Tnpo3 (transportin 3) - Rat Genome Database

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Gene: Tnpo3 (transportin 3) Ictidomys tridecemlineatus
Analyze
Symbol: Tnpo3
Name: transportin 3
RGD ID: 12659278
Description: ENCODES a protein that exhibits identical protein binding (inferred); small GTPase binding (inferred); INVOLVED IN protein import into nucleus (inferred); ASSOCIATED WITH autosomal dominant limb-girdle muscular dystrophy type 2 (ortholog); genetic disease (ortholog); myofibrillar myopathy 5 (ortholog); FOUND IN annulate lamellae (inferred); cytoplasm (inferred); intracellular membrane-bounded organelle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transportin 3, transcript variant X1; transportin 3, transcript variant X2; transportin 3, transcript variant X3; transportin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511825,915,334 - 26,001,614 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365796,047,351 - 6,134,583 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365796,047,900 - 6,134,211 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tnpo3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511825,915,334 - 26,001,614 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365796,047,351 - 6,134,583 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365796,047,900 - 6,134,211 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNPO3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387128,954,185 - 129,056,193 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7128,954,180 - 129,055,173 (-)EnsemblGRCh38hg38GRCh38
GRCh377128,594,239 - 128,695,165 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367128,382,184 - 128,482,434 (-)NCBINCBI36Build 36hg18NCBI36
Build 347128,188,898 - 128,289,149NCBI
Celera7123,390,730 - 123,491,720 (-)NCBICelera
Cytogenetic Map7q32.1NCBI
HuRef7122,955,420 - 123,056,377 (-)NCBIHuRef
CHM1_17128,527,540 - 128,628,528 (-)NCBICHM1_1
T2T-CHM13v2.07130,267,070 - 130,368,954 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27127,977,977 - 128,078,965 (-)NCBI
Tnpo3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39629,540,826 - 29,609,918 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl629,540,826 - 29,609,886 (-)EnsemblGRCm39 Ensembl
GRCm38629,540,827 - 29,609,858 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl629,540,827 - 29,609,887 (-)EnsemblGRCm38mm10GRCm38
MGSCv37629,490,827 - 29,559,607 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36629,490,837 - 29,559,617 (-)NCBIMGSCv36mm8
Celera629,549,675 - 29,618,438 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.36NCBI
Tnpo3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8459,108,278 - 59,197,012 (-)NCBIGRCr8
mRatBN7.2458,142,954 - 58,220,365 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl458,143,001 - 58,220,433 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx463,126,422 - 63,203,551 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0459,042,589 - 59,119,719 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0457,444,471 - 57,521,602 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0456,820,023 - 56,897,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl456,820,023 - 56,897,338 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0456,587,184 - 56,664,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,422,446 - 56,499,733 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1456,682,348 - 56,760,325 (-)NCBI
Celera453,250,776 - 53,328,057 (-)NCBICelera
Cytogenetic Map4q22NCBI
Tnpo3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554799,740,805 - 9,831,339 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554799,739,927 - 9,831,276 (-)NCBIChiLan1.0ChiLan1.0
TNPO3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26165,758,971 - 165,863,548 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1717,769,217 - 17,871,151 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07120,906,238 - 121,008,216 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17133,430,495 - 133,531,771 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7133,430,490 - 133,531,774 (-)Ensemblpanpan1.1panPan2
TNPO3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,639,276 - 7,722,453 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,639,558 - 7,722,351 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha147,326,495 - 7,409,297 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,405,066 - 7,488,297 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl147,405,082 - 7,489,141 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,610,134 - 7,693,338 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,352,085 - 7,435,363 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0147,497,117 - 7,580,541 (+)NCBIUU_Cfam_GSD_1.0
TNPO3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1819,572,776 - 19,673,163 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11819,572,555 - 19,673,165 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21820,641,615 - 20,742,751 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNPO3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12197,554,484 - 97,654,289 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2197,553,519 - 97,653,889 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660425,747,926 - 5,847,780 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnpo3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247837,168,867 - 7,261,261 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247837,168,865 - 7,261,008 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000004900   ⟹   ENSSTOP00000004394
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365796,059,947 - 6,134,583 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000032504   ⟹   ENSSTOP00000026794
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365796,047,351 - 6,134,583 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000037709   ⟹   ENSSTOP00000024422
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365796,047,351 - 6,134,583 (+)Ensembl
RefSeq Acc Id: XM_005331120   ⟹   XP_005331177
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511825,915,334 - 26,001,614 (+)NCBI
SpeTri2.0NW_0049365796,047,900 - 6,134,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005331122   ⟹   XP_005331179
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511825,915,334 - 26,001,614 (+)NCBI
SpeTri2.0NW_0049365796,047,900 - 6,133,344 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005331177 (Get FASTA)   NCBI Sequence Viewer  
  XP_005331179 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004394.3
  ENSSTOP00000024422.1
  ENSSTOP00000026794.1
GenBank Protein KAG3277507 (Get FASTA)   NCBI Sequence Viewer  
  KAG3277508 (Get FASTA)   NCBI Sequence Viewer  
  KAG3277509 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005331177   ⟸   XM_005331120
- Peptide Label: isoform X1
- UniProtKB: A0A287CZX4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005331179   ⟸   XM_005331122
- Peptide Label: isoform X2
- UniProtKB: I3M529 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000004394   ⟸   ENSSTOT00000004900
Ensembl Acc Id: ENSSTOP00000024422   ⟸   ENSSTOT00000037709
Ensembl Acc Id: ENSSTOP00000026794   ⟸   ENSSTOT00000032504
Protein Domains
Exportin-1/Importin-beta-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004885 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004900.3 UniProtKB/TrEMBL
  ENSSTOT00000032504.1 UniProtKB/TrEMBL
  ENSSTOT00000037709.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Exportin-1/Importin-b-like UniProtKB/TrEMBL
  Importin_beta-like_NTR UniProtKB/TrEMBL
NCBI Gene Tnpo3 ENTREZGENE
PANTHER TRANSPORTIN 3 AND IMPORTIN 13 UniProtKB/TrEMBL
  TRANSPORTIN-3 UniProtKB/TrEMBL
Pfam Xpo1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A287CZX4 ENTREZGENE, UniProtKB/TrEMBL
  I3M529 ENTREZGENE, UniProtKB/TrEMBL