Stk3 (serine/threonine kinase 3) - Rat Genome Database

Name: Stk3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Stk3 (serine/threonine kinase 3) Ictidomys tridecemlineatus

Analyze

Symbol:

Stk3

Name:

serine/threonine kinase 3

RGD ID:

12663636

Description:

ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); kinase activity (inferred); INVOLVED IN apoptotic process (ortholog); canonical Wnt signaling pathway (ortholog); cell differentiation involved in embryonic placenta development (ortholog); ASSOCIATED WITH Cohen syndrome (ortholog); genetic disease (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine/threonine kinase 3, transcript variant X1; serine/threonine kinase 3, transcript variant X2; serine/threonine kinase 3, transcript variant X3; serine/threonine-protein kinase 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	36,733,336 - 37,010,196 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	44,159,419 - 44,436,330 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	44,159,449 - 44,436,295 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cohen syndrome (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA,ISO)

canonical Wnt signaling pathway (IEA,ISO)

cell differentiation involved in embryonic placenta development (IEA,ISO)

cell population proliferation (IEA,ISO)

central nervous system development (IEA,ISO)

endocardium development (IEA,ISO)

epithelial cell proliferation (IEA,ISO)

extrinsic apoptotic signaling pathway via death domain receptors (IEA,ISO)

hepatocyte apoptotic process (IEA,ISO)

hippo signaling (IEA)

intracellular signal transduction (IEA)

JNK cascade (IEA,ISO)

negative regulation of canonical Wnt signaling pathway (IEA,ISO)

negative regulation of cell population proliferation (IEA,ISO)

negative regulation of epithelial cell proliferation (IEA,ISO)

negative regulation of organ growth (IEA,ISO)

neural tube formation (IEA,ISO)

organ growth (IEA,ISO)

phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA,ISO)

positive regulation of apoptotic process (IEA,ISO)

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (IEA,ISO)

positive regulation of fat cell differentiation (IEA,ISO)

positive regulation of JNK cascade (IEA,ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (IEA,ISO)

primitive hemopoiesis (IEA,ISO)

protein import into nucleus (IEA)

protein localization to centrosome (IEA)

protein stabilization (IEA,ISO)

protein tetramerization (IEA)

regulation of cell differentiation involved in embryonic placenta development (IEA,ISO)

regulation of MAPK cascade (IEA)

signal transduction (IEA)

Cellular Component

centrosome (IEA,ISO)

cytoplasm (IEA,ISO)

nucleus (IEA)

protein-containing complex (IEA)

Molecular Function

ATP binding (IEA)

identical protein binding (IEA)

kinase activity (IEA)

magnesium ion binding (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Stk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	36,733,336 - 37,010,196 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	44,159,419 - 44,436,330 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	44,159,449 - 44,436,295 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

STK3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	98,343,975 - 98,942,610 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	98,371,228 - 98,942,827 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	99,466,861 - 99,954,838 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	99,536,037 - 99,907,085 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	99,536,042 - 99,907,085	NCBI
Celera	8	95,652,680 - 96,023,711 (-)	NCBI		Celera
Cytogenetic Map	8	q22.2	NCBI
HuRef	8	94,670,086 - 95,157,575 (-)	NCBI		HuRef
CHM1_1	8	99,507,181 - 99,995,466 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	8	99,469,462 - 100,069,002 (-)	NCBI		T2T-CHM13v2.0

Stk3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	34,875,645 - 35,155,990 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	34,875,642 - 35,179,067 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	34,875,499 - 35,155,882 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	34,875,496 - 35,178,921 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	34,805,254 - 35,085,561 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	34,821,196 - 35,100,274 (-)	NCBI		MGSCv36	mm8
Celera	15	35,503,253 - 35,772,245 (-)	NCBI		Celera
Cytogenetic Map	15	B3.1	NCBI
cM Map	15	14.34	NCBI

Stk3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	67,938,341 - 68,208,472 (-)	NCBI		GRCr8
mRatBN7.2	7	66,053,209 - 66,323,292 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	66,052,345 - 66,323,233 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	67,942,463 - 68,211,608 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	70,144,143 - 70,414,225 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	70,017,776 - 70,274,776 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	73,617,926 - 73,883,896 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	73,618,644 - 73,883,812 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	73,793,705 - 74,055,204 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	70,308,195 - 70,597,445 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	70,447,334 - 70,618,175 (-)	NCBI
Celera	7	63,152,608 - 63,416,831 (-)	NCBI		Celera
Cytogenetic Map	7	q22	NCBI

Stk3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955417	14,095,694 - 14,381,607 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955417	14,098,851 - 14,381,553 (-)	NCBI	ChiLan1.0	ChiLan1.0

STK3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	115,664,689 - 116,170,207 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	91,344,435 - 91,711,597 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	95,098,185 - 95,465,324 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	8	97,278,139 - 97,592,727 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	97,355,173 - 97,708,437 (-)	Ensembl	panpan1.1		panPan2

STK3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	647,363 - 920,887 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	648,216 - 920,847 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	640,435 - 1,015,875 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	796,957 - 1,172,656 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	796,966 - 1,070,759 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	639,257 - 1,015,142 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	747,613 - 1,123,107 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	753,947 - 1,129,925 (-)	NCBI		UU_Cfam_GSD_1.0

STK3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	38,011,814 - 38,306,773 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	38,011,802 - 38,306,777 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	41,016,047 - 41,330,062 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

STK3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	93,374,528 - 93,698,143 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	93,374,517 - 93,697,758 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	47,027,424 - 47,360,853 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Stk3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624763	5,564,835 - 5,886,769 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624763	5,568,079 - 5,886,722 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005316308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021725081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021725084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040293823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040293824	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040293825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040293826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040293827	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000362	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000000651 ⟹ ENSSTOP00000000587

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936470	44,159,621 - 44,435,082 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000041409 ⟹ ENSSTOP00000027455

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936470	44,159,419 - 44,436,330 (+)	Ensembl

RefSeq Acc Id:

XM_005316308 ⟹ XP_005316365

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	36,733,336 - 37,010,196 (+)	NCBI
SpeTri2.0	NW_004936470	44,159,449 - 44,436,295 (+)	NCBI

Sequence:

show sequence

CGCGGCGGGGCGGGTGAGGAGGAGCAGCGCTCCCGAGCGGGGGGAGATCCGCCGCCGAGTTACA
GGAAAGTTGGTCCGAGTTTTGGGAGTTTCCCTCGGGCTCGGCCGGCCGGTGCCCCGGCTCCTTT
CCTCCCTCCGGCCTTTGTAGTCTCTCTTTCTGCTTCGGGCCGCCATGGAACAGCCGCCAGCGCC
TAAGAGTAAGCTAAAAAAGCTAAGTGAAGACAGTTTGACTAAGCAGCCTGAAGAAGTTTTTGAT
GTATTAGAGAAGCTTGGAGAAGGGTCTTATGGAAGTGTTTTTAAAGCAATACATAAGGAATCTG
GTCAAGTTGTTGCAATTAAACAGGTACCTGTTGAATCAGACCTTCAGGAAATAATCAAAGAAAT
TTCCATAATGCAACAATGTGACAGCCCGTATGTTGTAAAGTACTATGGCAGTTACTTTAAGAAC
ACAGACCTGTGGATTGTTATGGAGTACTGTGGAGCTGGCTCTGTCTCAGACATAATTAGATTAC
GAAACAAGACATTAACAGAAGATGAAATTGCAACCATTCTAAAATCTACATTGAAAGGATTAGA
ATATTTGCACTTTATGAGAAAAATACACAGAGATATAAAGGCTGGAAATATTCTCCTTAATACA
GAAGGACATGCAAAATTGGCAGATTTTGGAGTGGCTGGTCAGTTAACAGATACAATGGCAAAAC
GCAATACTGTGATAGGAACTCCATTTTGGATGGCTCCGGAGGTAATTCAAGAAATAGGATATAA
CTGTGTGGCTGACATCTGGTCACTTGGCATTACTTCTATAGAAATGGCTGAAGGGAAACCACCT
TATGCTGATATACATCCAATGAGGGCTATTTTTATGATTCCCACAAATCCACCACCAACATTCA
GGAAGCCCGAACTCTGGTCTGATGATTTTACCGATTTTGTTAAAAAGTGCTTAGTGAAGAATCC
TGAGCAGAGAGCTACTGCAACACAACTATTGCAGCATCATTTTATCAAGAATGCAAAACCTGTA
TCCATATTAAGAGATTTGATCACAGAAGCTATGGAAATCAAAGCTAAAAGACATGAAGAACAGC
AGCGAGAATTAGAAGAGGAAGAAGAAAATTCGGATGAAGATGAGCTGGATTCCCACACCATGGT
GAAGACTAGTTCAGAAAGTGTGGGCACAATGCGGGCTACGAGCACAATGAGTGAAGGAGCCCAG
ACCATGATTGAACATAACAGTACTATGTTAGAGTCTGACCTGGGGACCATGGTTATAAACAGTG
AAGATGAGGAAGAAGAAGATGGAACTATGAAAAGAAATGCAACTTCACCACAAGTACAAAGACC
ATCTTTCATGGACTACTTTGATAAGCAAGACTTCAAGAATAAGAATCATGAAAACTGTAATCAG
AACATGCATGAACCCTTCCCTATGTCCAAAAATGTTTTTCCTGATAACTGGAAAGTTCCTCAAG
ATGGAGACTTTGACTTTTTAAAAAATCTAAGTTTAGAAGAACTGCAGATGCGGTTAAAAGCACT
GGACCCCATGATGGAACGAGAAATAGAAGAACTTCGTCAAAGATACACTGCAAAAAGACAGCCT
ATTCTGGATGCAATGGATGCGAAGAAAAGAAGGCAGCAAAACTTTTGAGTCTAATTTCTCTGTT
TTATAGCTACTCTACAGACCAAGAAACCACTAAGAATTAAAAGGTTTTTTTTTAATCCCTAAGA
TTTATGCTCTACAGCTAGGCAAAGATCAAAAACTAATGATGGCACATACCTATGAAAGTTCCCA
AAAGACACAATTTACAATTGTTTCCACTGTGTTTTCATTTTTAAACTATGAGAACAATAGAAAT
GTGTTCTTCTCTCTCTCTGTCAGCTGAATACCAGCAATAAGACTGTTATGAAATGAAGGCTGTA
TTTAGAGACCTTGAAGATCCAAAGCTATTGTTTAATTGTATAGCAATGAAGGGCTTTATGTTAT
AATATTCTTTACTCTTATCTAGAAGCCTATTTATTATTGTATCTTCTTAGGTAGACTTATTTAT
TTATGCTATTTCACTTGGTTTTGTTTTTAAAAGACAGGACAGGATAGTTTTATGAAGGTTAACA
GTGATAATGTACAACCAAATTATATTTTAAGCAGGGAGCTAGGAGTACATACCTTGATTTCCAG
GATAGTTTTCCAATAAAAGCAAAGTGTAATAGCAGTAGTACCCAAATGGGCTAGGCTTTTTTAT
ATTGAAGCAATAAATTTTTACTTTTCAAAATTTTGATTTTTTGATTTTTGATATTTGGTACAAG
TAGAAATATATATATATATATATATATATATATATATATATTGTCAAACAGACCAATAATGTTT
AAAACCAAAGAAATGAATGAAATTTGCACAAAAGAAAGTATGGTAAATATTTTTAAAGAAATGA
AACCTTAAGACGAATGTAATTTGTTAATATTGTTTCATGTTTCTTGTATAGGTCTCTTAGCTAA
ACTGAATCAAACTGTAATAAGCTCATCAACCTTATTTCTGTGAAAATGTGCTCTGTATAGTCAC
AGGGCTTTTTGTTGATTTCATTTATTTCCTGGAATTGGTAAACATCATGTGCCTGATGATAACA
AAATAGCAAAAACATTTGTACTAAACTGTGCAAGCCTTGGGGCCTGGGGGGGGCGGGGATGGTT
AAAAGCATTAAAAAGAAACTCATTTCTAAGCTGAATGAACATTTGTATAATTGAACTGGGACCA
GTTGTTTCCTAAGCTACATATGGCCATCTTGACAGTGTTTGTTCTTTTCTGTCTTTAATTATTA
TGTGTAAGTCATAAAGAAAAATAAATTTTACTATGTCACCCAGAA

hide sequence

RefSeq Acc Id:

XM_040293823 ⟹ XP_040149757

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	36,733,336 - 37,009,054 (+)	NCBI

RefSeq Acc Id:

XM_040293824 ⟹ XP_040149758

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	36,733,336 - 36,947,275 (+)	NCBI

RefSeq Acc Id:

XM_040293825 ⟹ XP_040149759

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	36,800,559 - 37,009,054 (+)	NCBI

RefSeq Acc Id:

XM_040293826 ⟹ XP_040149760

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	36,792,579 - 37,009,054 (+)	NCBI

RefSeq Acc Id:

XM_040293827 ⟹ XP_040149761

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405303	36,792,544 - 37,009,054 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005316365	(Get FASTA)	NCBI Sequence Viewer
	XP_040149757	(Get FASTA)	NCBI Sequence Viewer
	XP_040149758	(Get FASTA)	NCBI Sequence Viewer
	XP_040149759	(Get FASTA)	NCBI Sequence Viewer
	XP_040149760	(Get FASTA)	NCBI Sequence Viewer
	XP_040149761	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000587.3
	ENSSTOP00000027455.1
GenBank Protein	KAG3273843	(Get FASTA)	NCBI Sequence Viewer
	KAG3273844	(Get FASTA)	NCBI Sequence Viewer
	KAG3273845	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005316365 ⟸ XM_005316308
- Peptide Label:	isoform X2
- UniProtKB:	A0A287D1S6 (UniProtKB/TrEMBL), I3LX35 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDL QEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILK STLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEV IQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVK KCLVKNPEQRATATQLLQHHFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDE LDSHTMVKTSSESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNAT SPQVQRPSFMDYFDKQDFKNKNHENCNQNMHEPFPMSKNVFPDNWKVPQDGDFDFLKNLSLEEL QMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF hide sequence

RefSeq Acc Id:	XP_040149757 ⟸ XM_040293823
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040149758 ⟸ XM_040293824
- Peptide Label:	isoform X3
- UniProtKB:	I3LX35 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040149761 ⟸ XM_040293827
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_040149760 ⟸ XM_040293826
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_040149759 ⟸ XM_040293825
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSSTOP00000000587 ⟸ ENSSTOT00000000651

RefSeq Acc Id:

ENSSTOP00000027455 ⟸ ENSSTOT00000041409

Protein Domains

Protein kinase SARAH

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000651	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000651.3	UniProtKB/TrEMBL
	ENSSTOT00000041409.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.4270	UniProtKB/TrEMBL
	4.10.170.10	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Mst1_SARAH_domain	UniProtKB/TrEMBL
	Mst2_SARAH	UniProtKB/TrEMBL
	p53_tetramer_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	SARAH_dom	UniProtKB/TrEMBL
NCBI Gene	Stk3	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN KINASE 3	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE TAO	UniProtKB/TrEMBL
Pfam	Mst1_SARAH	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	SARAH	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A287D1S6	ENTREZGENE, UniProtKB/TrEMBL
	I3LX35	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar