Myh10 (myosin heavy chain 10) - Rat Genome Database

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Gene: Myh10 (myosin heavy chain 10) Ictidomys tridecemlineatus
Analyze
Symbol: Myh10
Name: myosin heavy chain 10
RGD ID: 12725394
Description: ENCODES a protein that exhibits actin filament binding (ortholog); identical protein binding (ortholog); microfilament motor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament bundle assembly (ortholog); actin filament bundle distribution (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); congenital fibrosis of the extraocular muscles (ortholog); Developmental Disabilities (ortholog); FOUND IN axon (ortholog); brush border (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: myosin heavy chain 10, transcript variant X1; myosin heavy chain 10, transcript variant X2; myosin heavy chain 10, transcript variant X3; myosin heavy chain 10, transcript variant X4; myosin heavy chain 10, transcript variant X5; myosin heavy chain 10, transcript variant X6; myosin heavy chain 10, transcript variant X7; myosin-10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,223,102 - 48,358,045 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,694,102 - 1,832,364 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,697,283 - 1,832,571 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Myh10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,223,102 - 48,358,045 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,694,102 - 1,832,364 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,697,283 - 1,832,571 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYH10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,474,212 - 8,630,725 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,474,207 - 8,631,376 (-)EnsemblGRCh38hg38GRCh38
GRCh37178,377,530 - 8,534,043 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,318,255 - 8,474,761 (-)NCBINCBI36Build 36hg18NCBI36
Build 34178,318,254 - 8,474,761NCBI
Celera178,408,358 - 8,564,898 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,276,713 - 8,433,166 (-)NCBIHuRef
CHM1_1178,386,377 - 8,542,853 (-)NCBICHM1_1
T2T-CHM13v2.0178,380,372 - 8,536,822 (-)NCBIT2T-CHM13v2.0
Myh10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,581,228 - 68,707,451 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,582,385 - 68,707,458 (+)EnsemblGRCm39 Ensembl
GRCm381168,691,915 - 68,816,626 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,691,559 - 68,816,632 (+)EnsemblGRCm38mm10GRCm38
MGSCv371168,505,417 - 68,630,126 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,508,162 - 68,632,737 (+)NCBIMGSCv36mm8
Celera1175,631,165 - 75,761,610 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1141.95NCBI
Myh10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81053,891,955 - 54,024,032 (+)NCBIGRCr8
mRatBN7.21053,393,901 - 53,525,174 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,394,389 - 53,525,165 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1058,054,246 - 58,186,532 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,543,278 - 57,675,562 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01053,052,353 - 53,184,133 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,274,910 - 55,406,738 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,275,411 - 55,406,732 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01055,017,110 - 55,148,300 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,445,288 - 55,576,096 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11055,458,910 - 55,589,717 (+)NCBI
Celera1052,561,720 - 52,692,270 (+)NCBICelera
Cytogenetic Map10q24NCBI
Myh10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,298,527 - 8,427,459 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,298,514 - 8,427,459 (+)NCBIChiLan1.0ChiLan1.0
MYH10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21965,118,242 - 65,274,685 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11769,927,439 - 70,084,120 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01743,023,922 - 43,180,159 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11747,756,244 - 47,912,747 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1747,761,322 - 47,911,192 (+)Ensemblpanpan1.1panPan2
MYH10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,239,800 - 33,360,459 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,241,266 - 33,360,934 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,375,328 - 33,497,290 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,342,579 - 33,463,814 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,342,582 - 33,463,639 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,309,962 - 33,431,940 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,265,077 - 33,387,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,444,924 - 33,565,595 (-)NCBIUU_Cfam_GSD_1.0
MYH10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11253,647,579 - 53,781,552 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21256,123,499 - 56,235,665 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYH10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1167,837,527 - 7,989,687 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl167,835,843 - 7,989,788 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605913,394,355 - 13,546,918 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myh10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478611,040,951 - 11,185,627 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478611,039,436 - 11,190,935 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000010791   ⟹   ENSSTOP00000009683
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365951,698,885 - 1,824,744 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000036566   ⟹   ENSSTOP00000025279
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365951,694,102 - 1,832,364 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000039911   ⟹   ENSSTOP00000024407
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365951,694,102 - 1,832,364 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000043022   ⟹   ENSSTOP00000031025
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365951,694,102 - 1,832,364 (-)Ensembl
RefSeq Acc Id: XM_005332861   ⟹   XP_005332918
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560248,223,183 - 48,357,972 (-)NCBI
SpeTri2.0NW_0049365951,697,283 - 1,832,222 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021731390   ⟹   XP_021587065
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560248,223,183 - 48,358,045 (-)NCBI
SpeTri2.0NW_0049365951,697,283 - 1,832,222 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021731391   ⟹   XP_021587066
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560248,223,102 - 48,350,587 (-)NCBI
SpeTri2.0NW_0049365951,697,286 - 1,832,571 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021731394   ⟹   XP_021587069
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560248,223,102 - 48,357,972 (-)NCBI
SpeTri2.0NW_0049365951,697,286 - 1,832,222 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021731396   ⟹   XP_021587071
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560248,223,183 - 48,357,972 (-)NCBI
SpeTri2.0NW_0049365951,697,283 - 1,832,222 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040269432   ⟹   XP_040125366
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560248,223,102 - 48,350,587 (-)NCBI
RefSeq Acc Id: XM_040269433   ⟹   XP_040125367
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560248,224,697 - 48,350,587 (-)NCBI
RefSeq Acc Id: XM_040269434   ⟹   XP_040125368
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560248,226,056 - 48,350,587 (-)NCBI
RefSeq Acc Id: XP_005332918   ⟸   XM_005332861
- Peptide Label: isoform X6
- UniProtKB: A0A287CT06 (UniProtKB/TrEMBL),   I3MG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021587071   ⟸   XM_021731396
- Peptide Label: isoform X5
- UniProtKB: I3MG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021587065   ⟸   XM_021731390
- Peptide Label: isoform X1
- UniProtKB: A0A287CVH8 (UniProtKB/TrEMBL),   I3MG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021587066   ⟸   XM_021731391
- Peptide Label: isoform X1
- UniProtKB: A0A287CVH8 (UniProtKB/TrEMBL),   I3MG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021587069   ⟸   XM_021731394
- Peptide Label: isoform X4
- UniProtKB: A0A287DBS9 (UniProtKB/TrEMBL),   I3MG45 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040125366   ⟸   XM_040269432
- Peptide Label: isoform X2
- UniProtKB: I3MG45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040125367   ⟸   XM_040269433
- Peptide Label: isoform X3
- UniProtKB: I3MG45 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040125368   ⟸   XM_040269434
- Peptide Label: isoform X7
- UniProtKB: I3MG45 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000009683   ⟸   ENSSTOT00000010791
Ensembl Acc Id: ENSSTOP00000024407   ⟸   ENSSTOT00000039911
Ensembl Acc Id: ENSSTOP00000031025   ⟸   ENSSTOT00000043022
Ensembl Acc Id: ENSSTOP00000025279   ⟸   ENSSTOT00000036566
Protein Domains
Myosin motor   Myosin N-terminal SH3-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010770 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010791.3 UniProtKB/TrEMBL
  ENSSTOT00000036566.1 UniProtKB/TrEMBL
  ENSSTOT00000039911.1 UniProtKB/TrEMBL
  ENSSTOT00000043022.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.10.287.1490 UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/TrEMBL
  1.20.5.4820 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  2.30.30.360 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  6.10.250.2420 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
InterPro IQ_motif_EF-hand-BS UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/TrEMBL
  Myosin_tail UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Myh10 ENTREZGENE
PANTHER MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/TrEMBL
  MYOSIN-10 UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/TrEMBL
  PF00612 UniProtKB/TrEMBL
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/TrEMBL
SMART MYSc UniProtKB/TrEMBL
  SM00015 UniProtKB/TrEMBL
Superfamily-SCOP Myosin rod fragments UniProtKB/TrEMBL
  Myosin S1 fragment, N-terminal domain UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A287CT06 ENTREZGENE, UniProtKB/TrEMBL
  A0A287CVH8 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DBS9 ENTREZGENE, UniProtKB/TrEMBL
  I3MG45 ENTREZGENE, UniProtKB/TrEMBL