Rasip1 (Ras interacting protein 1) - Rat Genome Database

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Gene: Rasip1 (Ras interacting protein 1) Mus musculus
Analyze
Symbol: Rasip1
Name: Ras interacting protein 1
RGD ID: 1313234
MGI Page MGI
Description: Predicted to enable protein homodimerization activity and small GTPase binding activity. Involved in angiogenesis; branching morphogenesis of an epithelial tube; and vasculogenesis. Predicted to be located in Golgi apparatus and perinuclear region of cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cell-cell junction. Is expressed in several structures, including body cavity or lining; cardiovascular system; extraembryonic component; genitourinary system; and vertebral axis musculature. Orthologous to human RASIP1 (Ras interacting protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110025D03Rik; 2610025P08Rik; AI853551; MGC150078; Rain; ras-interacting protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,276,961 - 45,288,516 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,276,912 - 45,288,517 (+)EnsemblGRCm39 Ensembl
GRCm38745,627,537 - 45,639,092 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,627,488 - 45,639,093 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,882,907 - 52,894,462 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,495,579 - 45,507,134 (+)NCBIMGSCv36mm8
Celera741,089,079 - 41,100,635 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12644598   PMID:14610273   PMID:15031288   PMID:15489334   PMID:16141072   PMID:16141073   PMID:19272373  
PMID:21267068   PMID:21396893   PMID:21677750   PMID:21873635   PMID:22076636   PMID:23886837   PMID:24622510   PMID:26002917   PMID:26897025   PMID:27486147   PMID:27789228   PMID:29669786  
PMID:30042182   PMID:31112136  


Genomics

Comparative Map Data
Rasip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,276,961 - 45,288,516 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,276,912 - 45,288,517 (+)EnsemblGRCm39 Ensembl
GRCm38745,627,537 - 45,639,092 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,627,488 - 45,639,093 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,882,907 - 52,894,462 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,495,579 - 45,507,134 (+)NCBIMGSCv36mm8
Celera741,089,079 - 41,100,635 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.39NCBI
RASIP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,720,585 - 48,740,610 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,720,585 - 48,740,610 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,223,842 - 49,243,867 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361953,915,654 - 53,935,782 (-)NCBINCBI36Build 36hg18NCBI36
Build 341953,915,653 - 53,935,782NCBI
Celera1946,089,934 - 46,110,062 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,603,007 - 45,622,781 (-)NCBIHuRef
CHM1_11949,225,580 - 49,245,732 (-)NCBICHM1_1
T2T-CHM13v2.01951,715,002 - 51,735,029 (-)NCBIT2T-CHM13v2.0
Rasip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,233,599 - 105,246,028 (+)NCBIGRCr8
mRatBN7.2196,097,135 - 96,109,564 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,091,074 - 96,109,562 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,482,573 - 101,495,002 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,955,274 - 109,967,703 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,245,644 - 103,258,074 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,609,209 - 101,621,648 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,610,773 - 101,621,646 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,687,843 - 102,700,428 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,097,668 - 96,108,543 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,174,114 - 96,186,654 (+)NCBI
Celera190,352,345 - 90,363,220 (+)NCBICelera
Cytogenetic Map1q22NCBI
Rasip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,831,123 - 1,843,905 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,830,574 - 1,844,107 (+)NCBIChiLan1.0ChiLan1.0
RASIP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,823,848 - 54,843,803 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,750,190 - 56,770,147 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,720,179 - 45,740,131 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,311,649 - 54,318,585 (-)NCBIpanpan1.1PanPan1.1panPan2
RASIP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,583,169 - 107,597,683 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,581,424 - 107,597,682 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,105,550 - 107,119,765 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,107,785 - 108,121,968 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,107,111 - 108,121,992 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,774,623 - 107,788,818 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,421,540 - 107,435,931 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,257,120 - 108,271,542 (+)NCBIUU_Cfam_GSD_1.0
Rasip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,125,378 - 21,137,442 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,743,564 - 2,754,395 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,743,568 - 2,754,618 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASIP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,058,759 - 54,072,459 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,058,748 - 54,072,415 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,806,097 - 49,819,876 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RASIP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1641,970,704 - 41,997,951 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl641,991,176 - 41,996,155 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607321,840,051 - 21,860,422 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rasip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,177,092 - 5,189,471 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,176,697 - 5,189,673 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:262
Count of miRNA genes:218
Interacting mature miRNAs:239
Transcripts:ENSMUST00000057927
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse

Markers in Region
AI853551  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38745,638,874 - 45,638,970UniSTSGRCm38
MGSCv37752,894,244 - 52,894,340UniSTSGRCm37
Celera741,100,417 - 41,100,513UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map7B2UniSTS
Whitehead/MRC_RH7566.14UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000057927   ⟹   ENSMUSP00000062429
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,276,912 - 45,288,517 (+)Ensembl
GRCm38.p6 Ensembl745,627,488 - 45,639,093 (+)Ensembl
RefSeq Acc Id: NM_028544   ⟹   NP_082820
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,276,961 - 45,288,516 (+)NCBI
GRCm38745,627,537 - 45,639,092 (+)NCBI
MGSCv37752,882,907 - 52,894,462 (+)RGD
Celera741,089,079 - 41,100,635 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_082820   ⟸   NM_028544
- UniProtKB: E9QLI7 (UniProtKB/Swiss-Prot),   Q6GQW4 (UniProtKB/Swiss-Prot),   Q3U0S6 (UniProtKB/Swiss-Prot),   B9EK92 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000062429   ⟸   ENSMUST00000057927
Protein Domains
Dilute   Ras-associating

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3U0S6-F1-model_v2 AlphaFold Q3U0S6 1-961 view protein structure

Promoters
RGD ID:8664059
Promoter ID:EPDNEW_M10061
Type:initiation region
Name:Rasip1_1
Description:Mus musculus Ras interacting protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38745,627,516 - 45,627,576EPDNEW
RGD ID:6841905
Promoter ID:MM_KWN:50436
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Lung
Transcripts:OTTMUST00000073119,   OTTMUST00000073120
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36752,882,736 - 52,883,236 (+)MPROMDB
RGD ID:6849236
Promoter ID:MM_XEF:6552
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   Spleen
Transcripts:NM_001106261
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36752,884,016 - 52,884,516 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917153 AgrOrtholog
Ensembl Genes ENSMUSG00000044562 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000057927 ENTREZGENE
  ENSMUST00000057927.10 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.200.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CBD_Rasip1/Radil UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dilute_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Vascular_dev_regulator UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69903 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1917153 ENTREZGENE
NCBI Gene 69903 ENTREZGENE
PANTHER DILUTE DOMAIN-CONTAINING PROTEIN YPR089W UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS-INTERACTING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DIL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00788 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rasip1 PhenoGen
PROSITE DILUTE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DIL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00314 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49879 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0JNY4_MOUSE UniProtKB/TrEMBL
  B9EK92 ENTREZGENE, UniProtKB/TrEMBL
  E9QLI7 ENTREZGENE
  Q3U0S6 ENTREZGENE
  Q6GQW4 ENTREZGENE
  Q8CCF1_MOUSE UniProtKB/TrEMBL
  Q8R2L4_MOUSE UniProtKB/TrEMBL
  Q9D0D0_MOUSE UniProtKB/TrEMBL
  RAIN_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary E9QLI7 UniProtKB/Swiss-Prot
  Q6GQW4 UniProtKB/Swiss-Prot