Tcte1 (t-complex-associated testis expressed 1) - Rat Genome Database

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Gene: Tcte1 (t-complex-associated testis expressed 1) Mus musculus
Analyze
Symbol: Tcte1
Name: t-complex-associated testis expressed 1
RGD ID: 1313959
MGI Page MGI
Description: Involved in flagellated sperm motility. Located in sperm flagellum. Used to study male infertility. Orthologous to human TCTE1 (t-complex-associated-testis-expressed 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D17S; D17Sil1; dynein regulatory complex subunit 5; T-complex-associated testis-expressed protein 1; Tcte-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,834,360 - 45,853,605 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,834,360 - 45,853,606 (+)EnsemblGRCm39 Ensembl
GRCm381745,523,434 - 45,542,679 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,523,434 - 45,542,680 (+)EnsemblGRCm38mm10GRCm38
MGSCv371745,660,383 - 45,679,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361744,996,634 - 45,006,261 (+)NCBIMGSCv36mm8
Celera1748,956,144 - 48,975,339 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci. Nadeau JH, etal., Genomics 1991 Jan;9(1):78-89.
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1543913   PMID:2568335   PMID:2767684   PMID:3653077   PMID:7766998   PMID:8406442   PMID:8889548   PMID:11486276   PMID:12477932   PMID:16141072   PMID:18799693   PMID:21267068  
PMID:21677750   PMID:21873635   PMID:28630322   PMID:30973865   PMID:31961863   PMID:32554934   PMID:38355793   PMID:38650655  


Genomics

Comparative Map Data
Tcte1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391745,834,360 - 45,853,605 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1745,834,360 - 45,853,606 (+)EnsemblGRCm39 Ensembl
GRCm381745,523,434 - 45,542,679 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,523,434 - 45,542,680 (+)EnsemblGRCm38mm10GRCm38
MGSCv371745,660,383 - 45,679,628 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361744,996,634 - 45,006,261 (+)NCBIMGSCv36mm8
Celera1748,956,144 - 48,975,339 (+)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1722.54NCBI
TCTE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38644,278,734 - 44,297,698 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl644,278,734 - 44,297,698 (-)EnsemblGRCh38hg38GRCh38
GRCh37644,246,471 - 44,265,435 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36644,355,880 - 44,373,405 (-)NCBINCBI36Build 36hg18NCBI36
Celera645,801,050 - 45,818,612 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,969,874 - 43,987,548 (-)NCBIHuRef
CHM1_1644,251,609 - 44,269,093 (-)NCBICHM1_1
T2T-CHM13v2.0644,112,859 - 44,131,845 (-)NCBIT2T-CHM13v2.0
Tcte1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,961,005 - 22,979,711 (-)NCBIGRCr8
mRatBN7.2915,463,573 - 15,482,258 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl915,463,739 - 15,472,954 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx924,050,175 - 24,059,500 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0929,112,853 - 29,122,178 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0927,413,615 - 27,422,940 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,847,866 - 17,867,276 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,846,364 - 17,866,927 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0916,736,973 - 16,755,762 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4911,064,068 - 11,073,283 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1911,062,520 - 11,070,536 (-)NCBI
Celera913,206,878 - 13,216,093 (-)NCBICelera
Cytogenetic Map9q12NCBI
Tcte1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,900,301 - 9,908,379 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,900,295 - 9,913,955 (-)NCBIChiLan1.0ChiLan1.0
TCTE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2558,784,133 - 58,801,738 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1654,652,815 - 54,671,821 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,874,469 - 43,894,227 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1645,157,695 - 45,175,956 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl645,154,203 - 45,175,699 (-)Ensemblpanpan1.1panPan2
TCTE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11212,686,459 - 12,704,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1212,687,749 - 12,704,687 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1212,714,686 - 12,732,841 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01213,172,364 - 13,190,526 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1213,173,658 - 13,187,646 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11212,697,791 - 12,715,939 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01212,785,240 - 12,803,394 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,879,460 - 12,897,618 (-)NCBIUU_Cfam_GSD_1.0
Tcte1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494648,153,902 - 48,173,653 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647615,795,358 - 15,804,887 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647615,795,358 - 15,807,563 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCTE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl739,275,950 - 39,299,507 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1739,275,595 - 39,288,326 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2745,145,068 - 45,170,453 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TCTE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11727,870,456 - 27,888,073 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1727,880,057 - 27,888,052 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604444,330,788 - 44,350,987 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tcte1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475415,573,595 - 15,585,760 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475415,574,833 - 15,586,432 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tcte1
710 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:647
Count of miRNA genes:368
Interacting mature miRNAs:454
Transcripts:ENSMUST00000113547
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
4141478Hbnr7_mHeligmosomoides bakeri nematode resistance 7 (mouse)Not determined4305118551739122Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4053444774534623Mouse
26884386Skwq13_mskull length QTL 13, 16 week (mouse)174371089153107028Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174093918774939187Mouse
26884390Skwq9_mskull length QTL 9, 10 week (mouse)174371089167806995Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
25394539Skmw85_mskeletal muscle weight 85, gastroc (mouse)174370766846831957Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
12903997Cfq4_mconditioned fear QTL 4 (mouse)174501655249366402Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
D17Mit35  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381745,542,443 - 45,542,672UniSTSGRCm38
MGSCv371745,679,392 - 45,679,621UniSTSGRCm37
Celera1748,975,103 - 48,975,332UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map17B3UniSTS
cM Map1723.0UniSTS
Whitehead Genetic1714.2UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000113547   ⟹   ENSMUSP00000109175
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1745,834,360 - 45,853,605 (+)Ensembl
GRCm38.p6 Ensembl1745,523,434 - 45,542,679 (+)Ensembl
Ensembl Acc Id: ENSMUST00000233588   ⟹   ENSMUSP00000156920
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1745,843,979 - 45,853,606 (+)Ensembl
GRCm38.p6 Ensembl1745,533,053 - 45,542,680 (+)Ensembl
RefSeq Acc Id: NM_013688   ⟹   NP_038716
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391745,834,360 - 45,853,605 (+)NCBI
GRCm381745,523,434 - 45,542,679 (+)ENTREZGENE
MGSCv371745,660,383 - 45,679,628 (+)RGD
Celera1748,956,144 - 48,975,339 (+)RGD
cM Map17 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_038716 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A6H639 (Get FASTA)   NCBI Sequence Viewer  
  AAA40406 (Get FASTA)   NCBI Sequence Viewer  
  AAI45742 (Get FASTA)   NCBI Sequence Viewer  
  EDL23442 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000109175
  ENSMUSP00000109175.2
  ENSMUSP00000156920.2
RefSeq Acc Id: NP_038716   ⟸   NM_013688
- UniProtKB: Q62294 (UniProtKB/Swiss-Prot),   A6H639 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000109175   ⟸   ENSMUST00000113547
Ensembl Acc Id: ENSMUSP00000156920   ⟸   ENSMUST00000233588

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6H639-F1-model_v2 AlphaFold A6H639 1-498 view protein structure

Promoters
RGD ID:13676156
Promoter ID:EPDNEW_M22227
Type:multiple initiation site
Name:Tcte1_1
Description:Mus musculus t-complex-associated testis expressed 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381745,523,425 - 45,523,485EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98640 AgrOrtholog
Ensembl Genes ENSMUSG00000023949 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000113547 ENTREZGENE
  ENSMUST00000113547.2 UniProtKB/Swiss-Prot
  ENSMUST00000233588.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot
InterPro DRC5 UniProtKB/Swiss-Prot
  Leu-rich_rpt UniProtKB/Swiss-Prot
  LRR_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:21645 UniProtKB/Swiss-Prot
MGD MGI:98640 ENTREZGENE
NCBI Gene 21645 ENTREZGENE
PANTHER DYNEIN REGULATORY COMPLEX SUBUNIT 5 UniProtKB/Swiss-Prot
  YNEIN REGULATORY COMPLEX SUBUNIT 5 UniProtKB/Swiss-Prot
Pfam LRR_6 UniProtKB/Swiss-Prot
PhenoGen Tcte1 PhenoGen
SMART LRR_RI UniProtKB/Swiss-Prot
Superfamily-SCOP RNI-like UniProtKB/Swiss-Prot
UniProt A6H639 ENTREZGENE, UniProtKB/Swiss-Prot
  Q62294 ENTREZGENE
  Q62295_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q62294 UniProtKB/Swiss-Prot