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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of GOLT1B mRNA] | CTD | PMID:31150632 | (S)-nicotine | multiple interactions | ISO | RGD:1552821 | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1,2-dichloroethane | decreases expression | ISO | RGD:1552821 | 6480464 | ethylene dichloride results in decreased expression of GOLT1B mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1552821 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of GOLT1B mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1552821 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of GOLT1B mRNA | CTD | PMID:22206623 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | increases expression | ISO | RGD:1552821 | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | RGD:1552821 | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | RGD:1552821 | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | RGD:1349948 | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1552821 | 6480464 | Tetrachlorodibenzodioxin affects the expression of GOLT1B mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1552821 | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of GOLT1B mRNA | CTD | PMID:25975270 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 4-dinitrotoluene affects the expression of GOLT1B mRNA | CTD | PMID:21346803 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | RGD:1349948 | 6480464 | tetrabromobisphenol A results in increased expression of GOLT1B protein | CTD | PMID:31675489 | 4-hydroxyphenyl retinamide | decreases expression | ISO | RGD:1552821 | 6480464 | Fenretinide results in decreased expression of GOLT1B mRNA | CTD | PMID:28973697 | acrolein | multiple interactions | ISO | RGD:1349948 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of GOLT1B mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of GOLT1B mRNA | CTD | PMID:32699268 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of GOLT1B mRNA | CTD | PMID:28959563 | aflatoxin B1 | decreases methylation | ISO | RGD:1349948 | 6480464 | Aflatoxin B1 results in decreased methylation of GOLT1B gene | CTD | PMID:27153756 | alpha-pinene | multiple interactions | ISO | RGD:1349948 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of GOLT1B mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of GOLT1B mRNA | CTD | PMID:32699268 | aristolochic acid A | decreases expression | ISO | RGD:1349948 | 6480464 | aristolochic acid I results in decreased expression of GOLT1B mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | RGD:1349948 | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to GOLT1B mRNA] | CTD | PMID:32406909 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GOLT1B mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:1349948 | 6480464 | bisphenol A results in decreased expression of GOLT1B protein | CTD | PMID:31675489 | bisphenol A | decreases methylation | ISO | RGD:1349948 | 6480464 | bisphenol A results in decreased methylation of GOLT1B gene | CTD | PMID:31601247 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of GOLT1B gene | CTD | PMID:28505145 | Bisphenol B | increases expression | ISO | RGD:1349948 | 6480464 | bisphenol B results in increased expression of GOLT1B protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | RGD:1349948 | 6480464 | bisphenol F results in increased expression of GOLT1B protein | CTD | PMID:34186270 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of GOLT1B mRNA | CTD | PMID:33453195 | caffeine | multiple interactions | ISO | RGD:1552821 | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | captan | decreases expression | ISO | RGD:1552821 | 6480464 | Captan results in decreased expression of GOLT1B mRNA | CTD | PMID:31558096 | carbon nanotube | increases expression | ISO | RGD:1552821 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | RGD:1349948 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GOLT1B gene] | CTD | PMID:28238834 | choline | multiple interactions | ISO | RGD:1552821 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of GOLT1B mRNA | CTD | PMID:20938992 | copper atom | multiple interactions | ISO | RGD:1349948 | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of GOLT1B mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | RGD:1349948 | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of GOLT1B mRNA | CTD | PMID:20971185 | copper(II) sulfate | increases expression | ISO | RGD:1349948 | 6480464 | Copper Sulfate results in increased expression of GOLT1B mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | ISO | RGD:1552821 | 6480464 | Asbestos, Crocidolite results in decreased expression of GOLT1B mRNA | CTD | PMID:29279043 | cyclosporin A | increases expression | ISO | RGD:1349948 | 6480464 | Cyclosporine results in increased expression of GOLT1B mRNA | CTD | PMID:20106945 more ... | decabromodiphenyl ether | increases expression | ISO | RGD:1349948 | 6480464 | decabromobiphenyl ether results in increased expression of GOLT1B protein | CTD | PMID:31675489 | dicrotophos | decreases expression | ISO | RGD:1349948 | 6480464 | dicrotophos results in decreased expression of GOLT1B mRNA | CTD | PMID:28302478 | folic acid | multiple interactions | ISO | RGD:1552821 | 6480464 | [1 more ... | CTD | PMID:20938992, PMID:22206623 | folic acid | decreases expression | ISO | RGD:1349948 | 6480464 | Folic Acid results in decreased expression of GOLT1B mRNA | CTD | PMID:21867686 | folic acid | decreases expression | ISO | RGD:1552821 | 6480464 | Folic Acid results in decreased expression of GOLT1B mRNA | CTD | PMID:25629700 | folpet | decreases expression | ISO | RGD:1552821 | 6480464 | folpet results in decreased expression of GOLT1B mRNA | CTD | PMID:31558096 | formaldehyde | increases expression | ISO | RGD:1349948 | 6480464 | Formaldehyde results in increased expression of GOLT1B mRNA | CTD | PMID:23649840 | ivermectin | decreases expression | ISO | RGD:1349948 | 6480464 | Ivermectin results in decreased expression of GOLT1B protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | RGD:1552821 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of GOLT1B mRNA | CTD | PMID:20938992 | lead(0) | increases expression | ISO | RGD:1349948 | 6480464 | Lead results in increased expression of GOLT1B mRNA | CTD | PMID:19921347 | lead(2+) | increases expression | ISO | RGD:1349948 | 6480464 | Lead results in increased expression of GOLT1B mRNA | CTD | PMID:19921347 | methyl methanesulfonate | increases expression | ISO | RGD:1349948 | 6480464 | Methyl Methanesulfonate results in increased expression of GOLT1B mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | RGD:1349948 | 6480464 | methylmercuric chloride results in increased expression of GOLT1B mRNA | CTD | PMID:28001369 | methylparaben | increases expression | ISO | RGD:1349948 | 6480464 | methylparaben results in increased expression of GOLT1B mRNA | CTD | PMID:31745603 | nickel atom | increases expression | ISO | RGD:1349948 | 6480464 | Nickel results in increased expression of GOLT1B mRNA | CTD | PMID:25583101 | nicotine | multiple interactions | ISO | RGD:1552821 | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | ozone | multiple interactions | ISO | RGD:1349948 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of GOLT1B mRNA more ... | CTD | PMID:32699268 | paracetamol | affects expression | ISO | RGD:1552821 | 6480464 | Acetaminophen affects the expression of GOLT1B mRNA | CTD | PMID:17562736 | picoxystrobin | increases expression | ISO | RGD:1349948 | 6480464 | picoxystrobin results in increased expression of GOLT1B mRNA | CTD | PMID:33512557 | pirinixic acid | multiple interactions | ISO | RGD:1552821 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of GOLT1B mRNA | CTD | PMID:19710929 | propiconazole | increases expression | ISO | RGD:1552821 | 6480464 | propiconazole results in increased expression of GOLT1B mRNA | CTD | PMID:21278054 | resveratrol | multiple interactions | ISO | RGD:1349948 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of GOLT1B mRNA | CTD | PMID:23557933 | silicon dioxide | increases expression | ISO | RGD:1552821 | 6480464 | Silicon Dioxide results in increased expression of GOLT1B mRNA | CTD | PMID:23221170 | sodium arsenate | decreases expression | ISO | RGD:1552821 | 6480464 | sodium arsenate results in decreased expression of GOLT1B mRNA | CTD | PMID:21795629 | sodium arsenate | increases expression | ISO | RGD:1552821 | 6480464 | sodium arsenate results in increased expression of GOLT1B mRNA | CTD | PMID:21795629 | sodium dichromate | decreases expression | ISO | RGD:1552821 | 6480464 | sodium bichromate results in decreased expression of GOLT1B mRNA | CTD | PMID:31558096 | testosterone | decreases expression | ISO | RGD:1552821 | 6480464 | Testosterone deficiency results in decreased expression of GOLT1B mRNA | CTD | PMID:33848595 | tetrachloroethene | decreases expression | ISO | RGD:1552821 | 6480464 | Tetrachloroethylene results in decreased expression of GOLT1B mRNA | CTD | PMID:28973375 | tetrachloromethane | increases expression | ISO | RGD:1552821 | 6480464 | Carbon Tetrachloride results in increased expression of GOLT1B mRNA | CTD | PMID:27339419, PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of GOLT1B mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of GOLT1B mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of GOLT1B mRNA | CTD | PMID:23411599 | trimellitic anhydride | increases expression | ISO | RGD:1552821 | 6480464 | trimellitic anhydride results in increased expression of GOLT1B mRNA | CTD | PMID:19042947 | triptonide | increases expression | ISO | RGD:1552821 | 6480464 | triptonide results in increased expression of GOLT1B mRNA | CTD | PMID:33045310 | troglitazone | increases expression | ISO | RGD:1552821 | 6480464 | troglitazone results in increased expression of GOLT1B mRNA | CTD | PMID:28973697 | valproic acid | decreases expression | ISO | RGD:1552821 | 6480464 | Valproic Acid results in decreased expression of GOLT1B mRNA | CTD | PMID:21427059 | valproic acid | affects expression | ISO | RGD:1552821 | 6480464 | Valproic Acid affects the expression of GOLT1B mRNA | CTD | PMID:17292431, PMID:17963808 | valproic acid | decreases expression | ISO | RGD:1349948 | 6480464 | Valproic Acid results in decreased expression of GOLT1B mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | RGD:1349948 | 6480464 | Valproic Acid affects the expression of GOLT1B mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | RGD:1349948 | 6480464 | Valproic Acid results in increased expression of GOLT1B mRNA | CTD | PMID:29501571 | |