Msh6<sup>m1Hubr</sup> (mutS homolog 6; ENU induced mutant 1, Hubr)

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Gene: Msh6^m1Hubr (mutS homolog 6; ENU induced mutant 1, Hubr) Rattus norvegicus

Symbol:	Msh6^m1Hubr
Name:	mutS homolog 6; ENU induced mutant 1, Hubr
RGD ID:	126848738
Description:	The Msh6 knockout allele was generated by ENU-driven mutagenesis on Crl:WI rats. The allele carried an ENU-induced premature stop codon in exon 4 of the Msh6 gene. ASSOCIATED WITH increased tumor incidence; premature death; ASSOCIATED WITH hereditary nonpolyposis colorectal cancer type 5; Microsatellite Instability
Type:	allele of Msh6
Is Marker For:	Strains: WI- Msh6^m1Hubr
Latest Assembly:	mRatBN7.2 - mRatBN7.2 Assembly
Position:	No map positions available.

Disease Annotations Click to see Annotation Detail View

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated

#	Reference Title	Reference Citation
1.	Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis.	van Boxtel R, etal., Carcinogenesis. 2008 Apr 15;.

Genomics

Related Rat Strains

The following Strains have been annotated to Msh6^m1Hubr

Expression

Sequence

Nucleotide Sequences

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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