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Gene: Psmd6 (proteasome 26S subunit, non-ATPase 6) Ictidomys tridecemlineatus

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Symbol:

Psmd6

Name:

proteasome 26S subunit, non-ATPase 6

RGD ID:

12732614

Description:

INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ASSOCIATED WITH human immunodeficiency virus infectious disease (ortholog); type 2 diabetes mellitus (ortholog); FOUND IN proteasome accessory complex (inferred); proteasome complex (inferred); proteasome regulatory particle (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

26S proteasome non-ATPase regulatory subunit 6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	164,013,905 - 164,024,218 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936637	2,403,450 - 2,416,917 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936637	2,403,456 - 2,413,772 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Psmd6	Squirrel	human immunodeficiency virus infectious disease		ISO	RGD:1351950	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:15308739
Psmd6	Squirrel	type 2 diabetes mellitus		ISO	RGD:1351950	9068941	CTD Direct Evidence: marker/mechanism	CTD	PMID:22158537

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Psmd6	Squirrel	proteasome-mediated ubiquitin-dependent protein catabolic process	involved_in	IEA	PANTHER:PTN000365359	150520179		TreeGrafter	GO_REF:0000118

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Psmd6	Squirrel	proteasome accessory complex	part_of	IEA	UniProtKB:Q99JI4\|ensembl:ENSMUSP00000022256	150520179		Ensembl	GO_REF:0000107
Psmd6	Squirrel	proteasome complex	part_of	IEA	UniProtKB:Q15008\|ensembl:ENSP00000295901	150520179		Ensembl	GO_REF:0000107
Psmd6	Squirrel	proteasome complex	part_of	IEA	ARBA:ARBA00029017	150520179		UniProt	GO_REF:0000117
Psmd6	Squirrel	proteasome complex	part_of	IEA	UniProtKB-KW:KW-0647	150520179		UniProt	GO_REF:0000043
Psmd6	Squirrel	proteasome regulatory particle	part_of	IEA	PANTHER:PTN000365359	150520179		TreeGrafter	GO_REF:0000118

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Psmd6	Squirrel	protein binding	enables	ISO	UniProtKB:P55036	9068941	PMID:16990800, PMID:33961781, PMID:35271311	IntAct	PMID:16990800\|PMID:33961781\|PMID:35271311
Psmd6	Squirrel	protein binding	enables	ISO	UniProtKB:Q9UMX0\|UniProtKB:Q9UMX0-2	9068941	PMID:25416956	IntAct	PMID:25416956
Psmd6	Squirrel	protein binding	enables	ISO	UniProtKB:Q96FZ5\|UniProtKB:Q9H8Y8	9068941	PMID:32296183	IntAct	PMID:32296183

PMID:22301074	PMID:30032202

Psmd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	164,013,905 - 164,024,218 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936637	2,403,450 - 2,416,917 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936637	2,403,456 - 2,413,772 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PSMD6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	64,010,551 - 64,024,007 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	64,010,550 - 64,024,010 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	63,996,227 - 64,009,683 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	63,971,271 - 63,984,160 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	64,013,003 - 64,025,892 (-)	NCBI		Celera
Cytogenetic Map	3	p14.1	NCBI
HuRef	3	64,093,293 - 64,106,754 (-)	NCBI		HuRef
CHM1_1	3	63,947,557 - 63,961,018 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	64,054,166 - 64,067,621 (-)	NCBI		T2T-CHM13v2.0

Psmd6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	8,348,818 - 8,357,578 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	8,348,779 - 8,357,589 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	14,112,185 - 14,120,945 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	14,112,174 - 14,120,984 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	14,944,699 - 14,953,418 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	12,905,452 - 12,914,171 (-)	NCBI		MGSCv36	mm8
Celera	14	9,775,803 - 9,784,442 (-)	NCBI		Celera
Cytogenetic Map	14	A1	NCBI
cM Map	14	7.08	NCBI

Psmd6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	13,532,675 - 13,542,682 (+)	NCBI		GRCr8
mRatBN7.2	15	11,102,174 - 11,112,180 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	11,102,180 - 11,205,620 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	13,228,776 - 13,238,756 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	14,180,928 - 14,190,933 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	12,442,072 - 12,452,052 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	12,407,557 - 12,416,153 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	12,407,524 - 12,416,105 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	16,438,829 - 16,447,425 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	12,650,570 - 12,660,487 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	12,650,569 - 12,660,487 (+)	NCBI
Celera	15	11,109,222 - 11,119,073 (+)	NCBI		Celera
Cytogenetic Map	15	p16	NCBI

Psmd6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955517	1,874,874 - 1,886,480 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955517	1,874,874 - 1,886,480 (+)	NCBI	ChiLan1.0	ChiLan1.0

PSMD6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	63,930,332 - 63,943,839 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	63,935,120 - 63,948,632 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	63,912,457 - 63,925,443 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	65,291,810 - 65,304,861 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	65,291,696 - 65,304,861 (-)	Ensembl	panpan1.1		panPan2

PSMD6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	27,206,801 - 27,220,059 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	27,131,114 - 27,144,455 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	27,443,760 - 27,457,109 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	27,443,744 - 27,457,071 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	26,940,538 - 26,953,881 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	27,290,971 - 27,304,299 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	27,353,933 - 27,408,837 (+)	NCBI		UU_Cfam_GSD_1.0

PSMD6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	45,496,362 - 45,527,530 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	45,506,334 - 45,529,481 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	49,972,583 - 49,978,185 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PSMD6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	25,044,616 - 25,056,938 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	25,027,762 - 25,056,813 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	141,757,216 - 141,769,700 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Psmd6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624888	1,883,445 - 1,903,011 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624888	1,883,365 - 1,903,011 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005335323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000012571 ⟹ ENSSTOP00000011269

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936637	2,403,450 - 2,416,917 (+)	Ensembl

RefSeq Acc Id:

XM_005335323 ⟹ XP_005335380

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	164,013,905 - 164,024,218 (+)	NCBI
SpeTri2.0	NW_004936637	2,403,456 - 2,413,772 (+)	NCBI

Sequence:

show sequence

TTTGTCCGACTCCTCCCGCTTCCGCTGCTGCAGTCGCCGCGCGTCGGAGCCGGGTTTGTTTCTGTCCGCTGTCCCCCCGGCCGCCGCGATGCCGCTGGAGAACCTGGAGGAGGAGGGTCTGCCCAAGA
ACCCCGACCTGCGCATCGCGCAGCTGCGCTTCCTGCTCAGCCTGCCGGAGCACCGCGGGGACGCGGCGGTGCGCGAGGAGCTGATGGCCGCGGTCCGCGACAACAACATGGCTCCTTACTACGAAGCC
TTGTGCAAATCCCTCGACTGGCAGATGGACATGGACCTGCTCAATAAAATGAAGAAGGCCAATGAGGAGGAGTTGAAACGTTTGGATGAGGAGCTGGAAGATGCAGAGAAGAACCTGGGGGAGAGTGA
GATTCGAGATGCCATGATGGCAAAAGCCGAGTACCTCTGTCGGATAGGCGATAAGGAGGGAGCTCTGACTGCCTTTCGTAAGACATACGACAAAACTGTGGCCCTGGGTCACCGCCTGGACATTGTAT
TCTATCTCCTTCGGATTGGTCTGTTTTATATGGATAATGATCTTATCACCCGAAACACAGAAAAGGCCAAAAGTTTAATAGAAGAAGGAGGAGACTGGGACAGAAGGAACCGCCTGAAGGTTTACCAG
GGTCTCTACTGTGTGGCCATTAGAGATTTTAAACAGGCAGCTGAGCTCTTTCTCGACACCGTCTCGACGTTTACCTCCTATGAGCTCATGGATTACAAGACGTTTGTGACTTACACTGTCTACGTCAG
CATGATTGCCTTAGAGAGACCAGACCTCAGGGAGAAGGTCATTAAAGGAGCAGAGATCCTTGAAGTGTTGCACAGTCTTCCAGCAGTTCGGCAGTACCTCTTTTCTCTTTACGAATGTCGTTACTCTG
TTTTCTTCCAATCATTAGCGGTTGTGGAACAGGAAATGAAAAAGGATTGGCTTTTTGCTCCTCATTATCGATACTATGTAAGAGAAATGAGAATTCACGCCTACAGCCAGCTGCTGGAATCCTACAGG
TCCTTAACCCTGGGCTACATGGCAGAAGCATTTGGTGTCGGAGTGGAATTCATTGATCAGGAACTGTCCAGATTTATTGCCGCTGGGAGACTACACTGCAAAATTGATAAAGTGAATGAAATAGTGGA
GACCAACAGACCTGATAGCAAGAACTGGCAGTACCAAGAAACTATCAAGAAAGGAGATCTGCTACTAAACAGAGTTCAGAAACTTTCCAGAGTAATTAATATGTAAAGTCATTTGAACAAAGGATTTT
CTTCTGAGTAATTGGAATTTTTATAGCTTATTTCACTATGTGCCCAGTTCACCTTATAAAATAAATACTACATTGTTGTTTCA

hide sequence


Protein RefSeqs	XP_005335380	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000011269.2
GenBank Protein	KAG3279217	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005335380 ⟸ XM_005335323

- UniProtKB:

I3MJE7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVREELMAAVRDNNMAPYYEALCKSLDWQMDMDLLNKMKKANEEELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTY
DKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAV
RQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLS
RVINM

hide sequence

Ensembl Acc Id:

ENSSTOP00000011269 ⟸ ENSSTOT00000012571

Protein Domains

PCI

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000012571	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000012571.3	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.570	UniProtKB/TrEMBL
InterPro	PCI_dom	UniProtKB/TrEMBL
	Rpn7/CSN1	UniProtKB/TrEMBL
	Rpn7_N	UniProtKB/TrEMBL
	RPN7_PSMD6_C	UniProtKB/TrEMBL
	TPR-like_helical_dom_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	Psmd6	ENTREZGENE
PANTHER	PTHR14145	UniProtKB/TrEMBL
	PTHR14145:SF1	UniProtKB/TrEMBL
Pfam	PCI	UniProtKB/TrEMBL
	RPN7	UniProtKB/TrEMBL
	RPN7_PSMD6_C	UniProtKB/TrEMBL
PROSITE	PCI	UniProtKB/TrEMBL
SMART	PINT	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
	SSF48452	UniProtKB/TrEMBL
UniProt	I3MJE7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - CTD