Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | SENP7 | Human | (+)-schisandrin B | multiple interactions | ISO | Senp7 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SENP7 mRNA] | CTD | PMID:31150632 | SENP7 | Human | (-)-epigallocatechin 3-gallate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SENP7 mRNA | CTD | PMID:22079256 | SENP7 | Human | 1,2-dimethylhydrazine | decreases expression | ISO | Senp7 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SENP7 mRNA | CTD | PMID:22206623 | SENP7 | Human | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of SENP7 mRNA | CTD | PMID:22574217 | SENP7 | Human | 17beta-estradiol | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of SENP7 mRNA | CTD | PMID:32145629 | SENP7 | Human | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Senp7 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SENP7 mRNA | CTD | PMID:21354282 | SENP7 | Human | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Senp7 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SENP7 mRNA | CTD | PMID:21570461 | SENP7 | Human | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SENP7 mRNA | CTD | PMID:21215274 | SENP7 | Human | 6-propyl-2-thiouracil | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of SENP7 mRNA | CTD | PMID:30047161 | SENP7 | Human | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of SENP7 mRNA | CTD | PMID:32763439 | SENP7 | Human | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of SENP7 mRNA | CTD | PMID:22100608 | SENP7 | Human | aflatoxin M1 | decreases expression | EXP | | 6480464 | Aflatoxin M1 results in decreased expression of SENP7 mRNA | CTD | PMID:30928695 | SENP7 | Human | amitrole | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of SENP7 mRNA | CTD | PMID:30047161 | SENP7 | Human | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of SENP7 mRNA | CTD | PMID:33212167 | SENP7 | Human | benzo[a]pyrene | increases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Benzo(a)pyrene results in increased expression of SENP7 mRNA | CTD | PMID:21839799 | SENP7 | Human | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of SENP7 promoter | CTD | PMID:27901495 | SENP7 | Human | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of SENP7 mRNA | CTD | PMID:20106945 more ... | SENP7 | Human | benzo[a]pyrene | affects expression | EXP | | 6480464 | Benzo(a)pyrene affects the expression of SENP7 mRNA | CTD | PMID:21714911 | SENP7 | Human | bisphenol A | affects expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SENP7 mRNA | CTD | PMID:25181051 | SENP7 | Human | bisphenol A | increases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SENP7 mRNA | CTD | PMID:33296240 | SENP7 | Human | bisphenol A | increases methylation | ISO | Senp7 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of SENP7 gene | CTD | PMID:28505145 | SENP7 | Human | chlorpyrifos | decreases expression | ISO | Senp7 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of SENP7 mRNA | CTD | PMID:20350560 | SENP7 | Human | chromium(6+) | decreases expression | EXP | | 6480464 | chromium hexavalent ion results in decreased expression of SENP7 mRNA | CTD | PMID:27793765 | SENP7 | Human | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of SENP7 mRNA | CTD | PMID:27392435 | SENP7 | Human | cisplatin | multiple interactions | EXP | | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of SENP7 mRNA | CTD | PMID:27392435 | SENP7 | Human | clorgyline | increases expression | EXP | | 6480464 | Clorgyline results in increased expression of SENP7 mRNA | CTD | PMID:19691856 | SENP7 | Human | clotrimazole | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Clotrimazole results in decreased expression of SENP7 mRNA | CTD | PMID:30047161 | SENP7 | Human | crocidolite asbestos | decreases expression | ISO | Senp7 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of SENP7 mRNA | CTD | PMID:29279043 | SENP7 | Human | Dibutyl phosphate | affects expression | EXP | | 6480464 | di-n-butylphosphoric acid affects the expression of SENP7 mRNA | CTD | PMID:37042841 | SENP7 | Human | dicrotophos | decreases expression | EXP | | 6480464 | dicrotophos results in decreased expression of SENP7 mRNA | CTD | PMID:28302478 | SENP7 | Human | diquat | decreases expression | ISO | Senp7 (Mus musculus) | 6480464 | Diquat results in decreased expression of SENP7 protein | CTD | PMID:36851058 | SENP7 | Human | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SENP7 mRNA | CTD | PMID:27188386 | SENP7 | Human | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of SENP7 mRNA | CTD | PMID:29803840 | SENP7 | Human | entinostat | decreases expression | EXP | | 6480464 | entinostat results in decreased expression of SENP7 mRNA | CTD | PMID:26272509 | SENP7 | Human | entinostat | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SENP7 mRNA | CTD | PMID:27188386 | SENP7 | Human | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of SENP7 mRNA | CTD | PMID:21867686 | SENP7 | Human | FR900359 | decreases phosphorylation | EXP | | 6480464 | FR900359 results in decreased phosphorylation of SENP7 protein | CTD | PMID:37730182 | SENP7 | Human | gentamycin | increases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of SENP7 mRNA | CTD | PMID:22061828 | SENP7 | Human | ketamine | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Ketamine results in decreased expression of SENP7 mRNA | CTD | PMID:20080153 | SENP7 | Human | methimazole | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of SENP7 mRNA | CTD | PMID:30047161 | SENP7 | Human | methyl methanesulfonate | increases expression | EXP | | 6480464 | Methyl Methanesulfonate results in increased expression of SENP7 mRNA | CTD | PMID:23649840 | SENP7 | Human | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of SENP7 mRNA | CTD | PMID:28001369 | SENP7 | Human | oxaliplatin | multiple interactions | ISO | Senp7 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of SENP7 mRNA | CTD | PMID:25729387 | SENP7 | Human | paracetamol | affects expression | ISO | Senp7 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SENP7 mRNA | CTD | PMID:17562736 | SENP7 | Human | paracetamol | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of SENP7 mRNA | CTD | PMID:33387578 | SENP7 | Human | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SENP7 mRNA | CTD | PMID:29067470 | SENP7 | Human | pentanal | decreases expression | EXP | | 6480464 | pentanal results in decreased expression of SENP7 mRNA | CTD | PMID:26079696 | SENP7 | Human | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of SENP7 mRNA | CTD | PMID:27153767 | SENP7 | Human | phenobarbital | affects expression | ISO | Senp7 (Mus musculus) | 6480464 | Phenobarbital affects the expression of SENP7 mRNA | CTD | PMID:23091169 | SENP7 | Human | phenytoin | increases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Phenytoin results in increased expression of SENP7 mRNA | CTD | PMID:20345932 | SENP7 | Human | pirinixic acid | multiple interactions | ISO | Senp7 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SENP7 mRNA | CTD | PMID:19710929 | SENP7 | Human | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of SENP7 mRNA | CTD | PMID:22079256 | SENP7 | Human | potassium chromate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SENP7 mRNA | CTD | PMID:22079256 | SENP7 | Human | quercetin | decreases expression | EXP | | 6480464 | Quercetin results in decreased expression of SENP7 mRNA | CTD | PMID:21632981 | SENP7 | Human | resveratrol | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | resveratrol results in decreased expression of SENP7 mRNA | CTD | PMID:25905778 | SENP7 | Human | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SENP7 mRNA | CTD | PMID:23557933 | SENP7 | Human | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SENP7 mRNA | CTD | PMID:27188386 | SENP7 | Human | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of SENP7 mRNA | CTD | PMID:34973136 | SENP7 | Human | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of SENP7 mRNA | CTD | PMID:28595984 and PMID:34032870 | SENP7 | Human | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of SENP7 mRNA | CTD | PMID:38568856 | SENP7 | Human | sodium dichromate | affects expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | sodium bichromate affects the expression of SENP7 mRNA | CTD | PMID:22110744 | SENP7 | Human | succimer | multiple interactions | ISO | Senp7 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SENP7 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of SENP7 mRNA | CTD | PMID:21641980 and PMID:26378955 | SENP7 | Human | sulfadimethoxine | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of SENP7 mRNA | CTD | PMID:30047161 | SENP7 | Human | sunitinib | increases expression | EXP | | 6480464 | Sunitinib results in increased expression of SENP7 mRNA | CTD | PMID:31533062 | SENP7 | Human | tetrachloromethane | multiple interactions | ISO | Senp7 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SENP7 mRNA] | CTD | PMID:31150632 | SENP7 | Human | tetrachloromethane | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of SENP7 mRNA | CTD | PMID:31150632 | SENP7 | Human | thapsigargin | increases expression | ISO | Senp7 (Mus musculus) | 6480464 | Thapsigargin results in increased expression of SENP7 protein | CTD | PMID:24648495 | SENP7 | Human | thimerosal | increases expression | EXP | | 6480464 | Thimerosal results in increased expression of SENP7 mRNA | CTD | PMID:27188386 | SENP7 | Human | thioacetamide | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of SENP7 mRNA | CTD | PMID:34492290 | SENP7 | Human | titanium dioxide | increases methylation | ISO | Senp7 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of SENP7 gene | CTD | PMID:35295148 | SENP7 | Human | topotecan | decreases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | Topotecan results in decreased expression of SENP7 mRNA | CTD | PMID:25729387 | SENP7 | Human | topotecan | multiple interactions | ISO | Senp7 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of SENP7 mRNA | CTD | PMID:25729387 | SENP7 | Human | triptonide | affects expression | ISO | Senp7 (Mus musculus) | 6480464 | triptonide affects the expression of SENP7 mRNA | CTD | PMID:33045310 | SENP7 | Human | troglitazone | decreases expression | ISO | Senp7 (Mus musculus) | 6480464 | troglitazone results in decreased expression of SENP7 mRNA | CTD | PMID:28973697 | SENP7 | Human | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of SENP7 mRNA | CTD | PMID:23179753 and PMID:27188386 | SENP7 | Human | vinclozolin | increases expression | ISO | Senp7 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of SENP7 mRNA | CTD | PMID:23034163 | SENP7 | Human | zinc atom | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of SENP7 mRNA | CTD | PMID:22171008 | SENP7 | Human | zinc(0) | decreases expression | EXP | | 6480464 | Zinc deficiency results in decreased expression of SENP7 mRNA | CTD | PMID:22171008 | |