SENP7 (SUMO specific peptidase 7) - Rat Genome Database

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Gene: SENP7 (SUMO specific peptidase 7) Homo sapiens
Analyze
Symbol: SENP7
Name: SUMO specific peptidase 7
RGD ID: 1313579
HGNC Page HGNC:30402
Description: Predicted to enable SUMO-specific endopeptidase activity. Predicted to be involved in antiviral innate immune response and protein desumoylation. Located in nucleus.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: KIAA1707; MGC157730; sentrin-specific protease 7; sentrin/SUMO-specific protease SENP7; SUMO-1-specific protease 2; SUMO1/sentrin specific peptidase 7; SUMO1/sentrin specific protease 7
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383101,324,205 - 101,513,212 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3101,324,205 - 101,513,241 (-)EnsemblGRCh38hg38GRCh38
GRCh373101,043,049 - 101,232,056 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363102,525,807 - 102,714,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 343102,525,811 - 102,714,775NCBI
Celera399,434,719 - 99,624,210 (-)NCBICelera
Cytogenetic Map3q12.3NCBI
HuRef398,411,695 - 98,600,626 (-)NCBIHuRef
CHM1_13101,006,076 - 101,195,158 (-)NCBICHM1_1
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISS)
nucleus  (IBA,IDA)
postsynaptic cytosol  (IEA,ISO)
presynaptic cytosol  (IEA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10652325   PMID:11076863   PMID:11214970   PMID:11230166   PMID:11256614   PMID:12477932   PMID:15489336   PMID:16147992   PMID:16381901   PMID:17081983   PMID:18799455   PMID:20562864  
PMID:21873635   PMID:21878624   PMID:23045645   PMID:24018422   PMID:25895136   PMID:26354767   PMID:27705803   PMID:28429743   PMID:28514442   PMID:28986522   PMID:29298432   PMID:29777712  
PMID:30021884   PMID:31753913   PMID:31825833   PMID:32393512   PMID:33187986   PMID:33961781   PMID:34079125   PMID:35143421   PMID:35271311   PMID:36089195   PMID:38334954  


Genomics

Comparative Map Data
SENP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383101,324,205 - 101,513,212 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3101,324,205 - 101,513,241 (-)EnsemblGRCh38hg38GRCh38
GRCh373101,043,049 - 101,232,056 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363102,525,807 - 102,714,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 343102,525,811 - 102,714,775NCBI
Celera399,434,719 - 99,624,210 (-)NCBICelera
Cytogenetic Map3q12.3NCBI
HuRef398,411,695 - 98,600,626 (-)NCBIHuRef
CHM1_13101,006,076 - 101,195,158 (-)NCBICHM1_1
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBIT2T-CHM13v2.0
Senp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391655,869,306 - 56,010,394 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1655,868,701 - 56,010,375 (+)EnsemblGRCm39 Ensembl
GRCm381656,057,526 - 56,190,031 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1656,048,338 - 56,190,012 (+)EnsemblGRCm38mm10GRCm38
MGSCv371656,075,522 - 56,190,124 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361656,000,360 - 56,114,962 (+)NCBIMGSCv36mm8
Celera1656,384,282 - 56,499,373 (+)NCBICelera
Cytogenetic Map16C1.1NCBI
cM Map1633.82NCBI
Senp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81157,892,801 - 58,053,213 (-)NCBIGRCr8
mRatBN7.21144,423,733 - 44,584,129 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1144,423,735 - 44,564,711 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1153,200,757 - 53,341,107 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01145,862,371 - 46,002,722 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01144,986,531 - 45,126,884 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01146,880,928 - 47,047,052 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1146,880,928 - 47,027,667 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01150,062,235 - 50,210,519 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41145,390,458 - 45,539,624 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11145,448,065 - 45,596,923 (-)NCBI
Celera1144,175,376 - 44,315,364 (-)NCBICelera
Cytogenetic Map11q12NCBI
Senp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554272,924,108 - 3,092,020 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554272,925,159 - 3,091,932 (-)NCBIChiLan1.0ChiLan1.0
SENP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2299,269,721 - 99,471,316 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1399,274,502 - 99,475,372 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0398,422,018 - 98,623,832 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13105,101,733 - 105,302,921 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3105,103,473 - 105,283,838 (-)Ensemblpanpan1.1panPan2
SENP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1337,787,910 - 7,927,679 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl337,787,910 - 7,927,550 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha337,942,370 - 8,082,059 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0337,926,759 - 8,066,944 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl337,926,788 - 8,066,929 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1337,815,014 - 7,954,343 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0337,860,814 - 8,000,503 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0338,200,385 - 8,340,979 (-)NCBIUU_Cfam_GSD_1.0
Senp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602148,942,864 - 149,080,606 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366301,840,732 - 1,979,060 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366301,840,761 - 1,978,500 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SENP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13157,521,784 - 157,672,814 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113157,521,778 - 157,672,818 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213166,985,019 - 167,153,326 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SENP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12279,372,335 - 79,557,319 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2279,462,837 - 79,557,871 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604186,999,541 - 87,191,689 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Senp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478915,182,645 - 15,397,045 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478915,182,709 - 15,397,642 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SENP7
70 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3q11.1-21.1(chr3:93886671-123216683)x1 copy number loss See cases [RCV000051543] Chr3:93886671..123216683 [GRCh38]
Chr3:93605515..122935530 [GRCh37]
Chr3:95088205..124418220 [NCBI36]
Chr3:3q11.1-21.1
pathogenic
GRCh38/hg38 3q11.1-13.31(chr3:93819623-116887056)x1 copy number loss See cases [RCV000135320] Chr3:93819623..116887056 [GRCh38]
Chr3:93538467..116605903 [GRCh37]
Chr3:95021157..118088593 [NCBI36]
Chr3:3q11.1-13.31
pathogenic
GRCh38/hg38 3q11.2-13.31(chr3:97795369-115663349)x1 copy number loss See cases [RCV000138186] Chr3:97795369..115663349 [GRCh38]
Chr3:97514213..115382196 [GRCh37]
Chr3:98996903..116864886 [NCBI36]
Chr3:3q11.2-13.31
pathogenic|uncertain significance
GRCh38/hg38 3q11.1-24(chr3:93800620-145695381)x3 copy number gain See cases [RCV000142340] Chr3:93800620..145695381 [GRCh38]
Chr3:93519464..145413168 [GRCh37]
Chr3:95002154..146895858 [NCBI36]
Chr3:3q11.1-24
pathogenic
GRCh38/hg38 3q12.2-12.3(chr3:100828503-101465000)x1 copy number loss See cases [RCV000143146] Chr3:100828503..101465000 [GRCh38]
Chr3:100547347..101183844 [GRCh37]
Chr3:102030037..102666534 [NCBI36]
Chr3:3q12.2-12.3
uncertain significance
GRCh38/hg38 3q11.1-13.11(chr3:93819623-103888749)x3 copy number gain See cases [RCV000143259] Chr3:93819623..103888749 [GRCh38]
Chr3:93538467..103607593 [GRCh37]
Chr3:95021157..105090283 [NCBI36]
Chr3:3q11.1-13.11
likely pathogenic|uncertain significance
NM_020654.5(SENP7):c.3105G>T (p.Glu1035Asp) single nucleotide variant not specified [RCV004287988] Chr3:101325991 [GRCh38]
Chr3:101044835 [GRCh37]
Chr3:3q12.3
uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
NM_020654.5(SENP7):c.1475A>G (p.Gln492Arg) single nucleotide variant not specified [RCV004332850] Chr3:101364835 [GRCh38]
Chr3:101083679 [GRCh37]
Chr3:3q12.3
uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29
pathogenic
GRCh37/hg19 3q12.2-13.13(chr3:100613996-108976446)x3 copy number gain not provided [RCV000742661] Chr3:100613996..108976446 [GRCh37]
Chr3:3q12.2-13.13
likely pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29
pathogenic
NM_020654.5(SENP7):c.284+6A>C single nucleotide variant not provided [RCV000958679] Chr3:101458949 [GRCh38]
Chr3:101177793 [GRCh37]
Chr3:3q12.3
benign
NM_020654.5(SENP7):c.724A>T (p.Thr242Ser) single nucleotide variant not provided [RCV000884430] Chr3:101372080 [GRCh38]
Chr3:101090924 [GRCh37]
Chr3:3q12.3
benign
NM_020654.5(SENP7):c.723G>T (p.Gln241His) single nucleotide variant not provided [RCV000884431] Chr3:101372081 [GRCh38]
Chr3:101090925 [GRCh37]
Chr3:3q12.3
benign
NM_020654.5(SENP7):c.277C>T (p.Pro93Ser) single nucleotide variant not specified [RCV004319664] Chr3:101458962 [GRCh38]
Chr3:101177806 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.923A>G (p.Asn308Ser) single nucleotide variant not provided [RCV000905976] Chr3:101367885 [GRCh38]
Chr3:101086729 [GRCh37]
Chr3:3q12.3
benign
NM_020654.5(SENP7):c.1909G>T (p.Asp637Tyr) single nucleotide variant not provided [RCV000961446] Chr3:101343883 [GRCh38]
Chr3:101062727 [GRCh37]
Chr3:3q12.3
benign
NM_020654.5(SENP7):c.402A>G (p.Ser134=) single nucleotide variant not provided [RCV000956116] Chr3:101417673 [GRCh38]
Chr3:101136517 [GRCh37]
Chr3:3q12.3
benign
GRCh37/hg19 3q11.2-12.3(chr3:95563096-102371126)x1 copy number loss not provided [RCV001259224] Chr3:95563096..102371126 [GRCh37]
Chr3:3q11.2-12.3
likely pathogenic
GRCh37/hg19 3q12.3(chr3:101191611-101938521) copy number gain not specified [RCV002053365] Chr3:101191611..101938521 [GRCh37]
Chr3:3q12.3
uncertain significance
NC_000003.11:g.(?_100945813)_(101484395_?)del deletion not provided [RCV001926522] Chr3:100945813..101484395 [GRCh37]
Chr3:3q12.3
pathogenic
NC_000003.11:g.(?_100945813)_(101284837_?)dup duplication not provided [RCV002010565] Chr3:100945813..101284837 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.3078A>G (p.Ile1026Met) single nucleotide variant not specified [RCV004329779] Chr3:101326018 [GRCh38]
Chr3:101044862 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.622A>G (p.Ser208Gly) single nucleotide variant not specified [RCV004307832] Chr3:101398916 [GRCh38]
Chr3:101117760 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2350T>C (p.Tyr784His) single nucleotide variant not specified [RCV004110648] Chr3:101340102 [GRCh38]
Chr3:101058946 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2117C>T (p.Thr706Ile) single nucleotide variant not specified [RCV004140490] Chr3:101341769 [GRCh38]
Chr3:101060613 [GRCh37]
Chr3:3q12.3
likely benign
NM_020654.5(SENP7):c.245T>C (p.Ile82Thr) single nucleotide variant not specified [RCV004136684] Chr3:101458994 [GRCh38]
Chr3:101177838 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.149A>C (p.Lys50Thr) single nucleotide variant not specified [RCV004086977] Chr3:101493910 [GRCh38]
Chr3:101212754 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.971A>G (p.Glu324Gly) single nucleotide variant not specified [RCV004084983] Chr3:101367837 [GRCh38]
Chr3:101086681 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2711G>A (p.Arg904His) single nucleotide variant not specified [RCV004225298] Chr3:101330374 [GRCh38]
Chr3:101049218 [GRCh37]
Chr3:3q12.3
likely benign
NM_020654.5(SENP7):c.582C>G (p.Asp194Glu) single nucleotide variant not specified [RCV004100900] Chr3:101398956 [GRCh38]
Chr3:101117800 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.3067C>T (p.Arg1023Cys) single nucleotide variant not specified [RCV004100058] Chr3:101326029 [GRCh38]
Chr3:101044873 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.413C>A (p.Thr138Lys) single nucleotide variant not specified [RCV004121367] Chr3:101417662 [GRCh38]
Chr3:101136506 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2366T>C (p.Ile789Thr) single nucleotide variant not specified [RCV004138054] Chr3:101337623 [GRCh38]
Chr3:101056467 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2222A>T (p.His741Leu) single nucleotide variant not specified [RCV004131843] Chr3:101341664 [GRCh38]
Chr3:101060508 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1478T>G (p.Met493Arg) single nucleotide variant not specified [RCV004121559] Chr3:101361860 [GRCh38]
Chr3:101080704 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2104C>A (p.Gln702Lys) single nucleotide variant not specified [RCV004118911] Chr3:101343688 [GRCh38]
Chr3:101062532 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1391A>C (p.Gln464Pro) single nucleotide variant not specified [RCV004226424] Chr3:101364919 [GRCh38]
Chr3:101083763 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2769G>A (p.Met923Ile) single nucleotide variant not specified [RCV004190149] Chr3:101328672 [GRCh38]
Chr3:101047516 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1205T>C (p.Ile402Thr) single nucleotide variant not specified [RCV004171200] Chr3:101366543 [GRCh38]
Chr3:101085387 [GRCh37]
Chr3:3q12.3
likely benign
NM_020654.5(SENP7):c.1739A>T (p.His580Leu) single nucleotide variant not specified [RCV004175165] Chr3:101347970 [GRCh38]
Chr3:101066814 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.641A>C (p.Asn214Thr) single nucleotide variant not specified [RCV004122560] Chr3:101398897 [GRCh38]
Chr3:101117741 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.746G>A (p.Arg249Gln) single nucleotide variant not specified [RCV004205892] Chr3:101372058 [GRCh38]
Chr3:101090902 [GRCh37]
Chr3:3q12.3
likely benign
NM_020654.5(SENP7):c.2167T>C (p.Cys723Arg) single nucleotide variant not specified [RCV004179516] Chr3:101341719 [GRCh38]
Chr3:101060563 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2048G>A (p.Cys683Tyr) single nucleotide variant not specified [RCV004129880] Chr3:101343744 [GRCh38]
Chr3:101062588 [GRCh37]
Chr3:3q12.3
likely benign
NM_020654.5(SENP7):c.410C>T (p.Ser137Leu) single nucleotide variant not specified [RCV004150729] Chr3:101417665 [GRCh38]
Chr3:101136509 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.84A>T (p.Leu28Phe) single nucleotide variant not specified [RCV004131672] Chr3:101501076 [GRCh38]
Chr3:101219920 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1474C>T (p.Gln492Ter) single nucleotide variant arthrogryposis multiplex congenita with neutropenia and early respiratory failure [RCV003226605] Chr3:101364836 [GRCh38]
Chr3:101083680 [GRCh37]
Chr3:3q12.3
likely pathogenic
NM_020654.5(SENP7):c.2710C>T (p.Arg904Cys) single nucleotide variant not specified [RCV004250924] Chr3:101330375 [GRCh38]
Chr3:101049219 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2224A>G (p.Thr742Ala) single nucleotide variant not specified [RCV004270457] Chr3:101341662 [GRCh38]
Chr3:101060506 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.691A>G (p.Ser231Gly) single nucleotide variant not specified [RCV004264473] Chr3:101372113 [GRCh38]
Chr3:101090957 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2540A>G (p.Asn847Ser) single nucleotide variant not specified [RCV004263670] Chr3:101332803 [GRCh38]
Chr3:101051647 [GRCh37]
Chr3:3q12.3
uncertain significance
GRCh38/hg38 3q11.1-21.2(chr3:93979547-124774010)x1 copy number loss Chromosome 3q13.31 deletion syndrome [RCV003327614] Chr3:93979547..124774010 [GRCh38]
Chr3:3q11.1-21.2
pathogenic
NM_020654.5(SENP7):c.990A>C (p.Glu330Asp) single nucleotide variant not specified [RCV004345622] Chr3:101366758 [GRCh38]
Chr3:101085602 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.802A>G (p.Asn268Asp) single nucleotide variant not specified [RCV004351345] Chr3:101368006 [GRCh38]
Chr3:101086850 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1024C>T (p.Pro342Ser) single nucleotide variant not specified [RCV004348217] Chr3:101366724 [GRCh38]
Chr3:101085568 [GRCh37]
Chr3:3q12.3
likely benign
NM_020654.5(SENP7):c.83T>C (p.Leu28Ser) single nucleotide variant not specified [RCV004341320] Chr3:101501077 [GRCh38]
Chr3:101219921 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.305C>T (p.Thr102Met) single nucleotide variant not specified [RCV004334820] Chr3:101417770 [GRCh38]
Chr3:101136614 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1569A>G (p.Ile523Met) single nucleotide variant not specified [RCV004358027] Chr3:101361769 [GRCh38]
Chr3:101080613 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2693C>T (p.Thr898Ile) single nucleotide variant not specified [RCV004343994] Chr3:101331990 [GRCh38]
Chr3:101050834 [GRCh37]
Chr3:3q12.3
uncertain significance
GRCh37/hg19 3q12.3(chr3:100947511-101244028)x3 copy number gain not provided [RCV003484139] Chr3:100947511..101244028 [GRCh37]
Chr3:3q12.3
uncertain significance
GRCh37/hg19 3q11.1-12.3(chr3:93519465-101464485)x3 copy number gain not specified [RCV003986472] Chr3:93519465..101464485 [GRCh37]
Chr3:3q11.1-12.3
uncertain significance
GRCh37/hg19 3q12.2-13.11(chr3:100369522-104621416)x1 copy number loss not specified [RCV003986403] Chr3:100369522..104621416 [GRCh37]
Chr3:3q12.2-13.11
uncertain significance
NM_020654.5(SENP7):c.1234G>A (p.Asp412Asn) single nucleotide variant not specified [RCV004450822] Chr3:101366514 [GRCh38]
Chr3:101085358 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1256T>C (p.Ile419Thr) single nucleotide variant not specified [RCV004450823] Chr3:101366492 [GRCh38]
Chr3:101085336 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.192A>C (p.Glu64Asp) single nucleotide variant not specified [RCV004450825] Chr3:101459047 [GRCh38]
Chr3:101177891 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2957A>G (p.Gln986Arg) single nucleotide variant not specified [RCV004450828] Chr3:101327724 [GRCh38]
Chr3:101046568 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.436T>C (p.Cys146Arg) single nucleotide variant not specified [RCV004450829] Chr3:101417639 [GRCh38]
Chr3:101136483 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2819C>T (p.Ser940Phe) single nucleotide variant not specified [RCV004450827] Chr3:101328523 [GRCh38]
Chr3:101047367 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.463A>C (p.Ser155Arg) single nucleotide variant not specified [RCV004450830] Chr3:101417612 [GRCh38]
Chr3:101136456 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1888A>G (p.Arg630Gly) single nucleotide variant not specified [RCV004450824] Chr3:101343904 [GRCh38]
Chr3:101062748 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.1965G>T (p.Leu655Phe) single nucleotide variant not specified [RCV004450826] Chr3:101343827 [GRCh38]
Chr3:101062671 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2720C>T (p.Ser907Leu) single nucleotide variant not specified [RCV004667104] Chr3:101330365 [GRCh38]
Chr3:101049209 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.497T>C (p.Ile166Thr) single nucleotide variant not specified [RCV004663898] Chr3:101399041 [GRCh38]
Chr3:101117885 [GRCh37]
Chr3:3q12.3
uncertain significance
NC_000003.11:g.(?_99509527)_(101484395_?)del deletion not provided [RCV004582326] Chr3:99509527..101484395 [GRCh37]
Chr3:3q12.1-12.3
uncertain significance
NM_020654.5(SENP7):c.2834C>G (p.Ser945Cys) single nucleotide variant not specified [RCV004663894] Chr3:101328508 [GRCh38]
Chr3:101047352 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2642A>G (p.Gln881Arg) single nucleotide variant not specified [RCV004663897] Chr3:101332041 [GRCh38]
Chr3:101050885 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.2065G>A (p.Val689Ile) single nucleotide variant not specified [RCV004663895] Chr3:101343727 [GRCh38]
Chr3:101062571 [GRCh37]
Chr3:3q12.3
uncertain significance
NM_020654.5(SENP7):c.458G>A (p.Arg153His) single nucleotide variant not specified [RCV004663896] Chr3:101417617 [GRCh38]
Chr3:101136461 [GRCh37]
Chr3:3q12.3
likely benign
NM_020654.5(SENP7):c.3088C>T (p.Arg1030Trp) single nucleotide variant Arthrogryposis multiplex congenita [RCV004720223] Chr3:101326008 [GRCh38]
Chr3:101044852 [GRCh37]
Chr3:3q12.3
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3002
Count of miRNA genes:671
Interacting mature miRNAs:728
Transcripts:ENST00000314261, ENST00000348610, ENST00000358203, ENST00000366089, ENST00000394085, ENST00000394091, ENST00000394094, ENST00000394095, ENST00000460107
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407334919GWAS983895_Herythrocyte count QTL GWAS983895 (human)4e-10erythrocyte countred blood cell count (CMO:0000025)3101417558101417559Human
407246982GWAS895958_Haspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement QTL GWAS895958 (human)5e-12aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurementblood high density lipoprotein cholesterol level (CMO:0000052)3101417558101417559Human
406894976GWAS543952_Halpha fetoprotein measurement QTL GWAS543952 (human)1e-59blood alpha-fetoprotein amount (VT:0010776)3101428128101428129Human
407409482GWAS1058458_Hdiastolic blood pressure QTL GWAS1058458 (human)3e-08diastolic blood pressurediastolic blood pressure (CMO:0000005)3101492643101492644Human
407290245GWAS939221_Hbody height QTL GWAS939221 (human)2e-42body height (VT:0001253)body height (CMO:0000106)3101417558101417559Human
407108231GWAS757207_Herythrocyte count QTL GWAS757207 (human)5e-13erythrocyte countred blood cell count (CMO:0000025)3101417558101417559Human
407032452GWAS681428_Hplatelet count QTL GWAS681428 (human)9e-13platelet quantity (VT:0003179)platelet count (CMO:0000029)3101390336101390337Human
407321857GWAS970833_HIGF-1 measurement QTL GWAS970833 (human)2e-09IGF-1 measurementblood insulin-like growth factor 1 level (CMO:0001297)3101508108101508109Human
407368079GWAS1017055_Halkaline phosphatase measurement QTL GWAS1017055 (human)2e-20alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)3101365760101365761Human
407352079GWAS1001055_HBMI-adjusted waist-hip ratio QTL GWAS1001055 (human)1e-08BMI-adjusted waist-hip ratio3101365760101365761Human
406941961GWAS590937_Hlate-onset Alzheimers disease QTL GWAS590937 (human)0.000004late-onset Alzheimers disease3101508591101508592Human
407161098GWAS810074_Hbody mass index QTL GWAS810074 (human)3e-08body mass indexbody mass index (BMI) (CMO:0000105)3101324976101324977Human
407045900GWAS694876_Hplatelet count QTL GWAS694876 (human)4e-15platelet quantity (VT:0003179)platelet count (CMO:0000029)3101420367101420368Human
406927057GWAS576033_Happendicular lean mass QTL GWAS576033 (human)5e-10appendicular lean mass3101469554101469555Human
407044051GWAS693027_Hred blood cell density measurement QTL GWAS693027 (human)3e-17red blood cell density measurement3101417558101417559Human
407107793GWAS756769_Hplatelet crit QTL GWAS756769 (human)2e-12platelet critplateletcrit (CMO:0001349)3101401096101401097Human
407392347GWAS1041323_Halkaline phosphatase measurement QTL GWAS1041323 (human)4e-17alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)3101365760101365761Human
407083792GWAS732768_Hmosaic loss of chromosome Y measurement QTL GWAS732768 (human)6e-44mosaic loss of chromosome Y measurement3101415852101415853Human
407390430GWAS1039406_HBMI-adjusted waist-hip ratio QTL GWAS1039406 (human)5e-09BMI-adjusted waist-hip ratio3101365760101365761Human
407014036GWAS663012_Hprotein measurement QTL GWAS663012 (human)6e-09protein measurement3101403471101403472Human
407322641GWAS971617_Hrisk-taking behaviour QTL GWAS971617 (human)1e-11risk-taking behaviour3101462406101462407Human
407170524GWAS819500_Hbody fat percentage QTL GWAS819500 (human)4e-11body fat percentagebody fat percentage (CMO:0000302)3101417558101417559Human
407114460GWAS763436_Halcohol consumption measurement QTL GWAS763436 (human)1e-08alcohol consumption measurementethanol drink intake rate (CMO:0001407)3101487319101487320Human
406984665GWAS633641_Hbitter alcoholic beverage consumption measurement QTL GWAS633641 (human)0.000008bitter alcoholic beverage consumption measurementdrink intake measurement (CMO:0000771)3101462406101462407Human
407394388GWAS1043364_Hserum gamma-glutamyl transferase measurement QTL GWAS1043364 (human)3e-10serum gamma-glutamyl transferase measurementserum gamma-glutamyltransferase activity level (CMO:0002241)3101365760101365761Human
407360089GWAS1009065_Hmyeloproliferative disorder QTL GWAS1009065 (human)4e-11myeloproliferative disorder3101479760101479761Human
407103452GWAS752428_Hmean corpuscular hemoglobin QTL GWAS752428 (human)1e-16mean corpuscular hemoglobinmean corpuscular hemoglobin (CMO:0000290)3101417558101417559Human
407183525GWAS832501_Hmemory performance QTL GWAS832501 (human)0.0000002memory performance3101351354101351355Human
407084065GWAS733041_Hmosaic loss of chromosome Y measurement QTL GWAS733041 (human)8e-19mosaic loss of chromosome Y measurement3101415852101415853Human
406919141GWAS568117_Hrisk-taking behaviour QTL GWAS568117 (human)4e-12risk-taking behaviour3101462406101462407Human
407111084GWAS760060_Herythrocyte count QTL GWAS760060 (human)4e-13erythrocyte countred blood cell count (CMO:0000025)3101417558101417559Human
407356587GWAS1005563_Hbody height QTL GWAS1005563 (human)3e-09body height (VT:0001253)body height (CMO:0000106)3101365760101365761Human
407413284GWAS1062260_Hdiastolic blood pressure QTL GWAS1062260 (human)1e-13diastolic blood pressurediastolic blood pressure (CMO:0000005)3101492643101492644Human
407038384GWAS687360_Hred blood cell density measurement QTL GWAS687360 (human)1e-15red blood cell density measurement3101417558101417559Human
406916403GWAS565379_Hdiastolic blood pressure QTL GWAS565379 (human)9e-13diastolic blood pressurediastolic blood pressure (CMO:0000005)3101509521101509522Human
407154224GWAS803200_Halkaline phosphatase measurement QTL GWAS803200 (human)2e-10alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)3101365760101365761Human
407166386GWAS815362_Hserum alanine aminotransferase measurement QTL GWAS815362 (human)0.000009serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)3101417558101417559Human
407055162GWAS704138_Htelomere length QTL GWAS704138 (human)0.0000005telomere length3101349776101349777Human
407327674GWAS976650_Halpha fetoprotein measurement QTL GWAS976650 (human)5e-66blood alpha-fetoprotein amount (VT:0010776)3101417558101417559Human
406987516GWAS636492_Hmean corpuscular volume QTL GWAS636492 (human)2e-20mean corpuscular volumemean corpuscular volume (CMO:0000038)3101496512101496513Human

Markers in Region
SHGC-80773  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373101,067,291 - 101,067,592UniSTSGRCh37
Build 363102,549,981 - 102,550,282RGDNCBI36
Celera399,458,901 - 99,459,202RGD
Cytogenetic Map3q12UniSTS
HuRef398,435,877 - 98,436,178UniSTS
TNG Radiation Hybrid Map358423.0UniSTS
SHGC-84875  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373101,051,757 - 101,052,030UniSTSGRCh37
Build 363102,534,447 - 102,534,720RGDNCBI36
Celera399,443,370 - 99,443,643RGD
Cytogenetic Map3q12UniSTS
HuRef398,420,346 - 98,420,619UniSTS
TNG Radiation Hybrid Map358420.0UniSTS
SHGC-77165  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373101,052,515 - 101,052,616UniSTSGRCh37
Build 363102,535,205 - 102,535,306RGDNCBI36
Celera399,444,128 - 99,444,229RGD
Cytogenetic Map3q12UniSTS
HuRef398,421,104 - 98,421,205UniSTS
TNG Radiation Hybrid Map358431.0UniSTS
GeneMap99-GB4 RH Map3357.89UniSTS
A009P48  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373101,043,159 - 101,043,294UniSTSGRCh37
Build 363102,525,849 - 102,525,984RGDNCBI36
Celera399,434,761 - 99,434,896RGD
Cytogenetic Map3q12UniSTS
HuRef398,411,737 - 98,411,872UniSTS
GeneMap99-GB4 RH Map3349.45UniSTS
D3S3056  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373101,051,682 - 101,051,782UniSTSGRCh37
Build 363102,534,372 - 102,534,472RGDNCBI36
Celera399,443,295 - 99,443,395RGD
Cytogenetic Map3q12UniSTS
HuRef398,420,271 - 98,420,371UniSTS
Whitehead-YAC Contig Map3 UniSTS
G32758  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh373101,043,159 - 101,043,294UniSTSGRCh37
Celera399,434,761 - 99,434,896UniSTS
Cytogenetic Map3q12UniSTS
HuRef398,411,737 - 98,411,872UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2438 2788 2253 4973 1726 2351 6 623 1951 465 2269 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001077203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001282804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_020654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005247662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011513038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011513039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011513040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011513041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011513042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011513045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017006924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017006925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017006926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017006927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017006928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017006929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047448628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054347367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001740218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_007095714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008486767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA651903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB051494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC068764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC073861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC110994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF199458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF217504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI858732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL136599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC129988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU619557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX537943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH768344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000314261   ⟹   ENSP00000313624
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,324,273 - 101,513,241 (-)Ensembl
Ensembl Acc Id: ENST00000348610   ⟹   ENSP00000342159
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,325,867 - 101,513,223 (-)Ensembl
Ensembl Acc Id: ENST00000366089   ⟹   ENSP00000402977
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,347,326 - 101,347,913 (-)Ensembl
Ensembl Acc Id: ENST00000394085   ⟹   ENSP00000377647
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,325,540 - 101,333,269 (-)Ensembl
Ensembl Acc Id: ENST00000394091   ⟹   ENSP00000377651
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,324,273 - 101,513,184 (-)Ensembl
Ensembl Acc Id: ENST00000394094   ⟹   ENSP00000377654
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,324,273 - 101,513,205 (-)Ensembl
Ensembl Acc Id: ENST00000394095   ⟹   ENSP00000377655
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,324,205 - 101,513,212 (-)Ensembl
Ensembl Acc Id: ENST00000460107
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl3101,337,129 - 101,340,425 (-)Ensembl
RefSeq Acc Id: NM_001077203   ⟹   NP_001070671
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
GRCh373101,043,049 - 101,232,085 (-)NCBI
Build 363102,525,807 - 102,714,775 (-)NCBI Archive
Celera399,434,719 - 99,624,210 (-)RGD
HuRef398,411,611 - 98,600,626 (-)NCBI
CHM1_13101,005,992 - 101,195,158 (-)NCBI
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001282801   ⟹   NP_001269730
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
HuRef398,411,611 - 98,600,626 (-)NCBI
CHM1_13101,005,992 - 101,195,158 (-)NCBI
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001282802   ⟹   NP_001269731
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
HuRef398,411,611 - 98,600,626 (-)NCBI
CHM1_13101,005,992 - 101,195,158 (-)NCBI
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001282803   ⟹   NP_001269732
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
HuRef398,411,611 - 98,600,626 (-)NCBI
CHM1_13101,005,992 - 101,195,158 (-)NCBI
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001282804   ⟹   NP_001269733
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,371,854 - 101,513,212 (-)NCBI
HuRef398,411,611 - 98,600,626 (-)NCBI
CHM1_13101,053,723 - 101,195,158 (-)NCBI
T2T-CHM13v2.03104,077,729 - 104,219,481 (-)NCBI
Sequence:
RefSeq Acc Id: NM_020654   ⟹   NP_065705
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
GRCh373101,043,049 - 101,232,085 (-)NCBI
Build 363102,525,807 - 102,714,775 (-)NCBI Archive
Celera399,434,719 - 99,624,210 (-)RGD
HuRef398,411,611 - 98,600,626 (-)NCBI
CHM1_13101,005,992 - 101,195,158 (-)NCBI
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005247662   ⟹   XP_005247719
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
GRCh373101,043,049 - 101,232,085 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011513038   ⟹   XP_011511340
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011513040   ⟹   XP_011511342
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011513041   ⟹   XP_011511343
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011513042   ⟹   XP_011511344
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011513045   ⟹   XP_011511347
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,349,664 - 101,513,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017006926   ⟹   XP_016862415
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017006928   ⟹   XP_016862417
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,333,533 - 101,513,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047448627   ⟹   XP_047304583
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,324,205 - 101,513,212 (-)NCBI
RefSeq Acc Id: XM_047448628   ⟹   XP_047304584
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,332,799 - 101,513,212 (-)NCBI
RefSeq Acc Id: XM_054347358   ⟹   XP_054203333
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347359   ⟹   XP_054203334
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347360   ⟹   XP_054203335
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347361   ⟹   XP_054203336
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347362   ⟹   XP_054203337
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347363   ⟹   XP_054203338
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347364   ⟹   XP_054203339
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,039,411 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347365   ⟹   XP_054203340
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,038,677 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347366   ⟹   XP_054203341
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,030,073 - 104,219,481 (-)NCBI
RefSeq Acc Id: XM_054347367   ⟹   XP_054203342
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,055,542 - 104,219,481 (-)NCBI
RefSeq Acc Id: XR_007095713
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,340,109 - 101,513,212 (-)NCBI
RefSeq Acc Id: XR_007095714
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,340,109 - 101,513,212 (-)NCBI
RefSeq Acc Id: XR_008486766
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,045,987 - 104,219,481 (-)NCBI
RefSeq Acc Id: XR_008486767
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.03104,045,987 - 104,219,481 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001070671 (Get FASTA)   NCBI Sequence Viewer  
  NP_001269730 (Get FASTA)   NCBI Sequence Viewer  
  NP_001269731 (Get FASTA)   NCBI Sequence Viewer  
  NP_001269732 (Get FASTA)   NCBI Sequence Viewer  
  NP_001269733 (Get FASTA)   NCBI Sequence Viewer  
  NP_065705 (Get FASTA)   NCBI Sequence Viewer  
  XP_005247719 (Get FASTA)   NCBI Sequence Viewer  
  XP_011511340 (Get FASTA)   NCBI Sequence Viewer  
  XP_011511342 (Get FASTA)   NCBI Sequence Viewer  
  XP_011511343 (Get FASTA)   NCBI Sequence Viewer  
  XP_011511344 (Get FASTA)   NCBI Sequence Viewer  
  XP_011511347 (Get FASTA)   NCBI Sequence Viewer  
  XP_016862415 (Get FASTA)   NCBI Sequence Viewer  
  XP_016862417 (Get FASTA)   NCBI Sequence Viewer  
  XP_047304583 (Get FASTA)   NCBI Sequence Viewer  
  XP_047304584 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203333 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203334 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203335 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203336 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203337 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203338 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203339 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203340 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203341 (Get FASTA)   NCBI Sequence Viewer  
  XP_054203342 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG09703 (Get FASTA)   NCBI Sequence Viewer  
  AAI29989 (Get FASTA)   NCBI Sequence Viewer  
  AAL25651 (Get FASTA)   NCBI Sequence Viewer  
  BAB21798 (Get FASTA)   NCBI Sequence Viewer  
  BAG59804 (Get FASTA)   NCBI Sequence Viewer  
  CAB66534 (Get FASTA)   NCBI Sequence Viewer  
  CAD97911 (Get FASTA)   NCBI Sequence Viewer  
  CBX84919 (Get FASTA)   NCBI Sequence Viewer  
  EAW79796 (Get FASTA)   NCBI Sequence Viewer  
  EAW79797 (Get FASTA)   NCBI Sequence Viewer  
  EAW79798 (Get FASTA)   NCBI Sequence Viewer  
  EAW79799 (Get FASTA)   NCBI Sequence Viewer  
  EAW79800 (Get FASTA)   NCBI Sequence Viewer  
  EAW79801 (Get FASTA)   NCBI Sequence Viewer  
  EAW79802 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000313624
  ENSP00000313624.7
  ENSP00000342159
  ENSP00000342159.3
  ENSP00000377647.3
  ENSP00000377651
  ENSP00000377651.1
  ENSP00000377654
  ENSP00000377654.2
  ENSP00000377655
  ENSP00000377655.2
  ENSP00000402977.1
GenBank Protein Q9BQF6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001070671   ⟸   NM_001077203
- Peptide Label: isoform 2
- UniProtKB: J3QT09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_065705   ⟸   NM_020654
- Peptide Label: isoform 1
- UniProtKB: Q9C0F6 (UniProtKB/Swiss-Prot),   Q96PS5 (UniProtKB/Swiss-Prot),   Q7Z3F4 (UniProtKB/Swiss-Prot),   B7WNW8 (UniProtKB/Swiss-Prot),   A8MW39 (UniProtKB/Swiss-Prot),   A1L3A5 (UniProtKB/Swiss-Prot),   Q9HBT5 (UniProtKB/Swiss-Prot),   Q9BQF6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005247719   ⟸   XM_005247662
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: NP_001269732   ⟸   NM_001282803
- Peptide Label: isoform 5
- UniProtKB: Q9BQF6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001269731   ⟸   NM_001282802
- Peptide Label: isoform 4
- UniProtKB: Q9BQF6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001269730   ⟸   NM_001282801
- Peptide Label: isoform 3
- UniProtKB: Q9BQF6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001269733   ⟸   NM_001282804
- Peptide Label: isoform 6
- UniProtKB: Q9BQF6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011511344   ⟸   XM_011513042
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011511343   ⟸   XM_011513041
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011511342   ⟸   XM_011513040
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011511340   ⟸   XM_011513038
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011511347   ⟸   XM_011513045
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_016862415   ⟸   XM_017006926
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_016862417   ⟸   XM_017006928
- Peptide Label: isoform X7
- UniProtKB: B4DM92 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000342159   ⟸   ENST00000348610
Ensembl Acc Id: ENSP00000402977   ⟸   ENST00000366089
Ensembl Acc Id: ENSP00000313624   ⟸   ENST00000314261
Ensembl Acc Id: ENSP00000377647   ⟸   ENST00000394085
Ensembl Acc Id: ENSP00000377655   ⟸   ENST00000394095
Ensembl Acc Id: ENSP00000377654   ⟸   ENST00000394094
Ensembl Acc Id: ENSP00000377651   ⟸   ENST00000394091
RefSeq Acc Id: XP_047304583   ⟸   XM_047448627
- Peptide Label: isoform X6
RefSeq Acc Id: XP_047304584   ⟸   XM_047448628
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054203341   ⟸   XM_054347366
- Peptide Label: isoform X8
RefSeq Acc Id: XP_054203338   ⟸   XM_054347363
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054203337   ⟸   XM_054347362
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054203336   ⟸   XM_054347361
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054203335   ⟸   XM_054347360
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054203334   ⟸   XM_054347359
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054203333   ⟸   XM_054347358
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054203340   ⟸   XM_054347365
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054203339   ⟸   XM_054347364
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054203342   ⟸   XM_054347367
- Peptide Label: isoform X9
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9BQF6-F1-model_v2 AlphaFold Q9BQF6 1-1050 view protein structure

Promoters
RGD ID:6865142
Promoter ID:EPDNEW_H5736
Type:initiation region
Name:SENP7_1
Description:SUMO1/sentrin specific peptidase 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh383101,513,212 - 101,513,272EPDNEW
RGD ID:6800929
Promoter ID:HG_KWN:45710
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000358203,   ENST00000394094,   OTTHUMT00000313957,   OTTHUMT00000313960,   UC003DUV.1,   UC003DUX.1
Position:
Human AssemblyChrPosition (strand)Source
Build 363102,714,311 - 102,714,962 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30402 AgrOrtholog
COSMIC SENP7 COSMIC
Ensembl Genes ENSG00000138468 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000314261 ENTREZGENE
  ENST00000314261.11 UniProtKB/Swiss-Prot
  ENST00000348610 ENTREZGENE
  ENST00000348610.3 UniProtKB/Swiss-Prot
  ENST00000366089.2 UniProtKB/TrEMBL
  ENST00000394085.7 UniProtKB/Swiss-Prot
  ENST00000394091 ENTREZGENE
  ENST00000394091.5 UniProtKB/Swiss-Prot
  ENST00000394094 ENTREZGENE
  ENST00000394094.6 UniProtKB/TrEMBL
  ENST00000394095 ENTREZGENE
  ENST00000394095.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.418.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000138468 GTEx
HGNC ID HGNC:30402 ENTREZGENE
Human Proteome Map SENP7 Human Proteome Map
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C48_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sentrin-specific_protease UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:57337 UniProtKB/Swiss-Prot
NCBI Gene 57337 ENTREZGENE
OMIM 612846 OMIM
PANTHER SENTRIN-SPECIFIC PROTEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SENTRIN-SPECIFIC PROTEASE 7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_C48 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134925171 PharmGKB
PROSITE ULP_PROTEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A1L3A5 ENTREZGENE
  A8MW39 ENTREZGENE
  B4DM92 ENTREZGENE, UniProtKB/TrEMBL
  B7WNW8 ENTREZGENE
  H7C1X8_HUMAN UniProtKB/TrEMBL
  J3QT09 ENTREZGENE, UniProtKB/TrEMBL
  Q7Z3F4 ENTREZGENE
  Q96PS5 ENTREZGENE
  Q9BQF6 ENTREZGENE
  Q9C0F6 ENTREZGENE
  Q9HBT5 ENTREZGENE
  SENP7_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A1L3A5 UniProtKB/Swiss-Prot
  A8MW39 UniProtKB/Swiss-Prot
  B7WNW8 UniProtKB/Swiss-Prot
  Q7Z3F4 UniProtKB/Swiss-Prot
  Q96PS5 UniProtKB/Swiss-Prot
  Q9C0F6 UniProtKB/Swiss-Prot
  Q9HBT5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-27 SENP7  SUMO specific peptidase 7  SENP7  SUMO1/sentrin specific peptidase 7  Symbol and/or name change 5135510 APPROVED