Ttc29 (tetratricopeptide repeat domain 29) - Rat Genome Database
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Gene: Ttc29 (tetratricopeptide repeat domain 29) Mus musculus
Analyze
Symbol: Ttc29
Name: tetratricopeptide repeat domain 29
RGD ID: 1315913
MGI Page MGI
Description: Involved in cilium movement. Localizes to sperm flagellum. Is expressed in 4th ventricle lateral recess and lateral ventricle choroid plexus. Human ortholog(s) of this gene implicated in spermatogenic failure 42. Orthologous to human TTC29 (tetratricopeptide repeat domain 29); INTERACTS WITH 4,4'-sulfonyldiphenol; benzo[a]pyrene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700031F13Rik; tetratricopeptide repeat protein 29; TPR repeat protein 29
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39878,939,911 - 79,120,955 (+)NCBIGRCm39mm39
GRCm38878,213,282 - 78,394,326 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl878,213,297 - 78,394,326 (+)EnsemblGRCm38mm10GRCm38
MGSCv37880,737,241 - 80,918,225 (+)NCBIGRCm37mm9NCBIm37
MGSCv36881,109,414 - 81,290,398 (+)NCBImm8
Celera882,486,892 - 82,670,357 (+)NCBICelera
Cytogenetic Map8C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21267068   PMID:31735292   PMID:31735294  


Genomics

Comparative Map Data
Ttc29
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39878,939,911 - 79,120,955 (+)NCBIGRCm39mm39
GRCm38878,213,282 - 78,394,326 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl878,213,297 - 78,394,326 (+)EnsemblGRCm38mm10GRCm38
MGSCv37880,737,241 - 80,918,225 (+)NCBIGRCm37mm9NCBIm37
MGSCv36881,109,414 - 81,290,398 (+)NCBImm8
Celera882,486,892 - 82,670,357 (+)NCBICelera
Cytogenetic Map8C1NCBI
TTC29
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4146,706,638 - 146,945,882 (-)EnsemblGRCh38hg38GRCh38
GRCh384146,706,617 - 146,945,882 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374147,628,179 - 147,867,034 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364147,847,629 - 148,086,484 (-)NCBINCBI36hg18NCBI36
Celera4144,948,722 - 145,187,595 (-)NCBI
Cytogenetic Map4q31.22NCBI
HuRef4143,355,394 - 143,594,202 (-)NCBIHuRef
CHM1_14147,605,049 - 147,844,310 (-)NCBICHM1_1
Ttc29
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01933,205,576 - 33,424,955 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1933,206,026 - 33,424,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01944,097,159 - 44,315,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41931,434,795 - 31,666,000 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1929,031,077 - 29,241,884 (-)NCBICelera
Cytogenetic Map19q11NCBI
Ttc29
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554282,378,631 - 2,571,259 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554282,378,498 - 2,571,246 (-)NCBIChiLan1.0ChiLan1.0
TTC29
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14150,694,682 - 150,937,941 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4150,694,813 - 150,938,434 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04139,037,462 - 139,281,009 (-)NCBIMhudiblu_PPA_v0panPan3
TTC29
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1545,093,132 - 45,338,159 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11545,093,105 - 45,338,890 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ttc29
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365352,468,640 - 2,658,628 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC29
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl881,746,489 - 81,982,760 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1881,746,479 - 81,981,617 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TTC29
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1793,209,932 - 93,457,501 (-)NCBI
ChlSab1.1 Ensembl793,317,111 - 93,451,798 (-)Ensembl
Ttc29
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248535,498,697 - 5,709,509 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:733
Count of miRNA genes:419
Interacting mature miRNAs:490
Transcripts:ENSMUST00000049395, ENSMUST00000109902, ENSMUST00000117845, ENSMUST00000124713, ENSMUST00000126172, ENSMUST00000137424, ENSMUST00000143157, ENSMUST00000156432
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000049395   ⟹   ENSMUSP00000041919
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,213,342 - 78,394,326 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109902   ⟹   ENSMUSP00000105528
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,218,794 - 78,393,683 (+)Ensembl
RefSeq Acc Id: ENSMUST00000117845   ⟹   ENSMUSP00000112445
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,213,297 - 78,220,975 (+)Ensembl
RefSeq Acc Id: ENSMUST00000124713
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,390,982 - 78,393,774 (+)Ensembl
RefSeq Acc Id: ENSMUST00000126172   ⟹   ENSMUSP00000122383
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,213,302 - 78,220,833 (+)Ensembl
RefSeq Acc Id: ENSMUST00000137424
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,213,315 - 78,218,018 (+)Ensembl
RefSeq Acc Id: ENSMUST00000143157
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,251,491 - 78,276,829 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156432
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl878,213,350 - 78,217,962 (+)Ensembl
RefSeq Acc Id: NM_183096   ⟹   NP_898919
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39878,939,971 - 79,120,955 (+)NCBI
GRCm38878,213,342 - 78,394,326 (+)NCBI
MGSCv37880,737,241 - 80,918,225 (+)RGD
Celera882,486,892 - 82,670,357 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006531400   ⟹   XP_006531463
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39878,939,911 - 79,120,955 (+)NCBI
GRCm38878,213,282 - 78,394,326 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011248516   ⟹   XP_011246818
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39878,939,911 - 79,120,955 (+)NCBI
GRCm38878,213,282 - 78,394,326 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011248517   ⟹   XP_011246819
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39878,939,911 - 79,120,955 (+)NCBI
GRCm38878,213,282 - 78,394,326 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011248518   ⟹   XP_011246820
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39878,939,911 - 79,120,955 (+)NCBI
GRCm38878,213,282 - 78,394,326 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_898919   ⟸   NM_183096
- UniProtKB: E9QLU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006531463   ⟸   XM_006531400
- Peptide Label: isoform X1
- UniProtKB: E9QLU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246819   ⟸   XM_011248517
- Peptide Label: isoform X1
- UniProtKB: E9QLU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246820   ⟸   XM_011248518
- Peptide Label: isoform X1
- UniProtKB: E9QLU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011246818   ⟸   XM_011248516
- Peptide Label: isoform X1
- UniProtKB: E9QLU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000041919   ⟸   ENSMUST00000049395
RefSeq Acc Id: ENSMUSP00000122383   ⟸   ENSMUST00000126172
RefSeq Acc Id: ENSMUSP00000105528   ⟸   ENSMUST00000109902
RefSeq Acc Id: ENSMUSP00000112445   ⟸   ENSMUST00000117845
Protein Domains
TPR_REGION

Promoters
RGD ID:8667529
Promoter ID:EPDNEW_M11796
Type:initiation region
Name:Ttc29_1
Description:Mus musculus tetratricopeptide repeat domain 29 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38878,213,315 - 78,213,375EPDNEW
RGD ID:6843849
Promoter ID:MM_KWN:54930
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:OTTMUST00000077908
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36880,914,706 - 80,915,206 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920551 AgrOrtholog
Ensembl Genes ENSMUSG00000037101 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000041919 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000105528 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000112445 UniProtKB/Swiss-Prot
  ENSMUSP00000122383 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000049395 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000109902 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000117845 UniProtKB/Swiss-Prot
  ENSMUST00000126172 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TPR-contain_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:73301 UniProtKB/TrEMBL
MGD MGI:1920551 ENTREZGENE
NCBI Gene 73301 ENTREZGENE
PhenoGen Ttc29 PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.61243 ENTREZGENE
UniProt A0A1C7CYV2_MOUSE UniProtKB/TrEMBL
  E9QLU4 ENTREZGENE, UniProtKB/TrEMBL
  Q80VM3 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8CF30 UniProtKB/Swiss-Prot