGCTGGGGGCAGGAATCTGGGAGTGAGCCATTCTGGGAGGGTATTAGTGCTAGTGGACTGAGTACCTAGTACCACTTCTGGGACAAGCCACCCACTTGGAACAAAGAG
GTCACCTAAGGCCTCTCCTTACAGATTATTTTGGAAATCGTAGGGCAGGGGCTGCACCTACACCTCCTCCCTGCATCCACACCCAAGCAGCCTTGACACAGGCTCCCTTCCCATCCAGCAGTTTGTAA
GCATCTCCCCGAGGTGTGGGCTCTCAAGGGCAACGTCCATCTACACGATGCCTGGCACAGGGCCTGGCACACAGTAGGACCTTCACCGAATGTGCAAAAAATGAATGAAAGCCTACCATGTACAAGGC
CCTGGCGGCCAGAGTGAGCCCAGAAGCGAGGATGATGGAGGTGAGGAAGGTGATGGACTGGCCAGAGGTGAGATGCTGAGCCCAGGGAGATGACAGAGGCCAGGTAGAGGTGATGAAAGTCATGATGA
TGAAGTCCATGGTGACAGACATGCATGAGATAGACCCCCCGCCCCTCTCAGAACAGAACAGGAGGAAAAAGCCAGGACCCTAAGGCTGAGCCTAGAAACCTCTCTCTCTGAAGATCACTATGGATTAC
ATGTCTAGCTTGATCCCCCACCCTGAACATCCAACATGGCAGATCATTATCCCAGCATGGTGTTCGGAGAATTTCTGAGCCTGGTCATCCTACCAGGTAGGAAAAGCAGATGCCCTGAACAGGGCCCC
TTAAACAGATTCTGTTTACAGACAATTCTAGAGAGCCATCTCTCCTCCCTAAATCCATCTTAAAAATTACACTTATCATTGTGTATGCGAGAGCGTTGGTACACAATGGAGCGGTCAGAGGATAGGTT
CTGGGGATTGAACTCGGGTCCCTCAGGCTTGCACAGATAACACCGCTACCTGCTGACCCTTCTCTCTGATATCACGCATCTTATTTGCTTTTCTTTAACTGTTTCCAATTTTAAATGGGCCACCAAAC
TTCCAGGGCAAGTTGGAAAGTTGGCAAGCAATAAAGTGGCCTTCAGCATATTGTCCGAGTAGATTTGTGACTGGTTTGTCAGAACTTTTCCATCAACACCCGAGTTTGCCTATGCCAATCCTCGCTGG
TTTATCACCCAGCAATGAGTTTTCTCAGAAAAACTCCGATGCCATCAGTGACCTTCAGTTCAAATCATGGTGCTCATTGTCATCAGGAAAACAAAACCATTGCCCATGGGTATCTCAGGGAAACGTGC
AGGGAACTTACCTGGAGCCCAGGGGATGGGATGATGTCATCTCTTGCTGGTAGGGGTGCAGGTGTCTCTGTTGAAGCTGTCATGCAGCGTTACAATCTGGGAAGCTCATCCAGTCTGGGCGTACCCAG
GCCAGCACCAGAGGGCGGCAGGTACCCCAGGGAGTGGCTAGGGAGGTTGGTCGAAGGACATAGACCAATTCTTGCCCAGCCAGCTAACCCAGAAACTGGAGAGTGGGGTGGGGTGGTGAGGTGGGGTC
TGGGGAGCTGATTAGAACCCCAAGCAAGGGGGCAGGAGCTGGAGAGTGGACAGGTTGCCCCACTCCACTTAGGGGAGAGAAACCCCAATGGAGAGGGCTTGGGGCAATGGATGGGGGAGGAAGTACCC
CACTCATGGATGCGGTGAGGGGCTGTCTAAGCTTTATGGCCAGAAAGAAGAGGGAATTGGGGAGTGGGGACACAAAGATGGCAGGGAGTGACCACCAACTCTTAACCCTGTGGTGGCTCTAGCCACAC
GGGGCAAATCAAGGAGGTTGGGTGCAAGGTTGGGGCAAAAGTGTGTGTAGAGTCTGCACCCAGGGCATCTGGAGTTCGGGGGAGATCCACTCAGCCTCTTCTTACTTCCAGGCATTCATCGTTAACCA
CCACAGGACTCATACTTACACAAACCACACAACACAACACAACACACACAAACACACAACATACACACACACACACCACAGCACACATACACACAAAACACATAGCACACTATACACAACACAATACA
CACAACACACGCACATTTTCACAACTCACATGGACTAAGGCTCCTGCACAATGAGGTCCAGTGCCCACCTTAACCTAACACATGGACCAGTGAACGCAGGGGCTTATTTCTGCAGTGCCGATCAGGCA
CTATCCATTGCCCAGGCACTACCTATTGCCGTGGCTGCACAAGAACTGGGTAAAGGGGTGGGGATAGCCTCCATCTGAGGCTCCCAAATAGCAAAAGTCTCTAGAAGAGCTACTTTTATAAGCTATGT
GAGCACAGGGCTGTGTGAGCTGTAAGGCCCAGCCTTTTAGAGGGATGGCACTCGATTCTAAGTAAAAGGAGGTTAGGGGCATTAATCTGAAGTTTTGGATCAGCAGAGAATCTGGGGAAAGCATCCTG
CTACCTTTAGAGCCACGTGGGAATATTCAGTTTGGCCTTCATGCCCTCTCAGAGCCCAGGAGCTCTGTCTATGATCACACACACACACACACACACACACACACACACTTTCACTCATACTTCACACC
ATCATCCAACACCATGCAAGCAATAAAGTGCTTTGTAAAGTGCAGGTATATAGACAGTGATCTGAAATACCAACTCCCTCCCCCTCCCATCGGCCCCCTCCATGCCCAGCCCTCCCCCAGGCTTGCTG
ACTACTTCCTTCTAGCCCCTCACTACCTAGCCACCCGCCAGAATATCATCTGTATACAGATCCTGTACACAATAGGCATTAATACCTGCCAGGTTGAACTAAGCTAACATCAAATTCCAACCCCCTTG
TCCAATATGATTTGGGTCTGGGTTGTGAGAGAGTCACTTGTGAAACTTAAGGGTGTCTAGGACACTACCACCAGCCCATGATCCTAACTAGGGTCCTCATAGGGCAATCAGGGGCCTCTCTCCTTTAT
TGAATCCAACCTGTCTTCTGTTGACTGTCCTCTCCATCCACCTGGCCACTAATGACTCCACTGGGGCTTTCTAGAAGTCTACATCACCAAATAGGACACTGTGTGGGAGACATGGGGTGTGGAATCCG
GAGCTGGGTCCAATGTGTCCTGTGAGGATGGGAGGAGGGTCAGTTAGAAACATCTACTATGAAAATAGGTATGTGAAAACTTAAGAGTGTTGGGGGGGGAGTGGGGGAAGGGAGCTCCTTGCAGCCTG
CCTGCAAGCCCTGACACACTCCAGCTCAGCCTCCATAATGGCAACTGCCAGAGAGGACAAGAGGAAAATTACAGTCATCGGGAAAAAGCTGTGGCCCGAGCATCACCGAGCCACAAGCCCTCTACACT
GAGCCGGGAGTATCAGGGAAGCTCGGACCCTGCTCAGCTCATCCTAAGAGGGACAAAGGCTATGATTTTCCTCTCCAGAGTTATTATCTACCTCCCTGCCTCTGGGCTCTTTTGTCCAGTGGCTATCA
TTCAAGAGGCTAGCCATCCCTTGGAGGTAATCATCGGGACCACACCATTTGATTCTGAATATTATGGGTTGGAGAATCAGGTGGGTGGGAGAGGACACAGACAGGTGACCCTGCAGCAGCCTGGAAAA
GAACAAATTGAATAATGGGAAACTGAGGCTAGAGGCCTGGGCAAATACCCAGGAGTACCTAGATAGGGAGAAAGAGCACCACTCTGTTCTTCCTTTCTCTTACTCTCTCTCCCTCATCGGGGGCTGGG
GGTGGGGGTCAGAGCTGGTGCTAGAACCCAGAGCCTCACAATACTAGGTAAAATGTCCATCTCTTAAGCTATACCCCAGCTCTCACCTCTCCCTGAAGTCAAGGCTGTGCCTGATGATCTGGAAGCCT
ATGCCGTTCTCGAAACCGCCACGTTCTGCCGGAGTCTTGTGCATGCAGCTGGGGAGTGATGTCTCTGAAGATGTGCACACTCTTCATCTCGTGAGTCGGCTTCACCAGTCTTTTGTTTGGCCTCAAAA
TCCGTTGTCGAGACGTCTAGGAACTCAGCAATCACCAGTTCTTGGAAATCTTCTAAAATATCTTGGCCAGATGAGAGAAGGGGTGAGAAGAGACAGTCCTCGAAGATGGCCTTGCTCTTTTGTTTCAT
TCCCGGGTCTAGGATTCCAGTTACTCATCAAAGAAGTTCTTGTGCACACAGTCCAAATTCAGCTGAAATGTCCAGGCAGGGTCACAGAAGTGACGGTGGCACCATCAGAGGGTTTGTTAGCTGCTTCC
TTTCCTCCACACTCCAGCTAAATAAAGAGTCACGCTGGGAGATGGGACCATGTCAGAACAGCATAACTAATGAGAGCAAGTCCTCAGAAGCCCCCAGTACATGGGCTGCACAGTTGGTCTGTCCAGAG
TCACATTCAAGGCTCTCTCCTCCAAGTGGTTACATTCTTTGTCACAGACTGAAGCCCTCCACGATGCTCCTAGAGTTTCTGAATAAGTCAATATTTTTTTTTAATCTCTTATTTATTCAATTATCATC
TCTCAAGCTCAGTGGCCAGGATGGGCTCGATCAAGTCCCAAGAGGACAAAAGATGCTACCAAGAAGCCCAGAACAAGCCTTCAGCTCCAAACATGGCCTCATCTGGTATGTCAGTGTCCATGCCTCCA
ACTATGTGGGAGTCTCCTTTGTGGCTGATGCAGTCTTTATAGGTGTCACAACAGTCTTGACCTGTCCCCAGCCTCAAATTCAGTGAACTTCTATTGCTGGAAGGAGGCAGCCCTTTCTTACCAGCCCT
GAAGGTCTCAGCTTGACACCAGGCTTGTGAGTGGGCGTTTAACACCTTGCTCTGGGAGAGGAGCTAAGCCACAGATACTAGGTTGGGTTACATTCCAGTCAACTTGGCCTTCCTGTGGGGTCAAGGCT
TGTTGGTGCATGTCCAGCCATGAACCCAGCACAACTGAAAAGCATAAAATGGTGCTTTACTCTTAGCATTTTGTACTGTTGGGCAGCAATCATTGAAAGGTCTTTATCTCCAACCCGTGACATCGGCT
GTCATGTTCTTACAGCACTCGGTTCTGCTACCAGGAGTTTCTTTTCCACGTTTCTTCTGAAAACTTGCAACTGTCTCTCTCTTTTCTCTTATGTTAGAGTCATTGAATTCCATGGGCCACAGGAAAGC
ACTGCCATCTGCCCCCTCCAGGATCAGGTCAAGCTTTGGACATTATATTCAGCCCTGTCCCAGGAAAGCCTGTAGTCTCCAAGTTTTTTCCTCAATTCCAGATATCTGAGTTTTTCTCAAAAATTTAA
ATCTGACTTTCAGCTCTAGAATACCAAAGAGGTAACCTTCTTCTGGACGGATGATCCAAAGTAGATCGTCACAAAGGTCTCCCTTTCTGGACACTTCAATTTCATTAGAGGATAAAGATGGGATCTCC
ACTCTATAAGAACAGAGGCCTCTCTCTTGACGAACCTATCTGAGCGTCACCAGAGCTGCATCTTTAGAACAATATGGAAGTCTCTCTTTCTAGACACCTGAGCTTCATTAGATATTGAAATGAAATTC
TAGATATAGAATATGAAGAAAGTCTCTATTTCTAGACAATCAAACTTCACTGAAAATGGGCTGGATTTCTGGCATTAGCATATTTCTGGACCTTTGATCATCACTGGAGACTAGAAATGCAGAATTGT
AGAACACTATAAAGAGGTCTTCTGGGTATCTAAGTTTCAGAACCTTGAACCGGGATTCTAGCTCAAAAATGTTAAGGAGGACCCTCTTTCTAGACTTCTGTGCTTCTGGCATCTGTGCTTCATCAGCA
AATGAAAAGTACAGTCTTTGTTCTAGAACATCGTAAAGGGTCCTCTTTCTGGATAATTGGGCATCAAAGATTAGAGGTGGAGCTTAGCTTCTGAACAGAGTGGAGGTCCCCTTTCTAGATATCTGGAC
ATCAGAGAGTGGGGATGGAGTCCAGGTTCTAGTACATTGTGAAAGTTCTTTATGGATGTCTGAACGTCATCAAAGGCTATAGATGGATAGAGTTCTGGGTCTATAACATCATTGAGAATGCTCTTTTC
TGGACATCTGTGCTTCATCAAAGGCTGGAGGTAGATTCTTAGGTCTGGAACATCAGAGAGGTCCCTCTTTCAGGACATCTGAGCTTCATCAAAGGCTAGATAGAGGGTCCTAGATCTGGAACATCAGA
GAGGGCCATCTTTCTGGACATCTGAGCTTCATCAAAGGCTAGAGAGAGGGTCCTAGATCTGGAACATCAGAGAGGGCCATCTTTCTGGACATCTGAGCTTCATCAAAGGCTAGAGAGAGGGTCCTAGA
TCTGGAACATCAGAGAGGGCCATCTTTCTGGACATCTGTGCTTCATCAAAGGCTGGAGGTAGATTCTTAGAACTGGAACATCATAGAGGACTCTCTTTCTAGACATCTGAGCTTCATCAATGGCTGGA
GGGAGGGTCCTAGATCTGGAACATCAGAGAGGTCCCTCTTTCTGGACATCTGAGCTTCACCAATGGCTGGAGGGAGGGTCCTAGTGCTGGAACATCAGAAAGGTCCCTCTTTCTGGACATCTGAGTTT
CATCAAAGGCTGGAGGTAGAGTCTTAGGTCTGGAGCATCAGAGGAGTCCCTCTTTCTGGGCTGGAGGTAGATTCTTAGGTCTGAAACGTTAAAGAGGTCCCACTTTCTGGACATCTGAGCTTCAAAAG
CTGGAGGGAGGGTCCTAGTTCTGGAATTCTGAGCTTTATCAAAGACTAAAGGTATAGTTCTCACACTAGTTCTCCCTCAAGAGCATCCATATTTGTGAACATCTGAACATCACTCAAGAATGGAGCCA
GAGTCTTAGCTCTAGAGCGACAAAAGAGCCAGTCTTCCTGGATATCTACAGTTCATCAGAGAGAGATTGAGTCTTGATTCTAGAAAATCAAAGAGGTTCCTCTTTTTACACATACAAACTTCACTGGA
GACAAACAAGCTAGAGTCCTAGATCAAAATTATCAAGGCGGTCTCTTTTTCTGAGCTTCTTCAAGAACCATCGTTGAGTTATAGTTTTATATTGTCCATTTCTCTGGGACATTTGGGCTTTGTGAGAG
ACTGGAGGTGGATTCCTGGCGCTAGAAAACTGAACAGTTTCCAGATGTTTATGCTTTGGTGGTGACTGGTCTAGACTATGAAAGACTTCCTTTAGACATAGGAGTTCTCTTAGAGGCTACAGCTGGAG
CTTGGCACTAGAATATCAAAGAACTACCTCTTTCTGGTCTTCTGGGCTTGACTGAACACATGAGCGAGAGTTAGAGTCCCAGGTCTAGAACATCACAAAAGAAAGCCCCTCCTTCTTGGTCCCTGAGG
TCCATCAGAGGCTGAAGCTGGGCTCTGTGCTCTGACAAATCAAAAGGGCTTACCCTGGATGTCCAGAGTCTGTCAGAGACTGGAGTTGATGTGCTGGCCCAAGGACATGAGCAGACTCCTGAAGCTGG
GTATCCTCATCAGAGGCTGGGTTGGGACTCAGGGCTGGACTATAAACACAGAACTCCACTTAGAGACACTGACAAAATGTGAGGCTTGTTTGAAAGCTGGAGATGAGTTATTTTCTTGGGAATATCAA
AAAGGTCTTTTTTTTTTTCCTGGACATTTGGGCTCCATCAGAAGCTGAAGTGGAGGCCTTTTCGGTAACGCAGCATTAGGGCACTCACTCTGGAAGCCTGAGTTTCAAAGAGTTCTTCTGGGCTCTTG
GACTCTCTCGGCTGGGCTCAGCATCTGGAGGCATGTCTTCTCACGGTTGTCTGCACTGCGACTCAATCACACATGCCAAAGTCCCCATCATGGCTGGTACTGGCTCTTCCAGGCTGGGTCATGCCCAA
GTCTTGAAGATGGTGCTCTTGGCAGGGGGTGTTCAGAAGAGCATGCAGCTGCACTTGCCAGGTGCTTCTCGGTGCGAATGAGGAAGTGGGAAAAGGAGGAAAGACAGAAGGGGGGAGAAAGAGAAGGA
TAGAGGAGGAAAAAAGGAGAGGAGAGAGAAGAAAGGGGAAGATGAAGAATCAAAAGAAAAAGCAAAGACGTGTAGGGAAGAGGCAGAGGAAGAAGAAAAGTCAGAAGAGGAAGGAGAGGAAGAAAAAG
GATGAAAAGAGGGAAGAGGAGAGAAGGGGAGGGGTGACGGTGGCGGTGGCAGTGGCAATGCAGCAGTGATCTTAGTAGATGCTGGTCACTGTGTGGCAACTGTGGTCTTGGTAGACATGTGGCAGCTG
TAGTGATTATGACTGTCATCTTCCTCTTTGCTGGGGTAATGTTCGTGTTACCATCTGCTCTACCAAAACTCAGCTCCATTTCCCATCCCCTTGCTCCCAATTCCCTCCTCTCAGCTGCTCAGGCAGCC
TGACTGTCCCCCCAAGGCCTCTCAAAAGCCATGAGGGTAGGGCTCACCTCCCCAAGCTCAACCAGCATACCTGATGCCAGGCATCATGAATGTCTGAGCACTCACTCAGACCCATTCAGGAACCACTT
TTGTAGAAGCTGTGTTGGCCCCAAGTCCCAATGGGACCACCCATCTGGGTCAAGATGACGCCTCAGCTAGGGCCCTGGCATAGCCCCGGGGAGTGTGGAGGGCAAGGGGGGTGCACAGAACTCAGCCC
CGGAGCAACATTTTCTCTGGAGCTCCAAGGACCAGAGCTGTGAGCCCCTCAGGCTCCAAAGCCAGACCTCCCACAGCTCTTGCATGGCTTCATTTCCAGAAGGAAACTGGCATCCCGAGCACACGAGG
AAAGGGTTCTCCTAAACCCACCGAGCACAGGCCCTTCATCGGGCCCCAGTGTATCCATCTCTTAAGCACACACAGGGCAGCACAAAGGTGACTTTCTGGGGTTTGAGGCAACTCCTCTACCCCACTAC
ACTACAAAAGGAAGCCCCAGCAAGACACCCACCCTCCCTCGTATTAGTAGCACACCCATCACTGCTTTAGTTAAAACAAGAAATTTATTGAAAGCACCATGAGCCACTAGGCCCCATGCTTCTAAGCA
CATTGCGGCTGCCTCACAACAGCCCTGTGAGGTAGGAACCTGAGCCCATTTCACAGATGTAGACTCAACAGTGAAGACACAACAGCCTTTCTCCCACCCCCCCAAGTCTCAGGGTCCATGGGTAGGGA
TCAAGGCCACATGCCTGACCCCAGGGTCAGCGCAGTTCATCAGTCAGTAGGTGGGTCTCTCTACTCAAGGGGAGGCCAGGGTCCAGAGTCTTGGGTCCAGCATGTCCCACAGGAAATGTGCAAGGCGT
CCCCGTGGCTGTAGAGGCTGAGAGAGACACAGCTGCAGATGAAGCCATCTGCTCCCCATCCCCATGGCAGATAAAGAGTTTTCATGCACTAGGCAGGGTAGGAACTGGAGGGGGCAACCCAGCCCTGT
GCTCAGAAAGCCTGAGCTATGTAGAAGGCCCAACTTCTGGACAGCCATGGGGGTGGGGCAACACCTACACACCAGCTCCTGACTTTTCCAATAAATAAAAACCTATTCTAGGATTTTCCATCTTTCTC
ATACCACCCCCAAGACTTCTAGCCAATTCACAGTCTATTAAACCTTGGTGGTTTTCCAAAGACTTTGGCCTTGCCCTCCTAGAGGGGTGTTCTTAATAGTCTTCCTGGTCTTGTATCTCAGAGCCTCC
CATCAAAACTGCTGAATCCTAACATTTGAAAGCAAGGCTTTCTATGTCGCTCCAGAGCTGGGTAGGTGCTACCCTCCTGCCCTCCACTCTGTCCGAGTCTCACATGGACCTGAAGTTTCAGAAACTAA
GGTACATCTGTACCCAGGGCCCACCTCCACAACAGTCAGTATGGGTTAGCAGACATGAGCACCTGCATACCAAGCAACAAAACACTCGTTTTCACACACACACAAAAAAAACCTCACTGAATCCCCCA
ATCAAACCAGGTTGGTTTGACTATTTCTAGGATATGGCAAACAGCCAAGGCCACCACACGTTCCACAAGGGACAAGGATGACCAGAACTCAGACCTTGATTCTCATGAGCCACCATATGATGGGCAGT
CACTAATGACACCCTTTGTACAGGAAGAGAAACTAAGGCTGGGGATGATTCAGGCAAGCTGCTCAAGGTTCAGTTGGAAGAAAAACAAAAAACAAAAACAGGTCTGATGCCCAAATGGGTAAGACCCT
GGGAACCCCTCCCCCACCCATGTGCCTACGGAGCACTCTGTAGAAAAGAAGAATTCAAGGGGTCCAATCTCCCCAGTCTGCCAGGTGCTTGAGGCTGTACCCAAATCTCACAGGTAACTTCTAAGTCA
GTGCTGATTGTCACCAATGGTGGGAACAAAGGCTTTGGGGGCGAAATAATCTCCTTTCACCCAGAGAGAGGGGCCTCGGTGATGATATGGGCACAGCCAAGTCCACCTTAGAATTTGGGAACTGCCAA
ACAACTCCTTTTCAGGATCACTCAGGTCAAAATGTCAATGAGGACATTTTAGCTCTCAGAAAGTTTTATTCTGGACATAATATCTCCAAAGCAGTGTTTCTACCAGGAAGGGTGTCCTGTAGCTGACT
AGATCCTGGGGAAAGTCCTTAAAGACCTCCTAGTCACCGGCCTATCCACATTCACTTAGCCTTCCCTACTTCATCATGGAGCAAGTATTAGGTGCCCACTACTTCAAGAGGCAGGGTGACATTGAGTT
GGAGCAAGCCTAGAGCTTAGTCACAATCTAAGCATTCCCTTTTTGCCAGGCCCCTGGCTTCCCTTTCTTTACTTCCAAGAGACATAAGCTACCTAAGAGTCACCCAAAAACCTGGCCCACAAGGGGCC
AAAGGCCCATCTGAGACCAGGCACCTAGACACAGAGTCAAAATTACCTGAGCAAATGACCTGACCCACATGTGCCTACCACAAGACCCCAGAGCACAGAAGCAAAGGTTCCAAGAAGTTGTCAAAGAC
AGGATGAACTGTAGCAGTCACAGACACAGCCTGAGGGAGGCAGAGTCGGGATTTTGGTAATGGAGTATGATAGGGAAAGACATGGCAGCCAGAGGGAACAATGAAAACACGGGGTCCTGAGCCCGAGG
ACACAGTGACAACACCAAGGGTTTAAGAGCATCTAGGGCTGAGACACCAGGGCTTTGAAAGCCAGAGTAACACAAGGAACTGAGCGGAGGCTGGGCTTCTGTGCAGTGGGTGGGGGGGCTTCTTGGCG
TGGACTTGGAACAAGAGTGGAAAAGTGGAAGGCTGCTCGCCCAGATTCACAGGACGAGGACTGGGGATGGAATCCAACATCATGGAAAGAGCCTCGTGGGAAATGTGAATCTCAGACAGACATGGACT
GGGACACTCCGGGACTGGGAGACCTGGGAGGACACAGCCTCCTTGCTCCTCCCTCCATGCCTTACCCTGCCAGGAAAATACTAGGTGGATAGTGGGACACAAAGCAGAAGGGAGACCATTCTGAGTGC
ATGCCAGGATCAGGCAGGGGTGAGCCTAAGACACTGGGCTTGCTGAGGTTTTATTTGGTGGAGTGGAAAGAGTTATTCACACATAACATGACTATTGTCCCTGGTTCTCAGTCTGCCCATCCATAGAA
TGGGACCATGCTGAGGACAACAGTAAAGTGTGTAAACCTAAGCTCAGTCCAAAGCAGAATTTGGTGTAGAGAAAGCTAATTTTTCTCATCTCCTGGCAGGGGAAGAAAGGGGGAGCGGGGAGGAGAAC
AGCCACCCAGACCTACCAGCTAAAAGTGAGAGAGCAGTAAGAAAAAATTCAAGGATGTCATAATTTGGAAGCCCCTCTATTGACCCTTGGTTCTTGGCACTGTCCCAGGGGGCAGATATGCACACACC
ACATACACAGAAACACAAGCTTGAAGAAGCATCTACCAACAGACACCACCCCTCCTAATGCCCCAAAGCATAGTGGCCCAGCCAGCTTTGGCCTTCACACAACCAGCAGCACCAGCCACCATGATGGA
AAGGAAGGGAAGGCCAGGGCACCACAGAGGGACTTAGACGCTAACATGCATGAATGAACCACACCAGATTTAGCCAGGACCACACAGCCAGCCTCGAATACCACATCGACGGCTGGATATACAACCTC
AGTGTCCACAGTGAGACTCTTTATTCAGTGACCACTAATAACGGTATAGGTTGTGATTTCAAGCCAACCCCATCATGGCACCATCCCTGGTGACAGCCAGCATGGACATCACACTGTTACAGCCGATC
AGCCCTTAGCCCTCACAACAACCCTGTGAGGTAGGCTTGCCAGTGACGCACACCTGAGAGAGAAGAAGACTACGGGTCAGAGGGGCAGAGACACAGCTTAGCAGCCCTGCCAGATCACACCTAGGTGA
GTTCCAGAAGAAACAGACTCTCAGCAGAAAGCAGGACTTTTTTTTACTTAGCATGAAAGACAACAAGGCAAGGTGCAAAACAACCCAGGACAGCAGTGGCTGCTTAACATGTTAAGGAAGAGAGATGG
CTTGATATGGGTTCAGATACATTCTCCATTACAAACCACTGAATGAGACCATACACATCTGCCCCTAGGACCTGTTACAATTGTTAGCTACTCATCTACCTACACAAATACAACAGAAGGTCACTGAA
GCCCTACCCCTGGCCAGGCACTGTGGTAGGCACCAGATCTCAGGCAGTTTGGCCTGATGCTGTTAGTGGGAGAGAGGACATTGGGAAAGGGACAATGGGGTCTGCCAGATCGGGCCGAGTGCTCCCCT
GGGAAGAGCCTTTTGGAAAGGGATGTAACTAGGTGCCATATACAGTTCTGAGTCAGAGGCTTGGTCCTCAGTCAGAGAGCTAAAGACAACCCCAACCTCTCCTAGAGGTAGGTGTGGATGTGTCCGAG
GGGGGCGGAGGGCACAGGTACTATCTAAAGAGTCCCCTATCCCGTGGTGTTAAAGTCTCTATAGGAAAATATACAAATTTAACAGATACAAAGTATTCCCCATTATACCCAAGCAAGGCCACCCCCAC
TCCAGGGCTAGGGTTTCCAATGCTCTGGCACACCCCCAGGGACACATACACTGCCTTTTAGGGTCACAGTCAGAAGTGTCCAGTTATACCAATCCTCACAACAGCCCTGAGGCAAGATCCATCACACA
ATTTGTCCAGCTCCAGGTTCTGGCCTTGCCGCCCCTACTGCGTCTAGTGGGAGGAGAACTCAGAAGAGCCCTGCGTCTCTTCCCCTTCACAGCAGAAAGCTGAAAGGAGGCCTCCCCTAGCATGGGTC
CTCCTGAAACACACAGGGGTTTGCAAAGTGCCATGTGCCTTGCTCGCCTGGGTCTGCGAATGGATTATTCAGAAAGGACATTGGGACATGATCCTTGTCACTTGTACGAGCATCCATCTCCTGCAATT
TTCTCTAAAAAGGAGCCAAGCATTAGCTGAGCTCCAAAGTGGCCAGAACGGCTCTCAGATCATCCTCATAGAAGAACAGAGTGTCTCACAGCCTTGAAAGCCTGCTCGCAGCCAGAGGCAGCTGCTTC
GTGCTTAGTCCACTCCCCATTTGGGCCTCTTAAGGATCTGGGCTATGATTTCTGAGCACCCAGGGAACACAGTTTGCTGATTACTAATCAACCTAGTTTTGTGAGGAACAAAATTGGAGAGAGCAATC
AAGCTGGCAATAGAACTCAGACCTGAAGTTTGAATTGAAATCAAGGAGCTCCTCTTATTGGCCACACAAACACAGCTTCTTTACAAATGTCCCCATCTTTTCTTTCAAAGGACAGTGGTGCAATGGGT
GCTTGTGAGCCGGCTCTAGTATAGCACTAGCTAATTTTTTTTTTTTTAAAGAGATGCTTGCTGGCTGTAAGAGAATGAATGAATGAAGGTGCGAAGGAATGGGCACACGAGTCACAACCACTGCCATC
TGGTGGAGGAAGCTGCAAAGGTGAAGGCCAAGCTCATGACAGGGACCATGCACCAGGCAGTGTGAAGCCTGGGGAGGCAGCTCCGCGGATGGTGGGAAGGGCCAGCCCCAGGGCACTCTGGGAATCTG
GCCCTCCTGGATCACAGGAGGAGGGTGTGAGGTGTGAGAAGCCTTATGGAGAAAAAGCTGTGGTGATAGGGGTCCAGCTGGGACGTGCTCAGAGCCGTGACCTAGGAGGAGGAGGAGGAGGCTGTGAA
TGGGGGCCTTGCTTCATGACCACAGCCCATGGTATCACACAGCTTGCCCAAGGTGAAGGGGTTTGCTTTCAGGAGAGGGAGAGAGGCCCAAAGCACCAGGTCAAGTGATGGAGGCCCAATGTGTGTAT
GCATGGATGGATGGATGAATGGATGGATGGATGGATGGATGGATTGACTGACAGATGGCTAGATGGATAGCCAGATGGATGGGTGGATGAATTAAAAGTCAGTTGAAGTCACCACTGGCTTTCCAAGC
TTCAATGTCCAGATAAGCATGGGGTGAGAGGGCTGAACACAGGCAGACACGCTAAGTGCTATAATAGAGTGTGGGAGGGAGTTCTGGATGGCAGGATGAGCTCTCCCGGAACACACACCCTACCCAGA
TGGCTATAACTGCCCTGTGAGGAGGTTGGGAAGAGCCGAGACCATAAAATGGCCTTGCTCCTAGAACTAACCTGAGGGTCACATCAGTCCTGAACTGAATTTCTCATTCATTCCCTAAATTAAGACCA
CACCTGCCACTGAGGTGCATGGGAAGACTAGAGCTAAGGGGATGTCTAGACAGAGCACTAAGAAGCCAGTTCCTCTAAGACATGGCCTCAGAGACTACACCCCAGAACAGGGGAGAGGCATATATGTA
GTCTATCACTCAGGAGGACAAGGTGGAGGACTGCCACACCACAAGAGGTACAGAGCACAGGTCAGGGCTCACAAGCTAGAAATGCATGGTGAACCCAGACACAAGCCTAAAAGTGTTTTCTACCTGCT
GGTGCAAGATATCAGCCTCCCTGTTTCCCAGGGTAAGTAAATTCTAATGCCGAGCTAGAAGTCAGCTGAGCCTCTCACATCATTCTGTAGATATCTGTGAAAGGCCATTGCCTAGTCTAAGGACACCC
TCAACCAAGAGCCTGAAAGAGCCATGAGCCACTGGACTTGGACAAACAGTTCACAGAAGATAAGATACAATTTGTTAACAAACATGGGTGAAAAGTATTCAGCCTTCATTAGTAATTAGAACAAGTTT
TACACACACAAAAGCATTTTTTAACAGAGAGGTGAGGAAAGTCAGCAGACACCTTAAATACTAATACATCAGCTTAAATGCTAATACATTATCAGACAAGATAAAATACTGTAGGCTTTCTTCAATCA
ACCAACAGCCATTCAAACATTACCCTTTCATCCAAGAAGCTCAACCAGAGAATATACCCATCCATTAATTCACTCACTCATTCATTCATTCATTCACTCATCCATTCATCTAGCCTCTCATCTGTCTG
CCAATCTTTCAATCACTCCATCACTCATACCTGTCCACCCTTACACACACACACACGCACACGCACACATGCACACACGCACACACGCACACGTGCACACACGCACACACGCACACACACACACACAC
ACACACACACATACACACACACACACACACACGCAGTCAACATTCATAGACATCCTACAAGAAATACAGAGCGCAGTTCCACAAGCTCCTTGCCCTGAGTGGGCTCACAGTCTAGCAGAAGGAAGCAA
GGAGAAAAGAAAGGAACCATGGGAAGAGCTAGATGTAGGGGGCGCTAGGGATGCTGGGAAAGCTGGTTGTGCAAAGCCATTAGTTATGGTGTCATCGGTAATGTAAAATAAAAAAAAAAAACAGGACA
GGAGATGATCATGCATCAGCAACAGTAAGATGGGTAGATCATTATGTCATAGCCATTCAATGGAACTCAAGCAGGTGAGAGAGACCATGGAGCAACGAAAACGTGGACAGCAAGATGCTCATTGCAAC
AGACACAAAACACCAACAGAAAAGTAAGCACCACCAATGGAGCTT

hide sequence


Protein RefSeqs	NP_908998	(Get FASTA)	NCBI Sequence Viewer
	XP_030102657	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACF20046	(Get FASTA)	NCBI Sequence Viewer
	ACF20051	(Get FASTA)	NCBI Sequence Viewer
	DAA01153	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000115957
	ENSMUSP00000115957.3
GenBank Protein	Q7M732	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_908998 ⟸ NM_184109

- UniProtKB:

Q7M732 (UniProtKB/Swiss-Prot), B4YB44 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MIEPSEDSFETMMELKNPSSKQMESSEGSSNTVEETPGSSGAQAGAQAGAQAEAQAETQVEAQAEAQAEAQVEAQVEAQAGSDSGPAQEEKEPPSGPLKEMQELPTNLLQEVEEPSSGPHQEMQELPT
DLLQEVEEPSSGPHQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSGPYQEMQELPTDLLREVEEPSSDPCEASS
NDLPQDMEESSDDGSNQESSDGSNHELSNGSNHESSFGSNPESSDVSNLESSGGSNQESSDGSQKESSYDSNPELSDNSNQELSDNSNQESSDSSNQSSDISNQEGSEPLSEASDYSMDETINSSETQ
SDQDDTDLGDDEEEEEEEGGEEEGQPKNSPEEVVATMGNVISLFLRMQDLKEQQRVAERLMMQAINEGRLPSLRPFSGDRRDYHEFVVLCQMTMQNYPSMLYNDELRVKFVIRHLTDLALEWANDLVE
QNSPVINNFSAFLEAMSEKFEYRQTLRVAEDAMFNIRQGNRCAADYINEFRGLIPTLGWPDEVLQAHLCQGLNEEIRHYLFRIPQPNSLDNLIVLVLQLEEKLAERRALLRLPPESRPRSVAWMDAPA
PEKWRVSSWLPNEFHPDIDRDHLFLLLLVRVDPYHSVAVRALVDSGAEGNYMDERFAQEHYVELYEKPYPQIIQGVDGIPIGNEPVWLCTEPLVCVHQKHYEYIEFDILPSPNFSIVLGMKWLRTHAP
EVDWMRGRCTFHSPYCLRNCFTPPPPCIALETYSISLLPGLPHTYSDLADVFNPREADDETSDQPSSDGSDDLSESEPSELQQAGDSDQSGVFYESGARETLEPVSARMQEKARQQEKAREQEEYWIL
YDMLTDRQDYTQMVPELFDQLHGAAWFTKLELLGIKESEMRHTVTHTEDTWRASFGFGLHQMRCYRPFTMNSYSDEGNNIVHFILKDILGLFVICHGREVLVYSMSQEEHSQHVRQVLVRFRYHNIYC
SLDKTQFHRQTAEILGFNISPKGVKLNKNLMNLIVGCPVPGSRRCLQSVIDLVYPYRHFVENFAVIAAPLVRQLLSSEPYYWGEEEQEALESLKRAFRKSPVLYHPKPQNPFYLETDITGSFLSASLV
QTDDETGKKSTCAFYSRPLSTMEVEYPRVEMRILPIRAAFMVWCRYLENTEEPIMILLNTEDLASLNNDRLTVLLPGHWVFFFSHFNFGVMEMPAEGDTQALFRRCWNQRGFRARFLRPLLLMSIRAN
LRYFDRSSETEDKEDDEEEEEEDGEEEEGEEEEDGEEEEGEEEEDGEEEEEEEEDDEEEEGEEEEDGEEEEGEEEEDGEEEEGEEEEDGEEEEGEEEGEEEEEGEEEEEEEEDEEEEEEEEEEEEEEE
EEEEEEEEEEEEEEEDEEEEDEEEEDEEVPSMVRELLAAIPMDHILNGLLAHFSVAQIRAVVLNFFRGLLYWKSLLGVAAVLVMLRARQPLSPVPAPNLEVARPQHRHTLRLILDSTLIASSGMATAI
AQLLSQMPPLVGANTLPARELAELFLGPRCWHRNALHSQPPRGMRFTPGFWLTLCEFFGVRVNPEDDVFPDPYQHRYLELHVVGDEDVVLREALQDDLQRYRQCGLHDGLQDTSQDAQDNDVQEDLFG
DQEAVTFRPRNLLDPEVLDFLNNRLLYTLGTDGRLTLLSRDQVAQALTRFLAMASRMALPSPAREQARLEELSDSDDELD

hide sequence

RefSeq Acc Id:	XP_030102657 ⟸ XM_030246797
- Peptide Label:	isoform X1
- UniProtKB:	Q7M732 (UniProtKB/Swiss-Prot), B4YB44 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSMUSP00000115957 ⟸ ENSMUST00000149046

Protein Domains

DUF4939 Reverse transcriptase/retrotransposon-derived

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7M732-F1-model_v2	AlphaFold	Q7M732	1-1744	view protein structure

RGD ID:

8679242

Promoter ID:

EPDNEW_M17652

Type:

single initiation site

Name:

Rtl1_1

Description:

Mus musculus retrotransposon Gaglike 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	12	109,600,341 - 109,600,401	EPDNEW

RGD ID:

6823377

Promoter ID:

MM_KWN:12722

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain, MEF_B4, MEF_B6

Transcripts:

NM_184109

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	12	110,829,071 - 110,834,402 (-)	MPROMDB

RGD ID:

6823171

Promoter ID:

MM_KWN:12723

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain, MEF_B6

Transcripts:

NR_002848, NR_029952

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	12	110,830,121 - 110,830,902 (+)	MPROMDB

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000006551
	ENSMUSG00000085925	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000149046	ENTREZGENE
	ENSMUST00000149046.4	UniProtKB/Swiss-Prot
Gene3D-CATH	2.40.70.10	UniProtKB/Swiss-Prot
	3.30.70.270	UniProtKB/Swiss-Prot
InterPro	DNA/RNA_pol_sf	UniProtKB/Swiss-Prot
	DUF4939	UniProtKB/Swiss-Prot
	LDOC1-rel	UniProtKB/Swiss-Prot
	Peptidase_aspartic_dom_sf	UniProtKB/Swiss-Prot
	Rev_trsase/Diguanyl_cyclase	UniProtKB/Swiss-Prot
	RT_RNaseH_2	UniProtKB/Swiss-Prot
KEGG Report	mmu:353326	UniProtKB/Swiss-Prot
MGD	MGI:2656842	ENTREZGENE
NCBI Gene	353326	ENTREZGENE
PANTHER	PTHR15503	UniProtKB/Swiss-Prot
	RETROTRANSPOSON-LIKE PROTEIN 1	UniProtKB/Swiss-Prot
Pfam	DUF4939	UniProtKB/Swiss-Prot
	RT_RNaseH_2	UniProtKB/Swiss-Prot
PhenoGen	Rtl1	PhenoGen
Superfamily-SCOP	SSF50630	UniProtKB/Swiss-Prot
	SSF56672	UniProtKB/Swiss-Prot
UniProt	B4YB44	ENTREZGENE, UniProtKB/TrEMBL
	Q7M732	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-08-22	Rtl1	retrotransposon Gaglike 1		retrotransposon-like 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar

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