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Gene: Usp22 (ubiquitin specific peptidase 22) Ictidomys tridecemlineatus

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Symbol:

Usp22

Name:

ubiquitin specific peptidase 22

RGD ID:

12727364

Description:

ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); INVOLVED IN chromatin remodeling (inferred); G2/M transition of mitotic cell cycle (inferred); positive regulation of DNA-templated transcription (inferred); PARTICIPATES IN histone modification pathway; RNA polymerase II transcription initiation pathway; FOUND IN SAGA complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ubiquitin carboxyl-terminal hydrolase 22

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	62,248,926 - 62,287,018 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936741	580,224 - 618,628 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936741	580,230 - 618,322 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp22	Squirrel	chromatin remodeling	involved_in	IEA	GO:0010485\|GO:0140936	150520179		GOC	GO_REF:0000108
Usp22	Squirrel	G2/M transition of mitotic cell cycle	involved_in	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	positive regulation of DNA-templated transcription	involved_in	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	positive regulation of mitotic cell cycle	involved_in	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	positive regulation of type I interferon production	involved_in	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	protein deubiquitination	involved_in	IEA	InterPro:IPR001394	150520179		InterPro	GO_REF:0000002
Usp22	Squirrel	protein deubiquitination	involved_in	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	protein deubiquitination	acts_upstream_of_or_within	IEA	UniProtKB:Q5DU02\|ensembl:ENSMUSP00000041263	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	proteolysis	involved_in	IEA	UniProtKB-KW:KW-0645	150520179		UniProt	GO_REF:0000043
Usp22	Squirrel	regulation of transcription by RNA polymerase II	involved_in	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp22	Squirrel	SAGA complex	part_of	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp22	Squirrel	cysteine-type deubiquitinase activity	contributes_to	ISO	RGD:1321210	9068941	PMID:18206973	UniProtKB	PMID:18206973
Usp22	Squirrel	cysteine-type deubiquitinase activity	enables	IEA	UniRule:UR000880756	150520179		UniProt	GO_REF:0000104
Usp22	Squirrel	cysteine-type deubiquitinase activity	enables	IEA	EC:3.4.19.12	150520179		UniProt	GO_REF:0000003
Usp22	Squirrel	cysteine-type deubiquitinase activity	enables	IEA	UniProtKB:Q5DU02\|UniProtKB:Q9UPT9\|ensembl:ENSMUSP00000041263\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	cysteine-type deubiquitinase activity	enables	IEA	InterPro:IPR001394\|InterPro:IPR018200	150520179		InterPro	GO_REF:0000002
Usp22	Squirrel	cysteine-type peptidase activity	enables	IEA	UniProtKB-KW:KW-0788	150520179		UniProt	GO_REF:0000043
Usp22	Squirrel	enzyme binding	enables	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	histone H2A deubiquitinase activity	enables	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	histone H2B deubiquitinase activity	enables	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	histone H4 acetyltransferase activity	contributes_to	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	150520179		UniProt	GO_REF:0000043
Usp22	Squirrel	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
Usp22	Squirrel	peptidase activity	enables	IEA	UniProtKB-KW:KW-0645	150520179		UniProt	GO_REF:0000043
Usp22	Squirrel	protein binding	enables	ISO	UniProtKB:Q96AE4	9068941	PMID:21779003	IntAct	PMID:21779003
Usp22	Squirrel	protein binding	enables	ISO	UniProtKB:Q14CW9\|UniProtKB:Q96GX2	9068941	PMID:27601583	UniProt	PMID:27601583
Usp22	Squirrel	protein binding	enables	ISO	UniProtKB:O95429\|UniProtKB:Q14CW9\|UniProtKB:Q5JR59-3\|UniProtKB:Q9NRN7	9068941	PMID:32296183	IntAct	PMID:32296183
Usp22	Squirrel	protein binding	enables	ISO	UniProtKB:Q14CW9	9068941	PMID:18206972	UniProt	PMID:18206972
Usp22	Squirrel	protein binding	enables	ISO	UniProtKB:Q96JN0	9068941	PMID:29628311	ARUK-UCL	PMID:29628311
Usp22	Squirrel	protein binding	enables	ISO	UniProtKB:Q13469	9068941	PMID:24561192	IntAct	PMID:24561192
Usp22	Squirrel	protein binding	enables	ISO	UniProtKB:Q9NRN7	9068941	PMID:19615732, PMID:25416956, PMID:28514442, PMID:33961781	IntAct	PMID:19615732\|PMID:25416956\|PMID:28514442\|PMID:33961781
Usp22	Squirrel	transcription coactivator activity	enables	IEA	UniProtKB:Q9UPT9\|ensembl:ENSP00000261497	150520179		Ensembl	GO_REF:0000107
Usp22	Squirrel	zinc ion binding	enables	IEA	InterPro:IPR001607	150520179		InterPro	GO_REF:0000002
Usp22	Squirrel	zinc ion binding	enables	IEA	UniProtKB-KW:KW-0863	150520179		UniProt	GO_REF:0000043

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp22	Squirrel	histone modification pathway		ISO	RGD:1321210	9068941		RGD	PMID:24647359\|REF_RGD_ID:9479061
Usp22	Squirrel	RNA polymerase II transcription initiation pathway		ISO	RGD:1321210	9068941		RGD	PMID:22426530\|REF_RGD_ID:9681728

PMID:22301074

Usp22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	62,248,926 - 62,287,018 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936741	580,224 - 618,628 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936741	580,230 - 618,322 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

USP22
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	20,999,596 - 21,043,419 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	20,999,596 - 21,043,760 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	20,902,909 - 20,946,324 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	20,843,498 - 20,886,944 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	20,843,501 - 20,886,944	NCBI
Celera	17	21,596,363 - 21,639,730 (+)	NCBI		Celera
Cytogenetic Map	17	p11.2	NCBI
HuRef	17	20,105,104 - 20,134,191 (-)	NCBI		HuRef
CHM1_1	17	20,912,612 - 20,956,003 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	20,948,437 - 20,992,181 (-)	NCBI		T2T-CHM13v2.0

Usp22
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	61,042,607 - 61,065,885 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	61,042,611 - 61,065,881 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	61,151,781 - 61,175,059 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	61,151,785 - 61,175,055 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	60,965,283 - 60,988,561 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	61,582,720 - 61,604,614 (-)	NCBI		MGSCv36	mm8
MGSCv36	11	60,969,222 - 60,991,116 (-)	NCBI		MGSCv36	mm8
Cytogenetic Map	11	B2	NCBI
cM Map	11	37.96	NCBI

Usp22
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	46,328,092 - 46,354,939 (-)	NCBI		GRCr8
mRatBN7.2	10	45,828,619 - 45,855,468 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	45,828,622 - 45,855,497 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	50,533,750 - 50,557,825 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	50,024,143 - 50,048,217 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	45,527,710 - 45,551,785 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	47,429,201 - 47,453,298 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	47,429,002 - 47,453,442 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	47,203,849 - 47,227,946 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	47,303,727 - 47,327,738 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	47,315,918 - 47,341,370 (-)	NCBI
Celera	10	45,085,173 - 45,109,272 (-)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

Usp22
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955577	978,152 - 1,002,480 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955577	979,317 - 1,002,478 (-)	NCBI	ChiLan1.0	ChiLan1.0

USP22
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	50,346,675 - 50,390,168 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	55,215,283 - 55,258,620 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	30,606,845 - 30,650,281 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	35,468,177 - 35,511,672 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	35,468,177 - 35,511,672 (+)	Ensembl	panpan1.1		panPan2

USP22
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	42,493,776 - 42,519,740 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	42,496,472 - 42,540,378 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	42,586,089 - 42,678,063 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	42,555,402 - 42,647,432 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	42,594,246 - 42,647,601 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	42,521,953 - 42,613,962 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	42,469,373 - 42,561,372 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	42,661,849 - 42,753,883 (-)	NCBI		UU_Cfam_GSD_1.0

USP22
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	61,271,641 - 61,308,270 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	61,273,939 - 61,308,381 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

USP22
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	19,110,710 - 19,151,565 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	19,107,508 - 19,151,603 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	1,608,381 - 1,661,766 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Usp22
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624849	4,515,584 - 4,557,972 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624849	4,516,849 - 4,557,656 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_005339442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000028952 ⟹ ENSSTOP00000020090

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936741	580,224 - 618,628 (+)	Ensembl

RefSeq Acc Id:

XM_005339442 ⟹ XP_005339499

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	62,248,926 - 62,287,018 (-)	NCBI
SpeTri2.0	NW_004936741	580,230 - 618,322 (+)	NCBI

Sequence:

show sequence

GCCCCCGATGGTCTCCCGGCCTGAGCCCGAGGGCGAGGCCATGGACGCCGAGCTCTCGGTGGCGCCGCCGGGCTGCTCGCACCTGGGCAGCTTCAAGGTGGACAACTGGAAACAGAACCTGCGGGCCA
TCTACCAGTGCTTCGTGTGGAGCGGCACCGCGGAGGCCCGCAAGCGCAAGGCAAAGTCCTGCGTCTGCCATGTCTGTGGCGTCCACCTGAACCGTCTCCACTCTTGCCTCTACTGCGTCTTCTTTGGC
TGTTTCAATAAGAAACACATCCACGAACACGCCAAGTCCAAGCGGCACAACCTGGCCATCGATCTCACGTATGGAGGCATCTATTGCTTTTTGTGTCAGGACTACATCTATGACAGAGACATGGAAAT
AATTGCCAAAGAGGAACAGCGGAAGGCTTGGAAGATGCAAGGTGCTGGAGAGAAGTTTTCAACTTGGGAACCAACCAAACGGGAGCTGGAACTGCTGAAACACAATCCTAAAAGGAGGAAGATCACCT
CTAACTGCACCATAGGTCTGCGAGGGCTCATCAACCTTGGGAACACGTGCTTCATGAACTGCATCGTCCAGGCTCTGACCCACACACCGCTCCTGCGTGACTTCTTCCTGTCTGACAGACACCGGTGT
GAGATGCAGAGCCCCAGCTCCTGCCTGGTCTGTGAGATGTCCTCACTCTTCCAGGAGTTCTACTCTGGGCACCGCTCCCCTCACATCCCCTACAAGCTGCTGCACCTGGTGTGGACCCACGCACGCCA
CCTGGCCGGCTATGAACAGCAGGACGCGCACGAGTTCCTCATCGCGGCCCTGGACGTCCTTCACCGGCATTGCAAAGGTGATGACAATGGGAAGAAGGCCAACAACCCCAACCACTGCAACTGCATCA
TTGACCAGATCTTCACAGGCGGGCTGCAGTCCGACGTCACGTGCCAGGTCTGCCACGGCGTCTCCACCACCATAGACCCCTTCTGGGACATCAGCTTGGATCTGCCTGGCTCCTCCACCCCGTTCTGG
CCCCTGAGCCCGGGCAGCGAGGGCAGTGTGGTCAACGGGGAGAGCCACACCTCGGGCACCACAACACTCACCGACTGCCTGCGGAGATTTACCAGACCAGAGCACTTGGGAAGCAGTGCCAAGATCAA
ATGCAGTGGGTGCCACAGCTACCAGGAGTCCACCAAGCAGCTCACCATGAAGAAGCTGCCCATTGTGGCCTGCTTTCATCTTAAACGATTTGAGCACTCGGCCAAGCTGAGGCGGAAGATCACCACGT
ACGTGTCCTTCCCCCTGGAGCTGGACATGACACCCTTCATGGCCTCCAGTAAAGAAAGCAGGATGAACGGGCAGTACCAGCAGCCCACAGACAGCCTCAGCAACGACAACAAGTACTCCCTGTTTGCT
GTCGTTAACCACCAAGGGACCTTGGAGAGTGGCCACTACACCAGCTTCATCCGTCAGCACAAAGATCAGTGGTTCAAGTGTGATGATGCTATCATCACCAAGGCCAGCATCAAGGACGTGCTGGACAG
CGAAGGATACCTGCTGTTCTACCACAAACAGTTCCTGGAGTACGAGTAGCCTCATCCACAGCTGGTCAGAGAAAAGGAGGGCGAGGAGTTGGCAAGCCTCACCAGAAGACCCCCAGCTTCCCCGACAT
GGCACCACCACGGCACCCCTCCTGTGTAGATGAGCCTGCACACGTGATCCTTCTGCACCCGGGAGTCAGGGGTCAGAGTGGACGTGAACCGCCCTCCCGAGCACACGTCAGGACGGTGCCCTGGATGG
GAAAGGAGCCGAGGGAGTCTGTCACTGGCGTCTCTCCTGTGCTCCTCAAAACTGGGAGATCTGGGGTTGGGGCACCCTCGTGGCATGAAACTGCCTCTGCCTGGTGCTTCCTTTTGTCCTACCACGCA
CACAGTTTAAAAAGGTGCCCACCTGATGAAAATAATGGGTCCACCGCGTGTAGACCAAGGTGGAGGCCAGGGCAGAGGCCTGGGGCGGCTGCGGGCTAAGTGTGGGCGGGGAGCCCATCCTCCCACTG
TCTCCTGCAGCTGGAGGCTGACCCGGGGCCCAGGGCCTGGGGGCGCTGGTGCAGGTTCCCAGCACGTCTGCTCTGCAGGTAATTTAGTGTCAACTGCATGTGGAAGCATCAGCCCAGGTGTTCTCTCA
GTTTTCTAGAAATAGACATTTTCTTATCCCCTTTCCCTTTTCTCTTTTTCCAAGATGGTGAATTTCATAAATGTAATAATAGTAAAGTGAATGACTATTGAGTTTATAATGAAATCTAGATCATTTCT
TTATTCTCAAGAGTGAGTCTTGCTTTTTAATTGGTGCTGTTCTGTTGTGCCCTTTCCCACCCCGCTCAGCCGCTCTCCCCCTTCTGTGGTTCGCAGCAGGCAGAGGTGGCGGAGGAGGACGGGGGACA
GGGCTGCAGCTCAGATCCAGTGTCTTGATCTTGGAGTCAACGGAGCGTTGTCCCGTGGTTCCATGGTCCCTTTCCCCCATTTTCCTCCTGATCTTTGGTCTTGCTGCCTGGGCAGGGCCGCGTGGTGG
CTGGTGTGTGGGGTCTGAAGCTGAGTGGCCCTGCTGGAGGCCAGGTGCCTCTCTGCACTTGCTGTGACTTCAGTTGGAACAGGAATGAAATGCTTTTGTGATGAGGTGGTTTCGGAGCTGGTTGAGGA
AGTTCCTTGTAAGATATCTTGCATGTATCTAGCTATTCAAACCCAAACTTAGATTGTTAGTCCACTTTTGAGAAATCACAACCTGGGGGCCTGGGGACGGAAGCGCTATTGGGACCTAGTTTGTGAAT
GGCCATCTCTGCAGCTCTGCCTGCCCGGGAGCGCTGTCTGCATGGACTGCAGGGTCCTGGTGTTGGGGAGAAGGAAGTGAGCGGTCTCAGGGCTAGCTAAAGAGCCGACGGGTGAGAATCTGAGGCTC
TGTGGGCTCTAGGGTCTCTGCTATAGGTAATATGTGAACAGTGAGTTTGGCTGTGTTCCAGTAGTCCTTTATTTATGGGCCCTGAAATTCGAATTTTGTATAATTTACATGTGTCAAGAAAATAAATT
TTTTTTAACTATTTGAAAATAAGAAAATTTCTCATAGTTGACAGGCCACACAAAGGTAGGCAGGGGACCTGAGCTGAGAAGCTGCTGCTTACTCAAAACCCAAGAAACCCAAACACCTGCCACGGGGT
CGGCAGGTACAGTGGAGCCTCGTGGTGCGGTCTGTGCACACTTCCCAGTTCATCTCTGTTGTGTTTCTGTGTTCAAAGAATATAAACTAAAGCATGTGTTTAAATAAGCATTATTGGAAAGCATGGAC
GGCCAGGTTCTCAGGCACAGCCCCAGGCGGCCGTCTGTGTACTGTGCTGTGAAGATCTTCTTGGGAACAGATTTTTGTCTTTTAATCAGGAACAAGTCTTTTGGAAAGGAGGCTGAACTGAAGGCAGC
CTGCAGGCGTCTGAACGGGGAGCCTCAGCACCCTGACTTGCAGGGTGTACAGACGCAAGTGTGAAGCCAGCAGGTGAGCCGGCTGGGCTTTCTGGCCCGTCACCCTTGGCCGGGCTGGGCCTGTGTCC
TCCGTGGCCACACCCCTCCGGTCTCAGCTTGTGCCACTGTACTGGGACTGTAGAAGGGGAGGAAGATGGAGCTGCGCTCCTCTTTATAGGCACCATTGGAGACGTCCGTATTCAGGTGGATTCCCTCC
TTTACTGAGGCTTTGGCACTCTTAGCACTTAGCTCTGTCCAGCTGGGAGACCCCTGGACACTCAGCTCGTGTTGGGCCTTGCCCTCAGCCAGGACCCTCAGCACTGGGTCCATGTTTCTGCTCATGTG
ACTTGACTTTGTGAGGAGCAGCATATTTATTTGATGGGTTTAGGGATCCCTTGTTTTAGCTCCCCGTCTGGCTCGTCAGTCAGGAGAACGGTTTTACCATTTCCCAGTTAACCACCCTGTGTAGGGAG
GTGTTCAGATTGTCCCAAAGTTGTCTTACCGTGAAGGGACTCGTTGGGTGACACCCCCTGCACGTTCATGACCGTGTGCCAGGAAGAGTCTGCACGTCTGAGATGCTGGCTGTCATTCAGTGCTTCAT
GGTGAGACAGGTGGACTCGCCCTCTTCAGGAGTCTGGAGGCAAGGTTTTTGAGCTGGGTGGAGTGCTGGGGGCCTGGGTGGCCTGAGGGTGGTGTGGACAGCGTCCCTGTGCCTGGGACTCCTCAGCC
AGGCAGCAGCCAGGGGCCGGGCCCGGGCTCTGCTCCCCTGGACCCCAGGATGGCCCCTGCGCGTCCCTGTTAGCAGCATCCCTGAGACATACCTGAGTGCTCTTGTGTTTTGGCTTGGTGTGTATGCT
TTGACTTGTGTAAAATCGCAGTTCTTTTGACAATTCAAAGTGACTCGTTTCATTTACTATAACTTTAAAAACAAAAATTGTAAAAAAAAAAAAAATTCCAATGATTGTGTTGTGGTTGGAGATTTTAT
TACCAAGATGTTTACACCTGCCCTTTCCCTGTCGTTTTGAGGGGCTGTTTGGCGCTCTGCTCCCTGATGGCTTGTAGTCTTTCCTATGTCATAATAAAGCTACGTTTTATTCTGCA

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Protein RefSeqs	XP_005339499	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000020090.2
GenBank Protein	KAG3270353	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005339499 ⟸ XM_005339442

- UniProtKB:

I3N6U4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVSRPEPEGEAMDAELSVAPPGCSHLGSFKVDNWKQNLRAIYQCFVWSGTAEARKRKAKSCVCHVCGVHLNRLHSCLYCVFFGCFNKKHIHEHAKSKRHNLAIDLTYGGIYCFLCQDYIYDRDMEIIA
KEEQRKAWKMQGAGEKFSTWEPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFLSDRHRCEMQSPSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLA
GYEQQDAHEFLIAALDVLHRHCKGDDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGSVVNGESHTSGTTTLTDCLRRFTRPEHLGSSAKIKCS
GCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLSNDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLDSEG
YLLFYHKQFLEYE

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Ensembl Acc Id:

ENSSTOP00000020090 ⟸ ENSSTOT00000028952

Protein Domains

UBP-type USP

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000023814	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000028952.2	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
	Cysteine proteinases	UniProtKB/TrEMBL
InterPro	Papain-like_cys_pep_sf	UniProtKB/TrEMBL
	Peptidase_C19_UCH	UniProtKB/TrEMBL
	Ub_carboxyl-term_hydrolase	UniProtKB/TrEMBL
	USP_CS	UniProtKB/TrEMBL
	USP_dom	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_UBP	UniProtKB/TrEMBL
NCBI Gene	Usp22	ENTREZGENE
PANTHER	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE	UniProtKB/TrEMBL
	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22	UniProtKB/TrEMBL
Pfam	UCH	UniProtKB/TrEMBL
	zf-UBP	UniProtKB/TrEMBL
PROSITE	USP_1	UniProtKB/TrEMBL
	USP_2	UniProtKB/TrEMBL
	USP_3	UniProtKB/TrEMBL
	ZF_UBP	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
	SSF54001	UniProtKB/TrEMBL
UniProt	I3N6U4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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