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Gene: FBXO16 (F-box protein 16) Homo sapiens
Symbol: FBXO16
Name: F-box protein 16
Description: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: F-box only protein 16; FBX16; MGC125923; MGC125924; MGC125925
Mus musculus (house mouse) : Fbxo16 (F-box protein 16)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxo16 (F-box protein 16)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo16 (F-box protein 16)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO16 (F-box protein 16)
Canis lupus familiaris (dog) : FBXO16 (F-box protein 16)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo16 (F-box protein 16)
Sus scrofa (pig) : FBXO16 (F-box protein 16)
Chlorocebus sabaeus (green monkey) : FBXO16 (F-box protein 16)
Heterocephalus glaber (naked mole-rat) : Fbxo16 (F-box protein 16)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl828,348,287 - 28,490,278 (-)Ensembl
GRCh38828,428,408 - 28,490,318 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37828,285,925 - 28,347,835 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36828,341,848 - 28,403,703 (-)NCBINCBI36hg18NCBI36
Build 34828,341,847 - 28,403,703NCBI
Celera827,245,788 - 27,307,641 (-)NCBI
Cytogenetic Map8p21.1NCBI
HuRef826,830,955 - 26,893,082 (-)NCBIHuRef
CHM1_1828,487,808 - 28,549,727 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FBXO16
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312847
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.