Fbxo16 (F-box protein 16) - Rat Genome Database

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Gene: Fbxo16 (F-box protein 16) Mus musculus
Analyze
Symbol: Fbxo16
Name: F-box protein 16
RGD ID: 1312848
MGI Page MGI
Description: Orthologous to human FBXO16 (F-box protein 16).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4932435C24Rik; F-box only protein 16; Fbx16; MGC144594
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391465,504,067 - 65,561,422 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1465,504,067 - 65,561,422 (+)EnsemblGRCm39 Ensembl
GRCm381465,266,618 - 65,323,973 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1465,266,618 - 65,323,973 (+)EnsemblGRCm38mm10GRCm38
MGSCv371465,885,538 - 65,940,339 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361464,220,811 - 64,275,612 (+)NCBIMGSCv36mm8
Celera1463,023,781 - 63,072,756 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Systematic analysis and nomenclature of mammalian F-box proteins. Jin J, etal., Genes Dev 2004 Nov 1;18(21):2573-80.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
8. A family of mammalian F-box proteins. Winston JT, etal., Curr Biol 1999 Oct 21;9(20):1180-2.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21267068   PMID:27626380   PMID:38355793  


Genomics

Comparative Map Data
Fbxo16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391465,504,067 - 65,561,422 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1465,504,067 - 65,561,422 (+)EnsemblGRCm39 Ensembl
GRCm381465,266,618 - 65,323,973 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1465,266,618 - 65,323,973 (+)EnsemblGRCm38mm10GRCm38
MGSCv371465,885,538 - 65,940,339 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361464,220,811 - 64,275,612 (+)NCBIMGSCv36mm8
Celera1463,023,781 - 63,072,756 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.19NCBI
FBXO16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38828,428,412 - 28,490,229 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl828,348,287 - 28,490,278 (-)EnsemblGRCh38hg38GRCh38
GRCh37828,285,929 - 28,347,746 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36828,341,848 - 28,403,703 (-)NCBINCBI36Build 36hg18NCBI36
Build 34828,341,847 - 28,403,703NCBI
Celera827,245,788 - 27,307,641 (-)NCBICelera
Cytogenetic Map8p21.1NCBI
HuRef826,830,955 - 26,893,082 (-)NCBIHuRef
CHM1_1828,487,808 - 28,549,727 (-)NCBICHM1_1
T2T-CHM13v2.0828,706,607 - 28,768,389 (-)NCBIT2T-CHM13v2.0
Fbxo16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81543,667,207 - 43,717,096 (+)NCBIGRCr8
mRatBN7.21539,492,268 - 39,541,493 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1539,492,377 - 39,541,480 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1541,356,452 - 41,405,579 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01542,507,157 - 42,555,767 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01540,952,835 - 41,001,853 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01548,673,172 - 48,723,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1548,674,380 - 48,723,353 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01552,415,297 - 52,465,140 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41544,690,042 - 44,736,309 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11544,705,741 - 44,752,008 (+)NCBI
Celera1539,167,277 - 39,216,208 (+)NCBICelera
Cytogenetic Map15p12NCBI
Fbxo16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540350,835,121 - 50,887,532 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540350,835,073 - 50,887,523 (-)NCBIChiLan1.0ChiLan1.0
FBXO16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2746,959,086 - 47,032,063 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1822,674,586 - 22,744,934 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0827,708,114 - 27,770,216 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1824,907,899 - 24,969,748 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl824,907,899 - 24,969,748 (-)Ensemblpanpan1.1panPan2
FBXO16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12529,079,171 - 29,137,548 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2529,729,146 - 29,791,631 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02529,237,709 - 29,300,022 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2529,237,746 - 29,294,156 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12529,198,057 - 29,260,352 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02529,082,127 - 29,144,494 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02529,247,803 - 29,306,268 (+)NCBIUU_Cfam_GSD_1.0
Fbxo16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049437,323,891 - 7,379,939 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366751,208,566 - 1,262,409 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366751,208,170 - 1,262,131 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF395
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1412,220,506 - 12,277,107 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11412,218,979 - 12,277,165 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21413,378,644 - 13,431,944 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXO16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1826,533,699 - 26,595,603 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl826,529,669 - 26,594,623 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605215,541,907 - 15,603,340 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxo16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475823,100,932 - 23,143,984 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475823,090,074 - 23,143,907 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fbxo16
1760 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:70
Count of miRNA genes:67
Interacting mature miRNAs:70
Transcripts:ENSMUST00000169656
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145608238190082509Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145654674590546941Mouse
1357565wrmod1_mwobbler modifier 1 (mouse)Not determined1458179640101859473Mouse
1300666Fembm2_mfemoral bone morphometry 2 (mouse)Not determined146239746096397680Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4033731974337319Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144945542583455556Mouse
11039527Ccc2_mcolitis susceptibility in the Collaborative Cross 2 (mouse)145991861294138217Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144306584777066045Mouse
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145393744087937440Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143743018571430320Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144303727077037418Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000169656   ⟹   ENSMUSP00000130805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1465,504,181 - 65,540,741 (+)Ensembl
GRCm38.p6 Ensembl1465,266,732 - 65,303,292 (+)Ensembl
Ensembl Acc Id: ENSMUST00000223608
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1465,504,104 - 65,558,950 (+)Ensembl
GRCm38.p6 Ensembl1465,266,655 - 65,321,501 (+)Ensembl
Ensembl Acc Id: ENSMUST00000224629   ⟹   ENSMUSP00000153015
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1465,504,067 - 65,561,420 (+)Ensembl
GRCm38.p6 Ensembl1465,266,618 - 65,323,971 (+)Ensembl
Ensembl Acc Id: ENSMUST00000226005   ⟹   ENSMUSP00000153094
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1465,504,186 - 65,561,422 (+)Ensembl
GRCm38.p6 Ensembl1465,266,737 - 65,323,973 (+)Ensembl
RefSeq Acc Id: NM_001360381   ⟹   NP_001347310
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391465,504,067 - 65,561,422 (+)NCBI
GRCm381465,266,618 - 65,323,973 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001360383   ⟹   NP_001347312
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391465,504,067 - 65,561,422 (+)NCBI
GRCm381465,266,618 - 65,323,973 (+)NCBI
Sequence:
RefSeq Acc Id: NM_015795   ⟹   NP_056610
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391465,504,067 - 65,561,422 (+)NCBI
GRCm381465,266,618 - 65,323,973 (+)NCBI
MGSCv371465,885,538 - 65,940,339 (+)RGD
Celera1463,023,781 - 63,072,756 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_056610   ⟸   NM_015795
- Peptide Label: isoform 1
- UniProtKB: Q3TP74 (UniProtKB/Swiss-Prot),   Q8C5V6 (UniProtKB/Swiss-Prot),   Q9QZM9 (UniProtKB/Swiss-Prot),   Q14BG9 (UniProtKB/TrEMBL),   Q8BRT0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001347312   ⟸   NM_001360383
- Peptide Label: isoform 3
- UniProtKB: Q0VGS0 (UniProtKB/TrEMBL),   Q8BRT0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001347310   ⟸   NM_001360381
- Peptide Label: isoform 2
- UniProtKB: Q8BRT0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000153015   ⟸   ENSMUST00000224629
Ensembl Acc Id: ENSMUSP00000153094   ⟸   ENSMUST00000226005
Ensembl Acc Id: ENSMUSP00000130805   ⟸   ENSMUST00000169656
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZM9-F1-model_v2 AlphaFold Q9QZM9 1-334 view protein structure

Promoters
RGD ID:8682758
Promoter ID:EPDNEW_M19410
Type:initiation region
Name:Fbxo16_1
Description:Mus musculus F-box protein 16 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381465,266,727 - 65,266,787EPDNEW
RGD ID:6824927
Promoter ID:MM_KWN:17242
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney
Transcripts:ENSMUST00000043554,   UC007UJC.1,   UC007UJE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361465,885,149 - 65,885,649 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1354706 AgrOrtholog
Ensembl Genes ENSMUSG00000034532 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000169656.3 UniProtKB/TrEMBL
  ENSMUST00000224629 ENTREZGENE
  ENSMUST00000224629.2 UniProtKB/Swiss-Prot
  ENSMUST00000226005 ENTREZGENE
  ENSMUST00000226005.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GEF_Ubiquitin-Prot_Reg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:50759 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1354706 ENTREZGENE
NCBI Gene 50759 ENTREZGENE
PANTHER EPITHELIAL CELL-TRANSFORMING SEQUENCE 2 ONCOGENE-LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  F-BOX ONLY PROTEIN 16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fbxo16 PhenoGen
PROSITE FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt FBX16_MOUSE UniProtKB/Swiss-Prot
  Q0VGS0 ENTREZGENE, UniProtKB/TrEMBL
  Q14BG9 ENTREZGENE, UniProtKB/TrEMBL
  Q3TP74 ENTREZGENE
  Q8BRT0 ENTREZGENE, UniProtKB/TrEMBL
  Q8C5V6 ENTREZGENE
  Q9QZM9 ENTREZGENE
UniProt Secondary Q3TP74 UniProtKB/Swiss-Prot
  Q8C5V6 UniProtKB/Swiss-Prot