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Gene: Thoc5 (THO complex 5) Mus musculus
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Symbol: Thoc5
Name: THO complex 5
Description: Exhibits mRNA binding activity. Involved in several processes, including negative regulation of macrophage differentiation; primitive hemopoiesis; and regulation of mRNA export from nucleus. Localizes to the nucleus. Predicted to colocalize with the nuclear chromosome, telomeric region. Human ortholog(s) of this gene implicated in breast carcinoma. Is expressed in early conceptus and inner cell mass. Orthologous to human THOC5 (THO complex 5); PARTICIPATES IN NXF1-NXT1 export pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; lead diacetate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1700060C24Rik; A430085L24Rik; Fmip; Fms interacting protein; fms-interacting protein; MGC49541; PK1.3; RP23-64E17.4; serum/glucocorticoid regulated kinase 2; Sgk2; THO complex subunit 5 homolog
Orthologs:
Homo sapiens (human) : THOC5 (THO complex 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Thoc5 (THO complex 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thoc5 (THO complex 5)
Pan paniscus (bonobo/pygmy chimpanzee) : THOC5 (THO complex 5)
Canis lupus familiaris (dog) : THOC5 (THO complex 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thoc5 (THO complex 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl114,895,320 - 4,928,867 (+)Ensembl
GRCm38114,895,283 - 4,928,867 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37114,795,346 - 4,828,868 (+)NCBIGRCm37mm9NCBIm37
MGSCv36114,795,346 - 4,828,868 (+)NCBImm8
Celera115,392,170 - 5,426,353 (+)NCBICelera
Cytogenetic Map11 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Thoc5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312750
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.